Paolo Trifiró

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.

S. Minucci, C. Mercurio, L. Moretti, 2017, Journal of medicinal chemistry.

Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models.

S. Minucci, C. Mercurio, C. So, 2020, ACS medicinal chemistry letters.

Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A.

A. Mai, S. Minucci, M. Tortorici, 2014, European journal of medicinal chemistry.

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration.

S. Minucci, C. Mercurio, L. Moretti, 2017, Journal of medicinal chemistry.

Novel potent inhibitors of the histone demethylase KDM1A (LSD1), orally active in a murine promyelocitic leukemia model.

S. Minucci, C. Mercurio, M. Villa, 2017, Future medicinal chemistry.

Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent.

A. Mai, S. Minucci, C. Mercurio, 2016, Journal of medicinal chemistry.

Further insights into the SAR of α-substituted cyclopropylamine derivatives as inhibitors of histone demethylase KDM1A.

C. Mercurio, M. Villa, M. Varasi, 2015, European journal of medicinal chemistry.