Shi-Liang Huang

发表

Synthesis and evaluation of new BODIPY-benzofuroquinoline conjugates for sensitive and selective DNA detection

Ding Li, Shuo-Bin Chen, Zhishu Huang, 2014 .

Synthesis and Biological Evaluation of Novel Bouchardatine Derivatives as Potential Adipogenesis/Lipogenesis Inhibitors for Antiobesity Treatment.

Ji-Ming Ye, Ding Li, Yong Rao, 2015, Journal of medicinal chemistry.

Synthesis and Mechanism Studies of 1,3-Benzoazolyl Substituted Pyrrolo[2,3-b]pyrazine Derivatives as Nonintercalative Topoisomerase II Catalytic Inhibitors.

Ding Li, Shuo-Bin Chen, Zhishu Huang, 2016, Journal of medicinal chemistry.

Synthesis and antimultidrug resistance evaluation of icariin and its derivatives.

Min Huang, Zhishu Huang, Tian-Miao Ou, 2009, Bioorganic & medicinal chemistry letters.

Syntheses and characterization of novel oxoisoaporphine derivatives as dual inhibitors for cholinesterases and amyloid beta aggregation.

Ding Li, Zhishu Huang, Tian-Miao Ou, 2011, European journal of medicinal chemistry.

Discovery of a promising agent IQZ23 for the treatment of obesity and related metabolic disorders.

Ji-Ming Ye, Yong Rao, Chan Li, 2020, European journal of medicinal chemistry.

Discovery of natural alkaloid bouchardatine as a novel inhibitor of adipogenesis/lipogenesis in 3T3-L1 adipocytes.

Yong Rao, Zhishu Huang, Tian-Miao Ou, 2015, Bioorganic & medicinal chemistry.

Synthesis and evaluation of 1,2,3,4-tetrahydro-1-acridone analogues as potential dual inhibitors for amyloid-beta and tau aggregation.

Zhishu Huang, Shi-Liang Huang, Ning Wang, 2018, Bioorganic & medicinal chemistry.

Discovery of a Novel G-Quadruplex and Histone Deacetylase (HDAC) Dual-Targeting Agent for the Treatment of Triple-Negative Breast Cancer.

Yong Rao, Shuo-Bin Chen, Zhishu Huang, 2022, Journal of medicinal chemistry.

Design, Synthesis, and Evaluation of New Sugar-Substituted Imidazole Derivatives as Selective c-MYC Transcription Repressors Targeting the Promoter G-Quadruplex.

Ding Li, Shuo-Bin Chen, Zhishu Huang, 2022, Journal of medicinal chemistry.

Construction of the oxaphenalene skeletons of mansonone F derivatives through C–H bond functionalization and their evaluation for anti-proliferative activities

Zhishu Huang, L. Gu, Shi-Liang Huang, 2017 .

Hybrids of Oxoisoaporphine‐Tacrine Congeners: Novel Acetylcholinesterase and Acetylcholinesterase‐Induced β‐Amyloid Aggregation Inhibitors.

Hong Liang, Zhenfeng Chen, Zhishu Huang, 2012 .

Design, synthesis and evaluation of isaindigotone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors.

Jin-Qiang Hou, Zhishu Huang, Jia-Heng Tan, 2008, Bioorganic & medicinal chemistry letters.

New quinazoline derivatives for telomeric G-quadruplex DNA: effects of an added phenyl group on quadruplex binding ability.

Ding Li, Zhishu Huang, Tian-Miao Ou, 2013, European journal of medicinal chemistry.

2-(2-indolyl-)-4(3H)-quinazolines derivates as new inhibitors of AChE: design, synthesis, biological evaluation and molecular modelling

Bin Wang, Ding Li, Jin-Qiang Hou, 2013, Journal of enzyme inhibition and medicinal chemistry.

Design, synthesis and evaluation of 2-arylethenyl-N-methylquinolinium derivatives as effective multifunctional agents for Alzheimer's disease treatment.

Ding Li, Zhishu Huang, Qian-Liang Guo, 2017, European journal of medicinal chemistry.

Hybrids of oxoisoaporphine-tacrine congeners: novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors.

Hong Liang, Zhenfeng Chen, Zhishu Huang, 2011, European journal of medicinal chemistry.

Derivatives of oxoisoaporphine alkaloids: a novel class of selective acetylcholinesterase inhibitors.

A. Chan, Zhishu Huang, L. Gu, 2007, Bioorganic & medicinal chemistry letters.

Discovery of Quinacrine as a Potent Topo II and Hsp90 Dual-Target Inhibitor, Repurposing for Cancer Therapy

Yong Rao, Zhishu Huang, Shi-Liang Huang, 2022, Molecules.

Design, synthesis and biological evaluation of novel mansonone E derivatives prepared via CuAAC click chemistry as topoisomerase II inhibitors.

Ding Li, Zhishu Huang, Tian-Miao Ou, 2013, European journal of medicinal chemistry.

Synthesis of novel dihydrofuro[b]-pyridinone derivatives: oxidation coupling of 3-hydroxy-4(1H)-pyridinone with β-dicarbonyl compounds

A. Chan, Zhishu Huang, L. Gu, 2005 .

Synthesis of Phenoxazinone Derivatives and Antiproliferative Activities on Wild-type and Drug-resistant Tumor Cells

Zhishu Huang, Li-wu Fu, L. Gu, 2006 .

Synthesis and evaluation of graveoline and graveolinine derivatives with potent anti-angiogenesis activities.

Zhishu Huang, Tian-Miao Ou, Jia-Heng Tan, 2010, European journal of medicinal chemistry.

Synthesis of Benzofused N-Heterocycles via Rh(III)-Catalyzed Direct Benzannulation with 1,3-Dienes

Xianxing Jiang, Honggen Wang, Shi-Liang Huang, 2018, ACS Catalysis.

Design, synthesis, and biological evaluation of 2-arylethenylquinoline derivatives as multifunctional agents for the treatment of Alzheimer's disease.

Ding Li, Shuo-Bin Chen, Zhishu Huang, 2015, European journal of medicinal chemistry.

Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA.

Hai-bin Luo, Jin-Qiang Hou, Kwok‐yin Wong, 2009, Journal of medicinal chemistry.

Oxoisoaporphine alkaloid derivatives: synthesis, DNA binding affinity and cytotoxicity.

A. Chan, Zhishu Huang, Xiao-dong Wang, 2008, European journal of medicinal chemistry.

Design, Synthesis and Evaluation of New Quinazolinone Derivatives that Inhibit Bloom's Syndrome Protein (BLM) Helicase, Trigger DNA damage at the Telomere Region and Synergize with PARP Inhibitors.

Ding Li, Yong Rao, Yao-Hao Xu, 2020, Journal of medicinal chemistry.

Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors.

Zhishu Huang, C. Zhang, Shi-Liang Huang, 2019, Bioorganic chemistry.

Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.

Ding Li, Shuo-Bin Chen, Zhishu Huang, 2013, Organic & biomolecular chemistry.

Synthesis of allenyl-B(MIDA) via hydrazination/fragmentation reaction of B(MIDA)-propargylic alcohol

Yuan Liu, Qingjiang Li, Honggen Wang, 2022, Chinese Chemical Letters.

Pharmacophore-based discovery of triaryl-substituted imidazole as new telomeric G-quadruplex ligand.

Ding Li, Shuo-Bin Chen, Jia-Heng Tan, 2011, Bioorganic & medicinal chemistry letters.

Design, synthesis and biological evaluation of novel 7-alkylamino substituted benzo[a]phenazin derivatives as dual topoisomerase I/II inhibitors.

Ding Li, Shuo-Bin Chen, Zhishu Huang, 2015, European journal of medicinal chemistry.

Multi-functional polyimides containing tetraphenyl fluorene moieties: fluorescence and resistive switching behaviors

Jia-rui Xu, Zhenguo Chi, Yi Zhang, 2017 .

Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as dual inhibitors for cholinesterases and amyloid beta aggregation.

Ding Li, Zhishu Huang, Tian-Miao Ou, 2011, Bioorganic & medicinal chemistry.

Synthesis and evaluation of curcumin analogues as potential thioredoxin reductase inhibitors.

Zhishu Huang, L. Gu, Xianzhang Bu, 2008, Bioorganic & medicinal chemistry.

Disubstituted 2-phenyl-benzopyranopyrimidine derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.

Ding Li, Jin-Qiang Hou, Zhishu Huang, 2011, Organic & biomolecular chemistry.

Biological Function and Medicinal Research Significance of G-Quadruplex Interactive Proteins.

Ding Li, Zhishu Huang, Tian-Miao Ou, 2015, Current topics in medicinal chemistry.

Discovery of Small Molecules for Up-Regulating the Translation of Antiamyloidogenic Secretase, a Disintegrin and Metalloproteinase 10 (ADAM10), by Binding to the G-Quadruplex-Forming Sequence in the 5' Untranslated Region (UTR) of Its mRNA.

Ding Li, Zhishu Huang, J. Dai, 2015, Journal of medicinal chemistry.

Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands.

Jin-Qiang Hou, Zhishu Huang, Tian-Miao Ou, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of mansonone F derivatives as topoisomerase inhibitors.

Ding Li, Shuo-Bin Chen, Zhishu Huang, 2011, European journal of medicinal chemistry.

Synthesis, biological evaluation and molecular modeling of oxoisoaporphine and oxoaporphine derivatives as new dual inhibitors of acetylcholinesterase/butyrylcholinesterase.

Wei Qiao, Zhishu Huang, Lin Ma, 2009, European journal of medicinal chemistry.

3D-QSAR studies of azaoxoisoaporphine, oxoaporphine, and oxoisoaporphine derivatives as anti-AChE and anti-AD agents by the CoMFA method.

Ding Li, Jin-Qiang Hou, Hai-Bin Luo, 2013, Journal of molecular graphics & modelling.

Synthesis and evaluation of 7,8-dehydrorutaecarpine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.

Ding Li, Shuo-Bin Chen, Zhishu Huang, 2013, European journal of medicinal chemistry.

Synthesis and characterization of 1H-phenanthro[9,10-d]imidazole derivatives as multifunctional agents for treatment of Alzheimer's disease.

Ding Li, Qiong Gu, Jun Xu, 2014, Biochimica et biophysica acta.

Discovery of Isaindigotone Derivatives as Novel Bloom's Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair.

Ding Li, Shuo-Bin Chen, Zhishu Huang, 2019, Journal of medicinal chemistry.

A novel HSF1 activator ameliorates non‐alcoholic steatohepatitis by stimulating mitochondrial adaptive oxidation

Shiying Guo, Yong Rao, Chan Li, 2021, British journal of pharmacology.

Synthesis and evaluation of novel rutaecarpine derivatives and related alkaloids derivatives as selective acetylcholinesterase inhibitors.

Bin Wang, Ding Li, Jin-Qiang Hou, 2010, European journal of medicinal chemistry.

2,3-Bis(2-chlorobenzyl)naphthalene-1,4-dione

Seik Weng Ng, Shi-Liang Huang, Zhi-Shu Huang, 2008, Acta crystallographica. Section E, Structure reports online.

Synthesis and Cytotoxicity of 9‐Substituted Benzo[de]chromene‐7,8‐dione and 5‐Benzyl‐9‐substituted Benzo[de]chromene‐7,8‐dione

A. Chan, Z. Liu, Zhishu Huang, 2006 .

Quinolino-benzo-[5, 6]-dihydroisoquindolium compounds derived from berberine: a new class of highly selective ligands for G-quadruplex DNA in c-myc oncogene.

Jin-Qiang Hou, Zhishu Huang, Tian-Miao Ou, 2011, European journal of medicinal chemistry.

Syntheses and evaluation of novel isoliquiritigenin derivatives as potential dual inhibitors for amyloid-beta aggregation and 5-lipoxygenase.

Ding Li, Jun Xu, Zhishu Huang, 2013, European journal of medicinal chemistry.

Inhibition of thioredoxin reductase by mansonone F analogues: Implications for anticancer activity.

Manmei Li, Zhishu Huang, L. Gu, 2009, Chemico-Biological Interactions.

Three-Component Catalytic Carboxygenation of Activated Alkenes Enabled by Bimetallic Rh(III)/Cu(II) Catalysis.

Qingjiang Li, Honggen Wang, Shi-Liang Huang, 2017, Organic letters.

Effective detection and separation method for G-quadruplex DNA based on its specific precipitation with Mg(2+).

Ding Li, Zhishu Huang, Tian-Miao Ou, 2010, Biomacromolecules.

Synthesis and evaluation of heterobivalent tacrine derivatives as potential multi-functional anti-Alzheimer agents.

Ding Li, Zhishu Huang, L. Gu, 2011, European journal of medicinal chemistry.

Syntheses And Evaluation Of Asymmetric Curcumin Analogues As Potential Multifunctional Agents For The Treatment Of Alzheimer's Disease.

Ding Li, Zhishu Huang, Tian-Miao Ou, 2015, Current Alzheimer research.

Disubstituted 2-phenyl-benzopyranopyrimidine derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.

Ding Li, Jin-Qiang Hou, Zhishu Huang, 2011, Organic & biomolecular chemistry.