Wei Li

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Discovery of a novel mesothelin specific human antibody VH domain

D. Dimitrov, J. Mellors, R. Ishima, 2022 .

High Potency of a Bivalent Human VH Domain in SARS-CoV-2 Animal Models

S. Subramaniam, D. Dimitrov, R. Baric, 2020, Cell.

One-domain CD4 Fused to Human Anti-CD16 Antibody Domain Mediates Effective Killing of HIV-1-Infected Cells

D. Dimitrov, T. Ying, Liying Ma, 2017, Scientific Reports.

Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection

Lisa E. Gralinski, D. Dimitrov, R. Baric, 2020, Proceedings of the National Academy of Sciences.

Potent neutralization of SARS-CoV-2 by human antibody heavy-chain variable domains isolated from a large library with a new stable scaffold

D. Dimitrov, R. Baric, J. Mellors, 2020, mAbs.

Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody

D. Dimitrov, T. Zhou, Lingshu Wang, 2015, Nature Communications.

Cryo-EM Structure of the N501Y SARS-CoV-2 Spike Protein in Complex with a Potent Neutralizing Antibody

S. Subramaniam, D. Dimitrov, J. Demers, 2021, bioRxiv.

Half-life extension enhances drug efficacy in adeno-associated virus delivered gene therapy

D. Dimitrov, T. Ying, Yanling Wu, 2022, Engineering.

Potent and broad neutralization of SARS-CoV-2 variants of concern (VOCs) including omicron sub-lineages BA.1 and BA.2 by biparatopic human VH domains

Michele D. Sobolewski, M. H. Cheng, I. Bahar, 2022, iScience.

Enhanced elicitation of potent neutralizing antibodies by the SARS-CoV-2 spike receptor binding domain Fc fusion protein in mice

D. Dimitrov, J. Mellors, A. Drelich, 2020, Vaccine.

Human Antibody Domains and Fragments Targeting Neutrophil Elastase as Candidate Therapeutics for Cancer and Inflammation-Related Diseases

D. Dimitrov, J. Mellors, S. Shapiro, 2021, International journal of molecular sciences.

Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma

Christopher S. Hughes, P. Sorensen, D. Dimitrov, 2021, Cancer discovery.

Discovery of a novel human antibody VH domain with potent activity against mesothelin expressing cancer cells in both CAR T-cell and antibody drug conjugate formats

D. Dimitrov, J. Mellors, R. Ishima, 2022, bioRxiv.

Protocol for constructing large size human antibody heavy chain variable domain (VH) library and selection of SARS-CoV-2 neutralizing antibody domains

D. Dimitrov, Zehua Sun, Xianglei Liu, 2021, STAR Protocols.

Potent neutralization of SARS-CoV-2 in vitro and in an animal model by a human monoclonal antibody

Lisa E. Gralinski, D. Dimitrov, R. Baric, 2020, bioRxiv.

A defucosylated bispecific multivalent molecule exhibits broad HIV-1-neutralizing activity and enhanced antibody-dependent cellular cytotoxicity against reactivated HIV-1 latently infected cells

D. Dimitrov, K. Hong, Y. Shao, 2018, AIDS.

Potent neutralization of SARS-CoV-2 in vitro and in an animal model by a human monoclonal antibody.

Lisa E. Gralinski, D. Dimitrov, R. Baric, 2020, bioRxiv : the preprint server for biology.

Rapid selection of a human monoclonal antibody that potently neutralizes SARS-CoV-2 in two animal models

Lisa E. Gralinski, D. Dimitrov, R. Baric, 2020 .

RETRACTED ARTICLE: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs

Amber K Weiner, S. Stevanović, D. Dimitrov, 2021, Nature.

Differential killing of CD56-expressing cells by drug-conjugated human antibodies targeting membrane-distal and membrane-proximal non-overlapping epitopes

D. Dimitrov, J. Maris, Zhongyu Zhu, 2016, mAbs.

Human antibodies targeting ENPP1 as candidate therapeutics for cancers

D. Dimitrov, G. Morin, Xiaojie Chu, 2023, Frontiers in Immunology.

Identification of high-affinity anti-CD16A allotype-independent human antibody domains.

D. Dimitrov, Wei Li, Hongjia Yang, 2016, Experimental and molecular pathology.

Structural details of monoclonal antibody m971 recognition of the membrane-proximal domain of CD22

D. Dimitrov, J. Julien, Yang Feng, 2021, The Journal of biological chemistry.

Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding

S. Subramaniam, D. Dimitrov, J. Saville, 2021, bioRxiv.

Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants

S. Subramaniam, D. Dimitrov, J. Demers, 2022, Nature Communications.

Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants

S. Subramaniam, D. Dimitrov, J. Demers, 2021, Nature Communications.

Discovery and pre-clinical evaluation of antibodies to the NKG2A inhibitory receptor

D. Dimitrov, J. Mellors, J. Cyktor, 2022, bioRxiv.

FGFR4-Targeted Chimeric Antigen Receptors Combined with Anti-Myeloid Polypharmacy Effectively Treat Orthotopic Rhabdomyosarcoma

D. Dimitrov, R. Orentas, Rajesh Kumar, 2022, Molecular cancer therapeutics.

Construction of a Large Size Human Immunoglobulin Heavy Chain Variable (VH) Domain Library, Isolation and Characterization of Novel Human Antibody VH Domains Targeting PD-L1 and CD22

D. Dimitrov, J. Mellors, R. Orentas, 2022, Frontiers in Immunology.

Chimeric antigen receptor-T cells are effective against CEACAM5 expressing non-small cell lung cancer cells resistant to antibody-drug conjugates

D. Dimitrov, J. Mellors, D. Zhelev, 2023, Frontiers in Oncology.

One-domain CD4 Fused to Human Anti-CD16 Antibody Domain Mediates Effective Killing of HIV-1-Infected Cells

D. Dimitrov, T. Ying, Liying Ma, 2017, Scientific Reports.

Optimization of the C-terminus of an autonomous human IgG1 CH2 domain for stability and aggregation resistance.

D. Dimitrov, R. Gong, Fang Zeng, 2019, Molecular pharmaceutics.

Potent Neutralization of Omicron and other SARS-CoV-2 Variants of Concern by Biparatopic Human VH Domains

M. H. Cheng, S. Subramaniam, I. Bahar, 2022, bioRxiv.

SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization

S. Subramaniam, D. Dimitrov, J. Mellors, 2022, Nature Communications.

Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies

S. Subramaniam, D. Dimitrov, J. Demers, 2021, PLoS biology.

Human Antibody VH Domains Targeting GPNMB and VCAM-1 as Candidate Therapeutics for Cancers

D. Dimitrov, J. Mellors, I. Lyakhov, 2023, Molecular pharmaceutics.

Article type: Short communication Title: Neutralization of European, South African, and United States SARS-CoV-2 mutants by a human antibody and antibody domains Authors:

D. Dimitrov, J. Mellors, K. McCormick, 2021 .

Development of an efficient method for selection of stable cell pools for protein expression and surface display with Expi293F cells

D. Dimitrov, Zehua Sun, Chuan Chen, 2023, Cell biochemistry and function.

Rapid Elimination of Broadly Neutralizing Antibodies Correlates with Treatment Failure in the Acute Phase of Simian-Human Immunodeficiency Virus Infection

D. Dimitrov, P. Prabakaran, I. Sidorov, 2019, Journal of Virology.

Engineering a Novel Antibody-Peptide Bispecific Fusion Protein Against MERS-CoV

D. Dimitrov, T. Ying, F. Yu, 2019, Antibodies.

Human Domain Antibodies to Conserved Epitopes on HER2 Potently Inhibit Growth of HER2-Overexpressing Human Breast Cancer Cells In Vitro

D. Dimitrov, Wei-zao Chen, Yanping Wang, 2019, Antibodies.

Preclinical assessment of a novel human antibody VH domain targeting mesothelin as an antibody-drug conjugate

D. Dimitrov, R. Ishima, Xiaojie Chu, 2023, Molecular therapy oncolytics.

The reduced form of the antibody CH2 domain

D. Dimitrov, R. Ishima, Xianglei Liu, 2021, Protein science : a publication of the Protein Society.

Assessment of Novel Mesothelin-Specific Human Antibody Domain VH-Fc Fusion Proteins-Based PET Agents

R. Ishima, Xiaojie Chu, Abhinav Bhise, 2023, ACS omega.

Targeting of intracellular oncoproteins with peptide-centric CARs

J. Maris, N. Sgourakis, S. Tripathi, 2023, Nature.