C. Bauer

发表

The Interleukin-1β-Converting Enzyme Inhibitor Pralnacasan Reduces Dextran Sulfate Sodium-Induced Murine Colitis and T Helper 1 T-Cell Activation

H. Lehr, S. Endres, B. Siegmund, 2004, Journal of Pharmacology and Experimental Therapeutics.

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

J. Tschopp, H. Lehr, E. Latz, 2010, Gut.

Strategies to relieve immunosuppression in pancreatic cancer.

K. Lauber, S. Endres, S. Rothenfusser, 2015, Immunotherapy.

The Specific Type-4 Phosphodiesterase Inhibitor Mesopram Alleviates Experimental Colitis in Mice

H. Lehr, S. Endres, F. Rieder, 2003, Journal of Pharmacology and Experimental Therapeutics.

Chemosensitization of Pancreatic Carcinoma Cells to Enhance T Cell-Mediated Cytotoxicity Induced by Tumor Lysate-Pulsed Dendritic Cells

S. Endres, M. Schnurr, A. Eigler, 2005, Journal of immunotherapy.

Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer

T. Gress, M. Huber, H. Raifer, 2021, Nature Communications.

Pralnacasan improves experimental murine colitis JPET # 57059 1 The ICE inhibitor pralnacasan reduces dextran sulfate sodium-induced murine colitis and Th 1 T-cell activation

H. Lehr, S. Endres, B. Siegmund, 2003 .

FastDC derived from human monocytes within 48 h effectively prime tumor antigen-specific cytotoxic T cells.

S. Endres, A. Eigler, C. Bauer, 2005, Journal of immunological methods.

Combined use of toll-like receptor agonists and prostaglandin E(2) in the FastDC model: rapid generation of human monocyte-derived dendritic cells capable of migration and IL-12p70 production.

S. Endres, M. Schnurr, A. Eigler, 2008, Journal of immunological methods.

IFN‐α promotes definitive maturation of dendritic cells generated by short‐term culture of monocytes with GM‐CSF and IL‐4

S. Endres, M. Schnurr, A. Eigler, 2006 .

P10. Concomitant gemcitabine therapy negatively affects DC vaccine-induced CD8+ T cell and B cell responses but improves clinical efficacy in a murine pancreatic carcinoma model

F. Bauernfeind, P. Duewell, M. Schnurr, 2014, Journal of Immunotherapy for Cancer.

P10. Concomitant gemcitabine therapy negatively affects DC vaccine-induced CD8+ T cell and B cell responses but improves clinical efficacy in a murine pancreatic carcinoma model

S. Endres, C. Conrad, F. Bauernfeind, 2014, Journal of Immunotherapy for Cancer.

Single-cell RNA sequencing uncovers the nuclear decoy lincRNA PIRAT as a regulator of systemic monocyte immunity during COVID-19

Leon N. Schulte, C. Ruppert, A. Gruber, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Immunosuppressive βig-h3 links tumour stroma and dysfunctional T cells in pancreatic cancer

C. Bauer, 2018, Gut.

Dynamic Treg interactions with intratumoral APCs promote local CTL dysfunction.

Edward Y Kim, Edward Y. Kim, T. Mempel, 2014, The Journal of clinical investigation.

IL18 Receptor Signaling Inhibits Intratumoral CD8+ T-Cell Migration in a Murine Pancreatic Cancer Model

T. Gress, M. Buchholz, M. Huber, 2023, Cells.

IL-17A-producing CD8+ T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts

A. Waisman, Hyun-Dong Chang, R. Savai, 2023, Gut.

Stromal biology and therapy in pancreatic cancer: ready for clinical translation?

D. Tuveson, T. Gress, M. Buchholz, 2018, Gut.

The Immune Microenvironment in Pancreatic Cancer

T. Gress, M. Buchholz, M. Huber, 2020, International journal of molecular sciences.

Prevailing over T cell exhaustion: New developments in the immunotherapy of pancreatic cancer.

S. Ormanns, T. Gress, P. Duewell, 2016, Cancer letters.

Intravital imaging of CD8+ T cell function in cancer

T. Mempel, C. Bauer, 2008, Clinical & Experimental Metastasis.

Single cell RNA-seq uncovers the nuclear decoy lincRNA PIRAT as a regulator of systemic monocyte immunity during COVID-19

Leon N. Schulte, C. Ruppert, A. Gruber, 2021 .

IL-18 But Not IL-1 Signaling Is Pivotal for the Initiation of Liver Injury in Murine Non-Alcoholic Fatty Liver Disease

H. Zischka, L. Holdt, A. Gerbes, 2020, International journal of molecular sciences.

Dendritic cell-based vaccination of patients with advanced pancreatic carcinoma: results of a pilot study

T. Mussack, B. Emmerich, S. Endres, 2011, Cancer Immunology, Immunotherapy.

Proapoptotic and Antiapoptotic Proteins of the Bcl-2 Family Regulate Sensitivity of Pancreatic Cancer Cells Toward Gemcitabine and T-Cell–mediated Cytotoxicity

H. Lehr, S. Endres, E. Noessner, 2015, Journal of immunotherapy.

The ICE Inhibitor Pralnacasan Prevents DSS-Induced Colitis in C57BL/6 Mice and Suppresses IP-10 mRNA but Not TNF-α mRNA Expression

H. Lehr, S. Endres, A. Eigler, 2007, Digestive Diseases and Sciences.

Protective and Aggravating Effects of Nlrp3 Inflammasome Activation in IBD Models: Influence of Genetic and Environmental Factors

H. Lehr, S. Endres, P. Duewell, 2012, Digestive Diseases.

The interleukin-1 beta-converting enzyme inhibitor pralnacasan reduces dextran sulfate sodium-induced murine colitis and T helper 1 T-cell activation.

H. Lehr, S. Endres, B. Siegmund, 2004, The Journal of pharmacology and experimental therapeutics.

Nlrp3-dependent IL-1β inhibits CD103+ dendritic cell differentiation in the gut.

H. Lehr, S. Endres, T. Clavel, 2018, JCI insight.

The POLD1R689W variant increases the sensitivity of colorectal cancer cells to ATR and CHK1 inhibitors

T. Gress, M. Buchholz, E. Gallmeier, 2020, Scientific Reports.

Dendritic cell-based vaccination combined with gemcitabine increases survival in a murine pancreatic carcinoma model

H. Lehr, S. Endres, F. Bauernfeind, 2007, Gut.

The Combination of MiRNA-196b, LCN2, and TIMP1 is a Potential Set of Circulating Biomarkers for Screening Individuals at Risk for Familial Pancreatic Cancer

K. Strauch, G. Klöppel, D. Bartsch, 2018, Journal of clinical medicine.

An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma

S. Endres, E. Maraskovsky, F. Bauernfeind, 2011, International journal of cancer.

Microbial Monitoring For Biological Drug Substance Manufacturing: An Industry Perspective

R. Forng, C. Bauer, Michael Knight, 2015, PDA Journal of Pharmaceutical Science and Technology.

Refined strategies for the treatment of pancreatic carcinoma: targeting myeloid cells in order to overcome T cell exhaustion

C. Bauer, 2016, Gut.

The German National Case Collection for Familial Pancreatic Carcinoma (FaPaCa) / Knowledge Gained in 20 Years.

T. Gress, D. Bartsch, E. Matthäi, 2021, Deutsches Arzteblatt international.

IFN-alpha promotes definitive maturation of dendritic cells generated by short-term culture of monocytes with GM-CSF and IL-4.

S. Endres, M. Schnurr, A. Eigler, 2006, Journal of leukocyte biology.

Prevailing over T cell exhaustion: New developments in the immunotherapy of pancreatic cancer.

S. Ormanns, T. Gress, P. Duewell, 2016, Cancer letters.

Concomitant gemcitabine therapy negatively affects DC vaccine-induced CD8+ T-cell and B-cell responses but improves clinical efficacy in a murine pancreatic carcinoma model

F. Bauernfeind, P. Duewell, M. Schnurr, 2014, Cancer Immunology, Immunotherapy.

IL-18 receptor signaling regulates tumor-reactive CD8+ T-cell exhaustion via activation of the IL-2/STAT5/mTOR pathway in a pancreatic cancer model.

R. Savai, T. Gress, M. Buchholz, 2023, Cancer immunology research.