Jianxia Guo

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Pharmacokinetics and tissue distribution of inositol hexaphosphate in C.B17 SCID mice bearing human breast cancer xenografts.

I. Vucenik, J. Eiseman, E. Joseph, 2011, Metabolism: clinical and experimental.

Visual P300 as a neurophysiological correlate of symptomatic improvement by a virtual reality-based computer AT system in patients with auditory verbal hallucinations: A Pilot study.

Wentao Zhao, Sha Liu, Yong Xu, 2022, Journal of psychiatric research.

In vitro cytotoxicity and in vivo efficacy, pharmacokinetics, and metabolism of pyrazole-based small molecule inhibitors of Mdm2/4–p53 interaction

A. Dömling, Yijun Huang, J. Beumer, 2015, Cancer Chemotherapy and Pharmacology.

Evaluation of the pharmacokinetic drug-drug interaction potential of iohexol, a renal filtration marker

E. Chu, S. Ivy, R. Venkataramanan, 2020, Cancer Chemotherapy and Pharmacology.

Exceptional activity of murine glutathione transferase A1‐1 against (7R,8S)‐dihydroxy‐(9S,10R)‐epoxy‐7,8,9,10‐tetrahydrobenzo[a]pyrene–induced DNA damage in stably transfected cells

Shivendra V. Singh, S. Pan, Jianxia Guo, 2003, Molecular carcinogenesis.

Differential expression of glutathione S-transferase isoenzymes in murine small intestine and colon.

Shivendra V. Singh, Jianxia Guo, J. Orchard, 2002, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Critical role of allyl groups and disulfide chain in induction of Pi class glutathione transferase in mouse tissues in vivo by diallyl disulfide, a naturally occurring chemopreventive agent in garlic.

S. Srivastava, Shivendra V. Singh, C. Bose, 2002, Carcinogenesis.

Combination Therapy with Disulfiram, Copper, and Doxorubicin for Osteosarcoma: In Vitro Support for a Novel Drug Repurposing Strategy

R. Watters, K. Weiss, J. Beumer, 2019, Sarcoma.

Blocking the ZZ Domain of Sequestosome1/p62 Suppresses Myeloma Growth and Osteoclast Formation In Vitro and Induces Dramatic Bone Formation in Myeloma-Bearing Bones In Vivo

Wei Zhao, X. Xie, K. Mohammad, 2015, Leukemia.

Pharmacology and antitumor activity of a quinolinedione Cdc25 phosphatase inhibitor DA3003-1 (NSC 663284).

P. Wipf, J. Lazo, M. Egorin, 2007, Anticancer research.

Improved chemosensitivity following mucolytic therapy in patient-derived models of mucinous appendix cancer.

L. Foley, T. Hitchens, L. Rigatti, 2020, Translational research : the journal of laboratory and clinical medicine.

Liquid chromatography-tandem mass spectrometric assay for the quantitation of the novel radiation protective agent and radiation mitigator JP4-039 in murine plasma.

P. Wipf, J. Greenberger, J. Beumer, 2018, Journal of pharmaceutical and biomedical analysis.

In vitro cytotoxicity, pharmacokinetics, tissue distribution, and metabolism of small-molecule protein kinase D inhibitors, kb-NB142-70 and kb-NB165-09, in mice bearing human cancer xenografts

P. Wipf, M. Egorin, J. Beumer, 2013, Cancer Chemotherapy and Pharmacology.

Dose-dependent bioavailability, absorption-rate limited elimination, and tissue distribution of the ATR inhibitor BAY-1895344 (elimusertib) in mice

C. Bakkenist, B. Kiesel, J. Beumer, 2022, Cancer Chemotherapy and Pharmacology.

Quantitation of iohexol, a glomerular filtration marker, in human plasma by LC-MS/MS.

E. Chu, S. Ivy, B. Kiesel, 2020, Journal of pharmaceutical and biomedical analysis.

Secondary Cytoreduction and Carboplatin Hyperthermic Intraperitoneal Chemotherapy for Platinum-Sensitive Recurrent Ovarian Cancer: An MSK Team Ovary Phase II Study

D. Chi, A. Iasonos, C. Aghajanian, 2021, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Evaluation of Silicon Phthalocyanine 4 Photodynamic Therapy Against Human Cervical Cancer Cells In Vitro and in Mice.

P. Basse, J. Eiseman, J. Comerci, 2016, Advances in biological chemistry.

Metallothionein protects against doxorubicin-induced cardiomyopathy through inhibition of superoxide generation and related nitrosative impairment.

S. Peng, Jiabin Guo, Yan-sheng Dong, 2007, Toxicology letters.

Phase I and Pharmacodynamic Study of 17-(Allylamino)-17-Demethoxygeldanamycin in Adult Patients with Refractory Advanced Cancers

S. Ramalingam, E. Zuhowski, M. Egorin, 2007, Clinical Cancer Research.

Evaluation of Plasma Insulin-like Growth Factor Binding Protein 2 and Her-2 Extracellular Domain as Biomarkers for 17-Allylamino-17-Demethoxygeldanamycin Treatment of Adult Patients with Advanced Solid Tumors

H. Scher, D. Solit, E. Zuhowski, 2007, Clinical Cancer Research.

Murine toxicology and pharmacokinetics of lead next generation galeterone analog, VNPP433-3β

P. Purushottamachar, V. Njar, J. Beumer, 2023, Steroids.

In Vitro Cytotoxicity and In Vivo Efficacy, Pharmacokinetics, and Metabolism of 10074-G5, a Novel Small-Molecule Inhibitor of c-Myc/Max Dimerization

E. Prochownik, J. Lazo, M. Egorin, 2010, Journal of Pharmacology and Experimental Therapeutics.

Dose-Dependent Bioavailability and Tissue Distribution of the ATR Inhibitor AZD6738 (ceralasertib) in Mice

C. Bakkenist, R. Venkataramanan, B. Kiesel, 2022, Cancer Chemotherapy and Pharmacology.

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E. Prochownik, M. Egorin, J. Beumer, 2010 .

Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc–Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice

E. Prochownik, J. Lazo, M. Egorin, 2009, Cancer Chemotherapy and Pharmacology.

Toxicity, pharmacokinetics and metabolism of a novel inhibitor of IL-6-induced STAT3 activation

J. Grandis, D. Huryn, P. Johnston, 2016, Cancer Chemotherapy and Pharmacology.

Cloning and expression of a novel Mu class murine glutathione transferase isoenzyme.

Shivendra V. Singh, P. Zimniak, Jianxia Guo, 2002, The Biochemical journal.

Evaluation of plasma insulin-like growth factor binding protein 2 (IGFBP-2) as a biomarker for 17-allylamino-17-demethoxygeldanamycin (17-AAG) treatment of adult patients (pts) with advanced solid tumors

H. Scher, D. Solit, E. Zuhowski, 2005 .

ALDH1A1 Gene Expression and Cellular Copper Levels between Low and Highly Metastatic Osteosarcoma Provide a Case for Novel Repurposing with Disulfiram and Copper

G. Intini, C. Anderson, R. Watters, 2022, Sarcoma.

In vitro evaluation of the metabolic enzymes and drug interaction potential of triapine

E. Chu, R. Venkataramanan, B. Kiesel, 2020, Cancer Chemotherapy and Pharmacology.

LC–MS/MS assay for the quantitation of the ribonucleotide reductase inhibitor triapine in human plasma

E. Chu, B. Kiesel, J. Beumer, 2017, Journal of pharmaceutical and biomedical analysis.

Modular Smart Molecules for PSMA-Targeted Chemotherapy.

C. Anderson, J. Beumer, C. Berkman, 2022, Molecular cancer therapeutics.

Mass Balance Study of the Engineered Cationic Antimicrobial Peptide, WLBU2, Following a Single Intravenous Dose of 14C-WLBU2 in Mice.

R. Montelaro, B. Deslouches, J. Eiseman, 2020, Current clinical pharmacology.

The Relationship of Phthalocyanine 4 (Pc 4) Concentrations Measured Noninvasively to Outcome of Pc 4 Photodynamic Therapy in Mice

J. Eiseman, Jianxia Guo, Lihua Bai, 2009, Photochemistry and photobiology.

Crystal structure of human glutathione S-transferase A3-3 and mechanistic implications for its high steroid isomerase activity.

Shivendra V. Singh, P. Zimniak, S. Pan, 2004, Biochemistry.

Noninvasive and nondestructive optical spectroscopic measurement of motexafin gadolinium in mouse tissues: comparison to high-performance liquid chromatography.

R. Parker, S. Kanick, J. Eiseman, 2007, Journal of photochemistry and photobiology. B, Biology.

Noninvasive assessment of tissue distribution and tumor pharmacokinetics of Pc 181, a silicon phthalocyanine analogue, in mice

Lihua Bai, Jianxia Guo, Dana M. Clausen, 2010, BiOS.

Non-linear IV pharmacokinetics of the ATR inhibitor berzosertib (M6620) in mice.

C. Bakkenist, D. D’Argenio, R. Parise, 2024, Cancer chemotherapy and pharmacology.