A. Tan

发表

Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge

R. Abagyan, Hualiang Jiang, Kristen K Dang, 2021, PLoS Comput. Biol..

Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma

Jennifer D. Hintzsche, W. Robinson, M. Fujita, 2021, Molecular Cancer Therapeutics.

Enhanced immune activation within the tumor microenvironment and circulation of female high-risk melanoma patients and improved survival with adjuvant CTLA4 blockade compared to males

V. Sondak, J. Kirkwood, F. Hodi, 2022, Journal of translational medicine.

Advanced age is associated with changes in alveolar macrophages and their responses to the stress of traumatic injury

Devin M Boe, Rachel H. McMahan, A. Tan, 2022, Journal of leukocyte biology.

Systematic evaluation of the predictive gene expression signatures of immune checkpoint inhibitors in metastatic melanoma

Mengyu Xie, A. Tarhini, A. Tan, 2022, Molecular carcinogenesis.

The translational role of SOS1 in colorectal cancer

J. Fleming, M. Fernández-Zapico, Margaret A. Park, 2022, bioRxiv.

Development of SOS1 Inhibitor-Based Degraders to Target KRAS-Mutant Colorectal Cancer.

J. Fleming, W. Ma, M. Fernández-Zapico, 2022, Journal of medicinal chemistry.

Uncovering drug repurposing candidates for head and neck cancers: insights from systematic pharmacogenomics data analysis

S. Cheong, A. Tan, A. Chai, 2021, Scientific Reports.

Neoadjuvant endocrine therapy expands stromal populations that predict poor prognosis in estrogen receptor‐positive breast cancer

P. Kabos, C. Sartorius, S. Sams, 2021, Molecular carcinogenesis.

TIMEx: tumor-immune microenvironment deconvolution web-portal for bulk transcriptomics using pan-cancer scRNA-seq signatures

Mingxiang Teng, Kyubum Lee, Christine H. Chung, 2021, Bioinform..

ΔNp63 regulates a common landscape of enhancer associated genes in non-small cell lung cancer

Min Gyu Lee, K. Rajapakshe, C. Coarfa, 2022, Nature Communications.

Effects of Tobacco Smoking on the Tumor Immune Microenvironment in Head and Neck Squamous Cell Carcinoma

M. Schabath, C. Chung, R. Slebos, 2019, Clinical Cancer Research.

Summarizing internal dynamics boosts differential analysis and functional interpretation of super enhancers

B. Fridley, Mingxiang Teng, Derek R Duckett, 2021, bioRxiv.

Improved prognosis and evidence of enhanced immunogenicity in tumor and circulation of high-risk melanoma patients with unknown primary

V. Sondak, J. Kirkwood, P. Hwu, 2022, Journal for ImmunoTherapy of Cancer.

Deep Learning of Histopathology Images at the Single Cell Level

Kyubum Lee, Christine H. Chung, Elsa R. Flores, 2021, Frontiers in Artificial Intelligence.

DRPPM-PATH-SURVEIOR: Plug-and-Play Survival Analysis of Pathway-level Signatures and Immune Components

S. Eschrich, S. Meshinchi, Mingxiang Teng, 2023, Research square.

Pembrolizumab and cabozantinib in recurrent metastatic head and neck squamous cell carcinoma: a phase 2 trial

D. Shin, K. Magliocca, G. Chen, 2023, Nature Medicine.

Response to high dose ipilimumab plus temozolomide after progression on standard or low dose ipilimumab in advanced melanoma: a retrospective analysis

S. Hu-Lieskovan, T. Bowles, U. Swami, 2023, Research square.

The tumor microbiome as a predictor of outcomes in patients with metastatic melanoma treated with immune checkpoint inhibitors

M. McCarter, M. Churchman, Y. Zakharia, 2023, bioRxiv.

EGFR Inhibition by Cetuximab Modulates Hypoxia and IFN Response Genes in Head and Neck Squamous Cell Carcinoma

Ritu Chaudhary, Xuefeng Wang, J. Conejo-Garcia, 2023, Cancer research communications.

Translational relevance of SOS1 targeting for KRAS‐mutant colorectal cancer

J. Fleming, Margaret A. Park, Bhaswati Sarcar, 2023, Molecular carcinogenesis.

Grading of lung adenocarcinomas with simultaneous segmentation by artificial intelligence (GLASS-AI)

John H. Lockhart, O. Stringfield, M. Abdalah, 2023, NPJ precision oncology.

PATH-SURVEYOR: pathway level survival enquiry for immuno-oncology and drug repurposing

S. Eschrich, Mingxiang Teng, Xuefeng Wang, 2023, BMC Bioinformatics.

Real-world pan-cancer landscape of frameshift mutations and their role in predicting responses to immune checkpoint inhibitors in cancers with low tumor mutational burden

E. Sokol, G. Frampton, J. Trent, 2023, Journal for immunotherapy of cancer.

A bioinformatics tool for identifying intratumoral microbes from the ORIEN dataset

M. McCarter, M. Churchman, G. Riedlinger, 2023, bioRxiv.

Drepmel—A Multi-Omics Melanoma Drug Repurposing Resource for Prioritizing Drug Combinations and Understanding Tumor Microenvironment

K. Smalley, J. Teer, E. Welsh, 2022, Cells.

Enabling Precision Medicine in Cancer Care Through a Molecular Data Warehouse: The Moffitt Experience.

B. Fridley, S. Eschrich, E. Siegel, 2021, JCO Clinical Cancer Informatics.

PARP1 and POLD2 as prognostic biomarkers for multiple myeloma in autologous stem cell transplant

B. Fridley, C. Hofmeister, M. Poi, 2023, Haematologica.

EGFR Inhibition by Cetuximab Modulates Hypoxia and IFN Response Genes in Head and Neck Squamous Cell Carcinoma

Ritu Chaudhary, Xuefeng Wang, J. Conejo-Garcia, 2023, Cancer research communications.

Deciphering the Tumor–Immune–Microbe Interactions in HPV-Negative Head and Neck Cancer

D. Spakowicz, A. Tan, Min Hu, 2023, Genes.

Immune landscape in molecular subtypes of human papillomavirus‐negative head and neck cancer

J. Conejo-Garcia, Kyubum Lee, R. Slebos, 2023, Molecular carcinogenesis.