C. Binda

发表

Diphenylene iodonium is a non-covalent MAO inhibitor: a biochemical and structural analysis.

A. Mai, A. Mattevi, J. Reis, 2020, ChemMedChem.

L. Chiarelli, A. Mattevi, M. Pasca, 2015 .

Functional role of the "aromatic cage" in human monoamine oxidase B: structures and catalytic properties of Tyr435 mutant proteins.

A. Mattevi, D. Edmondson, C. Binda, 2006, Biochemistry.

Structural insights into the mechanism of amine oxidation by monoamine oxidases A and B.

A. Mattevi, D. Edmondson, C. Binda, 2007, Archives of biochemistry and biophysics.

Structure and mechanism of monoamine oxidase.

A. Mattevi, D. Edmondson, F. Hubálek, 2004 .

Interactions of monoamine oxidases with the antiepileptic drug zonisamide: specificity of inhibition and structure of the human monoamine oxidase B complex.

A. Mattevi, D. Edmondson, C. Binda, 2011, Journal of medicinal chemistry.

The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis

L. Chiarelli, G. Manina, A. Mattevi, 2013, Applied Microbiology and Biotechnology.

Toxicity and risks from drug-to-drug interactions of new antivirals for chronic hepatitis C.

M. Garcovich, A. Tortora, B. Annicchiarico, 2017, European review for medical and pharmacological sciences.

Rational Redesign of Monoamine Oxidase A into a Dehydrogenase to Probe ROS in Cardiac Aging

A. Mattevi, J. Mialet-Perez, A. Parini, 2020, ACS chemical biology.

Tight-Binding Inhibition of Human Monoamine Oxidase B by Chromone Analogs: A Kinetic, Crystallographic, and Biological Analysis.

E. Uriarte, J. Mialet-Perez, A. Parini, 2018, Journal of medicinal chemistry.

Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments

G. Keserű, B. Vértessy, A. Perczel, 2020, ChemBioChem.

Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors.

D. Edmondson, Raed Shalaby, C. Binda, 2016, European journal of medicinal chemistry.

The structure of monoamine oxidases: past, present, and future

F. Magnani, L. G. Iacovino, C. Binda, 2018, Journal of Neural Transmission.

Monoamine oxidase‐A is a novel driver of stress‐induced premature senescence through inhibition of parkin‐mediated mitophagy

F. Lezoualc’h, J. Mialet-Perez, A. Parini, 2018, Aging cell.

Structural properties of human monoamine oxidases A and B.

A. Mattevi, D. Edmondson, C. Binda, 2011, International review of neurobiology.

Kinetic Resolution of sec-Thiols by Enantioselective Oxidation with Rationally Engineered 5-(Hydroxymethyl)furfural Oxidase.

M. Fraaije, A. Mattevi, K. Faber, 2018, Angewandte Chemie.

Monoamine Oxidases, Oxidative Stress, and Altered Mitochondrial Dynamics in Cardiac Ageing

A. Mattevi, J. Mialet-Perez, A. Parini, 2017, Oxidative medicine and cellular longevity.

Monoamine Oxidase Inhibitors Prevent Glucose-Dependent Energy Production, Proliferation and Migration of Bladder Carcinoma Cells

J. Mialet-Perez, A. Parini, B. Couderc, 2022, International journal of molecular sciences.

Supplementary Materials for Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis

R. Read, S. Cole, A. Lucarelli, 2012 .

Kinetic and structural analysis of the irreversible inhibition of human monoamine oxidases by ASS234, a multi-target compound designed for use in Alzheimer's disease.

A. Mattevi, R. Ramsay, G. Esteban, 2014, Biochimica et biophysica acta.

Crystallization and preliminary X-ray analysis of polyamine oxidase from Zea mays L.

P. Ascenzi, A. Mattevi, R. Angelini, 1998, Acta crystallographica. Section D, Biological crystallography.

Microsoft Word-NbtG Paperrevised 2.docx

Julia S. Martin del Campo, P. Sobrado, A. Mattevi, 2015 .

Tranylcypromine‐Based LSD1 Inhibitors: Structure‐Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation

A. Mai, S. Minucci, C. Mercurio, 2020, ChemMedChem.

Monoamine Oxidase Inhibitors: Diverse and Surprising Chemistry with Expanding Pharmacological Potential

A. Mattevi, D. Edmondson, C. Binda, 2013 .

Inhibition of Pig Liver and Zea mays L. Polyamine Oxidase: A Comparative Study

M. Botta, P. Ascenzi, R. Angelini, 2001, Journal of enzyme inhibition.

The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis

L. Chiarelli, G. Manina, A. Mattevi, 2013, Applied Microbiology and Biotechnology.

The FAD binding sites of human monoamine oxidases A and B.

A. Mattevi, D. Edmondson, C. Binda, 2004, Neurotoxicology.

Crystal structures of monoamine oxidase B in complex with four inhibitors of the N-propargylaminoindan class.

Andrea Mattevi, A. Mattevi, D. Edmondson, 2004, Journal of medicinal chemistry.

Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs.

Angelo Carotti, Leonardo Pisani, Andrea Mattevi, 2007, Journal of medicinal chemistry.

Assessment of tractable cysteines by covalent fragments screening.

S. Grdadolnik, G. Keserű, B. Vértessy, 2020, Chembiochem : a European journal of chemical biology.

New insights into the structures and functions of human monoamine oxidases A and B

A. Mattevi, D. Edmondson, C. Binda, 2007, Journal of Neural Transmission.

Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B.

Andrea Mattevi, A. Lustig, L. De Colibus, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Binding of rasagiline-related inhibitors to human monoamine oxidases: a kinetic and crystallographic analysis.

Andrea Mattevi, A. Mattevi, D. Edmondson, 2005, Journal of medicinal chemistry.

Structure-Function Relationships in Flavoenzyme-dependent Amine Oxidations

A. Mattevi, D. Edmondson, C. Binda, 2002, The Journal of Biological Chemistry.

A 30 Å long U-shaped catalytic tunnel in the crystal structure of polyamine oxidase

Paolo Ascenzi, Alessandro Coda, Andrea Mattevi, 1999 .

Crystal structure of human monoamine oxidase B, a drug target enzyme monotopically inserted into the mitochondrial outer membrane

A. Mattevi, D. Edmondson, F. Hubálek, 2004, FEBS letters.

8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases

J. Kos, M. Denic, J. Marco-Contelles, 2023, Acta pharmaceutica Sinica. B.

Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures

F. Ekström, M. Catto, L. Pisani, 2022, ACS medicinal chemistry letters.

Structure and mechanism of monoamine oxidase.

A. Mattevi, D. Edmondson, D E Edmondson, 2004, Current medicinal chemistry.

Discovery and characterization of an F420-dependent glucose-6-phosphate dehydrogenase (Rh-FGD1) from Rhodococcus jostii RHA1

M. Fraaije, A. Mattevi, G. Trinco, 2016, Applied Microbiology and Biotechnology.

Discovery and characterization of an F 420-dependent glucose-6-phosphate dehydrogenase ( Rh-FGD 1 ) from Rhodococcus jostii RHA 1

M. Fraaije, A. Mattevi, G. Trinco, 2016 .

Discovery and characterization of an F 420-dependent glucose-6-phosphate dehydrogenase ( Rh-FGD 1 ) from Rhodococcus jostii

M. Fraaije, A. Mattevi, G. Trinco, 2016 .

Isolation and characterization of a thermostable F420:NADPH oxidoreductase from Thermobifida fusca

M. Fraaije, A. Mattevi, H. Kumar, 2017, The Journal of Biological Chemistry.

The ‘gating’ residues Ile199 and Tyr326 in human monoamine oxidase B function in substrate and inhibitor recognition

A. Mattevi, D. Edmondson, C. Binda, 2011, The FEBS journal.

Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures

Andrea Mattevi, A. Mattevi, D. Edmondson, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Biocatalytic Characterization of Human FMO5: Unearthing Baeyer-Villiger Reactions in Humans.

A. Mattevi, M. Geier, M. Hall, 2016, ACS chemical biology.

Molecular and mechanistic properties of the membrane-bound mitochondrial monoamine oxidases.

A. Mattevi, D. Edmondson, A. Upadhyay, 2009, Biochemistry.

Allosteric transitions of rabbit skeletal muscle lactate dehydrogenase induced by pH-dependent dissociation of the tetrameric enzyme.

A. Hochkoeppler, F. Dal Piaz, M. Brigotti, 2022, Biochimie.

Demonstration of Isoleucine 199 as a Structural Determinant for the Selective Inhibition of Human Monoamine Oxidase B by Specific Reversible Inhibitors*

A. Mattevi, D. Edmondson, A. Khalil, 2005, Journal of Biological Chemistry.

Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2.

A. Mai, S. Minucci, F. Forneris, 2010, Journal of the American Chemical Society.

Alternative Splicing of the Histone Demethylase LSD1/KDM1 Contributes to the Modulation of Neurite Morphogenesis in the Mammalian Nervous System

F. Forneris, A. Mattevi, C. Verpelli, 2010, The Journal of Neuroscience.

New roles of flavoproteins in molecular cell biology: Histone demethylase LSD1 and chromatin

F. Forneris, A. Mattevi, E. Battaglioli, 2009, The FEBS journal.

A Novel Mammalian Flavin-dependent Histone Demethylase*

F. Forneris, A. Mattevi, A. Profumo, 2009, The Journal of Biological Chemistry.

LSD1: oxidative chemistry for multifaceted functions in chromatin regulation.

F. Forneris, A. Mattevi, E. Battaglioli, 2008, Trends in biochemical sciences.

Structural Basis of LSD1-CoREST Selectivity in Histone H3 Recognition*

F. Forneris, A. Mattevi, A. Adamo, 2007, Journal of Biological Chemistry.

Human Histone Demethylase LSD1 Reads the Histone Code*

F. Forneris, A. Mattevi, M. Vanoni, 2005, Journal of Biological Chemistry.

A 30-angstrom-long U-shaped catalytic tunnel in the crystal structure of polyamine oxidase.

P. Ascenzi, A. Mattevi, R. Angelini, 1999, Structure.

A Highly Specific Mechanism of Histone H3-K4 Recognition by Histone Demethylase LSD1*

F. Forneris, M. Fraaije, A. Mattevi, 2006, Journal of Biological Chemistry.

8 Demethylation pathways for histone methyllysine residues.

F. Forneris, A. Mattevi, M. Vanoni, 2006, The Enzymes.

Histone demethylation catalysed by LSD1 is a flavin‐dependent oxidative process

F. Forneris, A. Mattevi, M. Vanoni, 2005, FEBS letters.

Structural and mechanistic studies of arylalkylhydrazine inhibition of human monoamine oxidases A and B.

A. Mattevi, D. Edmondson, F. Hubálek, 2008, Biochemistry.

Molecular mimicry and ligand recognition in binding and catalysis by the histone demethylase LSD1-CoREST complex.

J. Mccammon, R. Baron, M. Tortorici, 2011, Structure.

Comparative Analysis of the Neurochemical Profile and MAO Inhibition Properties of N-(Furan-2-ylmethyl)-N-methylprop-2-yn-1-amine.

Yagamare Fall, José Marco-Contelles, P. De Deurwaerdère, 2017, ACS chemical neuroscience.

Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders

Andrea Mattevi, A. Mattevi, D. Edmondson, 2002, Nature Structural Biology.

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1.

Maria Paola Costi, S. Cole, L. Chiarelli, 2015, ACS chemical biology.

Cross-talk and ammonia channeling between active centers in the unexpected domain arrangement of glutamate synthase.

A. Mattevi, S. Wakatsuki, A. Coda, 2000, Structure.

The [2Fe–2S] Ferredoxins

G. Zanetti, A. Aliverti, C. Binda, 2011 .

4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity.

J. Mckinney, L. Chiarelli, N. Dhar, 2014, Journal of medicinal chemistry.

Potentiation of Ligand Binding through Cooperative Effects in Monoamine Oxidase B*

A. Mattevi, A. Holt, D. Edmondson, 2010, The Journal of Biological Chemistry.

Inactivation of purified human recombinant monoamine oxidases A and B by rasagiline and its analogues.

M. Youdim, A. Mattevi, D. Edmondson, 2004, Journal of medicinal chemistry.

Crystallographic snapshots of UDP-glucuronic acid 4-epimerase ligand binding, rotation, and reduction

B. Nidetzky, A. Mattevi, L. G. Iacovino, 2020, The Journal of Biological Chemistry.

Structure of the human mitochondrial monoamine oxidase B

A. Mattevi, D. Edmondson, N. Castagnoli, 2006, Neurology.

Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B.

Andrea Mattevi, A. Mattevi, D. Edmondson, 2008, Journal of medicinal chemistry.

Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Anti-Diabetes Drugs.

Andrea Mattevi, Werner J Geldenhuys, W. Geldenhuys, 2012, ACS medicinal chemistry letters.

Stereoselective Activity of 1-Propargyl-4-styrylpiperidine-like Analogues That Can Discriminate between Monoamine Oxidase Isoforms A and B

Janez Konc, J. Kos, I. Mangialavori, 2020, Journal of medicinal chemistry.

Two tyrosine residues, Tyr-108 and Tyr-503, are responsible for the deprotonation of phenolic substrates in vanillyl-alcohol oxidase

M. Fraaije, A. Mattevi, W. V. van Berkel, 2017, The Journal of Biological Chemistry.

Structure of the mutant E92K of [2Fe-2S] ferredoxin I from Spinacia oleracea at 1.7 A resolution.

A Coda, G. Zanetti, A. Mattevi, 1998, Acta crystallographica. Section D, Biological crystallography.

Bioisosteric replacement based on 1,2,4-oxadiazoles in the discovery of 1H-indazole-bearing neuroprotective MAO B inhibitors.

A. Linusson, G. Mangiatordi, T. Latronico, 2023, European journal of medicinal chemistry.

Primary neoplasms of the small bowel at CT: a pictorial essay for the clinician.

A. Gasbarrini, L. Larosa, F. Scaldaferri, 2018, European review for medical and pharmacological sciences.

University of Groningen Structure-based engineering of Phanerochaete chrysosporium alcohol oxidase for enhanced oxidative power towards glycerol

M. Fraaije, A. Mattevi, W. Dijkman, 2018 .

Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Antidiabetes Drugs

W. Geldenhuys, M. Tortorici, A. Mattevi, 2011 .

Monoamine Oxidases.

C. Binda, Dale E. Edmondson, 2018, Sub-cellular biochemistry.

The multipurpose family of flavoprotein oxidases.

M. Fraaije, A. Mattevi, C. Binda, 2020, The Enzymes.

Biocatalytic Properties and Structural Analysis of Eugenol Oxidase from Rhodococcus jostii RHA1: A Versatile Oxidative Biocatalyst

M. Fraaije, A. Mattevi, Ana Rioz‐Martínez, 2016, Chembiochem : a European journal of chemical biology.

Structure-Based Enzyme Tailoring of 5-Hydroxymethylfurfural Oxidase

M. Fraaije, A. Mattevi, W. Dijkman, 2015 .

Structure-Based Engineering of Phanerochaete chrysosporium Alcohol Oxidase for Enhanced Oxidative Power toward Glycerol

M. Fraaije, A. Mattevi, W. Dijkman, 2018, Biochemistry.

Promising Non-cytotoxic Monosubstituted Chalcones to Target Monoamine Oxidase-B

G. Rastelli, M. Christodoulou, D. Passarella, 2021, ACS medicinal chemistry letters.

An Unprecedented NADPH Domain Conformation in Lysine Monooxygenase NbtG Provides Insights into Uncoupling of Oxygen Consumption from Substrate Hydroxylation*

P. Sobrado, A. Mattevi, H. Robinson, 2015, The Journal of Biological Chemistry.

1 STRUCTURAL BASIS OF LSD 1-CoREST SELECTIVITY IN HISTONE H 3 RECOGNITION

F. Forneris, A. Mattevi, A. Adamo, 2007 .

Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B.

A. Mattevi, D. Edmondson, I. McDonald, 2008, Journal of medicinal chemistry.

LSD1: oxidative chemistry for multifaceted functions in chromatin regulation.

F. Forneris, A. Mattevi, E. Battaglioli, 2008, Trends in biochemical sciences.

Discovery and structural characterization of a thermostable bacterial monoamine oxidase.

C. Binda, Lars L Santema, M. Fraaije, 2023, The FEBS journal.