C. Froelich

发表

FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation.

J. Tschopp, M. Hahne, M. Irmler, 1998, Journal of immunology.

Apoptosis induced by granzyme B-glycosaminoglycan complexes: implications for granule-mediated apoptosis in vivo.

C. Hack, P. Seth, Baikun Wang, 1999, Journal of immunology.

Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly(ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment.

E. Alnemri, G. Salvesen, W. Earnshaw, 1996, Biochemical and biophysical research communications.

Extracellular activities of human granzymes. I. Granzyme A induces IL6 and IL8 production in fibroblast and epithelial cell lines.

L. Sower, G. Klimpel, C. Froelich, 1996, Cellular immunology.

Extracellular activities of human granzyme A. Monocyte activation by granzyme A versus alpha-thrombin.

L. Sower, N. Allegretto, G. Klimpel, 1996, Journal of immunology.

This information is current as Irradiation Chemotherapeutic Drugs , and Gamma Receptors But Not by Perforin / Granzyme B , FLIP Prevents Apoptosis Induced by Death

J. Tschopp, M. Hahne, M. Irmler, 1998 .

Rapid purification of cationic granule proteases: application to human granzymes.

D. Hudig, C. Froelich, U. Winkler, 1993, Protein expression and purification.

Extracellular granzymes A and B in humans: Detection of native species during CTL responses in vitro and in vivo

C. Hack, Jaap M Middeldorp, A. Wolbink, 1998, The Journal of Immunology.

Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis.

P. Seth, M. Pinkoski, K. Tomaselli, 1998, Blood.

Thrombin induces IL-6 production in fibroblasts and epithelial cells. Evidence for the involvement of the seven-transmembrane domain (STD) receptor for alpha-thrombin.

L. Sower, J. Fenton, G. Klimpel, 1995, Journal of immunology.

Human granzyme B degrades aggrecan proteoglycan in matrix synthesized by chondrocytes.

D. Hudig, C. Froelich, U. Winkler, 1993, Journal of immunology.

Purification and use of granzyme B.

A. Greenberg, L. Shi, C. Froelich, 2000, Methods in enzymology.

Human granzyme B is essential for DNA fragmentation of susceptible target cells

C. Froelich, B. Su, C. Froelich, 1994, European journal of immunology.

Synthesis and evaluation of diphenyl phosphonate esters as inhibitors of the trypsin-like granzymes A and K and mast cell tryptase.

U Winkler, D. Johnson, J. Powers, 1998, Journal of medicinal chemistry.

Lymphocyte granule-mediated apoptosis: matters of viral mimicry and deadly proteases.

V. Dixit, Xiaohe Yang, C. Froelich, 1998, Immunology today.

Human perforin: rapid enrichment by immobilized metal affinity chromatography (IMAC) for whole cell cytotoxicity assays.

C. Froelich, J. Turbov, W. Hanna, 1996, Biochemical and biophysical research communications.

HIV virions and HIV infection in vitro are unaffected by human granzymes A and B.

J. Lieberman, J. Levy, C. Mackewicz, 2000, AIDS research and human retroviruses.

Dominant chymotrypsin-like esterase activity in human lymphocyte granules is mediated by the serine carboxypeptidase called cathepsin A-like protective protein.

F. Tan, C. Froelich, H. Jackman, 1994, Journal of immunology.