C. Celeghini

发表

The induction of megakaryocyte differentiation is accompanied by selective Ser133 phosphorylation of the transcription factor CREB in both HEL cell line and primary CD34+ cells.

P. Secchiero, M. Vitale, S. Capitani, 1998, Blood.

Potential pathogenetic implications of cyclooxygenase-2 overexpression in B chronic lymphoid leukemia cells.

Stefano A Pileri, Claudio Agostinelli, S. Pileri, 2005, American Journal of Pathology.

Activation of the nitric oxide synthase pathway represents a key component of tumor necrosis factor-related apoptosis-inducing ligand-mediated cytotoxicity on hematologic malignancies.

P. Secchiero, A. Gonelli, S. Capitani, 2001, Blood.

Modulation of the expression and activity of cyclooxygenases in normal and accelerated erythropoiesis.

C. Patrono, E. Barbarotto, N. Maggiano, 2004, Experimental hematology.

Tat‐expressing Jurkat cells show an increased resistance to different apoptotic stimuli, including acute human immunodeficiency virus‐type 1 (HIV ‐1) infection

S. Capitani, G. Zauli, A. Caputo, 1995, British journal of haematology.

P. Secchiero, G. Zauli, E. Rimondi, 2004, Blood.

An increased osteoprotegerin serum release characterizes the early onset of diabetes mellitus and may contribute to endothelial cell dysfunction.

P. Secchiero, F. Corallini, S. Capitani, 2006, The American journal of pathology.

Dexamethasone counteracts the anti‐osteoclastic, but not the anti‐leukemic, activity of TNF‐related apoptosis inducing ligand (TRAIL)

P. Secchiero, G. Zauli, D. Milani, 2010, Journal of cellular physiology.

Treatment With Recombinant Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Alleviates the Severity of Streptozotocin-Induced Diabetes

P. Secchiero, G. Zauli, B. Fabris, 2010, Diabetes.

TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress

C. Cervellati, P. Secchiero, G. Zauli, 2018, Mediators of inflammation.

Association of Serum Tumor Necrosis Factor-Related Apoptosis Inducing Ligand with Body Fat Distribution as Assessed by Dual X-Rays Absorptiometry

C. Cervellati, P. Secchiero, G. Zauli, 2014, Mediators of inflammation.

Release of a specific set of proinflammatory adipokines by differentiating 3T3-L1 cells.

P. Secchiero, G. Zauli, I. Volpi, 2013, Nutrition.

Trail down‐regulates the release of osteoprotegerin (OPG) by primary stromal cells

P. Secchiero, F. Corallini, A. Gonelli, 2011, Journal of cellular physiology.

Repositioning of Tak-475 In Mevalonate Kinase Disease: Translating Theory Into Practice.

C. Loganes, A. Marcuzzi, C. Celeghini, 2018, Current medicinal chemistry.

Upregulation of SOCS-1 by Nutlin-3 in acute myeloid leukemia cells but not in primary normal cells

P. Secchiero, A. Gonelli, D. Milani, 2014, Clinics.

Thrombopoietin Enhances the αIIbβ3-Dependent Adhesion of Megakaryocytic Cells to Fibrinogen or Fibronectin Through PI 3 Kinase

M. Vitale, S. Capitani, G. Zauli, 1997 .

Thrombopoietin enhances the alpha IIb beta 3-dependent adhesion of megakaryocytic cells to fibrinogen or fibronectin through PI 3 kinase.

M. Vitale, S. Capitani, G. Zauli, 1997, Blood.

Association of PI 3-K with tyrosine phosphorylated Vav is essential for its activity in neutrophil-like maturation of myeloid cells.

S. Capitani, C. Carini, M. Marchisio, 2004, Cellular signalling.

The engagement of CD4 surface antigen in the HEL haemopoietic cell line up‐regulates the transforming growth factor‐β1 (TGF‐β1) promoter activity

P. Secchiero, S. Capitani, G. Zauli, 1997, British journal of haematology.

PI3K isoform inhibition associated with anti Bcr-Abl drugs shows in vitro increased anti-leukemic activity in Philadelphia chromosome-positive B-acute lymphoblastic leukemia cell lines

J. McCubrey, P. Ulivi, A. Martelli, 2017, Oncotarget.

In Vitro Senescence and Apoptotic Cell Death of Human Megakaryocytes

M. Vitale, S. Capitani, G. Zauli, 1997 .

Perifosine selectively induces cell cycle block and modulates retinoblastoma and E2F1 protein levels in p53 mutated leukemic cell lines

G. Zauli, V. Gattei, E. Rimondi, 2011, Investigational New Drugs.

Osteoprotegerin increases leukocyte adhesion to endothelial cells both in vitro and in vivo.

P. Secchiero, F. Corallini, G. Zauli, 2007, Blood.

in vitro and in vivo Osteoprotegerin increases leukocyte adhesion to endothelial cells both

P. Secchiero, F. Corallini, G. Zauli, 2013 .

differentiation induced by RANKL+M-CSF TNF-related apoptosis inducing ligand (TRAIL) blocks osteoclastic

G. Zauli, E. Rimondi, V. Nicolin, 2013 .

Effect of recombinant TRAIL in a murine co-culture system of osteoclastogenesis.

V. Nicolin, P. Narducci, C. Celeghini, 2009, European journal of histochemistry : EJH.

Complement component C1q as potential diagnostic but not predictive marker of preeclampsia

I. Sargent, T. Stampalija, F. Tedesco, 2016, American journal of reproductive immunology.

Morphological features of apoptosis in hematopoietic cells belonging to the T-lymphoid and myeloid lineages.

P. Secchiero, G. Zauli, A. Grilli, 2000, Cellular and molecular biology.

Geranylgeraniol and Neurological Impairment: Involvement of Apoptosis and Mitochondrial Morphology

L. Monasta, E. Piscianz, G. Baj, 2016, International journal of molecular sciences.

Selective modulation of specific protein kinase C (PKC) isoforms in primary human megakaryocytic vs. erythroid cells

M. Vitale, S. Capitani, G. Zauli, 1999, The Anatomical record.

Fine tuning of protein kinase C (PKC) isoforms in cancer: shortening the distance from the laboratory to the bedside.

G. Zauli, M. Vaccarezza, E. Rimondi, 2011, Mini reviews in medicinal chemistry.

Anti-leukemic activity of Dasatinib in both p53wild-type and p53mutated B malignant cells

P. Secchiero, F. Corallini, S. Capitani, 2012, Investigational New Drugs.

Erythropoietin (EPO)-induced erythroid differentiation of K562 cells is accompanied by the nuclear translocation of phosphatidylinositol 3-kinase and intranuclear generation of phosphatidylinositol (3,4,5) trisphosphate

G. Baldini, A. Martelli, S. Capitani, 2002 .

Extracellular Tat activates c‐fos promoter in low serum‐starved CD4+ T cells

G. Zauli, M. Re, D. Gibellini, 2001, British journal of haematology.

Potential role of circulating microRNAs as early markers of preeclampsia.

L. Monasta, G. Feriotto, S. Bilel, 2014, Taiwanese journal of obstetrics & gynecology.

Overcoming of Microenvironment Protection on Primary Chronic Lymphocytic Leukemia Cells after Treatment with BTK and MDM2 Pharmacological Inhibitors

P. Secchiero, G. Zauli, D. Milani, 2021, Current oncology.

Impaired survival of bone marrow GPIIb/IIIa+ megakaryocytic cells as an additional pathogenetic mechanism of HIV‐1‐related thrombocytopenia

S. Capitani, G. Zauli, N. Vianelli, 1996, British journal of haematology.

Ibrutinib synergizes with MDM-2 inhibitors in promoting cytotoxicity in B chronic lymphocytic leukemia

A. Cuneo, P. Secchiero, G. Zauli, 2016, Oncotarget.

Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3

A. Cuneo, P. Secchiero, G. Zauli, 2014, Oncotarget.

Perifosine plus nutlin‐3 combination shows a synergistic anti‐leukaemic activity

P. Secchiero, G. Zauli, R. Voltan, 2010, British journal of haematology.

Insulin down‐regulates TRAIL expression in vascular smooth muscle cells both in vivo and in vitro

F. Corallini, G. Zauli, M. Vaccarezza, 2007, Journal of cellular physiology.

Neuronal Dysfunction Associated with Cholesterol Deregulation

L. Monasta, A. Tommasini, E. Piscianz, 2018, International journal of molecular sciences.

Pleiotropic effects of immobilized versus soluble recombinant HIV-1 Tat protein on CD3-mediated activation, induction of apoptosis, and HIV-1 long terminal repeat transactivation in purified CD4+ T lymphocytes.

S. Capitani, G. Zauli, D. Gibellini, 1996, Journal of immunology.

The potential role of Nutlins in the treatment of B‐chronic lymphocytic leukemia (B‐CLL)

F. Corallini, C. Celeghini, 2008, Journal of leukocyte biology.

Human herpesvirus 7 induces the functional up-regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) coupled to TRAIL-R1 down-modulation in CD4(+) T cells.

P. Secchiero, A. Gonelli, M. Vitale, 2001, Blood.

Differential effects of stromal derived factor‐1α (SDF‐1α) on early and late stages of human megakaryocytic development

P. Secchiero, G. Zauli, R. Rana, 2000 .

Purinergic Signaling in Controlling Macrophage and T Cell Functions During Atherosclerosis Development

D. Ferrari, A. la Sala, D. Milani, 2021, Frontiers in Immunology.

Total extract of Beta vulgaris var. cicla seeds versus its purified phenolic components: antioxidant activities and antiproliferative effects against colon cancer cells.

D. Angelino, Manuela Blasa, L. Gennari, 2011, Phytochemical analysis : PCA.

Mitochondria-Targeted Antioxidants, an Innovative Class of Antioxidant Compounds for Neurodegenerative Diseases: Perspectives and Limitations

A. Gonelli, E. Rimondi, A. Marcuzzi, 2023, International journal of molecular sciences.

Activation of PKC-ε counteracts maturation and apoptosis of HL-60 myeloid leukemic cells in response to TNF family members

A. Gonelli, D. Milani, E. Rimondi, 2009, European journal of histochemistry : EJH.

An update on the xenograft and mouse models suitable for investigating new therapeutic compounds for the treatment of B-cell malignancies.

C. Tripodo, Francesco Saverio Tedesco, S. Zorzet, 2008, Current pharmaceutical design.

NF-κB pathways in hematological malignancies

L. Monasta, G. Zauli, C. Gasparini, 2014, Cellular and Molecular Life Sciences.

The sorafenib plus nutlin-3 combination promotes synergistic cytotoxicity in acute myeloid leukemic cells irrespectively of FLT3 and p53 status

F. Lanza, P. Secchiero, G. Zauli, 2012, Haematologica.

MCL1 down‐regulation plays a critical role in mediating the higher anti‐leukaemic activity of the multi‐kinase inhibitor Sorafenib with respect to Dasatinib

P. Secchiero, G. Zauli, R. Voltan, 2012, British journal of haematology.

TRAIL, OPG, and TWEAK in kidney disease: biomarkers or therapeutic targets?

C. Cervellati, P. Secchiero, G. Zauli, 2019, Clinical science.

P. Perri, P. Secchiero, A. Gonelli, 2015, BioMed research international.

HIV-1 Tat protects CD4+ Jurkat T lymphoblastoid cells from apoptosis mediated by TNF-related apoptosis-inducing ligand.

G. Zauli, A. Cappellini, M. Re, 2001, Cellular immunology.

Aberrant expression of TRAIL in B chronic lymphocytic leukemia (B‐CLL) cells

R. Fanin, E. Barbarotto, P. Secchiero, 2005, Journal of cellular physiology.

Pre‐eclampsia affects procalcitonin production in placental tissue

G. Ricci, I. Sargent, P. Zacchi, 2018, American journal of reproductive immunology.

Human Full-Length Osteoprotegerin Induces the Proliferation of Rodent Vascular Smooth Muscle Cells both in vitro and in vivo

F. Corallini, B. Fabris, R. Candido, 2009, Journal of Vascular Research.

P. Perri, P. Secchiero, A. Gonelli, 2015, BioMed research international.

Recent advances in the therapeutic perspectives of Nutlin-3.

P. Secchiero, G. Zauli, Paola Secchiero, 2011, Current pharmaceutical design.

Tumour necrosis factor‐related apoptosis‐inducing ligand sequentially activates pro‐survival and pro‐apoptotic pathways in SK‐N‐MC neuronal cells

P. Secchiero, S. Capitani, G. Zauli, 2003, Journal of neurochemistry.

Tumor necrosis factor-related apoptosis-inducing ligand induces monocytic maturation of leukemic and normal myeloid precursors through a caspase-dependent pathway.

P. Secchiero, A. Gonelli, G. Zauli, 2002, Blood.

Differential effects of stromal derived factor-1 alpha (SDF-1 alpha) on early and late stages of human megakaryocytic development.

P. Secchiero, G. Zauli, R. Rana, 2000, The Anatomical record.

A. Gonelli, G. Zauli, D. Milani, 2002 .

Design, Synthesis, and Biological Characterization of Novel Mitochondria Targeted Dichloroacetate-Loaded Compounds with Antileukemic Activity.

P. Secchiero, G. Zauli, S. Salvadori, 2016, Journal of medicinal chemistry.

Differential effects of chemotherapeutic drugs versus the MDM‐2 antagonist nutlin‐3 on cell cycle progression and induction of apoptosis in SKW6.4 lymphoblastoid B‐cells

E. Barbarotto, F. Corallini, M. Vaccarezza, 2008, Journal of cellular biochemistry.

NF-κB pathways in hematological malignancies

L. Monasta, G. Zauli, C. Gasparini, 2014, Cellular and Molecular Life Sciences.

In vitro senescence and apoptotic cell death of human megakaryocytes.

M. Vitale, S. Capitani, G. Zauli, 1997, Blood.

The expression levels of the pro-apoptotic XAF-1 gene modulate the cytotoxic response to Nutlin-3 in B chronic lymphocytic leukemia

P. Secchiero, G. Zauli, V. Gattei, 2010, Leukemia.

Functional expression of TRAIL and TRAIL‐R2 during human megakaryocytic development

P. Secchiero, G. Zauli, L. Guidotti, 2005, Journal of cellular physiology.

MitoQ Is Able to Modulate Apoptosis and Inflammation

E. Piscianz, E. Rimondi, E. Melloni, 2021, International journal of molecular sciences.

Soluble TRAIL is present at high concentrations in seminal plasma and promotes spermatozoa survival.

M. Martinelli, Stefania Luppi, G. Ricci, 2014, Reproduction.

Hydrogen sulfide down-regulates the expression and release of osteoprotegerin (OPG) by vascular endothelial cells

P. Secchiero, A. Gonelli, G. Zauli, 2012, Investigational new drugs.

PMA‐induced megakaryocytic differentiation of HEL cells is accompanied by striking modifications of protein kinase C catalytic activity and isoform composition at the nuclear level

S. Capitani, G. Zauli, P. Borgatti, 1996, British journal of haematology.

All-trans retinoic acid potentiates megakaryocyte colony formation: in vitro and in vivo effects after administration to acute promyelocytic leukemia patients.

G. Zauli, E. Ottaviani, S. Tura, 1994, Leukemia.

Retinal Alterations Predict Early Prodromal Signs of Neurodegenerative Disease

A. Gonelli, F. Casciano, C. Celeghini, 2024, International journal of molecular sciences.

Hiv-1 tat protein suppresses the nerve growth-factor (ngf)-mediated differentiation of PC12 rat pheochromocytoma cell-line.

S. Capitani, G. Zauli, M. Marchisio, 1994, Oncology reports.