V. Kysil

发表

Screening for Caspase-3 Inhibitors: A New Class of Potent Small-Molecule Inhibitors of Caspase-3

Alexey P. Ilyin, L. Sklar, E. Prossnitz, 2006, Journal of biomolecular screening.

Multicomponent approach to unique 1,4-diazepine-2-amines

S. Tkachenko, A. Khvat, V. Kysil, 2009 .

Antagonists of 5-HT₆ receptors. Substituted 3-(phenylsulfonyl)pyrazolo[1,5-a]pyrido[3,4-e]pyrimidines and 3-(phenylsulfonyl)pyrazolo[1,5-a]pyrido[4,3-d]pyrimidines-Synthesis and 'structure-activity' relationship.

I. Okun, M. Kadieva, V. Kysil, 2012, Bioorganic & medicinal chemistry letters.

Complexity-enhancing acid-promoted rearrangement of tricyclic products of tandem Ugi 4CC/intramolecular Diels-Alder reaction.

Mikhail Krasavin, Volodymyr Kysil, Alexandre V Ivachtchenko, 2006, The Journal of organic chemistry.

General Multicomponent Strategy for the Synthesis of 2‐Amino‐1,4‐diazaheterocycles: Scope, Limitations, and Utility

S. Tkachenko, Caroline T Williams, A. Khvat, 2010 .

Poorly reactive 5-piperazin-1-yl-1,3,4-thiadiazol-2-amines rendered as valid substrates for Groebke–Blackburn type multi-component reaction with aldehydes and isocyanides using TMSCl as a promoter

Mikhail Nikulnikov, Mikhail Krasavin, Sergey Tsirulnikov, 2008 .

One-pot tandem complexity-generating reaction based on Ugi four component condensation and intramolecular cyclization

Alexey P. Ilyin, V. Kysil, A. Ivachtchenko, 2007 .

Multi-Component Reactions in Heterocyclic Chemistry

R. R. Khairullina, I. V. Paramonov, Alexey P. Ilyn, 2011 .

Streamlined access to 2,3-dihydropyrazino[1,2-a]indole-1,4-diones via Ugi reaction followed by microwave-assisted cyclization

M. Krasavin, V. Kysil, A. Ivachtchenko, 2009 .

Synthesis and structure-activity relationship (SAR) of (5,7-disubstituted 3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidin-2-yl)-methylamines as potent serotonin 5-HT(6) receptor (5-HT(6)R) antagonists.

S. Tkachenko, I. Okun, M. Kadieva, 2011, Journal of medicinal chemistry.

(3-Phenylsulfonylcycloalkano[e and d]pyrazolo[1,5-a]pyrimidin-2-yl)amines: potent and selective antagonists of the serotonin 5-HT6 receptor.

S. Tkachenko, I. Okun, M. Kadieva, 2010, Journal of medicinal chemistry.

TMSCl-promoted isocyanide-based MCR of ethylenediamines: an efficient assembling of 2-aminopyrazine core

S. Tkachenko, Caroline T Williams, A. Khvat, 2007 .

Synthesis of cycloalkane-annelated 3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidines and their evaluation as 5-HT6 receptor antagonists.

S. Tkachenko, I. Okun, M. Kadieva, 2010, Bioorganic & medicinal chemistry letters.

Streamlined Access to 2,3‐Dihydropyrazino[1,2‐a]indole‐1,4‐diones via Ugi Reaction Followed by Microwave‐Assisted Cyclization.

M. Krasavin, V. Kysil, A. Ivachtchenko, 2010 .

Antagonists of serotonin 5-HT6 receptors. III. Pyridine-substituted 3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidines: synthesis and structure – activity relationship

I. Okun, M. Kadieva, V. Kysil, 2012, Pharmaceutical Chemistry Journal.

Synthesis and Structure−Activity Relationship of 4-Substituted 2-(2-Acetyloxyethyl)-8-(morpholine- 4-sulfonyl)pyrrolo[3,4-c]quinoline- 1,3-diones as Potent Caspase-3 Inhibitors

K. Balakin, S. Tkachenko, I. Okun, 2005 .

Synthesis and Biological Evaluation of Novel 5,8‐Disubstituted‐2‐methyl‐2,3,4,5‐tetrahydro‐1H‐pyrido[4,3‐b] indoles as 5‐HT6 and H1 Receptors Antagonists

S. Tkachenko, E. Frolov, A. Khvat, 2009, Archiv der Pharmazie.

Pyrrolo[3,4-c]Quinoline-1,3-Diones as Potent Caspase-3 Inhibitors: Synthesis and SAR of 8-Sulfamoyl-1,3-Dioxo-2,3-Dihydro-1H-Pyrrolo[3,4- c]Quinolines

S. Tkachenko, I. Okun, D. Kravchenko, 2006 .

Pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors. Synthesis and SAR of 2-substituted 4-methyl-8-(morpholine-4-sulfonyl)-pyrrolo[3,4-c]quinoline-1,3-diones.

S. Tkachenko, I. Okun, D. Kravchenko, 2005, European journal of medicinal chemistry.

Screening for Caspase-3 Inhibitors: Effect of a Reducing Agent on Identified Hit Chemotypes

S. Tkachenko, I. Okun, S. Malarchuk, 2006, Journal of biomolecular screening.

Synthesis and caspase-3 inhibitory activity of 8-sulfonyl-1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]quinolines.

S. Tkachenko, I. Okun, D. Kravchenko, 2005, Farmaco.

Synthesis and SAR of 3-arylsulfonyl-pyrazolo[1,5-a]pyrimidines as potent serotonin 5-HT6 receptor antagonists.

S. Tkachenko, I. Okun, M. Kadieva, 2011, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of novel gamma-carboline analogues of Dimebon as potent 5-HT6 receptor antagonists.

S. Tkachenko, I. Okun, E. Frolov, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and caspase-3 inhibitory activity of 8-sulfonyl-1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]quinolines.

S. Tkachenko, I. Okun, D. Kravchenko, 2005, Farmaco.

8-Sulfonyl-substituted tetrahydro-1H-pyrido[4,3-b]indoles as 5-HT6 receptor antagonists.

S. Tkachenko, I. Okun, V. Kysil, 2010, European journal of medicinal chemistry.

Synthesis and receptor activity of 2-substituted 8-methyl-5-(2-pyridinylethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles

I. Okun, V. Kysil, A. Ivachtchenko, 2013, Pharmaceutical Chemistry Journal.

Microwave-mediated reactions of 3-aminomethylpyridines with acetylenedicarboxylates. A novel synthetic route to dihydronaphthyridines and naphthyridine-1-ones

A. Kiselyov, Y. Ivanov, Caroline T Williams, 2005 .

Microwave‐Mediated Reactions of 3‐Aminomethylpyridines with Acetylenedicarboxylates. A Novel Synthetic Route to Dihydronaphthyridines and Naphthyridine‐1‐ones.

A. Kiselyov, Y. Ivanov, Caroline T Williams, 2005 .

2-Substituted 5,6-dimethyl-3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidines: new series of highly potent and specific serotonin 5-HT6 receptor antagonists.

S. Tkachenko, I. Okun, M. Kadieva, 2011, European journal of medicinal chemistry.

Trimethylsilyl Chloride as a Promoter for the Groebke–Blackburn Reaction: Preparation of Imidazo[2,1-b][1,3]Benzothiazoles

M. Krasavin, V. Kysil, A. Ivachtchenko, 2009 .