Matthew C. O’Reilly

发表

Discovery-Based Bromination of Alcohols: An Organic Chemistry Experiment Supporting Spectroscopic Analysis and Mechanistic Reasoning

Matthew C. O’Reilly, Stacey A. Stoffregen, Karl P. Peterson, 2021, Journal of Chemical Education.

Design, synthesis, and biochemical characterization of non-native antagonists of the Pseudomonas aeruginosa quorum sensing receptor LasR with nanomolar IC50 values.

H. Blackwell, Matthew C. O’Reilly, K. Nyffeler, 2020, ACS infectious diseases.

Design, synthesis, and biochemical characterization of non-native antagonists of the Pseudomonas aeruginosa quorum sensing receptor LasR with nanomolar IC 50 values

H. Blackwell, Matthew C. O’Reilly, K. Nyffeler, 2020 .

Structural and Biochemical Studies of Non-native Agonists of the LasR Quorum-Sensing Receptor Reveal an L3 Loop "Out" Conformation for LasR.

S. Nair, H. Blackwell, S. Dong, 2018, Cell chemical biology.

Synthesis and Characterization of Functionalized Amino Dihydropyrimidines Toward the Analysis of their Antibacterial Structure–Activity Relationships and Mechanism of Action

C. Bourne, Matthew C. O’Reilly, Zachary W. Boyer, 2022, ACS omega.

A general, enantioselective synthesis of N-alkyl terminal aziridines and C2-functionalized azetidines via organocatalysis

C. Lindsley, G. Sulikowski, Timothy J Senter, 2015, Tetrahedron letters.

Development of dual PLD1/2 and PLD2 selective inhibitors from a common 1,3,8-Triazaspiro[4.5]decane Core: discovery of Ml298 and Ml299 that decrease invasive migration in U87-MG glioblastoma cells.

Craig W Lindsley, Paul G Thomas, Sarah A. Scott, 2013, Journal of medicinal chemistry.

Diastereoselective synthesis of cyclic tetrapeptide pseudoxylallemycin A illuminates the impact of base during macrolactamization.

R. C. Roberts, Matthew C. O’Reilly, Jieyu Zhang, 2023, Organic & biomolecular chemistry.

A general, enantioselective synthesis of protected morpholines and piperazines.

C. Lindsley, Matthew C. O’Reilly, 2012, Organic letters.

Enantioselective synthesis of C2-functionalized, N-protected morpholines and orthogonally N,N'-protected piperazines via organocatalysis.

C. Lindsley, Matthew C. O’Reilly, 2012, Tetrahedron letters.

A general, enantioselective synthesis of β- and γ-fluoroamines.

C. Lindsley, Matthew C. O’Reilly, 2013, Tetrahedron letters.

Discovery of Desketoraloxifene Analogues as Inhibitors of Mammalian, Pseudomonas aeruginosa, and NAPE Phospholipase D Enzymes

Sarah A. Scott, Kyle A. Brown, C. Lindsley, 2014, ACS chemical biology.

Further evaluation of novel structural modifications to scaffolds that engender PLD isoform selective inhibition.

Sarah A. Scott, C. Lindsley, H. Brown, 2014, Bioorganic & medicinal chemistry letters.

Discovery of a Highly Selective PLD2 Inhibitor (ML395): A New Probe with Improved Physiochemical Properties and Broad‐Spectrum Antiviral Activity against Influenza Strains

Sarah A. Scott, P. Thomas, C. Lindsley, 2014, ChemMedChem.

Regulation of Phospholipase D Activity and Phosphatidic Acid Production after Purinergic (P2Y6) Receptor Stimulation*

Sarah A. Scott, C. Lindsley, H. Brown, 2013, The Journal of Biological Chemistry.

Structure-Based Design and Biological Evaluation of Triphenyl Scaffold-Based Hybrid Compounds as Hydrolytically Stable Modulators of a LuxR-Type Quorum Sensing Receptor

H. Blackwell, Matthew C. O’Reilly, 2015, ACS infectious diseases.

What’s in a Tablet? Extraction and Spectroscopic Identification of Pharmaceutical Unknowns

Christopher M. Russo, Matthew C. O’Reilly, Hannah Kessler, 2022, Journal of Chemical Education.