B. Karlén

发表

Evidence for two catalytically different binding sites of liver microsomal cytochrome P-450: importance for species and sex differences in oxidation pattern of lidocaine.

H. Grasdalen, C. von Bahr, I. Hedlund, 2009, Acta pharmacologica et toxicologica.

EVIDENCE FOR BINDING OF LIDOCAINE TO TWO CATALYTICALLY DIFFERENT SITES OF LIVER MICROSOMAL CYTOCHROME P-450

C. Bahr, H. Grasdalen, I. Hedlund, 1977 .

Extraction and metabolism of lidocaine in rat liver.

C. von Bahr, I. Hedlund, B. Karlén, 2009, Acta pharmacologica et toxicologica.

Effect of physostigmine and atropine on acetylcholine turnover in mouse brain

B. Karlén, B. Holmstedt, G. Lundgren, 1979, Naunyn-Schmiedeberg's Archives of Pharmacology.

Metrifonate and tacrine: a comparative study on their effect on acetylcholine dynamics in mouse brain.

B. Karlén, M. Kimland, I. Nordgren, 1992, Pharmacology & toxicology.

Intoxications with anticholinesterases: effect of different combinations of antidotes on the dynamics of acetylcholine in mouse brain.

B. Karlén, M. Kimland, B. Holmstedt, 1992, Pharmacology & toxicology.

Effects of diazepam on blood choline and acetylcholine turnover in brain of mice.

G. Jacobsson, B. Karlén, G. Lundgren, 1987, Pharmacology & toxicology.

Acetylcholine Turnover in Mouse Brain: Influence of Cholinesterase Inhibitors

B. Karlén, B. Holmstedt, G. Lundgren, 1986 .

Distribution and elimination of the stereoisomers of soman and their effect on brain acetylcholine.

G. Puu, B. Karlén, B. Holmstedt, 1985, Fundamental and applied toxicology : official journal of the Society of Toxicology.

On the turnover of acetylcholine in mouse brain: influence of dose size of deuterium labelled choline given as precursor.

B. Karlén, B. Holmstedt, G. Lundgren, 1982, Biochemical pharmacology.

Effect of Atropine on Acetylcholine Metabolism in the Mouse Brain

T. Miyata, B. Karlén, B. Holmstedt, 1978 .

Effects of diazepam on muscarinic acetylcholine receptor binding in vivo and on oxotremorine-induced tremor and hypothermia in mice.

B. Karlén, G. Lundgren, I. Nordgren, 1987, Pharmacology & toxicology.

Abundance and Run Timing of Adult Salmon in the Tozitna River, Alaska, 2003

B. Karlén, Tim Sundlov, Carl Kretsinger, 2005 .

Acetylcholine and choline in mouse brain--influence of peripherally acting cholinergic drugs.

B. Karlén, B. Holmstedt, G. Lundgren, 1977, Biochemical pharmacology.

Stereoselectivity of muscarinic receptors in vivo and in vitro for oxotremorine analogues. N-[4-(tertiary amino)-2-butynyl]-5-methyl-2-pyrrolidones.

D. Jenden, R. Amstutz., M. Roch, 1985, Journal of medicinal chemistry.

The metabolism of tremorine. Identification of a new biologically active metabolite, N-(4-pyrrolidino-2-2-butynyl)-gamma-aminobutyric acid.

J. Vessman, F. Sjöqvist, B. Karlén, 1968, Biochemical pharmacology.

The influence of body temperature on the elimination of oxotremorine in the mouse.

F. Sjöqvist, B. Karlén, W. Hammer, 1968, Biochemical pharmacology.

Rate of metabolism of tremorine and oxotremorine in rats and mice.

A. Rane, F. Sjöqvist, B. Karlén, 1968, Life sciences.

N‐(Perhydroazepinoalkynyl)‐ and N‐(perhydroazocinoalkynyl) succinimides as oxotremorine antagonists

B. Karlén, S. Lindgren, B. Lindeke, 1970, The Journal of pharmacy and pharmacology.

Acetylene compounds of potential pharmacological value. XIV. N-(t-aminoalkynyl)-substituted succinimides and maleimides. A class of central anticholinergic agents.

D. Jenden, B. Karlén, S. Lindgren, 1970, Journal of medicinal chemistry.

Acetylene compounds of potential pharmacological value. 8. N-(4-dialkylamino-2-butynyl)-substituted cyclic imides.

D. Jenden, B. Karlén, R. Dahlbom, 1966, Journal of medicinal chemistry.

Synthesis and pharmacology of N-(4-diethylamino-2-butynyl)-succinimide (DKJ 21), a new central anticholinergic agent.

D. Jenden, B. Karlén, R. Dahlbom, 1966, Life sciences.

Synthesis and pharmacology of 1‐(2‐thioxopyrrolidino)‐4‐pyrrolidino‐2‐butyne, the thiolactam analogue of oxotremorine

D. Jenden, B. Karlén, R. Green, 1972, The Journal of pharmacy and pharmacology.

Metabolism of lidocaine in human liver in vitro.

H. Glaumann, J. Hermansson, C. von Bahr, 2009, Acta Pharmacologica et Toxicologica.

Pregnanolone emulsion A preliminary pharmacokinetic and pharmacodynamic study of a new intravenous anaesthetic agent

B. Karlén, S. Høgskilde, P. Carl, 1990, Anaesthesia.

Atropine in mouse brain and plasma quantified by mass fragmentography.

J. Edgar, J. Hermansson, B. Karlén, 2009, Acta pharmacologica et toxicologica.

Identification of Acetylcholine in Fresh Rat Brain by Combined Gas Chromatography–Mass Spectrometry

D. Jenden, R. Kitz, I. Hanin, 1968, Nature.

Assay of the major (4-hydroxylated) metabolites of diphenylhydantoin in human urine

A. Rane, M. Garle, B. Karlén, 1975, European Journal of Clinical Pharmacology.

Assay of the major (4-hydroxylated) metabolite of diphenylhydantoin in human urine by reversed-phase high-performane liquid chromatography.

J. Hermansson, B. Karlén, 1977, Journal of chromatography.

Pharmacokinetics of terodiline in human volunteers

U. Ulmsten, K. Andersson, S. Strömberg, 2004, European Journal of Clinical Pharmacology.

A method using L-hyoscyamine for the study of muscarinic acetylcholine receptor binding in vivo.

B. Karlén, G. Lundgren, L. Palmér, 1987, Pharmacology & toxicology.

Absorption of boron after mouthwash treatment with Bocosept

A. Rosén, B. Karlén, L. Edwall, 1979, European Journal of Clinical Pharmacology.

Content of active ingredients in medicinal products: an approach to rational specification limits

B. Karlén, G. Nilsson, Jonas Tornblom, 1986 .

Acetylene compounds of potential pharmacological value. 18. N-(t-aminoalkynyl)-substituted 2-pyrrolidones, a new series of potent oxotremorine antagonists.

U. Svensson, B. Karlén, S. Lindgren, 1973, Acta pharmaceutica Suecica.

Acetylene compounds of potential pharmacological value. XXVIII. Oxotremorine analogues substituted with a methyl group in the lactam ring.

B. Ringdahl, Z. Muhi-eldeen, B. Karlén, 1979, Acta pharmaceutica Suecica.

Drug-induced changes in brain levels of oxotremorine in mice.

F. Sjöqvist, B. Karlén, W. Hammer, 1968, Life sciences.