J. Searles

发表

PERFUSION CULTURE OF SUSPENDED CHO CELLS EMPLOYING INCLINED SEDIMENTATION

D. Kompala, P. Todd, J. Searles, 1994 .

Spray Drying of Biopharmaceuticals and Vaccines

J. Searles, G. Mohan, 2010 .

Stress Factors in Protein Drug Product Manufacturing and Their Impact on Product Quality.

W. Jiskoot, L. Narhi, Danny K. Chou, 2021, Journal of pharmaceutical sciences.

Recommended Best Practices for Process Monitoring Instrumentation in Pharmaceutical Freeze Drying—2017

Alina A. Alexeenko, W. Kessler, M. Pikal, 2017, AAPS PharmSciTech.

Dry powder measles vaccine: particle deposition, virus replication, and immune response in cotton rats following inhalation.

K. Kisich, S. Winston, R. Sievers, 2011, Vaccine.

Annealing to optimize the primary drying rate, reduce freezing-induced drying rate heterogeneity, and determine T(g)' in pharmaceutical lyophilization.

J. Carpenter, T. Randolph, J A Searles, 2001, Journal of pharmaceutical sciences.

The ice nucleation temperature determines the primary drying rate of lyophilization for samples frozen on a temperature-controlled shelf.

J. Carpenter, T. Randolph, J A Searles, 2001, Journal of pharmaceutical sciences.

Freezing and Annealing Phenomena in Lyophilization

J. Searles, 2016 .

Computational and experimental investigation of flow and particle settling in a roller bottle bioreactor.

F. Muzzio, D. R. Unger, J. Searles, 1999, Biotechnology and bioengineering.

Accelerated storage for shelf-life prediction of lyophiles: temperature dependence of degradation of amorphous small molecular weight drugs and proteins.

C. Roberts, S. Ohtake, Ehab Moussa, 2023, Journal of pharmaceutical sciences.

Near-critical fluid micronization of stabilized vaccines, antibiotics and anti-virals

Mark Hernandez, K. Kisich, C. Braun, 2007 .

Viable Cell Recycle with an Inclined Settler in the Perfusion Culture of Suspended Recombinant Chinese Hamster Ovary Cells

D. Kompala, P. Todd, J A Searles, 1994, Biotechnology progress.

Challenges and Considerations for New Technology Implementation and Synergy with Development of Process Analytical Technologies ( PAT )

Howard Stamato, James A. Searles, H. Stamato, 2020 .

Vial breakage in lyophilization- case studies from commercial manufacturing and laboratory studies.

J. Searles, Dina V. Lyne, E. Owen, 2022, Journal of pharmaceutical sciences.

Elements of Quality by Design in Development and Scale-Up of Freeze-Dried Parenterals

Steven L. Nail, James A. Searles, S. Nail, 2008 .

Alternatives to Vial Lyophilization

Jim Searles, Mathew Cherian, J. Searles, 2015 .