C. Ellis

发表

Synthesis and evaluation of unsaturated caprolactams as interleukin-1beta converting enzyme (ICE) inhibitors.

Richard L. C. Wang, W. Lu, Yili Wang, 2007, Bioorganic & medicinal chemistry.

Synthesis and evaluation of thiazepines as interleukin-1beta converting enzyme (ICE) inhibitors.

Richard L. C. Wang, W. Lu, Yili Wang, 2006, Bioorganic & medicinal chemistry letters.

Discovery of novel conformationally restricted diazocan peptidomimetics as inhibitors of interleukin-1beta synthesis.

Richard L. C. Wang, W. Lu, Yili Wang, 2005, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of tricyclic pyrrolopyrimidinones as dipeptide mimetics: Inhibition of interleukin-1β-converting enzyme

Richard L. C. Wang, Yili Wang, W. Lu, 2005 .

Design, synthesis, and evaluation of orally active 4-(2,4-difluoro-5-(methoxycarbamoyl)phenylamino)pyrrolo[2,1-f][1,2,4]triazines as dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 inhibitors.

J. Fargnoli, J. Barrish, J. Tokarski, 2005, Journal of medicinal chemistry.

Synthesis and evaluation of novel 1-(2-acylhydrazinocarbonyl)-cycloalkyl carboxamides as interleukin-1beta converting enzyme (ICE) inhibitors.

Richard L. C. Wang, W. Lu, Yili Wang, 2006, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of novel 8,6-fused bicyclic peptidomimetic compounds as interleukin-1β converting enzyme inhibitors

Richard L. C. Wang, Yili Wang, W. Lu, 2005 .

1-[3-Aminobenzisoxazol-5'-yl]-3-trifluoromethyl-6-[2'-(3-(R)-hydroxy-N-pyrrolidinyl)methyl-[1,1']-biphen-4-yl]-1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-one (BMS-740808) a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa.

P. Lam, K. He, R. Knabb, 2006, Bioorganic & medicinal chemistry letters.

Biaryl substituted alkylboronate esters as thrombin inhibitors

J. Wityak, P. Weber, C. Dominguez, 1997 .

Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 1.

J R Pruitt, R. Knabb, R. Wexler, 1999, Journal of medicinal chemistry.

Discovery of 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-N-[2-fluoro-4- [(2'-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide hydrochloride (razaxaban), a highly potent, selective, and orally bioavailable factor Xa inhibitor.

P. Lam, R. Knabb, R. Alexander, 2005, Journal of medicinal chemistry.

Nonbenzamidine tetrazole derivatives as factor Xa inhibitors.

P. Lam, R. Knabb, R. Alexander, 2003, Bioorganic & medicinal chemistry letters.

Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 2.

R. Knabb, R. Alexander, R. Wexler, 1999, Journal of Medicinal Chemistry.

Nonbenzamidine isoxazoline derivatives as factor Xa inhibitors.

P. Lam, R. Knabb, R. Wexler, 1997, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of 4-(3-hydroxyphenylamino)pyrrolo[2,1-f][1,2,4]triazine based VEGFR-2 kinase inhibitors.

J. Fargnoli, J. Tokarski, J. Hunt, 2005, Bioorganic & medicinal chemistry letters.

Design, structure-activity relationship, and pharmacokinetic profile of pyrazole-based indoline factor Xa inhibitors.

P. Lam, K. He, R. Knabb, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of novel 8,5-fused bicyclic peptidomimetic compounds as interleukin-1beta converting enzyme (ICE) inhibitors.

Richard L. C. Wang, W. Lu, Yili Wang, 2006, Bioorganic & medicinal chemistry.

Synthesis and Evaluation of Thiazepines as Interleukin-1β Converting Enzyme (ICE) Inhibitors.

C. Ellis, 2006 .

Balanced angiotensin II receptor antagonists. I. The effects of biphenyl “ortho”-substitution on AT1/AT2 affinities

P. Timmermans, R. Olson, R. Wexler, 1994 .