D. Mannar

发表

High Potency of a Bivalent Human VH Domain in SARS-CoV-2 Animal Models

S. Subramaniam, D. Dimitrov, R. Baric, 2020, Cell.

Glycan reactive anti-HIV-1 antibodies bind the SARS-CoV-2 spike protein but do not block viral entry

S. Subramaniam, K. Leopold, D. Mannar, 2021, Scientific Reports.

Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation

S. Subramaniam, C. Arrowsmith, A. Hutchinson, 2022, Nature Chemical Biology.

Cryo-EM Structure of the N501Y SARS-CoV-2 Spike Protein in Complex with a Potent Neutralizing Antibody

S. Subramaniam, D. Dimitrov, J. Demers, 2021, bioRxiv.

Potent and broad neutralization of SARS-CoV-2 variants of concern (VOCs) including omicron sub-lineages BA.1 and BA.2 by biparatopic human VH domains

Michele D. Sobolewski, M. H. Cheng, I. Bahar, 2022, iScience.

Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation

S. Subramaniam, F. Bénard, C. Arrowsmith, 2022, Nature Chemical Biology.

Biochemical and Structural Characterization of Human Core Elongator and Its Subassemblies

U. Dalwadi, C. Yip, D. Mannar, 2022, ACS omega.

Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein

S. Subramaniam, J. Saville, A. Berezuk, 2023, Cell Reports.

SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein–ACE2 complex

S. Subramaniam, I. Sekirov, J. Saville, 2022, Science.

Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding

S. Subramaniam, D. Dimitrov, J. Saville, 2021, bioRxiv.

Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants

S. Subramaniam, D. Dimitrov, J. Demers, 2022, Nature Communications.

SARS-CoV-2 Omicron Variant: ACE2 Binding, Cryo-EM Structure of Spike Protein-ACE2 Complex and Antibody Evasion

S. Subramaniam, I. Sekirov, J. Saville, 2021, bioRxiv.

Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants

S. Subramaniam, D. Dimitrov, J. Demers, 2021, Nature Communications.

Potent Neutralization of Omicron and other SARS-CoV-2 Variants of Concern by Biparatopic Human VH Domains

M. H. Cheng, S. Subramaniam, I. Bahar, 2022, bioRxiv.

SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization

S. Subramaniam, D. Dimitrov, J. Mellors, 2022, Nature Communications.

Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies

S. Subramaniam, D. Dimitrov, J. Demers, 2021, PLoS biology.

SARS-CoV-2 variants Omicron BA.4/5 and XBB.1.5 significantly escape T cell recognition in solid organ transplant recipients vaccinated against the ancestral strain

Deepali Kumar, M. Levings, V. Ferreira, 2023, medRxiv.

Structure, activity and inhibition of human TMPRSS2, a protease implicated in SARS-CoV-2 activation

S. Subramaniam, F. Bénard, C. Arrowsmith, 2021, bioRxiv.

Cryo-EM structure of the SARS-CoV-2 Omicron spike protein

J. Saville, S. Subramaniam, A. Berezuk, 2021 .

AAA ATPase protein-protein interactions as therapeutic targets in cancer.

D. Mannar, Sriram Subramaniam, Sana Ahmed, 2023, Current opinion in cell biology.