J. Beckel

发表

The P2X7 receptor links mechanical strain to cytokine IL‐6 up‐regulation and release in neurons and astrocytes

A. Laties, C. Mitchell, Wennan Lu, 2017, Journal of neurochemistry.

TRP Channel Agonists Activate Different Afferent Neuromodulatory Mechanisms in Guinea Pig Urinary Bladder

W. D. de Groat, B. Freeman, J. Beckel, 2021, Frontiers in Physiology.

Involvement of TRPM4 in detrusor overactivity following spinal cord transection in mice

A. Kanai, W. D. de Groat, L. Birder, 2018, Naunyn-Schmiedeberg's Archives of Pharmacology.

Pannexin 1 channels mediate the release of ATP into the lumen of the rat urinary bladder

W. C. Groat, L. Birder, C. Mitchell, 2015, The Journal of physiology.

Differential expression and function of nicotinic acetylcholine receptors in the urinary bladder epithelium of the rat

L. Birder, J. Beckel, 2012, The Journal of physiology.

Neuroanatomy of the lower urinary tract.

Gert Holstege, G. Holstege, Jonathan M Beckel, 2011, Handbook of experimental pharmacology.

Stimulation of TLR3 triggers release of lysosomal ATP in astrocytes and epithelial cells that requires TRPML1 channels

C. Mitchell, K. Boesze-Battaglia, Wennan Lu, 2018, Scientific Reports.

Analysis of the afferent limb of the vesicovascular reflex using neurotoxins, resiniferatoxin and capsaicin.

W. D. de Groat, M. Chancellor, M. Fraser, 2001, American journal of physiology. Regulatory, integrative and comparative physiology.

Polarized Cytokine Release Triggered by P2X7 Receptor from Retinal Pigmented Epithelial Cells Dependent on Calcium Influx

C. Mitchell, Wenli Yang, J. Mills, 2020, Cells.

Non-neuronal acetylcholine and urinary bladder urothelium.

A. Kanai, W. D. de Groat, L. Birder, 2007, Life sciences.

Issue Information

S. Sharma, R. Shivdasani, L. Birder, 2015 .

Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium.

L. Birder, G. Apodaca, R. Rojas, 2004, American journal of physiology. Renal physiology.

Bladder Underactivity Induced by Prolonged Pudendal Afferent Activity in Cats.

W. D. de Groat, C. Tai, Jialiang Chen, 2020, American journal of physiology. Regulatory, integrative and comparative physiology.

Superficial peroneal neuromodulation of nonobstructive urinary retention in cats

W. D. de Groat, C. Tai, Jialiang Chen, 2020, Neurourology and urodynamics.

Involvement of TRPM4 in detrusor overactivity following spinal cord transection in mice

A. Kanai, W. D. de Groat, L. Birder, 2018, Naunyn-Schmiedeberg's Archives of Pharmacology.

Expression and function of rat urothelial P 2 Y receptors

A. Ford, L. Birder, A. Hanna-Mitchell, 2008 .

LPS‐mediated release of ATP from urothelial cells occurs by lysosomal exocytosis

W. D. de Groat, J. Beckel, S. Daugherty, 2020, Neurourology and urodynamics.

Vaginal Lubrication and Pressure Increase Induced by Pudendal Nerve Stimulation in Cats.

W. D. de Groat, C. Tai, C. Chermansky, 2022, The journal of sexual medicine.

Intracellular sodium concentration and membrane potential oscillation in axonal conduction block induced by high-frequency biphasic stimulation

W. D. de Groat, C. Tai, J. Beckel, 2022, Journal of neural engineering.

High-frequency stimulation induces axonal conduction block without generating initial action potentials

W. D. de Groat, C. Tai, Jicheng Wang, 2021, Journal of Computational Neuroscience.

Mechanisms Underlying Poststimulation Block Induced by High-Frequency Biphasic Stimulation.

W. D. de Groat, C. Tai, Jicheng Wang, 2021, Neuromodulation : journal of the International Neuromodulation Society.

The Lower Urinary Tract

G. Holstege, J. Beckel, 2015 .

Expression and function of urothelial nicotinic acetylcholine receptors

J. Beckel, 2009 .

The P2X7 Receptor Primes IL-1β and the NLRP3 Inflammasome in Astrocytes Exposed to Mechanical Strain

C. Mitchell, S. McCaughey, Wennan Lu, 2017, Front. Cell. Neurosci..

Mechanosensitive release of adenosine 5′‐triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: A mechanism for purinergic involvement in chronic strain

V. Sheffield, A. Laties, C. Mitchell, 2014, Glia.

Neurons respond directly to mechanical deformation with pannexin‐mediated ATP release and autostimulation of P2X7 receptors

A. Laties, C. Mitchell, E. Macarak, 2012, The Journal of physiology.

Expression of functional nicotinic acetylcholine receptors in rat urinary bladder epithelial cells.

A. Kanai, W. D. de Groat, L. Birder, 2006, American journal of physiology. Renal physiology.

Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception

G. Apodaca, D. Clayton, W. Ruiz, 2021, JCI insight.

L. Birder, G. Apodaca, J. Yabes, 2018, PloS one.

Neurophysiology of the lower urinary tract.

Gert Holstege, G. Holstege, Jonathan M Beckel, 2011, Handbook of experimental pharmacology.

Expression and function of bradykinin B1 and B2 receptors in normal and inflamed rat urinary bladder urothelium

A. Ford, W. D. de Groat, L. Birder, 2005, The Journal of physiology.

Heterogeneity of muscarinic receptor-mediated Ca2+ responses in cultured urothelial cells from rat.

W. D. de Groat, L. Birder, J. Beckel, 2008, American journal of physiology. Renal physiology.

CAKUT and Autonomic Dysfunction Caused by Acetylcholine Receptor Mutations.

Richard S. Lee, S. Mane, S. Ellard, 2019, American journal of human genetics.

Activation of TRPM8 channel inhibits contraction of the isolated human ureter

J. Beckel, S. Daugherty, Jiaxin Liu, 2021, Neurourology and urodynamics.

Defecation Induced by Stimulation of Sacral S2 Spinal Root in Cats.

W. D. de Groat, C. Tai, C. Chermansky, 2021, American journal of physiology. Gastrointestinal and liver physiology.

Expression and function of rat urothelial P2Y receptors.

A. Ford, L. Birder, A. Hanna-Mitchell, 2008, American journal of physiology. Renal physiology.

responses in cultured urothelial cells from rat 2+ Heterogeneity of muscarinic receptor-mediated Ca

L. Birder, A. Hanna-Mitchell, G. Ruiz, 2013 .

Treating Lower Urinary Tract Symptoms in Older Adults: Intravesical Options

A. Kanai, M. Chancellor, N. Yoshimura, 2023, Drugs & Aging.

Neuronal Release of Cytokine IL-3 Triggered by Mechanosensitive Autostimulation of the P2X7 Receptor Is Neuroprotective

C. Mitchell, Wennan Lu, J. Beckel, 2016, Front. Cell. Neurosci..

Excitatory effect of biphasic kHz field stimulation on CA1 pyramidal neurons in slices

S. Karnup, W. D. de Groat, C. Tai, 2021, bioRxiv.

Stimulation of TLR3 triggers release of lysosomal ATP in astrocytes and epithelial cells that requires TRPML1 channels

C. Mitchell, K. Boesze-Battaglia, Wennan Lu, 2018, Scientific Reports.

Lysosomal alkalinization, lipid oxidation, and reduced phagosome clearance triggered by activation of the P2X7 receptor

A. Laties, A. O’Brien-Jenkins, C. Mitchell, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Approaches for detecting lysosomal alkalinization and impaired degradation in fresh and cultured RPE cells: evidence for a role in retinal degenerations.

A. Laties, C. Mitchell, K. Boesze-Battaglia, 2014, Experimental eye research.

Low pressure voiding induced by stimulation and 1 kHz post-stimulation block of the pudendal nerves in cats

W. C. Groat, C. Tai, Jialiang Chen, 2021, Experimental Neurology.

Effect of high‐frequency membrane potential alternation between depolarization and hyperpolarization on dorsal root ganglion neurons of rats

W. D. de Groat, C. Tai, J. Beckel, 2023, Physiological reports.

Model Analysis of Post-Stimulation Effect on Axonal Conduction and Block

Changfeng Tai, Yihua Zhong, Jicheng Wang, 2021, IEEE Transactions on Biomedical Engineering.

Pudendal Nerve Block by Low‐Frequency (≤1 kHz) Biphasic Electrical Stimulation

W. D. de Groat, C. Tai, Jicheng Wang, 2020, Neuromodulation : journal of the International Neuromodulation Society.

Mo2041 Effect of Ibodutant, a Neurokinin NK2 Receptor Antagonist, on Gender-Related Influences Following Induction of Trinitrobenzenesulfonic Acid-Induced Colitis in the Guinea Pig

A. Kanai, L. Birder, C. Maggi, 2015 .

Activation of TRPC channels contributes to OA‐NO2‐induced responses in guinea‐pig dorsal root ganglion neurons

W. D. de Groat, B. Freeman, S. Woodcock, 2014, The Journal of physiology.

The effect of the electrophilic fatty acid nitro-oleic acid on TRP channel function in sensory neurons.

W. D. de Groat, J. Beckel, 2018, Nitric oxide : biology and chemistry.

Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer’s disease-linked presenilin 1 A246E mutation can be reversed with cAMP

A. Laties, C. Mitchell, J. Beckel, 2014, Neuroscience.

Heterogeneity of muscarinic receptor-mediated Ca2+ responses in cultured urothelial cells from rat.

J. Beckel, F. Kullmann, D. Artim, 2008, American journal of physiology. Renal physiology.

Lysosomal alkalinization, lipid oxidation, and reduced phagosome clearance triggered by activation of the P2X7 receptor

A. Laties, A. O’Brien-Jenkins, C. Mitchell, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Role of opioid and β‐adrenergic receptors in bladder underactivity induced by prolonged pudendal nerve stimulation in cats

W. D. de Groat, C. Tai, C. Chermansky, 2023, Neurourology and urodynamics.

Purinergic signaling promotes premature senescence

M. Trebak, D. Volonté, Ferruccio Galbiati, 2024, The Journal of biological chemistry.

Pudendal Nerve Block by Adaptively Stepwise Increasing the Intensity of High-Frequency (10 kHz) Biphasic Stimulation.

W. D. de Groat, C. Tai, Jicheng Wang, 2023, Neuromodulation : journal of the International Neuromodulation Society.

Sex differences in lower urinary tract function in mice with or without spinal cord injury

W. D. de Groat, H. Uemura, J. Beckel, 2023, Neurourology and urodynamics.