D. Cortright

发表

Pyrido[2,3-b]pyrazines, discovery of TRPV1 antagonists with reduced potential for the formation of reactive metabolites.

S. Boyce, J. Krause, Xiaozhang Zheng, 2010, Bioorganic & medicinal chemistry letters.

Leukocyte effects of C5a-receptor blockade during simulated extracorporeal circulation.

B. Smith, J. Krause, R. Brodbeck, 2007, The Annals of thoracic surgery.

New frontiers in assessing pain and analgesia in laboratory animals

D. Matson, D. Cortright, D. C. Broom, 2008, Expert opinion on drug discovery.

Isolation and Characterization of the Rat Corticotropin-Releasing Hormone (CRH)-Binding Protein Gene: Transcriptional Regulation by Cyclic Adenosine Monophosphate and CRH.

A. Seasholtz, K. Goosens, D. Cortright, 1997, Endocrinology.

C5a, But Not C3a, Increases VEGF Secretion in ARPE-19 Human Retinal Pigment Epithelial Cells

J. Krause, B. Chenard, R. Meade, 2009, Current eye research.

Identification and Characterization of NDT 9513727 [N,N-bis(1,3-Benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl-1H-imidazole-5-methanamine], a Novel, Orally Bioavailable C5a Receptor Inverse Agonist

J. Krause, M. E. Buck, R. Brodbeck, 2008, Journal of Pharmacology and Experimental Therapeutics.

Substance P and neurokinin-1 receptor expression by intrinsic airway neurons in the rat.

S. Shapiro, B. Mora, J. Krause, 2000, American journal of physiology. Lung cellular and molecular physiology.

Transient receptor potential ion channels as targets for the discovery of pain therapeutics.

J. Krause, B. Chenard, D. Cortright, 2005, Current opinion in investigational drugs.

Characterization of N-(Adamantan-1-ylmethyl)-5-[(3R-aminopyrrolidin-1-yl)methyl]-2-chloro-benzamide, a P2X7 Antagonist in Animal Models of Pain and Inflammation

J. Krause, M. E. Buck, Weifeng Yu, 2008, Journal of Pharmacology and Experimental Therapeutics.

Identification and characterization of NDT 9513727, a novel, orally bioavailable C5a receptor inverse agonist

J. Krause, M. E. Buck, R. Brodbeck, 2008 .

Locomotor activity in a novel environment as a test of inflammatory pain in rats.

D. Matson, D. Cortright, D. C. Broom, 2010, Methods in molecular biology.

Biochemical characterization and expression analysis of the Xenopus laevis corticotropin-releasing hormone binding protein

A. Seasholtz, R. Valverde, R. Denver, 2001, Molecular and Cellular Endocrinology.

Formalin- or adjuvant-induced peripheral inflammation increases neurokinin-1 receptor gene expression in the mouse

K. McCarson, D. Cortright, Amy L. Allen, 2003, Brain Research.

Regulation of Pituitary Corticotropin-Releasing Hormone-Binding Protein Messenger Ribonucleic Acid Levels by Restraint Stress and Adrenalectomy* *This work is supported by National Institutes of Health Grant DK-42730 (to A.F.S) and by a Young Investigator Award (to A.F.S.) from the National Alliance

A. Seasholtz, D. Cortright, S. McClennen, 1998, Endocrinology.

From arylureas to biarylamides to aminoquinazolines: discovery of a novel, potent TRPV1 antagonist.

J. Chandrasekhar, S. De Lombaert, Xiaozhang Zheng, 2006, Bioorganic & medicinal chemistry letters.

Aminoquinazolines as TRPV1 antagonists: modulation of drug-like properties through the exploration of 2-position substitution.

Mark T. Kershaw, J. Chandrasekhar, J. Krause, 2008, Bioorganic & medicinal chemistry letters.

Biochemical pharmacology of the vanilloid receptor TRPV1

A. Szallasi, D. Cortright, 2004 .

Discovery of novel 6,6-heterocycles as transient receptor potential vanilloid (TRPV1) antagonists.

Mark T. Kershaw, S. Boyce, J. Krause, 2010, Journal of medicinal chemistry.

The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept

A. Szallasi, Arpad Szallasi, S. R. Eid, 2007, Nature Reviews Drug Discovery.

Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human.

P. Blumberg, A. Szallasi, É. Mezey, 2000, Proceedings of the National Academy of Sciences of the United States of America.

TRP channels and pain.

A. Szallasi, Arpad Szallasi, Daniel N Cortright, 2009, Current pharmaceutical design.

A. Seasholtz, D. Cortright, S. McClennen, 1998, Endocrinology.

Excitatory monocyte chemoattractant protein-1 signaling is up-regulated in sensory neurons after chronic compression of the dorsal root ganglion.

R. LaMotte, Richard J. Miller, Chao Ma, 2005, Proceedings of the National Academy of Sciences of the United States of America.

TRP channels and pain.

J. Krause, Daniel N Cortright, James E Krause, 2007, Biochimica et biophysica acta.

Inflammation-Induced Reduction of Spontaneous Activity by Adjuvant: A Novel Model to Study the Effect of Analgesics in Rats

J. Kehne, D. Matson, D. Cortright, 2007, Journal of Pharmacology and Experimental Therapeutics.

Molecular and biochemical characterization of the mouse brain corticotropin-releasing hormone-binding protein

A. Seasholtz, D. Cortright, A. Nicoletti, 1995, Molecular and Cellular Endocrinology.

The distribution and regulation of vanilloid receptor VR1 and VR1 5′ splice variant RNA expression in rat

J. Krause, D. Cortright, J. F. Sanchez, 2001, Neuroscience.

The Role of the Vanilloid and Related Receptors in Nociceptor Function and Neuroimmune Regulation

A. Szallasi, D. Cortright, 2009 .

The cloned rat vanilloid receptor VR1 mediates both R-type binding and C-type calcium response in dorsal root ganglion neurons.

P. Blumberg, A. Szallasi, J. Krause, 1999, Molecular pharmacology.

Transient receptor potential channels on sensory nerves.

S. R. Eid, D. Cortright, 2009, Handbook of experimental pharmacology.

The tissue distribution and functional characterization of human VR1.

J. Krause, G. White, T. Zou, 2001, Biochemical and biophysical research communications.

Resiniferatoxin‐type phorboid vanilloids display capsaicin‐like selectivity at native vanilloid receptors on rat DRG neurons and at the cloned vanilloid receptor VR1

P. Blumberg, T. Bíró, A. Szallasi, 1999, British journal of pharmacology.

Biochemical pharmacology of the vanilloid receptor TRPV1. An update.

A. Szallasi, D. Cortright, 2004, European journal of biochemistry.

Isolation and characterization of the rat corticotropin-releasing hormone (CRH)-binding protein gene: transcriptional regulation by cyclic adenosine monophosphate and CRH.

A. Seasholtz, D. Cortright, J. Lesh, 1997, Endocrinology.

Hunting for ion channel modulators with herpes simplex virus

J. Krause, M. E. Buck, D. Cortright, 2007, Nature Methods.

Regulation of pituitary corticotropin-releasing hormone-binding protein messenger ribonucleic acid levels by restraint stress and adrenalectomy.

A. Seasholtz, D. Cortright, S. McClennen, 1998, Endocrinology.

Increased TRPA1, TRPM8, and TRPV2 expression in dorsal root ganglia by nerve injury.

M. E. Buck, D. Matson, D. Cortright, 2007, Biochemical and biophysical research communications.

Pyrido[2,3-b]pyrazines, discovery of TRPV1 antagonists with reduced potential for the formation of reactive metabolites.

S. Boyce, J. Krause, Xiaozhang Zheng, 2010, Bioorganic & medicinal chemistry letters.