M. Mense

发表

A Novel Approach to Recovery of Function of Mutant Proteins by Slowing Down Translation*

K. Rock, M. Sherman, H. Bihler, 2012, The Journal of Biological Chemistry.

Comparison of Ion Adsorption to Phophatidylcholine/Phosphatidylserine and Sarcoplasmic Reticulum Membranes

M. Mense, 2000 .

Discovery of Clinically Approved Agents That Promote Suppression of Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations.

D. Bedwell, K. Keeling, S. Rowe, 2016, American journal of respiratory and critical care medicine.

Partial rescue of F508del‐cystic fibrosis transmembrane conductance regulator channel gating with modest improvement of protein processing, but not stability, by a dual‐acting small molecule

Nikhil T. Awatade, M. Amaral, C. Farinha, 2018, British journal of pharmacology.

CFTR mRNAs with nonsense codons are degraded by the SMG6-mediated endonucleolytic pathway

Shuling Guo, A. Revenko, Lulu Huang, 2021 .

Nonsense Mediated RNA Decay Pathway Inhibition Restores Expression and Function of W1282X CFTR.

Shuling Guo, B. Monia, H. Bihler, 2019, American journal of respiratory cell and molecular biology.

E5 oncoprotein transmembrane mutants dissociate fibroblast transforming activity from 16-kilodalton protein binding and platelet-derived growth factor receptor binding and phosphorylation

R. Schlegel, J. Sparkowski, J. Anders, 1996, Journal of virology.

Electrokinetic Properties of the Sarcoplasmic Reticulum Membrane Obtained from Reconstitution Studies

P. Smejtek, M. Mense, S. Wang, 1999, The Journal of Membrane Biology.

Ultrastructure of Contact-Chemoreceptor Sensilla Found Among the Genae of Female

W. Bonn, D. Lindsay, N. Thomas, 2005 .

Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells.

Hongmei Mou, Colleen Keyes, Martin Mense, 2016, Cell stem cell.

Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition

J. Ernst, K. Plath, C. Yao, 2021, Nature Medicine.

Effects of Free Radicals on Partial Reactions of the Na,K-ATPase

H. Apell, G. Stark, M. Mense, 1997, The Journal of Membrane Biology.

A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion

R. Green, E. Mendenhall, R. Bostwick, 2021, Nature Communications.

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

Aviv Regev, Hui Min Leung, Guillermo J. Tearney, 2018, Nature.

Isogenic cell models of cystic fibrosis-causing variants in natively expressing pulmonary epithelial cells.

A. Sivachenko, P. Thomas, H. Bihler, 2019, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

CFTR modulator theratyping: Current status, gaps and future directions.

J. Wallenburg, J. Clancy, J. Nick, 2019, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

Daniel T. Montoro, Adam L. Haber, A. Regev, 2018, Nature.

Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope

David R. Liu, Gregory A. Newby, Anton P. McCaffrey, 2020, Nature Communications.

A molecular atlas of proximal airway identifies subsets of known airway cell types revealing details of the unique molecular pathogenesis of Cystic Fibrosis

K. Plath, C. Yao, B. Stripp, 2020, bioRxiv.

Extracellular domains, transmembrane segments, and intracellular domains interact to determine the cation selectivity of Na,K- and gastric H,K-ATPase.

M. Caplan, V. Rajendran, R. Blostein, 2002, Biochemistry.

Residues of the Fourth Transmembrane Segments of the Na,K-ATPase and the Gastric H,K-ATPase Contribute to Cation Selectivity*

M. Caplan, R. Blostein, L. Dunbar, 2000, The Journal of Biological Chemistry.

High-Throughput Screening for Readthrough Modulators of CFTR PTC Mutations

H. Bihler, J. Mahiou, M. Mense, 2017, SLAS technology.

CFTR mRNAs with nonsense codons are degraded by the SMG6-mediated endonucleolytic decay pathway

Shuling Guo, B. Monia, A. Revenko, 2022, Nature Communications.

Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope

David R. Liu, Gregory A. Newby, Daniel G. Anderson, 2020, Nature Communications.

Cation Selectivity of Gastric H,K-ATPase and Na,K-ATPase Chimeras*

M. Caplan, A. Wilczyńska, R. Blostein, 1999, The Journal of Biological Chemistry.

Exploring the basic mechanisms in Cystic Fibrosis: Promoting data presentation and discussion at the 16th ECFS Basic Science Conference.

C. Farinha, I. Callebaut, M. Mense, 2020, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Conformational Changes Relevant to Channel Activity and Folding within the first Nucleotide Binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator*

Hanoch Senderowitz, Julie D. Forman-Kay, Efrat Noy, 2012, The Journal of Biological Chemistry.

Control of the CFTR channel's gates.

A. Nairn, D. Gadsby, C. Basso, 2005, Biochemical Society transactions.

Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening

Efrat Ben-Zeev, Martin Mense, Ori Kalid, 2010, J. Comput. Aided Mol. Des..

In vivo phosphorylation of CFTR promotes formation of a nucleotide‐binding domain heterodimer

Angus C Nairn, Paola Vergani, Martin Mense, 2006, The EMBO journal.

In Vitro Modulator Responsiveness of 655 CFTR Variants Found in People With CF

A. Sivachenko, G. Cutting, L. Millen, 2023, bioRxiv.

635 Genome-wide screen to uncover genes promoting premature termination codon readthrough

N. Allaire, J. Mahiou, M. Mense, 2022, Journal of Cystic Fibrosis.

Anticodon Engineered Transfer RNAs (ACE-tRNAs) are a Platform Technology for Suppressing Nonsense Mutations

M. Mense, S. Spelier, I. S. van der Windt, 2024, bioRxiv.

Conformational Changes Relevant to Channel Activity and Folding within the first Nucleotide Binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator*

H. Senderowitz, R. Vernon, Inbal Sela-Culang, 2012, The Journal of Biological Chemistry.

In vitro modulator responsiveness of 655 CFTR variants found in people with cystic fibrosis.

A. Sivachenko, L. Millen, K. Raraigh, 2024, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

CFTR and Cystic Fibrosis

P. Thomas, M. Mense, 2015 .

Partial rescue of F508del-cystic fibrosis transmembrane conductance regulator channel gating with modest improvement of protein processing, but not stability, by a dual-acting small

Nikhil T. Awatade, C. Farinha, H. Bihler, 2017 .

Upregulation of a nonsense mediated decay (NMD) insensitive CFTR mRNA isoform has therapeutic potential for the treatment of 3’ CFTR PTC variants

H. Bihler, M. Mense, Yi Cheng, 2024, bioRxiv.