P. Mannucci

发表

The −308 G/A polymorphism in the tumor necrosis factor‐α gene is not associated with development and progression of rheumatoid arthritis in Argentinean patients

G. Citera, F. Aranda, S. Perés Wingeyer, 2016, International journal of rheumatic diseases.

Tissue plasminogen activator antigen is strongly associated with myocardial infarction in young women

L. Bernardinelli, L. Foco, M. Tubaro, 2005, Journal of thrombosis and haemostasis : JTH.

Changes in health and disease of the metalloprotease that cleaves von Willebrand factor.

P. Mannucci, E. Rossi, F. Lussana, 2001, Blood.

Measurement of von Willebrand factor cleaving protease (ADAMTS‐13): results of an international collaborative study involving 11 methods testing the same set of coded plasmas

J. Moake, K. Friedman, A. Tripodi, 2004, Journal of thrombosis and haemostasis : JTH.

Patients With Type 3 Severe von Willebrand Disease Are Not Protected Against Atherosclerosis: Results From a Multicenter Study in 47 Patients

F. Rosendaal, J. Reiber, M. Morfini, 2004, Circulation.

Desmopressin: an historical introduction

P. Mannucci, 2007, Haemophilia : the official journal of the World Federation of Hemophilia.

The risk of first venous thromboembolism during pregnancy and puerperium in double heterozygotes for factor V Leiden and prothrombin G20210A

P. Mannucci, E. Grandone, A. Tosetto, 2008, Journal of thrombosis and haemostasis : JTH.

Coinheritance of the HR2 Haplotype in the Factor V Gene Confers an Increased Risk of Venous Thromboembolism to Carriers of Factor V R506Q (Factor V Leiden)

M. Margaglione, P. Bucciarelli, G. Castaman, 1999 .

Hemophilia: treatment options in the twenty‐first century

P. Mannucci, 2003, Journal of thrombosis and haemostasis : JTH.

Immune tolerance induction with a high purity von Willebrand factor/VIII complex concentrate in haemophilia A patients with inhibitors at high risk of a poor response

P. Mannucci, M. Mazzucconi, A. Gringeri, 2007, Haemophilia : the official journal of the World Federation of Hemophilia.

Rare coagulation deficiencies

P. Mannucci, S. Duga, F. Peyvandi, 2002, Haemophilia : the official journal of the World Federation of Hemophilia.

Prevalence of type 2b ‘Malmö/New York’ von Willebrand disease in Italy: the role of von Willebrand factor gene conversion

G. Castaman, A. Federici, L. Baronciani, 2008, Journal of thrombosis and haemostasis : JTH.

Biochemical characterization of a recombinant von Willebrand factor (VWF) with combined type 2B and type 1 defects in the VWF gene in two patients with a type 2A phenotype of von Willebrand disease

A. Federici, L. Baronciani, M. Canciani, 2007, Journal of thrombosis and haemostasis : JTH.

Three novel PROC gene lesions causing protein C deficiency

A. Wacey, D. Bevan, L. Tengborn, 1998, Clinical genetics.

Back to the future: a recent history of haemophilia treatment

P. Mannucci, P. M. Mannucci, 2008, Haemophilia : the official journal of the World Federation of Hemophilia.

Genetic diagnosis of haemophilia and other inherited bleeding disorders

P. Mannucci, M. Chandy, S. Duga, 2006, Haemophilia : the official journal of the World Federation of Hemophilia.

Severe hemophilia with mild bleeding phenotype: molecular characterization and global coagulation profile

M. Clerici, P. Mannucci, E. Santagostino, 2010, Journal of thrombosis and haemostasis : JTH.

Health status and quality of life of elderly persons with severe hemophilia born before the advent of modern replacement therapy

P. Mannucci, E. Santagostino, M. Franchini, 2009, Journal of thrombosis and haemostasis : JTH.

Italian guidelines for the diagnosis and treatment of patients with haemophilia and inhibitors

P. Mannucci, A. Gringeri, P. Mannucci, 2005, Haemophilia : the official journal of the World Federation of Hemophilia.

Pharmacokinetic properties of IB1001, an investigational recombinant factor IX, in patients with haemophilia B: repeat pharmacokinetic evaluation and sialylation analysis

P. Mannucci, L. Valentino, M. Morfini, 2012, Haemophilia : the official journal of the World Federation of Hemophilia.

Cardiovascular disease in haemophilia patients: a contemporary issue

E. Mauser-Bunschoten, P. Mannucci, 2010, Haemophilia : the official journal of the World Federation of Hemophilia.

Deep intronic variations may cause mild hemophilia A

E. Santagostino, F. Rodeghiero, G. Castaman, 2011, Journal of thrombosis and haemostasis : JTH.

Tailoring hemostatic therapies to lower inhibitor development in previously untreated patients with severe hemophilia A

P. Mannucci, M. Franchini, P. Mannucci, 2016, Journal of thrombosis and haemostasis : JTH.

Thromboembolic incidence with transiently elevated levels of coagulation factors in patients with von Willebrand disease treated with VWF:FVIII concentrate during surgery

P. Mannucci, J. Gill, P. Mannucci, 2014, Haemophilia : the official journal of the World Federation of Hemophilia.

Severe factor V deficiency: exon skipping in the factor V gene causing a partial deletion of the C1 domain

S. Duga, F. Peyvandi, R. Asselta, 2003, Journal of thrombosis and haemostasis : JTH.

PCR analysis of HIV‐1 sequences and differential immunological features in seronegative and seropositive haemophiliacs

C. Peschle, G. Mariani, U. Testa, 1992, British journal of haematology.

Hepatitis C virus/human immunodeficiency virus coinfection in hemophiliacs: high rates of sustained virologic response to pegylated interferon and ribavirin therapy

M. Colombo, E. Santagostino, A. Coppola, 2009, Journal of thrombosis and haemostasis : JTH.

Low incidence of bleeding from HIV‐related thrombocytopenia in drug addicts and hemophiliacs: Implications for therapeutic strategies

T. Barbui, A. Lazzarin, A. Gringeri, 1990, European journal of haematology.

Role of the 2 adenine (g.11293_11294insAA) insertion polymorphism in the 3′ untranslated region of the factor VII (FVII) gene: molecular characterization of a patient with severe FVII deficiency

P. Mannucci, N. Marziliano, F. Peyvandi, 2005, Human mutation.

von Willebrand factor collagen binding assay in von Willebrand disease type 2A, 2B, and 2M

P. Mannucci, A. Federici, A. Federici, 2006, Journal of thrombosis and haemostasis : JTH.

Identification of differentially expressed genes in coronary atherosclerotic plaques from patients with stable or unstable angina by cDNA array analysis

M. Lennon, E. Bramucci, D. Ardissino, 2003, Journal of thrombosis and haemostasis : JTH.

Abnormalities of lymphocyte subsets are correlated with concentrate consumption in asymptomatic Italian hemophiliacs treated with concentrates made from American plasma

A. Gringeri, D. Mari, P. Mannucci, 1984, American journal of hematology.

Incidence of bleeding symptoms in 100 patients with inherited afibrinogenemia or hypofibrinogenemia

P. Mannucci, F. Peyvandi, S. Knaub, 2006, Journal of thrombosis and haemostasis : JTH.

Decrease and rapid recovery of protein C after plasma exchange

P. Walsh, P. Mannucci, J. Lewis, 1986, Transfusion.

The role of Willebrand factor in haemostasis and atherosclerosis

P. Mannucci, P. Mannucci, 1978, European journal of clinical investigation.

Fibrinolytic shut‐down after surgery: impairment of the balance between tissue‐type plasminogen activator and its specific inhibitor

P. Mannucci, J. Verheijen, C. Kluft, 1985, European journal of clinical investigation.

Abnormal hemostasis tests and bleeding in chronic liver disease: are they related? No

P. Mannucci, P. Mannucci, 2006, Journal of thrombosis and haemostasis : JTH.

Familial Overexpression of b Antithrombin Caused by an Asn 135 Thr Substitution

L. Hananeia, T. Bayston, H. Ireland, 1999 .

Low levels of protein Z and the risk of venous thromboembolism

I. Martinelli, P. Bucciarelli, C. Razzari, 2005, Journal of thrombosis and haemostasis : JTH.

Human parvovirus B19 infection in hemophiliacs first infused with two high‐purity, virally attenuated factor Vlll concentrates

P. Mannucci, G. Mariani, M. Morfini, 1992, American journal of hematology.

Novel investigations on the protective role of the FVIII/VWF complex in inhibitor development

P. Mannucci, P. Mannucci, R. Klamroth, 2014, Haemophilia : the official journal of the World Federation of Hemophilia.

Factor VIII products and inhibitor development: the SIPPET study (survey of inhibitors in plasma‐product exposed toddlers)

P. Mannucci, E. Santagostino, F. Peyvandi, 2007, Haemophilia : the official journal of the World Federation of Hemophilia.

Inhibitor development in previously treated hemophilia A patients: a systematic review, meta‐analysis, and meta‐regression

A. Iorio, P. Mannucci, M. Marcucci, 2013, Journal of thrombosis and haemostasis : JTH.

Effects of secondary prophylaxis started in adolescent and adult haemophiliacs

P. Mannucci, M. Franchini, C. Santoro, 2008, Haemophilia : the official journal of the World Federation of Hemophilia.

Opposite changes of ADAMTS‐13 and von Willebrand factor after cardiac surgery

P. Mannucci, M. Camera, A. Parolari, 2005, Journal of thrombosis and haemostasis : JTH.

Italian Registry of Haemophilia and Allied Disorders. Objectives, methodology and data analysis

M Morfini, P M Mannucci, A. Iorio, 2008, Haemophilia : the official journal of the World Federation of Hemophilia.

Activated partial thromboplastin time: results of a case–control study evaluating six commercial reagents in assessing the risk of venous thromboembolism

P. Mannucci, I. Martinelli, A. Tripodi, 2006, Journal of thrombosis and haemostasis : JTH.

Patterns of changes of anti‐ADAMTS13 after plasma exchange

I. Scharrer, F. Scheiflinger, P. Mannucci, 2006, Journal of thrombosis and haemostasis : JTH.

Molecular analysis of the genotype-phenotype relationship in factor X deficiency

D. Cooper, M. Krawczak, A. Wacey, 2000, Human Genetics.

Activated partial thromboplastin time (APTT). New indications for an old test?

P. Mannucci, A. Tripodi, P. Mannucci, 2006, Journal of thrombosis and haemostasis : JTH.

Expression studies on a novel type 2B variant of the von Willebrand factor gene (R1308L) characterized by defective collagen binding

A. Federici, L. Baronciani, M. Canciani, 2005, Journal of thrombosis and haemostasis : JTH.

No effect of polymorphisms in prothrombotic genes on the risk of myocardial infarction in young adults without cardiovascular risk factors

P. Mannucci, F. Rosendaal, C. Doggen, 2005, Journal of thrombosis and haemostasis : JTH.

AIDS, hepatitis and hemophilia in the 1980s: memoirs from an insider

P. Mannucci, P. Mannucci, 2003, Journal of thrombosis and haemostasis : JTH.

Thrombosis and bleeding disorders outside Western countries

P. Mannucci, P. Mannucci, 2007, Journal of thrombosis and haemostasis : JTH.

Second international collaborative study evaluating performance characteristics of methods measuring the von Willebrand factor cleaving protease (ADAMTS‐13)

B. Lämmle, S. Ferrari, P. Mannucci, 2008, Journal of thrombosis and haemostasis : JTH.

Molecular and phenotypic determinants of the response to desmopressin in adult patients with mild hemophilia A

P. Mannucci, E. Santagostino, A. Tosetto, 2009, Journal of thrombosis and haemostasis : JTH.

Fine particulate: it matters

P. Mannucci, P. Mannucci, 2010, Journal of thrombosis and haemostasis : JTH.

von Willebrand disease in the 21st century: current approaches and new challenges

P. Mannucci, C. Kessler, A. Federici, 2009, Haemophilia : the official journal of the World Federation of Hemophilia.

Quality of life is associated to the orthopaedic status in haemophilic patients with inhibitors

L. Mantovani, P. Mannucci, L. Scalone, 2006, Haemophilia : the official journal of the World Federation of Hemophilia.

I16 Hemophilia

P. Mannucci, P. Mannucci, 2007, Blood Reviews.

Nomenclature of Quantities and Units in Thrombosis and Haemostasis (Recommendation 1993)

M. Blombäck, C. Francis, B. Dahlbäck, 1994, Thrombosis and Haemostasis.

Is haemophilia B less severe than haemophilia A?

P. Mannucci, M. Franchini, P. Mannucci, 2013, Haemophilia : the official journal of the World Federation of Hemophilia.

von Willebrand factor/factor VIII concentrate (Haemate® P) dosing based on pharmacokinetics: a prospective multicenter trial in elective surgery

P. Mannucci, P. Kyrle, S. Lethagen, 2007, Journal of thrombosis and haemostasis : JTH.

More on: high thrombin generation and the risk of recurrent venous thromboembolism

P. Mannucci, C. Legnani, G. Palareti, 2009, Journal of thrombosis and haemostasis : JTH.

von Willebrand factor: what is its role in the immune response in haemophilia?

P. Mannucci, S. Kaveri, C. Kessler, 2011, Haemophilia : the official journal of the World Federation of Hemophilia.

Type and location of venous thromboembolism in patients with factor V Leiden or prothrombin G20210A and in those with no thrombophilia

P. Mannucci, I. Martinelli, T. Battaglioli, 2007, Journal of thrombosis and haemostasis : JTH.

Pharmacokinetic studies on Wilfactin®, a von Willebrand factor concentrate with a low factor VIII content treated with three virus‐inactivation/removal methods

P. Mannucci, A. Borel‐Derlon, J. Goudemand, 2005, Journal of thrombosis and haemostasis : JTH.

The natural history of occult or angiodysplastic gastrointestinal bleeding in von Willebrand disease

M. Makris, A. Federici, E. Berntorp, 2015, Haemophilia : the official journal of the World Federation of Hemophilia.

Q222R polymorphism in the DNAse I gene is not associated with susceptibility to rheumatoid arthritis or to disease course in an Argentine patient cohort

G. Camicia, G. Citera, F. Aranda, 2016 .

Different bleeding risk in type 2A and 2M von Willebrand disease: a 2‐year prospective study in 107 patients

P. Mannucci, A. Tosetto, F. Rodeghiero, 2012, Journal of thrombosis and haemostasis : JTH.

A multicenter pharmacokinetic study of the B‐domain deleted recombinant factor VIII concentrate using different assays and standards

P. Mannucci, M. Morfini, S. Cinotti, 2003, Journal of thrombosis and haemostasis : JTH.

Heterogeneity in type IIB von Willebrand disease: Two unrelated cases with no family history and mild abnormalities of ristocetin‐induced interaction between von willebrand factor and platelets

A. Federici, R. Lombardi, A. Lattuada, 1986 .

Precipitating antibodies in von Willebrand's disease

P. Mannucci, N. Ciavarella, J. Lavergne, 1976, Nature.

Results of a collaborative study for fibrinogen measurement. Evidence that the use of a common calibrator improves interlaboratory agreement

A. Tripodi, V. Chantarangkul, P. Mannucci, 1994, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Addressing current challenges in haemophilia care: consensus recommendations of a European Interdisciplinary Working Group

P. Mannucci, W. Powderly, C. Ludlam, 2005, Haemophilia : the official journal of the World Federation of Hemophilia.

Viral safety of coagulation factor concentrates: memoirs from an insider

P. Mannucci, P. Mannucci, 2018, Journal of thrombosis and haemostasis : JTH.

Allele Frequency of CYP2C9 Gene Polymorphisms in Iran

S. Zeinali, F. Peyvandi, M. Karimi, 2002, Thrombosis and Haemostasis.

Factor VIII inhibitors in previously treated hemophilic patients

P. Mannucci, P. Mannucci, 2011, Journal of thrombosis and haemostasis : JTH.

Need for randomized trials in hemophilia

P. Mannucci, P. Mannucci, 2006, Journal of thrombosis and haemostasis : JTH.

Expression studies of missense mutations p.D141Y, p.C275S located in the propeptide of von Willebrand factor in patients with type 3 von Willebrand disease

P. Mannucci, A. Federici, A. Federici, 2008, Haemophilia : the official journal of the World Federation of Hemophilia.

A critical role for Gly25 in the B chain of human thrombin

B. Villoutreix, M. Miteva, F. Peyvandi, 2005, Journal of thrombosis and haemostasis : JTH.

P. Mannucci, 1992, Thrombosis and Haemostasis.

Clinical manifestations and complications of childbirth and replacement therapy in 385 Iranian patients with type 3 von Willebrand disease

P. Mannucci, F. Peyvandi, P. Mannucci, 2000 .

Changing epidemiology of the hemolytic uremic syndrome and thrombotic thrombocytopenic purpura in southern Iran

F. Peyvandi, M. Karimi, P. Mannucci, 2006, Journal of thrombosis and haemostasis : JTH.

Effect of prothrombin 19911 A>G polymorphism on the risk of cerebral sinus‐venous thrombosis

P. Mannucci, A. Tosetto, I. Martinelli, 2010, European journal of neurology.

Factor VII gene polymorphisms are not associated with myocardial infarction in young women

L. Bernardinelli, P. Mannucci, F. Peyvandi, 2005, Journal of thrombosis and haemostasis : JTH.

Prothrombin A19911G polymorphism and the risk of venous thromboembolism

P. Mannucci, P. Mannucci, A. Tosetto, 2006, Journal of thrombosis and haemostasis : JTH.

Hepatocellular carcinoma in hemophilia

M. Colombo, P. Mannucci, D. Brettler, 1991, American journal of hematology.

Inhibitor development, immune tolerance and prophylaxis in haemophilia A – the need for an evidence‐based approach

P. Mannucci, E. Santagostino, V. Blanchette, 2006, Haemophilia.

Source and purity of factor VIII products as risk factors for inhibitor development in patients with hemophilia A

P. Mannucci, E. Santagostino, P. Mannucci, 2012, Journal of thrombosis and haemostasis : JTH.

A randomized, double‐blind comparison of two dosage levels of recombinant factor VIIa in the treatment of joint, muscle and mucocutaneous haemorrhages in persons with haemophilia A and B, with and without inhibitors

Shapiro, Kasper, Y. Laurian, 1998 .

The Outbreak of Hepatitis A in Italian Patients with Hemophilia: Facts and Fancies

P. Mannucci, E. Santagostino, M. Schiavoni, 1994, Vox sanguinis.

Haemophilia: strategies for carrier detection and prenatal diagnosis.

R. Ljung, D. Lillicrap, I. Peake, 1993, Bulletin of the World Health Organization.

A. Gringeri, S. von Mackensen, P. Mannucci, 2012, Haemophilia : the official journal of the World Federation of Hemophilia.

Desmopressin (DDAVP) and factor VIII: the tale as viewed from Milan (and Malmö)

P. Mannucci, P. Mannucci, 2003, Journal of thrombosis and haemostasis : JTH.

Non‐thrombotic‐, non‐inhibitor‐associated adverse reactions to coagulation factor concentrates for treatment of patients with hemophilia and von Willebrand’s disease: a systematic review of prospective studies

P. Mannucci, E. Santagostino, M. Franchini, 2012, Haemophilia : the official journal of the World Federation of Hemophilia.

Randomized double‐blind, placebo‐controlled trial of twice‐daily zidovudine in asymptomatic haemophiliacs infected with the human immunodeficiency virus type 1

A. Gringeri, P. Mannucci, Y. Laurian, 1994 .

Consistency of ADAMTS‐13 activity assays: a moderately optimistic view

P. Mannucci, 2003, Journal of thrombosis and haemostasis : JTH.

Antibody to Hepatitis G Mrus after a Vapour-Heated Factor Vlll Goncentrate

R. de Biasi, A. Zanetti, P. Mannucci, 1990, Thrombosis and Haemostasis.

Mutations in hemophilia Bm occur at the Arg180-Val activation site or in the catalytic domain of factor IX.

P. Reitsma, P. Mannucci, R. Bertina, 1990, The Journal of biological chemistry.

Plasma levels of active Von Willebrand factor are increased in patients with first ST-segment elevation myocardial infarction: A multicenter and multiethnic study

A. Maseri, A. Durante, A. Laricchia, 2015, European heart journal. Acute cardiovascular care.

High thrombin generation measured in the presence of thrombomodulin is associated with an increased risk of recurrent venous thromboembolism

P. Mannucci, B. Cosmi, C. Legnani, 2008, Journal of thrombosis and haemostasis : JTH.

Low risk of viral infection after administration of vapor‐heated factor VIII concentrate

P. Mannucci, D. Brettler, M. Hilgartner, 1992, Transfusion.

Outcome of Treatment of Deep-Vein Thrombosis with Urokinase: Relationship to Dosage, Duration of Therapy, Age of the Thrombus and Laboratory Changes

P. Mannucci, A. D’Angelo, P. Mannucci, 1984, Thrombosis and Haemostasis.

Hepatitis B vaccination of 113 hemophiliacs: Lower antibody response in anti‐LAV/HTLV‐III‐positive patients

A. Zanetti, E. Tanzi, A. Zanetti, 1986, American journal of hematology.

The first ambulatory screening on thromboembolism: a multicentre, cross‐sectional, observational study on risk factors for venous thromboembolism

P. Mannucci, M. Moia, G. Palareti, 2005, Journal of thrombosis and haemostasis : JTH.

High Frequency of the C677T Mutation in the Methylenetetrahydrofolate Reductase (MTHFR) Gene in Northern Italy

E. Sacchi, P. Mannucci, P. Mannucci, 1997, Thrombosis and Haemostasis.

The International Society for Thrombosis and Haemostasis owns its official journal: the future has begun!

P. Mannucci, 2003 .

Autopsy Findings in Three Patients with von Willebrand Disease Type IIB and Type III: Presence of Atherosclerotic Lesions without Occlusive Arterial Thrombi

A. Federici, P. Mannucci, A. Federici, 1993, Thrombosis and Haemostasis.

Rate of inhibitor development in previously untreated hemophilia A patients treated with plasma‐derived or recombinant factor VIII concentrates: a systematic review

A. Iorio, M. Marcucci, E. Santagostino, 2010, Journal of thrombosis and haemostasis : JTH.

Cardiovascular disease in haemophilia patients: a contemporary issue

E. Mauser-Bunschoten, P. Mannucci, 2010, Haemophilia : the official journal of the World Federation of Hemophilia.

Recombinant porcine factor VIII: a new instalment of a long story

P. Mannucci, P. Mannucci, 2015, Haemophilia : the official journal of the World Federation of Hemophilia.