I. Shytaj

发表

A Highly Intensified ART Regimen Induces Long-Term Viral Suppression and Restriction of the Viral Reservoir in a Simian AIDS Model

A. Della Corte, Mark G. Lewis, E. Acosta, 2012, PLoS pathogens.

Two-Year Follow-Up of Macaques Developing Intermittent Control of the Human Immunodeficiency Virus Homolog Simian Immunodeficiency Virus SIVmac251 in the Chronic Phase of Infection

M. Biffoni, D. Montefiori, E. Arts, 2015, Journal of Virology.

Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress

Ashutosh Kumar Singh, S. Bicciato, M. Forcato, 2020, bioRxiv.

Pharmacologic topoisomerase-I inhibition causes DNA damage and mortality in activated CD4+ T cells

M. Lusic, M. Stanic, I. Shytaj, 2018, Genetics & Applications.

Multifunctional Roles of the N-Terminal Region of HIV-1SF2Nef Are Mediated by Three Independent Protein Interaction Sites

M. Lusic, O. Fackler, Nadine Tibroni, 2019, Journal of Virology.

The FDA-Approved Drug Cobicistat Synergizes with Remdesivir To Inhibit SARS-CoV-2 Replication In Vitro and Decreases Viral Titers and Disease Progression in Syrian Hamsters

A. Gruber, R. Bartenschlager, P. Chlanda, 2022, mBio.

Progress, pitfalls, and path forward of drug repurposing for COVID-19 treatment

Mohamed Alfateh Badawy, M. Elhefnawi, I. Shytaj, 2022, Therapeutic advances in respiratory disease.

Chloroquine and beyond: exploring anti-rheumatic drugs to reduce immune hyperactivation in HIV/AIDS

A. Savarino, I. Shytaj, 2015, Retrovirology.

The FDA-approved drug cobicistat synergizes with remdesivir to inhibit SARS-CoV-2 replication

R. Bartenschlager, P. Chlanda, S. Boulant, 2021, bioRxiv.

Custommune: a web tool to design personalized and population-targeted vaccine epitopes

M. Elhefnawi, A. Savarino, M. Tarek, 2020, medRxiv.

Glycolysis downregulation is a hallmark of HIV‐1 latency and sensitizes infected cells to oxidative stress

J. Karn, S. Bicciato, M. Forcato, 2021, EMBO molecular medicine.

Genomic profiling of HIV-1 integration in microglia cells links viral integration to the topologically associated domains.

J. Karn, K. Vlahovicek, C. Herrmann, 2023, Cell reports.

Genomic profiling of HIV-1 integration in microglia links viral insertions to TAD organization

K. Vlahovicek, C. Herrmann, B. Lucic, 2022, bioRxiv.

Cell‐mediated anti‐Gag immunity in pharmacologically induced functional cure of simian AIDS: a ‘bottleneck effect’?

A. Savarino, I. Shytaj, 2015, Journal of medical primatology.

A cure for AIDS: a matter of timing?

A. Savarino, I. Shytaj, 2013, Retrovirology.

Immunogenicity of personalized dendritic-cell therapy in HIV-1 infected individuals under suppressive antiretroviral treatment: interim analysis from a phase II clinical trial

M. Juliano, R. Salomão, R. Diaz, 2022, AIDS Research and Therapy.

Immunogenicity of personalized dendritic-cell therapy in HIV-1 infected individuals under suppressive antiretroviral treatment: interim analysis from a phase II clinical trial

M. Juliano, R. Salomão, R. Diaz, 2021, AIDS Research and Therapy.

Critical Role of IRF-8 in Negative Regulation of TLR3 Expression by Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase-2 Activity in Human Myeloid Dendritic Cells

M. Rehli, K. Ozato, H. Lawrence, 2011, The Journal of Immunology.

NHC-gold compounds mediate immune suppression through induction of AHR-TGFβ1 signalling in vitro and in scurfy mice

S. Wölfl, J. Hoheisel, Andrea S Bauer, 2020, Communications Biology.

Potential impact of the antirheumatic agent auranofin on proviral HIV-1 DNA in individuals under intensified antiretroviral therapy: results from a randomized clinical trial.

M. Lusic, O. Fackler, R. Diaz, 2019, International journal of antimicrobial agents.

Alterations of redox and iron metabolism accompany the development of HIV latency

S. Bicciato, J. Billingsley, M. Forcato, 2020, The EMBO journal.

Dual targeting of the thioredoxin and glutathione systems in cancer and HIV.

J. Stamler, M. Benhar, A. Savarino, 2016, The Journal of clinical investigation.

Patient-derived HIV-1 Nef alleles reveal uncoupling of CD4 downregulation and SERINC5 antagonism functions of the viral pathogenesis factor.

M. Lusic, O. Fackler, Nadine Tibroni, 2020, Journal of acquired immune deficiency syndromes.

Investigational treatment suspension and enhanced cell-mediated immunity at rebound followed by drug-free remission of simian AIDS

L. Lopalco, D. Montefiori, A. Palamara, 2013, Retrovirology.

A candidate anti-HIV reservoir compound, auranofin, exerts a selective ‘anti-memory' effect by exploiting the baseline oxidative status of lymphocytes

L. Liotta, E. Petricoin, A. Palamara, 2013, Cell Death and Disease.

Investigational treatment suspension and enhanced cell-mediated immunity at rebound followed by drug-free remission of simian AIDS

L. Lopalco, D. Montefiori, A. Palamara, 2013, Retrovirology.

Chloroquine and beyond: exploring anti-rheumatic drugs to reduce immune hyperactivation in HIV/AIDS

A. Savarino, I. Shytaj, 2015, Retrovirology.

A scalable workflow to test “shock and kill” therapeutic approaches against the HIV-1 latent reservoir in blood cells ex vivo

F. Procopio, A. Savarino, I. Shytaj, 2023, STAR Protocols.

Alterations of redox and iron metabolism accompany development of HIV latency

S. Bicciato, J. Billingsley, M. Forcato, 2019, bioRxiv.

NHC-gold compounds mediate immune suppression through induction of AHR-TGFÎ21 signalling in vitro and in scurfy mice

S. Wölfl, J. Hoheisel, Andrea S Bauer, 2019 .

Broad-spectrum antiviral activity of two structurally analogous CYP3A inhibitors against pathogenic human coronaviruses in vitro.

I. Shytaj, J.-M. Bazire, Lara Gallucci, 2023, Antiviral research.

Manuscript title: Genomic profiling of HIV-1 integration in microglia links viral insertions to TAD organization

C. Herrmann, M. Lusic, O. Fackler, 2022 .

Broad-spectrum antiviral activity of clinically approved CYP3A inhibitors against pathogenic human coronaviruses in vitro

A. Davidson, Lara Gallucci, I. Shytaj, 2023, bioRxiv.