C. Hack

发表

Administration of OKT3 as a two-hour infusion attenuates first-dose side effects.

I. T. Ten Berge, F. V. van Diepen, S. Buysmann, 1997, Transplantation.

Pulmonary Secretory Phospholipase A2 in Infants with Respiratory Distress Syndrome Stimulates in vitro Neutrophil Migration

F. Walther, J. Elferink, H. Berger, 2009, Neonatology.

Immunogenicity Assessment of Recombinant Human C1-Inhibitor

M. Mannesse, B. Oortwijn, C. Hack, 2012, BioDrugs.

Immunogenicity assessment of recombinant human c1-inhibitor: an integrated analysis of clinical studies.

M. Mannesse, B. Oortwijn, C. Hack, 2012, BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy.

Early complement components in Alzheimer's disease brains

R. Veerhuis, P. Eikelenboom, C. Hack, 1995, Acta Neuropathologica.

Increased Nox2 expression in human cardiomyocytes after acute myocardial infarction

C. Visser, H. Niessen, C. Meischl, 2003, Journal of clinical pathology.

Apolipoprotein H, a new mediator in the inflammatory changes ensuing in jeopardised human myocardium

L. Aarden, W. Lagrand, C. Meijer, 2000, Journal of clinical pathology.

Intercellular Adhesion Molecule‐1 in the Heart

C. Visser, H. Niessen, P. Krijnen, 2002, Annals of the New York Academy of Sciences.

NAD(P)H oxidase in the failing human heart.

C. Visser, C. Meischl, P. Krijnen, 2003, Journal of the American College of Cardiology.

The Regulation of C1 Activation and Its Role in Disease

C. Hack, 2000 .

Complement Activation by C-Reactive Protein: An Inflammatory Mechanism in Human Disease?

G. Wolbink, W. Lagrand, C. Hack, 1999 .

The Impact of Heparin Coated Circuits Upon Metabolism in Vital Organs: Effect Upon Cerebral and Renal Function During and After Cardiopulmonary Bypass

W. van Oeveren, L. Eijsman, G. V. van Kamp, 2005, ASAIO journal.

C‐reactive protein levels in hereditary angioedema

C. Hack, A. Relan, Z. Hofman, 2014, Clinical and experimental immunology.

Role and regulation of early complement activation products in Alzheimer’s disease

R. Veerhuis, P. Eikelenboom, F. L. Muiswinkel, 2001 .

Disruption of the internal thioester bond in the third component of complement (C3) results in the exposure of neodeterminants also present on activation products of C3. An analysis with monoclonal antibodies.

A. Eerenberg, J. Nuijens, J. Abbink, 1988, Journal of immunology.

Elevated D-dimers in attacks of hereditary angioedema are not associated with increased thrombotic risk

H. Longhurst, A. Reshef, A. Zanichelli, 2015, Allergy.

Activated human PMN synthesize and release a strongly fucosylated glycoform of α1‐acid glycoprotein, which is transiently deposited in human myocardial infarction

J. Calafat, W. van Dijk, H. Niessen, 2005, Journal of leukocyte biology.

Soluble CD59 is a Novel Biomarker for the Prediction of Obstructive Chronic Lung Allograft Dysfunction After Lung Transplantation

J. Grutters, H. Otten, J. K. Kwakkel-van Erp, 2016, Scientific Reports.

Toxicity of OKT 3 increases with dosage: a controlled study in renal transplant recipients

F. Bemelman, S. Yong, P. Schellekens, 1995 .

Toxicity of OKT 3 increases with dosage: a controlled study in renal transplant recipients

F. Bemelman, S. Yong, P. Schellekens, 1995, Transplant international : official journal of the European Society for Organ Transplantation.

C-reactive protein and the risk of cardiovascular mortality.

H. Niessen, C. Hack, 2003, The American journal of medicine.

N(omega)-(carboxymethyl)lysine depositions in human aortic heart valves: similarities with atherosclerotic blood vessels.

C. Schalkwijk, V. V. van Hinsbergh, L. Eijsman, 2004, Atherosclerosis.

Cytokines, coagulation and fibrinolysis

C. Hack, 1999 .

Distribution pattern and functional state of α1-antichymotrypsin in plaques and vascular amyloid in Alzheimer's disease

P. Eikelenboom, F. Stam, J. Abbink, 1991, Acta Neuropathologica.

BACE1 activity in cerebrospinal fluid and its relation to markers of AD pathology.

W. M. van der Flier, P. Scheltens, M. Blankenstein, 2010, Journal of Alzheimer's disease : JAD.

Secretory type II phospholipase A2 in culprit coronary lesions is associated with myocardial infarction

C. Visser, M. Meuwissen, J. Piek, 2008, European journal of clinical investigation.

Thymic Stromal Lymphopoietin, a Novel Proinflammatory Mediator in Rheumatoid Arthritis That Potently Activates CD1c+ Myeloid Dendritic Cells to Attract and Stimulate T Cells

F. Lafeber, T. Radstake, C. Hack, 2014, Arthritis & rheumatology.

Intra-articular CD1c-expressing myeloid dendritic cells from rheumatoid arthritis patients express a unique set of T cell-attracting chemokines and spontaneously induce Th1, Th17 and Th2 cell activity

F. Lafeber, T. Radstake, J. V. van Roon, 2013, Arthritis Research & Therapy.

Increased intra-articular granzyme M may trigger local IFN-λ1/IL-29 response in rheumatoid arthritis.

H. M. Kok, M. Boes, N. Bovenschen, 2020, Clinical and experimental rheumatology.

The Additive Inflammatory In Vivo and In Vitro Effects of IL-7 and TSLP in Arthritis Underscore the Therapeutic Rationale for Dual Blockade

F. Lafeber, J. V. van Roon, M. Hillen, 2015, PloS one.

C‐reactive protein and complement depositions in human infarcted myocardium are more extensive in patients with reinfarction or upon treatment with reperfusion

C. Visser, R. Veerhuis, P. Krijnen, 2004, European journal of clinical investigation.

The PROCARE consortium: toward an improved allocation strategy for kidney allografts.

M. Bots, J. D. de Fijter, F. V. van Ittersum, 2014, Transplant immunology.

Anti-BPIFA1/SPLUNC1: a new autoantibody prevalent in patients with endstage cystic fibrosis.

H. Otten, E. A. van de Graaf, K. Budding, 2014, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Insect-sting challenge in 324 subjects with a previous anaphylactic reaction: current criteria for insect-venom hypersensitivity do not predict the occurrence and the severity of anaphylaxis.

V. Zwan, J. van der Zwan, V. Linden, 1994, The Journal of allergy and clinical immunology.

Controlled insect-sting challenge in 55 patients: correlation between activation of plasminogen and the development of anaphylactic shock.

J. P. de Boer, J. van der Zwan, D. Roem, 1993, Blood.

Activation of the contact system in insect-sting anaphylaxis: association with the development of angioedema and shock.

V. Zwan, A. Eerenberg, J. van der Zwan, 1993, Blood.

Anaphylactic Shock after Insect-Sting Challenge in 138 Persons with a Previous Insect-Sting Reaction

R. Kraaijenhagen, J. van der Zwan, A. Struyvenberg, 1993, Annals of Internal Medicine.

Insect-sting challenge in 138 patients: relation between clinical severity of anaphylaxis and mast cell activation.

J. van der Zwan, Y. Vivié-Kipp, A. Struyvenberg, 1992, The Journal of allergy and clinical immunology.

Preliminary report: complement activation in wasp-sting anaphylaxis

A. Struyvenberg, C. Hack, P. G. V. D. Linden, 1990, The Lancet.

Anti-ETAR and anti-AT1R autoantibodies are elevated in patients with endstage cystic fibrosis.

D. Dragun, H. Otten, J. K. Kwakkel-van Erp, 2015, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

C-reactive protein and natural IgM antibodies are activators of complement in a rat model of intestinal ischemia and reperfusion.

T. V. van Gulik, I. Schoots, H. Niessen, 2007, Surgery.

Continuous 48-h C1-inhibitor treatment, following reperfusion therapy, in patients with acute myocardial infarction.

H. Wellens, W. Hermens, P. Strengers, 2002, European heart journal.

The endothelium in sepsis: Source of and a target for inflammation

S. Zeerleder, C. Hack, 2001, Critical care medicine.

Self-administration of C1-inhibitor concentrate in patients with hereditary or acquired angioedema caused by C1-inhibitor deficiency.

M. Levi, G. Choi, C. Hack, 2006, The Journal of allergy and clinical immunology.

During Human Endotoxemia Mitogen-Activated Protein Kinase Inhibitor Anti-Inflammatory Effects of a p38

S. Deventer, J. Madwed, M. Peppelenbosch, 2002 .

Antibodies against Apoptotic Cells Present in End-stage Lung Disease Patients Do Not Correlate with Clinical Outcome after Lung Transplantation

H. Otten, J. K. Kwakkel-van Erp, E. A. van de Graaf, 2017, Front. Immunol..

C-reactive protein as a cardiovascular risk factor: more than an epiphenomenon?

C. Visser, W. Hermens, G. Wolbink, 1999, Circulation.

Type II secretory phospholipase A2 binds to ischemic flip-flopped cardiomyocytes and subsequently induces cell death.

C. Visser, R. Gottlieb, R. Verheijen, 2003, American journal of physiology. Heart and circulatory physiology.

C-reactive protein as a pro-inflammatory mediator in cardiovascular disease by its ability to activate complement: additional proof and hypothetical mechanisms.

C. Visser, W. Hermens, W. Lagrand, 2002, Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation.

Secretory type II phospholipase A(2) binds to ischemic myocardium during myocardial infarction in humans.

C. Visser, W. Hermens, W. Lagrand, 2002, Cardiovascular research.

Role for complement as an intermediate between C-reactive protein and intercellular adhesion molecule-1 expression?

W. Lagrand, H. Niessen, C. Hack, 2001, Circulation.

CRP, a major culprit in complement-mediated tissue damage in acute myocardial infarction?

C. Visser, W. Lagrand, C. Meijer, 2001, International immunopharmacology.

Upregulation of ICAM-1 on cardiomyocytes in jeopardized human myocardium during infarction.

C. Visser, W. Lagrand, Cees A. Visser, 1999, Cardiovascular research.

Thymic stromal lymphopoietin as a novel mediator amplifying immunopathology in rheumatic disease.

J. V. van Roon, M. Hillen, T. Radstake, 2015, Rheumatology.

Increased Nox 2 expression in human cardiomyocytes after acute myocardial infarction

C. Visser, C. Meischl, P. Krijnen, 2003 .

[Anaphylactic reactions following insect stings: clinical aspects, course and treatment].

A. Struyvenberg, C. Hack, P. V. D. van der Linden, 1994, Nederlands tijdschrift voor geneeskunde.

M. Bots, P. V. D. van der Boog, M. Christiaans, 2018, Front. Immunol..

Cleaved kininogen as a biomarker for bradykinin release in hereditary angioedema.

T. Renné, C. Maas, G. Pasterkamp, 2017, The Journal of allergy and clinical immunology.

Differential effects of donor‐specific HLA antibodies in living versus deceased donor transplant

M. Bots, P. V. D. van der Boog, M. Christiaans, 2018, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Mechanisms of lymphocyte-mediated cytotoxicity in acute renal allograft rejection.

I. T. Ten Berge, M. Daha, P. Wever, 1998, Transplantation.

Human granzyme B mediates cartilage proteoglycan degradation and is expressed at the invasive front of the synovium in rheumatoid arthritis.

H. Ronday, F. Breedveld, P. Tak, 2001, Rheumatology.

Granzyme Activity in the Inflamed Lung Is

Y. Cormier, A. Wolbink, C. Hack, 2000 .

Proteinase Inhibitors Not Controlled by Endogenous Serine Granzyme Activity in the Inflamed Lung Is

Y. Cormier, A. Wolbink, C. Hack, 2000 .

Intrathecal production of interleukin-12 and gamma interferon in patients with bacterial meningitis

W. Hop, R. de Groot, H. Savelkoul, 1997, Infection and immunity.

Development and Validation of a Multiplex Non-HLA Antibody Assay for the Screening of Kidney Transplant Recipients

M. Bots, M. Christiaans, J. D. de Fijter, 2018, Front. Immunol..

Ischemia induces nuclear NOX2 expression in cardiomyocytes and subsequently activates apoptosis

C. Visser, M. Okrój, C. Hack, 2006, Apoptosis.

Increased systemic levels of soluble granzymes A and B during primary cytomegalovirus infection after renal transplantation.

I. T. Ten Berge, A. Wolbink, P. Wever, 1998, Transplantation proceedings.

Inhibition of Rho-ROCK signaling induces apoptotic and non-apoptotic PS exposure in cardiomyocytes via inhibition of flippase.

W. Paulus, C. Stehouwer, V. V. van Hinsbergh, 2010, Journal of molecular and cellular cardiology.

Rituximab-induced elimination of acquired angioedema due to C1-inhibitor deficiency.

M. Levi, M. V. van Oers, C. Hack, 2006, The American journal of medicine.

IgM antibodies against apoptotic cells and phosphorylcholine in patients with acute myocardial infarction in relation to infarct size and inflammatory response.

S. Boekholdt, P. Krijnen, W. Lagrand, 2012, Advances in clinical and experimental medicine : official organ Wroclaw Medical University.

Toward a Sensible Single-antigen Bead Cutoff Based on Kidney Graft Survival

M. Bots, P. V. D. van der Boog, M. Christiaans, 2019, Transplantation.

Genes for peripheral neuropathy and their relevance to clinical practice

P. Scheltens, C. Hack, P. Scheltens, 2004, Journal of Neurology, Neurosurgery & Psychiatry.

Chronic idiopathic and secondary neutropenia: clinical and serological investigations

C. Hack, C. Engelfriet, J. P. van der Veen, 1986, British journal of haematology.

Complement Activation in Relation to Capillary Leakage in Children with Septic Shock and Purpura

W. Hop, J. Hazelzet, A. Eerenberg, 1998, Infection and Immunity.

Complement activation induced by ischemia-reperfusion in humans: a study in patients undergoing partial hepatectomy.

M. Boermeester, W. Frederiks, G. Wolbink, 1998, Journal of hepatology.

Fibrinolysis in Disseminated Intravascular Coagulation

C. Hack, 2001, Seminars in thrombosis and hemostasis.

A modified competitive inhibition radioimmunoassay for the detection of C3a. Use of 125I-C3 instead of 125I-C3a.

L. Thijs, A. Eerenberg, J. Nuijens, 1988, Journal of immunological methods.

Tissue factor pathway of coagulation in sepsis

C. Hack, 2000, Critical care medicine.

Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk.

A. Knulst, H. van Os-Medendorp, E. van Hoffen, 2016, The Journal of allergy and clinical immunology.

A mutation in the kringle domain of human factor XII that causes autoinflammation, disturbs zymogen quiescence, and accelerates activation

C. Maas, M. Maurer, J. Scheffel, 2019, The Journal of Biological Chemistry.

Anti-C2 Antibody ARGX-117 Inhibits Complement in a Disease Model for Multifocal Motor Neuropathy

L. H. van den Berg, R. Pasterkamp, C. Blanchetot, 2021, Neurology: Neuroimmunology & Neuroinflammation.

Decreased expression of thymic stromal lymphopoietin in salivary glands of patients with primary Sjögren’s syndrome is associated with increased disease activity

F. Lafeber, J. V. van Roon, A. Kruize, 2016, Modern rheumatology.

Canine IL4-10 fusion protein provides disease modifying activity in a canine model of OA; an exploratory study

M. Tryfonidou, N. Eijkelkamp, S. Mastbergen, 2019, PloS one.

Cardiovascular secrets of secretory phospholipase A2

C. Hack, H. Niessen, C. Hack, 2002, European journal of clinical investigation.

Biochemical diagnosis of Alzheimer's disease

P. Scheltens, L. Wahlund, P. Bezemer, 2000, Neurobiology of Aging.

Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injury.

P. Doevendans, G. Pasterkamp, T. Woodruff, 2014, Cardiovascular research.

A fusion protein of interleukin‐4 and interleukin‐10 protects against blood‐induced cartilage damage in vitro and in vivo

L. V. van Vulpen, R. Schutgens, S. Mastbergen, 2017, Journal of thrombosis and haemostasis : JTH.

The Coagulation System in Sepsis

C. Hack, 2002 .

Epinephrine Exerts Anticoagulant Effects during Human Endotoxemia

T. van der Poll, S. Lowry, S. Coyle, 1997, The Journal of experimental medicine.

UvA-DARE (Digital Academic Repository) Epinephrine exerts anticoagulant effects during human endotoxemia

S. Lowry, S. Coyle, W. Buurman, 1997 .

Granzyme-positive cytotoxic cells are specifically increased in early rheumatoid synovial tissue.

F. Breedveld, P. Tak, M. Daha, 1994, Arthritis and rheumatism.

C1-esterase inhibitor substitution in sepsis

L. Thijs, A. Ogilvie, B. Eisele, 1992, The Lancet.

Selective expansion of a peripheral blood CD8+ memory T cell subset expressing both granzyme B and L-selectin during primary viral infection in renal allograft recipients.

I. T. Ten Berge, P. Wever, P. Schellekens, 1998, Transplantation proceedings.

Interleukin-7: a key mediator in T cell-driven autoimmunity, inflammation, and tissue destruction.

F. Lafeber, J. V. van Roon, C. Hack, 2012, Current pharmaceutical design.

Immunosafety of Recombinant Human C1-Inhibitor in Hereditary Angioedema: Evaluation of IgE Antibodies

R. Ree, B. Oortwijn, C. Hack, 2013, Clinical Drug Investigation.

Bradykinin: Inflammatory Product of the Coagulation System

C. Maas, C. Hack, S. de Maat, 2016, Clinical Reviews in Allergy & Immunology.

High occurrence of antihistamine resistance in patients with recurrent idiopathic angioedema

C. Maas, A. Knulst, C. Hack, 2019, Clinical and Translational Allergy.

Antibodies against ARHGDIB are associated with long‐term kidney graft loss

M. Bots, M. Christiaans, J. D. de Fijter, 2019, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Angioedema attacks in patients with hereditary angioedema: Local manifestations of a systemic activation process.

S. Zeerleder, C. Drouet, B. Zuraw, 2016, The Journal of allergy and clinical immunology.

Activation of protein C following infusion of protein C concentrate in children with severe meningococcal sepsis and purpura fulminans: a randomized, double-blinded, placebo-controlled, dose-finding study.

P. Mulder, J. Hazelzet, R. de Groot, 2003, Critical care medicine.

IL4‐10 fusion protein: a novel immunoregulatory drug combining activities of interleukin 4 and interleukin 10

N. Eijkelkamp, F. Lafeber, C. Hack, 2018, Clinical and experimental immunology.

Evaluation of intrathecal serum amyloid P (SAP) and C-reactive protein (CRP) synthesis in Alzheimer's disease with the use of index values.

W. M. van der Flier, P. Scheltens, M. Blankenstein, 2011, Journal of Alzheimer's disease : JAD.

The Autoimmune-Associated Single Nucleotide Polymorphism Within PTPN22 Correlates With Clinical Outcome After Lung Transplantation

J. van Setten, H. Otten, J. K. Kwakkel-van Erp, 2019, Front. Immunol..

Circulating nucleosomes and severity of illness in children suffering from meningococcal sepsis treated with protein C

C. Esmon, J. Hazelzet, S. Zeerleder, 2012, Critical care medicine.

Apoptosis in myocardial ischaemia and infarction

C. Visser, H. Niessen, P. Krijnen, 2002, Journal of clinical pathology.

A phase I study of recombinant human C1 inhibitor in asymptomatic patients with hereditary angioedema.

A. Eerenberg, J. Nuijens, J. Burggraaf, 2005, The Journal of allergy and clinical immunology.

Interference of IgG, IgG aggregates and immune complexes in tests for platelet autoantibodies

R. Smeenk, C. Hack, F. Helmerhorst, 1983, British journal of haematology.

Distribution pattern and functional state of alpha 1-antichymotrypsin in plaques and vascular amyloid in Alzheimer's disease. A immunohistochemical study with monoclonal antibodies against native and inactivated alpha 1-antichymotrypsin.

P. Eikelenboom, F. Stam, J. Abbink, 1991, Acta neuropathologica.

Recombinant human C1-inhibitor for the treatment of acute angioedema attacks in patients with hereditary angioedema.

J. Nuijens, M. Cicardi, B. Zuraw, 2010, The Journal of allergy and clinical immunology.

Recombinant human C1‐inhibitor in the treatment of acute angioedema attacks

H. Farkas, M. Soeters, J. Nuijens, 2007, Transfusion.

Hereditary Angioedema Attacks: Local Swelling at Multiple Sites

C. Hack, A. Relan, Z. Hofman, 2016, Clinical Reviews in Allergy & Immunology.

Clinical impact of peripheral attacks in hereditary angioedema patients.

A. Knulst, J. Nuijens, M. Cicardi, 2012, The American journal of medicine.

Target levels of functional C1‐inhibitor in hereditary angioedema

M. Cicardi, C. Hack, A. Relan, 2012, Allergy.

Recombinant C1-Inhibitor

E. S. Amersfoort, J. Meijers, K. Bakhtiari, 2012, BioDrugs.

Clinical Studies of Recombinant Human C1 Inhibitor (rhC1INH) in Patients with Acute Attacks of Hereditary Angioedema

H. Farkas, J. Nuijens, M. Cicardi, 2008 .

Generation of plasmin during acute attacks of hereditary angioedema.

A. Eerenberg, J. P. de Boer, M. Cicardi, 1993, The Journal of laboratory and clinical medicine.

C1-inhibitor: antigenic and functional analysis.

C. Hack, 2000, Methods in molecular biology.

Complement-Mediated Ischemia-Reperfusion Injury: Lessons Learned From Animal and Clinical Studies

T. V. van Gulik, C. Hack, G. Diepenhorst, 2009, Annals of surgery.

Detecting oral kallikrein-targeting therapy through triggered contact activation: a phase I study.

C. Maas, C. Hack, S. de Maat, 2020, The Journal of allergy and clinical immunology.

Evidence for bradykinin release in chronic spontaneous urticaria

C. Maas, A. Knulst, C. Hack, 2020, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Studies on the Contact System of Coagulation during Therapy with High Doses of Recombinant IL-2: Implications for Septic Shock

L. Thijs, R. S. V. STRACK VAN SCHIJNDEL, A. Eerenberg, 1991, Thrombosis and Haemostasis.

Targeting Complement in Rheumatoid Arthritis

P. Tak, R. Nieuwland, C. Hack, 2008 .

Raised granzyme B levels are associated with erosions in patients with early rheumatoid factor positive rheumatoid arthritis

P. Tak, R. Wesley, R. Goldbach-Mansky, 2004, Annals of the rheumatic diseases.

Complement C1-inhibitor expression in Alzheimer’s disease

R. Veerhuis, P. Eikelenboom, J. Hoozemans, 1998, Acta Neuropathologica.

Serum inflammatory proteins and cognitive decline in older persons

J. Smit, C. Jonker, C. Jonker, 2005, Neurology.

A role for secretory phospholipase A2 and C-reactive protein in the removal of injured cells.

C. Schalkwijk, W. Hermens, G. Wolbink, 1997, Immunology today.

Allocation to highly sensitized patients based on acceptable mismatches results in low rejection rates comparable to nonsensitized patients

M. Bots, M. Christiaans, D. Roelen, 2019, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Expression of granzymes A and B in synovial tissue from patients with rheumatoid arthritis and osteoarthritis.

F. Breedveld, P. Tak, B. Brinkman, 1994, Clinical immunology and immunopathology.

Effect of initial immunosuppression on long-term kidney transplant outcome in immunological low-risk patients.

M. Bots, P. V. D. van der Boog, M. Christiaans, 2018, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Increased numbers of granzyme-B-expressing cytotoxic T-lymphocytes in the small intestine of HIV-infected patients.

S. Danner, P. Wever, C. Hack, 1996, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

Expression of granzyme B during primary cytomegalovirus infection after renal transplantation.

C. Hack, A. Wolbink, P. Wever, 1999, The Journal of infectious diseases.

C-reactive protein colocalizes with complement in human hearts during acute myocardial infarction.

C. Visser, G. Wolbink, W. Lagrand, 1997, Circulation.

Contribution of interleukin-1 to activation of coagulation and fibrinolysis, neutrophil degranulation, and the release of secretory-type phospholipase A2 in sepsis: studies in nonhuman primates after interleukin-1 alpha administration and during lethal bacteremia

M. Boermeester, L. Moldawer, S. Lowry, 1995 .

Complement activation in amyloid plaques in Alzheimer’s dementia

P. Eikelenboom, F. Stam, C. Hack, 1988, Virchows Archiv. B, Cell pathology including molecular pathology.

CSF levels of PSA and PSA–ACT complexes in Alzheimer's disease

P. Scheltens, M. Blankenstein, R. Veerhuis, 2009, Annals of clinical biochemistry.

Immunoglobulin M, C-Reactive Protein and Complement Activation in Rat Hepatic Ischemia-Reperfusion Injury

T. V. van Gulik, H. Niessen, C. Hack, 2014, European Surgical Research.

HUMAN C-REACTIVE PROTEIN BINDS TO MURINE APOPTOTIC CELLS WITHOUT ENHANCING INJURY IN IN A MURINE INTESTINAL ISCHEMIA-REPERFUSION MODEL 5

T. M. Gulik, R. Aalberse, H. Niessen, 2014 .

Inflammatory markers in late-life depression: results from a population-based study.

A. Beekman, B. Penninx, D. Deeg, 2008, Journal of affective disorders.

Increased levels of sTNF receptors following OKT3 treatment.

T. van der Poll, F. Bemelman, S. V. van Deventer, 1994, Transplantation Proceedings.

Nϵ-(Carboxymethyl)lysine Depositions in Intramyocardial Blood Vessels in Human and Rat Acute Myocardial Infarction: A Predictor or Reflection of Infarction?

C. Visser, C. Schalkwijk, V. V. van Hinsbergh, 2006, Arteriosclerosis, thrombosis, and vascular biology.

Inflammatory markers in AD and MCI patients with different biomarker profiles

P. Scheltens, A. Schuitemaker, C. Jonker, 2009, Neurobiology of Aging.

Clusterin: a protective mediator for ischemic cardiomyocytes?

C. Visser, H. Niessen, P. Krijnen, 2005, American journal of physiology. Heart and circulatory physiology.

Inhibition of type 2A secretory phospholipase A2 reduces death of cardiomyocytes in acute myocardial infarction

W. Paulus, H. Niessen, P. Krijnen, 2009, Apoptosis.

Inhibition of type 2 A secretory phospholipase A 2 reduces death of cardiomyocytes in acute myocardial infarction

W. Paulus, H. Niessen, P. Krijnen, 2009 .

IgM colocalises with complement and C reactive protein in infarcted human myocardium

C. Visser, P. Krijnen, T. Cramer, 2005, Journal of Clinical Pathology.

C-reactive protein activates complement in infarcted human myocardium.

C. Visser, W. Lagrand, Y. Lubbers, 2003, The American journal of pathology.

Letter by Krijnen et al regarding article, "The sPLA2 Inhibition to Decrease Enzyme Release after Percutaneous Coronary Intervention (SPIDER-PCI) trial".

H. Niessen, P. Krijnen, C. Hack, 2011, Circulation.

A Promoter Polymorphism in the CD59 Complement Regulatory Protein Gene in Donor Lungs Correlates With a Higher Risk for Chronic Rejection After Lung Transplantation

H. Otten, J. K. Kwakkel-van Erp, K. Budding, 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Pretransplant C3d-Fixing Donor-Specific Anti-HLA Antibodies Are Not Associated with Increased Risk for Kidney Graft Failure.

M. Bots, P. V. D. van der Boog, M. Christiaans, 2018, Journal of the American Society of Nephrology : JASN.

Association between a Single Donor TARC/CCL17 Promotor Polymorphism and Obstructive Chronic Lung Allograft Dysfunction after Lung Transplantation

J. van Setten, H. Otten, E. A. van de Graaf, 2017, Front. Immunol..

CSF Neurofilaments in Frontotemporal Dementia Compared with Early Onset Alzheimer’s Disease and Controls

P. Scheltens, Y. Pijnenburg, N. Schoonenboom, 2007, Dementia and Geriatric Cognitive Disorders.

P. Scheltens, L. Wahlund, S. Schoonenboom, 2002, Journal of Neural Transmission.

Activation of Coagulation and Fibrinolysis Following OKT3 Administration to Renal Transplant Recipients: Association with Distinct Mediators

M. Raasveld, C. Hack, I. T. ten Berge, 1992, Thrombosis and Haemostasis.

Thromboembolic complications and dose of monoclonal OKT3 antibody

M. Raasveld, C. Hack, S. Surachno, 1992, The Lancet.

C-reactive protein co-localizes with complement in human hearts during acute myocardial infarction

C. Visser, G. Wolbink, W. Lagrand, 1996 .

Pharmacokinetics of C1‐inhibitor protein in patients with acute myocardial infarction

P. Hemker, W. Hermens, W. Lagrand, 2002, Clinical pharmacology and therapeutics.

Safety of C1-inhibitor for clinical use.

W. Hermens, C. Hack, C. de Zwaan, 2002, Circulation.

A paired kidney analysis on the impact of pre-transplant anti-HLA antibodies on graft survival.

M. Bots, P. V. D. van der Boog, M. Christiaans, 2018, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Apoptotic tubular cell death during acute renal allograft rejection.

J. Weening, P. Wever, J. Aten, 1998, Clinical nephrology.

Inhibition of sPLA2-IIA, C-reactive protein or complement: new therapy for patients with acute myocardial infarction?

C. Visser, C. Meischl, P. Krijnen, 2006, Cardiovascular & hematological disorders drug targets.

Demonstration in human plasma of a form of C3 that has the conformation of "C3b-like C3".

F. V. van Milligen, C. Hack, J. Paardekooper, 1990, Journal of immunology.

Distribution pattern and functional state of complement proteins and alpha 1-antichymotrypsin in cerebral beta/A4 deposits in Alzheimer's disease.

W. Kamphorst, P. Eikelenboom, C. Hack, 1992, Research in immunology.

Serum Amyloid P Component as a Biomarker in Mild Cognitive Impairment and Alzheimer’s Disease

W. M. van der Flier, P. Scheltens, A. Schuitemaker, 2008, Dementia and Geriatric Cognitive Disorders.

H9c2 cardiomyoblasts produce thyroid hormone.

W. Paulus, H. Buermans, M. Blankenstein, 2008, American journal of physiology. Cell physiology.

H 9 c 2 cardiomyoblasts produce thyroid hormone

W. Paulus, H. Buermans, M. Blankenstein, 2008 .

Localisation of C reactive protein in infarcted tissue sites of multiple organs during sepsis.

W. Lagrand, H. Niessen, A. Baidoshvili, 2002, Journal of clinical pathology.

Cellular origin and procoagulant properties of microparticles in meningococcal sepsis.

R. Westendorp, C. Hack, R. Nieuwland, 2000, Blood.

Recombinant human antithrombin III improves survival and attenuates inflammatory responses in baboons lethally challenged with Escherichia coli.

C. Hack, P. Jansen, A. Chang, 2000, Blood.

Human mast cells produce and release the cytotoxic lymphocyte associated protease granzyme B upon activation.

C. Hack, M. Kleijmeer, A. Wolbink, 2007, Molecular immunology.

IL4-10 fusion protein has chondroprotective, anti-inflammatory and potentially analgesic effects in the treatment of osteoarthritis.

M. Tryfonidou, C. Hack, N. Eijkelkamp, 2018, Osteoarthritis and cartilage.

Role of cytokines in sepsis.

C. Hack, L. Thijs, L. Aarden, 1997, Advances in immunology.

Interference of Wegener's granulomatosis autoantibodies with neutrophil Proteinase 3 activity

A. Borne, C. Hack, R. Goldschmeding, 1992, Clinical and experimental immunology.

Tissue factor pathway inhibitor dose-dependently inhibits coagulation activation without influencing the fibrinolytic and cytokine response during human endotoxemia.

T. van der Poll, E. de Jonge, C. Hack, 2000, Blood.

Activation of coagulation after administration of tumor necrosis factor to normal subjects.

T. van der Poll, H. Büller, J. T. ten Cate, 1990, The New England journal of medicine.

Cerebral and Hepatic Inflammatory Response after Neonatal Hypoxia-Ischemia in Newborn Rats

C. Hack, A. Kavelaars, Cindy T. J. van Velthoven, 2013, Developmental Neuroscience.

Elevated levels of total and dengue virus‐specific immunoglobulin E in patients with varying disease severity

Wiley Interscience, A. Osterhaus, C. Hack, 2003, Journal of medical virology.

Prediction of mortality in febrile medical patients: How useful are systemic inflammatory response syndrome and sepsis criteria?

C. Hack, A. Groeneveld, L. Thijs, 1998, Chest.

Granzymes Regulate Proinflammatory Cytokine Responses

C. Hack, N. Bovenschen, A. Wensink, 2015, The Journal of Immunology.

Targeting Complement in Rheumatoid Arthritis

P. Tak, R. Nieuwland, C. Hack, 2008 .

CRP-mediated activation of complement in vivo: assessment by measuring circulating complement-C-reactive protein complexes.

I. T. Ten Berge, C. Hack, G. Wolbink, 1996, Journal of immunology.

Expression of granzyme A and B proteins by cytotoxic lymphocytes involved in acute renal allograft rejection.

I. T. Ten Berge, C. Hack, J. Weening, 1995, Kidney international.

Serine proteases of the human immune system in health and disease.

I. T. Ten Berge, C. Hack, J. Hamann, 2010, Molecular immunology.

Intracellular serpin SERPINB6 (PI6) is abundantly expressed by human mast cells and forms complexes with beta-tryptase monomers.

C. Hack, A. Wolbink, I. S. van Houdt, 2004, Blood.

Infliximab treatment reduces complement activation in patients with rheumatoid arthritis

J. Twisk, A. Familian, C. Hack, 2005, Annals of the rheumatic diseases.

Quantification of amyloid-beta 40 in cerebrospinal fluid.

P. Scheltens, J. Wiltfang, M. Blankenstein, 2009, Journal of immunological methods.

Effects of interferon‐alpha (IFN‐α) administration on leucocytes in healthy humans

J. Romijn, C. Hack, R. Heijligenberg, 1997, Clinical and experimental immunology.

How can we reduce costs of solid‐phase multiplex‐bead assays used to determine anti‐HLA antibodies?

M. Bots, P. V. D. van der Boog, M. Christiaans, 2016, HLA.

ARGX-117, a therapeutic complement inhibiting antibody targeting C2

L. Boon, C. Hack, C. Blanchetot, 2020, Journal of Allergy and Clinical Immunology.

Genes for peripheral neuropathy and their relevance to clinical practice

P. Scheltens, B. Norrving, C. Hack, 2004, Journal of Neurology, Neurosurgery & Psychiatry.

Plasminogen activator and plasminogen activator inhibitor I release during experimental endotoxaemia in chimpanzees: effect of interventions in the cytokine and coagulation cascades.

T. van der Poll, H. Büller, J. T. ten Cate, 1995, Clinical science.

Platelet-activating factor antagonist TCV-309 attenuates the induction of the cytokine network in experimental endotoxemia in chimpanzees.

T. van der Poll, J. T. ten Cate, S. Deventer, 1994, Journal of immunology.

Expression levels of apoptosis-related proteins predict clinical outcome in anaplastic large cell lymphoma.

C. Meijer, C. Hack, G. Ossenkoppele, 2002, Blood.

ADAMTS‐13, von Willebrand factor and related parameters in severe sepsis and septic shock

B. Lämmle, P. Reitsma, C. Hack, 2007, Journal of thrombosis and haemostasis : JTH.

Granzyme B, a novel mediator of allergic inflammation: its induction and release in blood basophils and human asthma.

J. Virchow, C. Hack, C. Dahinden, 2006, Blood.

C-reactive protein levels and coronary artery disease incidence and mortality in apparently healthy men and women: the EPIC-Norfolk prospective population study 1993-2003.

R. Peters, N. Day, M. Sandhu, 2006, Atherosclerosis.

Inhibition of Plasmin Activity by Tranexamic Acid Does Not Influence Inflammatory Pathways During Human Endotoxemia

T. van der Poll, C. Hack, A. D. de Vos, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Immunisation of guinea-pigs with circulating immune complexes from patients with rheumatoid arthritis.

R. Aalberse, C. Hack, H. Lim, 1984, Annals of the rheumatic diseases.

IL4-10 synerkine to induce direct and indirect structural cartilage repair in osteoarthritis

S. Mastbergen, C. Hack, F. Lafeber, 2015 .

A Promoter Polymorphism in the CD59 Complement Regulatory Protein Gene in Donor Lungs Correlates With a Higher Risk for Chronic Rejection After Lung Transplantation

H. Otten, K. Budding, J. Broen, 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.