B. Riederer

发表

Independence of apical Cl-/HCO3- exchange and anion conductance in duodenal HCO3- secretion.

H. Rossmann, M. Gregor, U. Seidler, 2003, American journal of physiology. Gastrointestinal and liver physiology.

Slc26a3 deletion alters pH‐microclimate, mucin biosynthesis, microbiome composition and increases the TNFα expression in murine colon

S. Suerbaum, W. Xia, U. Seidler, 2020, Acta physiologica.

Preserved Na+/H+ exchanger isoform 3 expression and localization, but decreased NHE3 function indicate regulatory sodium transport defect in ulcerative colitis†

M. Manns, J. Wedemeyer, P. Hegyi, 2010, Inflammatory bowel diseases.

Recent advances in the molecular and functional characterization of acid/base and electrolyte transporters in the basolateral membranes of gastric and duodenal epithelial cells

P. Song, O. Bachmann, U. Seidler, 2011, Acta physiologica.

X-ray microanalysis of airway surface liquid in the mouse.

W. Colledge, M. Phillipson, U. Seidler, 2005, American journal of physiology. Lung cellular and molecular physiology.

mouse microanalysis of airway surface liquid in the

W. Colledge, M. Phillipson, U. Seidler, 2005 .

CFTR and its key role in in vivo resting and luminal acid‐induced duodenal HCO3− secretion

M. Manns, U. Seidler, M. Sjöblom, 2008, Acta physiologica.

Deletion of the chloride transporter Slc26a9 causes loss of tubulovesicles in parietal cells and impairs acid secretion in the stomach

S. Alper, P. Song, G. Shull, 2008, Proceedings of the National Academy of Sciences.

Sodium and chloride absorptive defects in the small intestine in Slc26a6 null mice

M. Manns, M. Wiemann, U. Seidler, 2007, Pflügers Archiv - European Journal of Physiology.

Renal and intestinal transport defects in Slc26a6-null mice.

J. Lorenz, P. Aronson, Tong Wang, 2005, American journal of physiology. Cell physiology.

Kidney and Intestine Transport Defects in Slc 26 a 6 Null Mice

J. Lorenz, P. Aronson, Tong Wang, 2004 .

Identification of an apical Cl-/HCO3- exchanger in gastric surface mucous and duodenal villus cells.

G. Shull, P. Dudeja, K. Ramaswamy, 2003, American journal of physiology. Gastrointestinal and liver physiology.

Hydrokinetic pancreatic function and insulin secretion are moduled by Cl− uniporter Slc26a9 in mice

K. Herzig, U. Seidler, G. Raza, 2021, Acta physiologica.

Lactate flux in astrocytes is enhanced by a non‐catalytic action of carbonic anhydrase II

R. McKenna, G. Wennemuth, J. Deitmer, 2012, The Journal of physiology.

The Scavenger Receptor Class B, Type I Is a Primary Determinant of Paraoxonase-1 Association With High-Density Lipoproteins

Ashutosh Kumar Singh, T. V. van Berkel, U. Seidler, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Slc26a3 deficiency is associated with loss of colonic HCO3− secretion, absence of a firm mucus layer and barrier impairment in mice

W. Xia, M. Montrose, M. Johansson, 2014, Acta physiologica.

Calcium‐sensing receptor regulates intestinal dipeptide absorption via Ca2+ signaling and IKCa activation

O. Griesbeck, H. Daniel, A. Zeug, 2020, Physiological reports.

cAMP-dependent and cholinergic regulation of the electrogenic intestinal/pancreatic Na+/HCO3- cotransporter pNBC1 in human embryonic kidney (HEK293) cells

M. Manns, O. Bachmann, U. Seidler, 2008, BMC Cell Biology.

The Role of Pancreatic Ductal Secretion in Protection Against Acute Pancreatitis in Mice*

P. Hegyi, Z. Rakonczay, T. Wittmann, 2014, Critical care medicine.

Kir4.1 Channel Expression Is Essential for Parietal Cell Control of Acid Secretion*

M. Manns, P. Song, U. Seidler, 2011, The Journal of Biological Chemistry.

Loss of downregulated in adenoma (DRA) impairs mucosal HCO3− secretion in murine ileocolonic inflammation

G. Kollias, Lifei Zheng, P. Dudeja, 2012, Inflammatory bowel diseases.

Differential Association of the Na+/H+ Exchanger Regulatory Factor (NHERF) Family of Adaptor Proteins with the Raft- and the Non-Raft Brush Border Membrane Fractions of NHE3

M. Donowitz, C. Yun, W. Xia, 2013, Cellular Physiology and Biochemistry.

The switch of intestinal Slc26 exchangers from anion absorptive to HCOFormula secretory mode is dependent on CFTR anion channel function.

O. Nylander, U. Seidler, M. Soleimani, 2010, American journal of physiology. Cell physiology.

Parietal cell-Specific SLC26A9 Deletion induces spontaneous Gastric Carcinogenesis in Mice

U. Seidler, Taolang Li, Zhiyuan Ma, 2020, bioRxiv.

Loss of luminal carbonic anhydrase XIV results in decreased biliary bicarbonate output, liver fibrosis, and cholangiocyte proliferation in mice

G. Gros, U. Seidler, B. Riederer, 2022, Pflügers Archiv - European Journal of Physiology.

Loss of Slc26a9 anion transporter alters intestinal electrolyte and HCO3- transport and reduces survival in CFTR-deficient mice

U. Seidler, H. Lenzen, Taolang Li, 2014, Pflügers Archiv - European Journal of Physiology.

Absence of Slc26a9 results in altered tracheobronchial anion transport and high mortality in neonate mice (1181.7)

P. Anagnostopoulou, U. Seidler, M. Mall, 2014 .

Knockout mouse models for intestinal electrolyte transporters and regulatory PDZ adaptors: new insights into cystic fibrosis, secretory diarrhoea and fructose‐induced hypertension

O. Bachmann, U. Seidler, Anurag Kumar Singh, 2009, Experimental physiology.

The Role of the NHERF Family of PDZ Scaffolding Proteins in the Regulation of Salt and Water Transport

Ashutosh Kumar Singh, U. Seidler, B. Riederer, 2009, Annals of the New York Academy of Sciences.

Defective jejunal and colonic salt absorption and alteredNa+/H+ exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice

M. Donowitz, A. Hubbard, E. Weinman, 2009, Pflügers Archiv - European Journal of Physiology.

Genetic ablation of carbonic anhydrase IX disrupts gastric barrier function via claudin‐18 downregulation and acid backflux

K. Herzig, G. Gros, U. Seidler, 2017, Acta physiologica.

KCNQ1 is the luminal K+ recycling channel during stimulation of gastric acid secretion

P. Song, U. Seidler, Zhe Feng, 2009, The Journal of physiology.

Localization, trafficking, and significance for acid secretion of parietal cell Kir4.1 and KCNQ1 K+ channels.

M. Manns, M. Kaufhold, P. Song, 2008, Gastroenterology.

Secretagogue stimulation enhances NBCe1 (electrogenic Na(+)/HCO(3)(-) cotransporter) surface expression in murine colonic crypts.

M. Manns, W. Boron, G. Shull, 2009, American journal of physiology. Gastrointestinal and liver physiology.

Online Laboratory Investigations

P. Hegyi, Z. Rakonczay, T. Wittmann, 2014 .

IL-1β-Induced Downregulation of the Multifunctional PDZ Adaptor PDZK1 Is Attenuated by ERK Inhibition, RXRα, or PPARα Stimulation in Enterocytes

M. Menon, U. Seidler, K. Tachibana, 2017, Front. Physiol..

Short-Term Regulation of Murine Colonic NBCe1-B (Electrogenic Na+/HCO3 − Cotransporter) Membrane Expression and Activity by Protein Kinase C

M. Manns, O. Bachmann, U. Seidler, 2014, PloS one.

Duodenal acidity “sensing” but not epithelial HCO3− supply is critically dependent on carbonic anhydrase II expression

G. Gros, U. Seidler, M. Sjöblom, 2009, Proceedings of the National Academy of Sciences.

Slc26a3 deficiency is associated with epididymis dysplasia and impaired sperm fertilization potential in the mouse

F. Saez, A. Touré, E. El Khouri, 2018, Molecular reproduction and development.

Slc26a3/Dra and Slc26a6 in Murine Ameloblasts

D. Micha, B. Zandieh-Doulabi, A. Bronckers, 2015, Journal of dental research.

The electroneutral Na+HCO3− cotransporter NBCn1 plays an essential role in duodenal acid/base balance and colonic mucus layer build‐up in anaestetised mice

Ashutosh Kumar Singh, C. Aalkjaer, W. Xia, 2013 .

The electroneutral Na+:HCO3− cotransporter NBCn1 is a major pHi regulator in murine duodenum

Ashutosh Kumar Singh, C. Aalkjaer, G. Shull, 2012, The Journal of physiology.

Defective small intestinal anion secretion, dipeptide absorption, and intestinal failure in suckling NBCe1-deficient mice

G. Shull, U. Seidler, Taolang Li, 2016, Pflügers Archiv - European Journal of Physiology.

Molecular transport machinery involved in orchestrating luminal acid‐induced duodenal bicarbonate secretion in vivo

Ashutosh Kumar Singh, B. K. Thakur, U. Seidler, 2013, The Journal of physiology.

New therapeutic targets in ulcerative colitis: The importance of ion transporters in the human colon

P. Hegyi, Z. Rakonczay, K. Farkas, 2011, Inflammatory bowel diseases.

Involvement of the anion exchanger SLC26A6 in prostaglandin E2- but not forskolin-stimulated duodenal HCO3- secretion.

W. Colledge, U. Seidler, M. Soleimani, 2006, Gastroenterology.

Telomere shortening is associated with reduced duodenal HCOFormula secretory but normal gastric acid secretory capacity in aging mice.

M. Manns, K. Rudolph, Z. Ju, 2012, American journal of physiology. Gastrointestinal and liver physiology.

mode is dependent on CFTR anion channel function 2

O. Nylander, U. Seidler, M. Soleimani, 2010 .

Down regulation of small intestinal ion transport in PDZK1- (CAP70/NHERF3) deficient mice

M. Manns, C. Yun, U. Seidler, 2007, Pflügers Archiv - European Journal of Physiology.

Oral Sessions

Capasso, A. Cantone, F. Artunc, 2014 .

Loss of PDZ‐adaptor protein NHERF2 affects membrane localization and cGMP‐ and [Ca2+]‐ but not cAMP‐dependent regulation of Na+/H+ exchanger 3 in murine intestine

M. Donowitz, C. Yun, Gang Chen, 2010, The Journal of physiology.

Deletion of the Chloride Transporter Slc26a7 Causes Distal Renal Tubular Acidosis and Impairs Gastric Acid Secretion*

S. Alper, P. Song, Marian L Miller, 2009, The Journal of Biological Chemistry.

Hypoxia inducible factor-1 (HIF-1)-mediated repression of cystic fibrosis transmembrane conductance regulator (CFTR) in the intestinal epithelium.

S. Colgan, H. Eltzschig, U. Seidler, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Molecular Mechanisms of Disturbed Electrolyte Transport in Intestinal Inflammation

A. Bleich, U. Seidler, H. Lenzen, 2006, Annals of the New York Academy of Sciences.

NHE3 inhibition by cAMP and Ca2+ is abolished in PDZ‐domain protein PDZK1‐deficient murine enterocytes

M. Manns, M. Wiemann, O. Bachmann, 2007, The Journal of physiology.

Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.

M. Donowitz, C. Yun, U. Lehmann, 2009, The Journal of clinical investigation.

Loss of Slc26a9 anion transporter alters intestinal electrolyte and HCO3- transport and reduces survival in CFTR-deficient mice

U. Seidler, H. Lenzen, Taolang Li, 2014, Pflügers Archiv - European Journal of Physiology.

An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells

P. Avan, C. Petit, A. El-Amraoui, 2014, Proceedings of the National Academy of Sciences.

SLC26A9 deficiency causes gastric intraepithelial neoplasia in mice and aggressive gastric cancer in humans

U. Seidler, Taolang Li, Zhiyuan Ma, 2022, Cellular Oncology.

Rescue of epithelial HCO3− secretion in murine intestine by apical membrane expression of the cystic fibrosis transmembrane conductance regulator mutant F508del

Min Goo Lee, B. Scholte, U. Seidler, 2012, The Journal of physiology.

The Na+/H+ exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE3 upregulation.

M. Manns, H. Rossmann, M. Gregor, 2004, American journal of physiology. Gastrointestinal and liver physiology.

Evidence for a causal link between adaptor protein PDZK1 downregulation and Na+/H+ exchanger NHE3 dysfunction in human and murine colitis

C. Yun, A. Bleich, D. Bruder, 2014, Pflügers Archiv - European Journal of Physiology.

Essential role of the electroneutral Na+–HCO3− cotransporter NBCn1 in murine duodenal acid–base balance and colonic mucus layer build‐up in vivo

Ashutosh Kumar Singh, P. Song, C. Aalkjaer, 2013, The Journal of physiology.

Na+/H+ exchanger NHE1 and NHE2 have opposite effects on migration velocity in rat gastric surface cells

R. Stripecke, F. Busch, M. Menon, 2017, Journal of cellular physiology.

Erratum to: The distinct roles of anion transporters Slc26a3 (DRA) and Slc26a6 (PAT-1) in fluid and electrolyte absorption in the murine small intestine

Ashutosh Kumar Singh, P. Song, W. Xia, 2014, Pflügers Archiv - European Journal of Physiology.

The Na / H exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE 3 upregulation

M. Manns, H. Rossmann, M. Gregor, 2004 .

Adrenaline‐induced colonic K+ secretion is mediated by KCa1.1 (BK) channels

P. Ruth, M. Sausbier, U. Seidler, 2010, The Journal of physiology.

Deciphering ion transporters, kinases and PDZ-adaptor molecules that mediate guanylate cyclase C agonist-dependent intestinal fluid loss in vivo.

U. Seidler, B. Riederer, Q. Tan, 2020, Biochemical pharmacology.

Upregulation of antimicrobial peptide expression in slc26a3-/- mice with colonic dysbiosis and barrier defect

A. Bleich, T. Strowig, U. Seidler, 2022, Gut microbes.

Pseudomonas aeruginosa reduces the expression of CFTR via post-translational modification of NHERF1

Ashutosh Kumar Singh, A. Bragonzi, A. Tamanini, 2014, Pflügers Archiv - European Journal of Physiology.

Pseudomonas aeruginosa reduces the expression of CFTR via post-translational modification of NHERF1

Ashutosh Kumar Singh, A. Bragonzi, A. Tamanini, 2014, Pflügers Archiv - European Journal of Physiology.

D-Lysergyl Peptide Synthetase from the Ergot Fungus Claviceps purpurea *

U. Keller, M. Han, B. Riederer, 1996, The Journal of Biological Chemistry.

SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation.

Thomas Thum, Michael Kabesch, M. Kabesch, 2012, The Journal of clinical investigation.

The distinct roles of anion transporters Slc26a3 (DRA) and Slc26a6 (PAT-1) in fluid and electrolyte absorption in the murine small intestine

P. Song, W. Xia, U. Seidler, 2013, Pflügers Archiv - European Journal of Physiology.

Defective small intestinal anion secretion, dipeptide absorption, and intestinal failure in suckling NBCe1-deficient mice

G. Shull, U. Seidler, Taolang Li, 2016, Pflügers Archiv - European Journal of Physiology.

Na⁺/H⁺ exchanger regulatory factor 3 is critical for multidrug resistance protein 4-mediated drug efflux in the kidney.

Min Goo Lee, H. Lee, S. Cole, 2014, Journal of the American Society of Nephrology : JASN.

Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.

M. Donowitz, C. Yun, U. Lehmann, 2009, The Journal of clinical investigation.

The switch of intestinal Slc26 exchangers from anion absorptive to HCO 3 (cid:1) secretory mode is dependent on CFTR anion channel function

O. Nylander, U. Seidler, M. Soleimani, 2010 .

Lactate flux in astrocytes is enhanced by a non‐catalytic action of carbonic anhydrase II

R. McKenna, G. Wennemuth, J. Deitmer, 2012, The Journal of physiology.

Hypoxia inducible factor‐1 (HIF‐l)‐mediated repression of cystic fibrosis transmembrane conductance regulator (CFTR) in the intestinal epithelium

S. Colgan, H. Eltzschig, U. Seidler, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation.

M. Kabesch, T. Thum, P. Anagnostopoulou, 2012, The Journal of clinical investigation.

Sa1946 Role of the Electrogenic Na+HCO3- Cotransporter NBCe1 in PHI Regulation and Anion Secretion in Murine Intestine

G. Shull, U. Seidler, Xuemei Liu, 2013 .

322 Colonic SLC26A3 Establishes Alkaline Mucus Layer and Its Loss Results in Barrier Impairment and Mucosal Inflammation in Mice

W. Xia, M. Montrose, M. Johansson, 2012 .

cGMP‐dependent kinase 2, Na+/H+ exchanger NHE3, and PDZ‐adaptor NHERF2 co‐assemble in apical membrane microdomains

B. Riederer, Min Luo, K. Nikolovska, 2024, Acta physiologica.