Takashi Ito

发表

Progression of coronary atherosclerosis relates to the onset of myocardial infarction in an animal model of spontaneous myocardial infarction (WHHLMI rabbits).

M. Shiomi, Takashi Ito, S. Yamada, 2004, Experimental animals.

Cholesterol-fed ovariectomized monkeys are good animal models for human atherosclerosis of postmenopausal women

R. Torii, M. Shiomi, Y. Eguchi, 2003, Primates.

Contribution of the WHHL rabbit, an animal model of familial hypercholesterolemia, to elucidation of the anti-atherosclerotic effects of statins.

M. Shiomi, T. Koike, Takashi Ito, 2013, Atherosclerosis.

Myocardial Infarction-Prone Watanabe Heritable Hyperlipidemic Rabbits with Mesenteric Fat Accumulation Are a Novel Animal Model for Metabolic Syndrome

Tsutomu Kobayashi, M. Shiomi, Takashi Ito, 2012, Pathobiology.

Atheroma stabilizing effects of simvastatin due to depression of macrophages or lipid accumulation in the atheromatous plaques of coronary plaque-prone WHHL rabbits.

M. Shiomi, Takashi Ito, S. Yamada, 2005, Atherosclerosis.

Discrimination of recent ischemic myocardial changes in WHHLMI rabbits from the findings of postmortem degeneration.

M. Shiomi, Takashi Ito, S. Yamada, 2005, Experimental animals.

Novel insights into coronary lumen preservation during progression of coronary atherosclerosis in coronary atherosclerosis-prone rabbits

Katsuya Yoshida, K. Gould, M. Shiomi, 2004, Coronary artery disease.

Invasion of atheromatous plaques into tunica media causes coronary outward remodeling in WHHLMI rabbits.

A. Matsukawa, H. Itabe, M. Shiomi, 2008, Atherosclerosis.

Vasospasm of Atherosclerotic Coronary Arteries Precipitates Acute Ischemic Myocardial Damage in Myocardial Infarction–Prone Strain of the Watanabe Heritable Hyperlipidemic Rabbits

P. Libby, N. Nitta, K. Murata, 2013, Arteriosclerosis, thrombosis, and vascular biology.

M. Shiomi, Takashi Ito, S. Yamada, 2004, Experimental animals.

Decreased arterial responses in WHHL rabbits, an animal model of spontaneous hypercholesterolemia and atherosclerosis.

Y. Ueno, M. Shiomi, J. Adachi, 2002, Experimental animals.

Combination treatment with an insulin action enhancer and an inhibitor of HMG-CoA reductase shows a synergistic effect on atherosclerosis of WHHL rabbits

H. Horikoshi, Y. Tsujita, M. Shiomi, 2000 .

Electrocardiograms corresponding to the development of myocardial infarction in anesthetized WHHLMI rabbits (Oryctolagus cuniculus), an animal model for familial hypercholesterolemia.

Tsutomu Kobayashi, M. Shiomi, Takashi Ito, 2012, Comparative medicine.

The Watanabe heritable hyperlipidemic (WHHL) rabbit, its characteristics and history of development: a tribute to the late Dr. Yoshio Watanabe.

Masashi Shiomi, M. Shiomi, Takashi Ito, 2009, Atherosclerosis.

Roles of the WHHL Rabbit in Translational Research on Hypercholesterolemia and Cardiovascular Diseases

Masashi Shiomi, Tsutomu Kobayashi, M. Shiomi, 2011, Journal of biomedicine & biotechnology.

Effect of cerivastatin sodium, a new inhibitor of HMG‐CoA reductase, on plasma lipid levels, progression of atherosclerosis, and the lesional composition in the plaques of WHHL rabbits

M. Shiomi, Takashi Ito, 1999, British journal of pharmacology.

Development of an animal model for spontaneous myocardial infarction (WHHLMI rabbit).

Jianglin Fan, Masashi Shiomi, Jianglin Fan, 2003, Arteriosclerosis, thrombosis, and vascular biology.

Correlation of vulnerable coronary plaques to sudden cardiac events. Lessons from a myocardial infarction-prone animal model (the WHHLMI rabbit).

Jianglin Fan, Masashi Shiomi, Jianglin Fan, 2004, Journal of atherosclerosis and thrombosis.

Development of an Animal Model for Spontaneous Myocardial Infarction (WHHLMI Rabbit)

Jianglin Fan, M. Shiomi, S. Kawashima, 2003 .

Stability of Atheromatous Plaque Affected by Lesional Composition

M. Shiomi, T. Ito, Y. Hirouchi, 2001, Annals of the New York Academy of Sciences.

The effect of selective breeding on the development of coronary atherosclerosis in WHHL rabbits. An animal model for familial hypercholesterolemia.

Y. Watanabe, M. Shiomi, T. Ito, 1985, Atherosclerosis.

Cell compositions of coronary and aortic atherosclerotic lesions in WHHL rabbits differ. An immunohistochemical study.

M. Shiomi, T. Ito, M. Ueda, 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.

Inheritability of atherosclerosis and the role of lipoproteins as risk factors in the development of atherosclerosis in WHHL rabbits: risk factors related to coronary atherosclerosis are different from those related to aortic atherosclerosis.

Y. Watanabe, M. Shiomi, T. Ito, 1992, Atherosclerosis.

Immunohistochemical and quantitative analysis of cellular and extracellular components of aortic atherosclerosis in WHHL rabbits.

M. Ueda, Takashi Ito, T. Tsukada, 1994, Journal of atherosclerosis and thrombosis.

Age-associated decrease in plasma cholesterol and changes in cholesterol metabolism in homozygous Watanabe heritable hyperlipidemic rabbits.

Y. Tsujita, M. Shiomi, T. Ito, 2000, Metabolism: clinical and experimental.

Reduction of serum cholesterol levels alters lesional composition of atherosclerotic plaques. Effect of pravastatin sodium on atherosclerosis in mature WHHL rabbits.

Y. Tsujita, Y. Watanabe, M. Shiomi, 1995, Arteriosclerosis, thrombosis, and vascular biology.

Pravastatin sodium, a competitive inhibitor of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase, decreases the cholesterol content of newly secreted very-low-density lipoprotein in Watanabe heritable hyperlipidemic rabbits.

M. Shiomi, T. Ito, Takashi Ito, 1994, Metabolism: clinical and experimental.

MTP inhibitor decreases plasma cholesterol levels in LDL receptor-deficient WHHL rabbits by lowering the VLDL secretion.

M. Shiomi, T. Ito, Takashi Ito, 2001, European journal of pharmacology.

Cerebral atherosclerosis occurs spontaneously in homozygous WHHL rabbits.

M. Shiomi, T. Ito, Takashi Ito, 2001, Atherosclerosis.

Combination treatment with troglitazone, an insulin action enhancer, and pravastatin, an inhibitor of HMG-CoA reductase, shows a synergistic effect on atherosclerosis of WHHL rabbits.

H. Horikoshi, Y. Tsujita, M. Shiomi, 1999, Atherosclerosis.

Suppression of established atherosclerosis and xanthomas in mature WHHL rabbits by keeping their serum cholesterol levels extremely low. Effect of pravastatin sodium in combination with cholestyramine.

Y. Tsujita, M. Kuroda, M. Arai, 1990, Atherosclerosis.

Lapaquistat acetate, a squalene synthase inhibitor, changes macrophage/lipid‐rich coronary plaques of hypercholesterolaemic rabbits into fibrous lesions

M Shiomi, M. Shiomi, T. Ito, 2008, British journal of pharmacology.