Lin Chen

发表

Structure-activity relationship analysis of dammarane-type natural products as muscle-type creatine kinase activators.

Yao Cheng, Ruimei Li, Zixuan Lin, 2020, Bioorganic & medicinal chemistry letters.

Beneficial effects of benzodiazepine diazepam on chronic stress-induced impairment of hippocampal structural plasticity and depression-like behavior in mice

Jianguo Dai, Lin Chen, Yunan Zhao, 2012, Behavioural Brain Research.

Identification of Adenylate Kinase 5 as a Protein Target of Ginsenosides in Brain Tissues Using Mass Spectrometry-Based Drug Affinity Responsive Target Stability (DARTS) and Cellular Thermal Shift Assay (CETSA) Techniques.

Cai Lu, Ruimei Li, Feiyan Chen, 2022, Journal of agricultural and food chemistry.

A possible mechanism to the antidepressant-like effects of 20 (S)-protopanaxadiol based on its target protein 14-3-3 ζ

Yao Cheng, Ruimei Li, Feiyan Chen, 2021, Journal of ginseng research.

Identification and confirmation of 14-3-3 ζ as a novel target of ginsenosides in brain tissues

Jiapeng Zhu, Feiyan Chen, Zhu Zhu, 2020, Journal of ginseng research.

Preparation and quality assessment of high-purity ginseng total saponins by ion exchange resin combined with macroporous adsorption resin separation.

Lin Chen, Yunan Zhao, Zhong-li Wang, 2014, Chinese journal of natural medicines.

Preventive Action of Panax ginseng Roots in Hypercortisolism‐induced Impairment of Hippocampal Neurons in Male C57BL/6N Mice

Jianguo Dai, Lin Chen, Yunan Zhao, 2011, Phytotherapy research : PTR.

Hippocampal astrocyte atrophy in a mouse depression model induced by corticosterone is reversed by fluoxetine instead of benzodiazepine diazepam

Zixuan Lin, Feiyan Chen, Lin Chen, 2018, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Preventive effects of ginsenoside Rg1 on post-traumatic stress disorder (PTSD)-like behavior in male C57/B6 mice

Lin Chen, Yunan Zhao, Zhong-li Wang, 2015, Neuroscience Letters.

The Antidepressant Effects of Ginseng Total Saponins in Male C57BL/6 N Mice by Enhancing Hippocampal Inhibitory Phosphorylation of GSK‐3β

Jianguo Dai, Lin Chen, Yunan Zhao, 2014, Phytotherapy research : PTR.

Protein target identification of ginsenosides in skeletal muscle tissues: discovery of natural small-molecule activators of muscle-type creatine kinase

Zixuan Lin, Feiyan Chen, Jianguo Dai, 2019, Journal of ginseng research.

Preventive Effects of Ginseng Total Saponins on Chronic Corticosterone‐Induced Impairment in Astrocyte Structural Plasticity and Hippocampal Atrophy

Zixuan Lin, Lin Chen, Yunan Zhao, 2017, Phytotherapy research : PTR.

Ginseng Total Saponins Reverse Corticosterone-Induced Changes in Depression-Like Behavior and Hippocampal Plasticity-Related Proteins by Interfering with GSK-3β-CREB Signaling Pathway

Jianguo Dai, Lin Chen, Yunan Zhao, 2014, Evidence-based complementary and alternative medicine : eCAM.

Rabbit conjunctivae edema and release of NO, TNF-α, and IL-1β from macrophages induced by fractions and esculentosides isolated from Phytolacca americana

Hong-li Yu, Hao Wu, Kui-long Wang, 2016, Pharmaceutical biology.

Qualitative detection of ginsenosides in brain tissues after oral administration of high-purity ginseng total saponins by using polyclonal antibody against ginsenosides.

Lin Chen, Yunan Zhao, Ling Gu, 2018, Chinese journal of natural medicines.

Determination of total ginsenosides in ginseng extracts using charged aerosol detection with post-column compensation of the gradient.

Lin Chen, Yunan Zhao, Zhong-li Wang, 2014, Chinese journal of natural medicines.

Decreased Glycogen Content Might Contribute to Chronic Stress-Induced Atrophy of Hippocampal Astrocyte volume and Depression-like Behavior in Rats

Lin Chen, Yunan Zhao, Xin Wang, 2017, Scientific Reports.

Protective Effect of 20(S)-Protopanaxadiol on D-Gal-Induced Cognitively Impaired Mice Based on Its Target Protein Brain-type Creatine Kinase.

Feiyan Chen, Zhu Zhu, Lin Chen, 2023, Journal of agricultural and food chemistry.

Discovery and validation of PURA as a transcription target of 20(S)-protopanaxadiol: Implications for the treatment of cognitive dysfunction

Wenjing Zhang, Feiyan Chen, Zhu Zhu, 2023, Journal of Ginseng Research.

Target engagement of ginsenosides in mild cognitive impairment using mass spectrometry-based drug affinity responsive target stability

Ruimei Li, Feiyan Chen, Zhu Zhu, 2021, Journal of ginseng research.

20(S)-Protopanaxadiol Exerts Antidepressive Effects in Chronic Corticosterone-Induced Rodent Animal Models as an Activator of Brain-Type Creatine Kinase.

Feiyan Chen, Zhu Zhu, Lin Chen, 2024, Journal of agricultural and food chemistry.