G. Loirand

发表

Two types of calcium currents in single smooth muscle cells from rat portal vein.

P. Pacaud, J. Mironneau, C. Mironneau, 1989, The Journal of physiology.

Activation of voltage-independent Ca2+ entry by noradrenaline involves cGMP in vascular myocytes.

P. Pacaud, G. Loirand, G. Grégoire, 1995, Cell calcium.

RhoE Is required for keratinocyte differentiation and stratification.

A. Ridley, D. Davies, J. Erasmus, 2009, Molecular biology of the cell.

Noradrenaline-activated heparin-sensitive Ca2+ entry after depletion of intracellular Ca2+ store in portal vein smooth muscle cells.

P. Pacaud, J. Mironneau, C. Mironneau, 1993, The Journal of biological chemistry.

Drug-Eluting Stents in Bifurcations: Bench Study of Strut Deformation and Coating Lesions

G. Finet, P. Pacaud, J. N'Guyen, 2010, Circulation. Cardiovascular interventions.

Human Urotensin II–Induced Contraction and Arterial Smooth Muscle Cell Proliferation Are Mediated by RhoA and Rho-Kinase

J. Bertoglio, P. Pacaud, V. Sauzeau, 2001, Circulation research.

Antagonism of α1-adrenoceptor agonist-induced responses by rilmenidine in vascular smooth muscle

P. Pacaud, G. Loirand, C. Cario-Toumaniantz, 1998 .

Results Arhgef 1 Is Required for Ang II – Mediated RhoA-Rho Kinase Activation in HCASMC

X. Jeunemaître, P. Pacaud, M. Azizi, 2022 .

WNK1 Regulates Vasoconstriction and Blood Pressure Response to &agr;1-Adrenergic Stimulation in Mice

S. Faure, X. Jeunemaître, J. Achard, 2011, Hypertension.

Understanding the Pathophysiology of Intracranial Aneurysm: The ICAN Project

R. Redon, P. Lebranchu, B. Isidor, 2017, Neurosurgery.

Calcium-dependence of the calcium-activated chloride current in smooth muscle cells of rat portal vein

P. Pacaud, J. Mironneau, C. Mironneau, 1992, Pflügers Archiv.

RESEARCH PAPER Protective role of the antidiabetic drug metformin against chronic experimental pulmonary hypertension

P. Pacaud, C. Sagan, C. Agard, 2009 .

Protective role of the antidiabetic drug metformin against chronic experimental pulmonary hypertension

P. Pacaud, C. Sagan, C. Agard, 2009, British journal of pharmacology.

n-3 PUFA prevent metabolic disturbances associated with obesity and improve endothelial function in golden Syrian hamsters fed with a high-fat diet

M. Krempf, X. Prieur, A. Meynier, 2011, British Journal of Nutrition.

Rho-Associated Protein Kinase Contributes to Early Atherosclerotic Lesion Formation in Mice

A. Tedgui, Z. Mallat, B. Esposito, 2003, Circulation research.

Role of Rho kinase signalling in healthy and varicose human saphenous veins

P. Pacaud, O. Baron, G. Loirand, 2002, British journal of pharmacology.

Sildenafil-Induced Revascularization of Rat Hindlimb Involves Arteriogenesis through PI3K/AKT and eNOS Activation

C. Fassot, P. Pacaud, D. Henrion, 2022, International journal of molecular sciences.

An analysis of the mechanisms involved in the okadaic acid-induced contraction of the estrogen-primed rat uterus.

P. Pacaud, J. Savineau, M. Norte, 1997, The Journal of pharmacology and experimental therapeutics.

Moringa oleifera Seeds Improve Aging-Related Endothelial Dysfunction in Wistar Rats

P. Pacaud, A. Tesse, G. Loirand, 2019, Oxidative medicine and cellular longevity.

Characterization of the P2Y‐purinoceptor involved in the ATP‐induced rise in cytosolic Ca2+ concentration in rat ileal myocytes

P. Pacaud, C. Frelin, G. Loirand, 1996, British journal of pharmacology.

PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension.

X. Prieur, C. Le May, J. Hadchouel, 2014, Atherosclerosis.

UT Receptor-Expressing Monocytes Urotensin II is a New Chemotactic Factor for and

P. Pacaud, N. Gervois, M. Rolli-Derkinderen, 2007 .

Ca2+ channel activation and membrane depolarization mediated by Cl− channels in response to noradrenaline in vascular myocytes

P. Pacaud, A. Baron, J. Mironneau, 1991, British journal of pharmacology.

GTP‐binding proteins mediate noradrenaline effects on calcium and chloride currents in rat portal vein myocytes.

P. Pacaud, J. Mironneau, C. Mironneau, 1990, The Journal of physiology.

Noradrenaline activates a calcium‐activated chloride conductance and increases the voltage‐dependent calcium current in cultured single cells of rat portal vein

P. Pacaud, J. Mironneau, C. Mironneau, 1989, British journal of pharmacology.

Large conductance calcium‐activated non‐selective cation channel in smooth muscle cells isolated from rat portal vein.

P. Pacaud, A. Baron, J. Mironneau, 1991, The Journal of physiology.

High Throughput Screen for Inhibitors of Rac1 GTPase by Flow Cytometry

Mark B. Carter, David C Murray, Zhaoping Liu, 2017, Multidimensional Flow Cytometry Techniques for Novel Highly Informative Assays.

Smooth Muscle Specific Rac1 Deficiency Induces Hypertension by Preventing p116RIP3‐Dependent RhoA Inhibition

S. Offermanns, M. Rolli-Derkinderen, J. Sandoval, 2014, Journal of the American Heart Association.

Smooth muscle Rac1 contributes to pulmonary hypertension

C. Guignabert, A. Tesse, V. Sauzeau, 2019, British journal of pharmacology.

Release of Ca2+ by noradrenaline and ATP from the same Ca2+ store sensitive to both InsP3 and Ca2+ in rat portal vein myocytes.

P. Pacaud, G. Loirand, 1995, The Journal of physiology.

RhoA and Rho kinase activation in human pulmonary hypertension: role of 5-HT signaling.

M. Humbert, E. Fadel, S. Eddahibi, 2009, American journal of respiratory and critical care medicine.

Vasomotor dysfunction early after exposure of normal rabbit arteries to an adenoviral vector.

D. Escande, P. Pacaud, A. Lafont, 1997, Human gene therapy.

Urotensin II is a New Chemotactic Factor for UT Receptor-Expressing Monocytes1

P. Pacaud, N. Gervois, M. Rolli-Derkinderen, 2007, The Journal of Immunology.

Urotensin II and atherosclerosis

P. Pacaud, M. Rolli-Derkinderen, G. Loirand, 2008, Peptides.

Spironolactone inhibition of contraction and calcium channels in rat portal vein

P. Pacaud, C. Dacquet, J. Mironneau, 1987, British journal of pharmacology.

Potassium channel activation, hyperpolarization, and vascular relaxation.

A. Schmidt, A. Walter, E. Buddecke, 1991, Zeitschrift fur Kardiologie.

Bronchial smooth muscle cell in asthma: where does it fit?

A. Magnan, F. Blanc, V. Sauzeau, 2022, BMJ Open Respiratory Research.

Pathways and receptors involved in peptide YY induced contraction of rat proximal colonic muscle in vitro

J. Galmiche, H. Blottière, C. Cherbut, 2000, Gut.

Nitric Oxide‐Induced Decrease in Calcium Sensitivity of Resistance Arteries Is Attributable to Activation of the Myosin Light Chain Phosphatase and Antagonized by the RhoA/Rho Kinase Pathway

S. Bolz, R. Derwand, U. Pohl, 2003, Circulation.

Autoanti-phosphatidylinositide antibodies specifically inhibit noradrenaline effects on Ca2+ and Cl- channels in rat portal vein myocytes.

M. Geffard, A. Baron, J. Mironneau, 1992, The Journal of biological chemistry.

Rho kinase inhibitors for pulmonary hypertension: waiting for clinical evidence

P. Pacaud, G. Loirand, 2010, European Respiratory Journal.

Extracellular Nucleotides Induce Arterial Smooth Muscle Cell Migration Via Osteopontin

P. Pacaud, M. Renault, C. Desgranges, 2001, Circulation research.

Targeting of Rac1 prevents bronchoconstriction and airway hyperresponsiveness

A. Magnan, F. Braza, V. Sauzeau, 2017, The Journal of allergy and clinical immunology.

Identification of Differentially Expressed Genes in Human Varicose Veins: Involvement of Matrix Gla Protein in Extracellular Matrix Remodeling

M. Le Cunff, L. Schurgers, C. Boularan, 2007, Journal of Vascular Research.

ARHGEF18 participates in Endothelial Cell Mechano-sensitivity in Response to Flow

Anne-Clémence Vion, G. Loirand, M. Rio, 2022, bioRxiv.

Ca2+ and Sr2+ entry induced Ca2+ release from the intracellular Ca2+ store in smooth muscle cells of rat portal vein.

P. Pacaud, G. Loirand, G. Grégoire, 1993, The Journal of physiology.

P. Pacaud, D. Henrion, L. Sabourin, 2008, Circulation research.

Dual effect of thrombin on voltage-dependent Ca2+ channels of portal vein smooth muscle cells.

P. Pacaud, A. Baron, J. Mironneau, 1993, Circulation research.

RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome.

R. Redon, E. Génin, C. Dina, 2018, European heart journal.

Nucleotide receptor P2u partially mediates ATP‐induced cell cycle progression of aortic smooth muscle cells

P. Pacaud, X. Pillois, C. Desgranges, 1996, Journal of cellular physiology.

ARF-independent inhibition of the carbachol-induced contractions by brefeldin A in intestinal smooth muscle.

P. Pacaud, P. Chardin, G. Loirand, 1997, The American journal of physiology.

Photoreleased inositol 1,4,5‐trisphosphate‐induced response in single smooth muscle cells of rat portal vein.

P. Pacaud, G. Loirand, G. Grégoire, 1994, The Journal of physiology.

Dependence of P2‐nucleotide receptor agonist‐mediated endothelium‐independent relaxation on ectonucleotidase activity and A2A‐receptors in rat portal vein

P. Pacaud, P. Vigne, C. Guibert, 1998, British journal of pharmacology.

Extract from Mimosa pigra attenuates chronic experimental pulmonary hypertension.

P. Pacaud, P. Tonnerre, C. Agard, 2013, Journal of ethnopharmacology.

In Vitro and In Vivo Approaches to Assess Rho Kinase Activity.

V. Sauzeau, G. Loirand, 2017, Methods in molecular biology.

AMPK Alpha 1-Induced RhoA Phosphorylation Mediates Vasoprotective Effect of Estradiol

B. Viollet, P. Pacaud, D. Henrion, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Bifurcation geometry remodelling of vessels in de novo and growing intracranial aneurysms: a multicenter study

F. Autrusseau, G. Boulouis, R. Bourcier, 2022, Journal of NeuroInterventional Surgery.

Rho proteins and vascular diseases.

P. Pacaud, V. Sauzeau, G. Loirand, 2005, Archives des maladies du coeur et des vaisseaux.

ATP raises [Ca2+]i via different P2-receptor subtypes in freshly isolated and cultured aortic myocytes.

P. Pacaud, C. Desgranges, G. Loirand, 1995, The American journal of physiology.

Synthesis and biological evaluation of 3-amino-, 3-alkoxy- and 3-aryloxy-6-(hetero)arylpyridazines as potent antitumor agents.

S. Sengmany, Eric Léonel, T. Martens, 2019, Bioorganic & medicinal chemistry letters.

Advanced glycation inhibition and protection against endothelial dysfunction induced by coumarins and procyanidins from Mammea neurophylla.

P. Pacaud, P. Tonnerre, M. Litaudon, 2014, Fitoterapia.

Rho-kinase Inhibitors: Pharmacomodulations on the Lead Compound Y-32885

D. Lesieur, P. Pacaud, C. Logé, 2002, Journal of enzyme inhibition and medicinal chemistry.

P2X7 receptor activation-induced contraction and lysis in human saphenous vein smooth muscle.

P. Pacaud, A. Ladoux, G. Loirand, 1998, Circulation research.

Opposing effects of noradrenaline on the two classes of voltage-dependent calcium channels of single vascular smooth muscle cells in short-term primary culture

P. Pacaud, J. Mironneau, C. Mironneau, 1987, Pflügers Archiv - European Journal of Physiology.

Noradrenaline activates acalcium-activate d chloride conductance andincreases thevoltage-dependent calcium current incultured single cells ofratportal

P. Pacaud, J. Mironneau, C. Mironneau, 1989 .

Muscle Cells

P. Pacaud, A. Baron, J. Mironneau, 2005 .

Mechanism of the ATP-induced rise in cytosolic Ca2+ in freshly isolated smooth muscle cells from human saphenous vein

P. Pacaud, G. Loirand, 1995, Pflügers Archiv.

Increased β2-adrenergic vasorelaxation at the early phase of endotoxemic shock in rats.

B. Rozec, Y. Blanloeil, C. Gauthier, 2015, Vascular pharmacology.

Rise in cytosolic Ca2+ concentration induced by P2‐purinoceptor activation in isolated myocytes from the rat gastrointestinal tract

H. Blottière, P. Pacaud, G. Loirand, 1996, British journal of pharmacology.

Rho kinase blockade prevents inflammation via nuclear factor kappa B inhibition: evidence in Crohn's disease and experimental colitis.

J. Galmiche, P. Pacaud, A. Bourreille, 2003, Gastroenterology.

RhoA Phosphorylation Induces Rac1 Release from Guanine Dissociation Inhibitor α and Stimulation of Vascular Smooth Muscle Cell Migration

P. Pacaud, M. Rolli-Derkinderen, G. Loirand, 2010, Molecular and Cellular Biology.

The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure

R. Torres, P. Pacaud, D. Henrion, 2010, Nature Medicine.

Small G proteins in the cardiovascular system: physiological and pathological aspects.

P. Pacaud, V. Sauzeau, G. Loirand, 2013, Physiological reviews.

Shear Stress Regulates Endothelial Microparticle Release

G. Chironi, A. Tedgui, X. Loyer, 2013, Circulation research.

Location of intracranial aneurysms is the main factor associated with rupture in the ICAN population

R. Redon, P. Bijlenga, J. Desilles, 2020, Journal of Neurology, Neurosurgery, and Psychiatry.

P. Pacaud, P. Chardin, G. Loirand, 1999, The Journal of physiology.

Phosphorylation of Serine 188 Protects RhoA from Ubiquitin/Proteasome-Mediated Degradation in Vascular Smooth Muscle Cells

P. Pacaud, D. Henrion, E. Lemichez, 2005, Circulation research.

Rho kinases in cardiovascular physiology and pathophysiology.

P. Pacaud, P. Guérin, G. Loirand, 2006, Circulation research.

Angiotensin II induces RhoA activation through SHP2-dependent dephosphorylation of the RhoGAP p190A in vascular smooth muscle cells.

P. Pacaud, J. Brégéon, M. Rolli-Derkinderen, 2009, American journal of physiology. Cell physiology.

Angiotensin II induces RhoA activation through SHP 2-dependent dephosphorylation of the RhoGAP p 190 A in vascular smooth muscle cells

P. Pacaud, J. Brégéon, M. Rolli-Derkinderen, 2009 .

Rare coding variants in CTSO, a potential new actor of arterial remodeling, are associated to familial intracranial aneurysm

R. Redon, C. Dina, S. Chatel, 2023, medRxiv.

Characterization of 3D bifurcations in micro-scan and MRA-TOF images of cerebral vasculature for prediction of intra-cranial aneurysms

A Nouri, F Autrusseau, R Bourcier, 2020, Comput. Medical Imaging Graph..

3D bifurcations characterization for intra-cranial aneurysms prediction

Alban Gaignard, Florent Autrusseau, Richard Redon, 2019, Medical Imaging: Image Processing.

Rare Coding Variants in ANGPTL6 Are Associated with Familial Forms of Intracranial Aneurysm.

R. Redon, E. Génin, C. Dina, 2018, American journal of human genetics.

The role of Rho protein signaling in hypertension

P. Pacaud, G. Loirand, 2010, Nature Reviews Cardiology.

OP-EHEA190316_online 3081..3094

R. Redon, C. Dina, Céline Marionneau, 2021 .

Regulation of Rho signaling pathways in interleukin‐2‐stimulated human T‐lymphocytes

J. Bertoglio, P. Pacaud, C. Thibault, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The Rho protein exchange factor Vav3 regulates vascular smooth muscle cell proliferation and migration.

P. Pacaud, D. Ferland-McCollough, G. Loirand, 2010, Cardiovascular research.

Cyclic GMP-dependent Protein Kinase Signaling Pathway Inhibits RhoA-induced Ca2+ Sensitization of Contraction in Vascular Smooth Muscle*

S. Lohmann, J. Bertoglio, P. Pacaud, 2000, The Journal of Biological Chemistry.

Transglutaminase-dependent RhoA Activation and Depletion by Serotonin in Vascular Smooth Muscle Cells*

G. Melino, P. Pacaud, P. Tharaux, 2007, Journal of Biological Chemistry.

Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension

P. Pacaud, C. Sagan, M. Rolli-Derkinderen, 2005, British journal of pharmacology.

Rho Kinases in Health and Disease: From Basic Science to Translational Research

G. Loirand, 2015, Pharmacological Reviews.

RhoA Expression Is Controlled by Nitric Oxide through cGMP-dependent Protein Kinase Activation*

Céline Marionneau, P. Pacaud, M. Rolli-Derkinderen, 2003, The Journal of Biological Chemistry.

Involvement of Rho GTPases and their regulators in the pathogenesis of hypertension

P. Pacaud, G. Loirand, 2014, Small GTPases.

Neointimal Hyperplasia after Stenting in a Human Mammary Artery Organ Culture

M. Heymann, P. Pacaud, G. Grimandi, 2004, Journal of Vascular Research.

Hyaluronan induces vascular smooth muscle cell migration through RHAMM-mediated PI3K-dependent Rac activation.

P. Pacaud, Y. Gouëffic, C. Guilluy, 2006, Cardiovascular research.

Cardiac Protective Effects of Moringa oleifera Seeds in Spontaneous Hypertensive Rats.

P. Pacaud, A. Tesse, S. Derbré, 2016, American journal of hypertension.

Expression of sialyl-Tn epitopes on β1 integrin alters epithelial cell phenotype, proliferation and haptotaxis

J. Le Pendu, M. Clément, G. Loirand, 2004, Journal of Cell Science.

Structural Design and Analysis of the RHOA-ARHGEF1 Binding Mode: Challenges and Applications for Protein-Protein Interface Prediction

B. Offmann, S. Téletchéa, G. Loirand, 2021, Frontiers in Molecular Biosciences.

Benefit of Mineralocorticoid Receptor Antagonism in AKI: Role of Vascular Smooth Muscle Rac1.

S. Lechner, F. Jaisser, A. Nguyen Dinh Cat, 2017, Journal of the American Society of Nephrology : JASN.

Rac1 as a therapeutic anticancer target: promises and limitations.

C. Bailly, V. Sauzeau, G. Loirand, 2022, Biochemical pharmacology.

Essential role of smooth muscle Rac1 in severe asthma-associated airway remodelling

A. Magnan, G. Bouchaud, M. Pretolani, 2021, Thorax.

Targeting PI3Kγ activity decreases vascular trauma-induced intimal hyperplasia through modulation of the Th1 response

E. Hirsch, A. Saoudi, M. Wymann, 2014, The Journal of experimental medicine.

Modulation of RhoA—Rho kinase‐mediated Ca2+ sensitization of rabbit myometrium during pregnancy — role of Rnd3

P. Pacaud, P. Chardin, V. Sauzeau, 2003, The Journal of physiology.

Evidence for two distinct calcium channels in rat vascular smooth muscle cells in short-term primary culture

P. Pacaud, J. Mironneau, C. Mironneau, 1986, Pflügers Archiv.

Desmethoxyverapamil-sensitive calcium channels in rat portal vein smooth muscle.

P. Pacaud, C. Dacquet, J. Mironneau, 1989, European journal of pharmacology.

Why Are Women Predisposed to Intracranial Aneurysm?

Anne-Clémence Vion, G. Loirand, Céline Baron‐Menguy, 2022, Frontiers in Cardiovascular Medicine.

Structure–Activity Relationships of Human Urotensin II and Related Analogues on Rat Aortic Ring Contraction

Pierre Renard, Jérôme Leprince, Hubert Vaudry, 2003, Journal of enzyme inhibition and medicinal chemistry.

Comparison of binding affinities and calcium current inhibitory effects of a 1,4-dihydropyridine derivative (PN 200-110) in vascular smooth muscle.

P. Pacaud, C. Dacquet, J. Mironneau, 1988, Biochemical and biophysical research communications.

Synthesis and Pharmacological Study of Rho-Kinase Inhibitors: Pharmacomodulations on the Lead Compound Fasudil

M. Luyckx, P. Pacaud, B. Gressier, 2003, Journal of enzyme inhibition and medicinal chemistry.

Rho exchange factors in the cardiovascular system.

P. Pacaud, E. Scalbert, G. Loirand, 2008, Current opinion in pharmacology.

Intracellular cations modulate noradrenaline‐stimulated calcium entry into smooth muscle cells of rat portal vein.

P. Pacaud, J. Mironneau, C. Mironneau, 1992, The Journal of physiology.

(+)−[3H]‐PN 200–110 binding to cell membranes and intact strips of portal vein smooth muscle: characterization and modulation by membrane potential and divalent cations

C. Dacquet, J. Mironneau, C. Mironneau, 1989, British journal of pharmacology.

Angiotensin II Activates the RhoA Exchange Factor Arhgef1 in Humans

X. Jeunemaître, P. Pacaud, M. Azizi, 2015, Hypertension.

RhoA guanine exchange factor expression profile in arteries: evidence for a Rho kinase-dependent negative feedback in angiotensin II-dependent hypertension.

P. Pacaud, D. Ferland-McCollough, A. Bril, 2012, American journal of physiology. Cell physiology.

feedback in angiotensin II-dependent hypertension arteries: evidence for a Rho kinase-dependent negative RhoA guanine exchange factor expression profile in

D. Ferland-McCollough, A. Bril, G. Chadeuf, 2016 .

Prime role of IL-17A in neutrophilia and airway smooth muscle contraction in a house dust mite-induced allergic asthma model.

A. Magnan, S. Brouard, F. Braza, 2015, The Journal of allergy and clinical immunology.

Stent Implantation Activates RhoA in Human Arteries: Inhibitory Effect of Rapamycin

P. Pacaud, M. Rolli-Derkinderen, V. Sauzeau, 2005, Journal of Vascular Research.

Regulation of Rho proteins by phosphorylation in the cardiovascular system.

P. Pacaud, C. Guilluy, G. Loirand, 2006, Trends in cardiovascular medicine.

Release of Ca2+ from intracellular store in smooth muscle cells of rat portal vein by ATP‐induced Ca2+ entry

P. Pacaud, G. Loirand, Guillaume Grëgoire, 1994, British journal of pharmacology.

Direct stenting limits sirolimus-eluting stent edge neointimal thickening.

M. Heymann, P. Pacaud, Y. Gouëffic, 2007, Journal of vascular surgery.

Prediction of Unruptured Intracranial Aneurysm Evolution: The UCAN Project.

R. Redon, O. Naggara, F. Autrusseau, 2020, Neurosurgery.

SUN2 regulates mitotic duration in response to extracellular matrix rigidity

C. Guilluy, G. Chadeuf, L. Lafanechère, 2022, Proceedings of the National Academy of Sciences of the United States of America.

RhoA and resistance artery remodeling.

P. Pacaud, M. Rolli-Derkinderen, G. Loirand, 2005, American journal of physiology. Heart and circulatory physiology.

Sildenafil Prevents Change in RhoA Expression Induced by Chronic Hypoxia in Rat Pulmonary Artery

P. Pacaud, S. Lehoux, M. Rolli-Derkinderen, 2003, Circulation research.

8TH INTERNATIONAL SYMPOSIUM ON RESISTANCE ARTERIES New Developments in Resistance Artery Research: From Molecular Biology to Bedside RhoA and resistance artery remodeling

P. Pacaud, M. Rolli-Derkinderen, G. Loirand, 2005 .

RhoA activation and interaction with Caveolin-1 are critical for pressure-induced myogenic tone in rat mesenteric resistance arteries.

J. Balligand, B. Lévy, P. Pacaud, 2007, Cardiovascular research.

Moringa oleifera Seeds Attenuate Vascular Oxidative and Nitrosative Stresses in Spontaneously Hypertensive Rats

P. Pacaud, A. Tesse, G. Loirand, 2017, Oxidative medicine and cellular longevity.

P2Y(1), P2Y(2), P2Y(4), and P2Y(6) receptors are coupled to Rho and Rho kinase activation in vascular myocytes.

P. Pacaud, C. Desgranges, A. Gadeau, 2000, American journal of physiology. Heart and circulatory physiology.

DualEffect ofThrombin on Voltage-Dependent Ca21Channels ofPortal VeinSmooth MuscleCells

P. Pacaud, A. Baron, C. Mironneau, 1993 .

Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis

R. Torres, X. Prieur, L. Castan, 2017, The Journal of clinical investigation.

Non‐genomic inhibition of human P2X7 purinoceptor by 17β‐oestradiol

P. Pacaud, L. Ferrier, G. Loirand, 1998, The Journal of physiology.

PPADS inhibits P2Y1 purinoceptors in rat brain capillary endothelial cells and in rat ileal myocytes by an indirect mechanism.

P. Pacaud, P. Vigne, C. Frelin, 1998, Biochemical and biophysical research communications.

Calcium-activated chloride current in rat vascular smooth muscle cells in short-term primary culture

P. Pacaud, J. Mironneau, C. Mironneau, 1989, Pflügers Archiv - European Journal of Physiology.

Allergic Sensitization Driving Immune Phenotyping and Disease Severity in a Mouse Model of Asthma

E. Delage, A. Magnan, G. Bouchaud, 2023, Allergy, asthma & immunology research.

Involvement of Rho GTPases and their regulators in the pathogenesis of hypertension.

P. Pacaud, G. Loirand, 2014, Small GTPases.

Electrografting of a biodegradable layer as a primer adhesion coating onto a metallic stent: in vitro and in vivo evaluations

V. Langlois, E. Renard, Aymeric Seron, 2013, Journal of Materials Science: Materials in Medicine.

Small G proteins in the cardiovascular system: physiological and pathological aspects.

P. Pacaud, V. Sauzeau, G. Loirand, 2013, Physiological reviews.

The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure

R. Torres, P. Pacaud, D. Henrion, 2010, Nature Medicine.

[New protagonists in asthma pathophysiology].

A. Magnan, G. Bouchaud, A. Magnan, 2019, Presse medicale.

AMPK Alpha 1-Induced RhoA Phosphorylation Mediates Vasoprotective Effect of Estradiol

B. Viollet, P. Pacaud, D. Henrion, 2011, Arteriosclerosis, thrombosis, and vascular biology.

RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome.

R. Redon, E. Génin, C. Dina, 2019, European heart journal.

WNK1 Regulates Vasoconstriction and Blood Pressure Response to &agr;1-Adrenergic Stimulation in Mice

S. Faure, X. Jeunemaître, J. Achard, 2011, Hypertension.

P. Pacaud, M. Rolli-Derkinderen, C. Guilluy, 2008 .

Pharmacological block of Ca2+-activated Cl− current in rat vascular smooth muscle cells in short-term primary culture

P. Pacaud, A. Baron, J. Mironneau, 1991, Pflügers Archiv.

Effect of extracellular ATP on cytosolic Ca2+ concentration in rat pulmonary artery myocytes.

R. Marthan, P. Pacaud, C. Guibert, 1996, The American journal of physiology.

[A new pathophysiological element in severe asthma: GTPase Rac].

V. Sauzeau, G. Loirand, D. Hassoun, 2022, Revue des maladies respiratoires.

Angiotensin II induces RhoA activation through SHP2-dependent dephosphorylation of the RhoGAP p190A in vascular smooth muscle cells.

P. Pacaud, J. Brégéon, M. Rolli-Derkinderen, 2009, American journal of physiology. Cell physiology.

Calcium-activated cation channel in rat portal vein myocytes.

P. Pacaud, A. Baron, J. Mironneau, 1991, Zeitschrift fur Kardiologie.