W. Lynch

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Unique N-Linked Glycosylation of CasBrE Env Influences Its Stability, Processing, and Viral Infectivity but Not Its Neurotoxicity

Russell S. Traister, K. Renszel, W. Lynch, 2013, Journal of Virology.

Phosphorylation of hnRNP L Is Modulated by AKT-dependent hnRNP U Enhances Caspase-9 Splicing and RNA:

Ngoc Thang Vu, Sarah A. Smith, C. Chalfant, 2013 .

Dissecting the determinants of neuropathogenesis of the murine oncornaviruses.

J. Portis, W. Lynch, 1998, Virology.

Differential Glycosylation of the Cas-Br-E Env Protein Is Associated with Retrovirus-Induced Spongiform Neurodegeneration

A. Sharpe, W. Lynch, 2000, Journal of Virology.

Induction of focal spongiform neurodegeneration in developmentally resistant mice by implantation of murine retrovirus-infected microglia

J. Portis, S. Robertson, W. Lynch, 1995, Journal of virology.

Misfolding of CasBrE SU is reversed by interactions with 4070A Env: implications for gammaretroviral neuropathogenesis

Y. Li, W. Lynch, 2010, Retrovirology.

Rebound from Inhibition: Self-Correction against Neurodegeneration?

S. Sivaramakrishnan, W. Lynch, Shobhana Sivaramakrishnan, 2017, Journal of clinical & cellular immunology.

Gene expression profiling of microglia infected by a highly neurovirulent murine leukemia virus: implications for neuropathogenesis

L. G. Volkert, Y. Li, A. Delucia, 2006, Retrovirology.

Retrovirus-Induced Spongiform Neurodegeneration Is Mediated by Unique Central Nervous System Viral Targeting and Expression of Env Alone

Y. Li, Russell S. Traister, Sandra M. Cardona, 2010, Journal of Virology.

Late virus replication events in microglia are required for neurovirulent retrovirus-induced spongiform neurodegeneration: evidence from neural progenitor-derived chimeric mouse brains

E. Snyder, A. Sharpe, J. Portis, 1996, Journal of virology.

Kinetic analysis of spongiform neurodegenerative disease induced by a highly virulent murine retrovirus.

J. Portis, M. Czub, W. Lynch, 1994, Laboratory investigation; a journal of technical methods and pathology.

Murine retrovirus-induced spongiform encephalopathy: Productive infection of microglia and cerebellar neurons in accelerated CNS disease

S. F. Hayes, J. Portis, F. McAtee, 1991, Neuron.

α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss

S. Lipton, J. Kelly, Yvonne S. Eisele, 2021, The Journal of Neuroscience.

Reexamination of amphotropic murine leukemia virus neurovirulence: neural stem cell-mediated microglial infection fails to induce acute neurodegeneration.

Russell S. Traister, W. Lynch, 2002, Virology.

Inhibition of murine retrovirus-induced neurodegeneration in the spinal cord by explant culture

J. Portis, R. Bessen, W. Lynch, 1995, Journal of virology.

Murine retrovirus-induced spongiform encephalopathy: disease expression is dependent on postnatal development of the central nervous system

J. Portis, C. Garon, S. Czub, 1993, Journal of virology.

Prevention of retrovirus-induced neurological disease by infection with a nonneuropathogenic retrovirus.

J. Portis, F. McAtee, M. Czub, 1995, Virology.

Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons

Melitta Schachner, M. Schachner, E. Snyder, 2002, Nature Biotechnology.

Neural Stem Cells as Engraftable Packaging Lines Can Mediate Gene Delivery to Microglia: Evidence from Studying Retroviral env-Related Neurodegeneration

E. Snyder, A. Sharpe, W. Lynch, 1999, Journal of Virology.

Neural stem cells as tools for understanding retroviral neuropathogenesis.

J. Portis, W. Lynch, 2000, Virology.

Identification and localization of immunoreactive forms of caldesmon in smooth and nonmuscle cells: a comparison with the distributions of tropomyosin and alpha-actinin

A. Bretscher, W. Lynch, 1985, The Journal of cell biology.

Rabies viruses infect primary cultures of murine, feline, and human microglia and astrocytes

C. Power, N. B. Ray, W. Lynch, 2014, Archives of Virology.

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4.

J. Bluestone, A. Sharpe, A. Schweitzer, 1995, Immunity.

Contribution to Excitability Hypothalamic Neurons: Calcium Channel Biophysical Characterization of Rat Caudal

M. A. Masino, S. Grillner, P. Wallén, 2015 .

The calmodulin and F-actin binding sites of smooth muscle caldesmon lie in the carboxyl-terminal domain whereas the molecular weight heterogeneity lies in the middle of the molecule.

A. Bretscher, W. Lynch, V. M. Riseman, 1989, The Journal of biological chemistry.

Smooth muscle caldesmon is an extended flexible monomeric protein in solution that can readily undergo reversible intra- and intermolecular sulfhydryl cross-linking. A mechanism for caldesmon's F-actin bundling activity.

A. Bretscher, W. Lynch, V. M. Riseman, 1987, The Journal of biological chemistry.

Purification of caldesmon.

A. Bretscher, W. Lynch, 1986, Methods in enzymology.

A plant lignan, 3′‐O‐Methyl‐Nordihydroguaiaretic acid, suppresses papillomavirus E6 protein function, stabilizes p53 protein, and induces apoptosis in cervical tumor cells

A. Delucia, W. Lynch, K. Awad, 2007, Molecular carcinogenesis.

E. Snyder, A. Sharpe, W. Lynch, 1999 .

Microglial infection by a neurovirulent murine retrovirus results in defective processing of envelope protein and intracellular budding of virus particles

J. Portis, G. Spangrude, W. Lynch, 1994, Journal of virology.

Cross‐Talk Between Stem Cells and the Dysfunctional Brain is Facilitated by Manipulating the Niche: Evidence from an Adhesion Molecule

M. Schachner, E. Snyder, V. Ourednik, 2009, Stem cells.

Ecotropic Murine Leukemia Virus Infection of Glial Progenitors Interferes with Oligodendrocyte Differentiation: Implications for Neurovirulence

Sandra M. Cardona, W. Macklin, C. Pedraza, 2016, Journal of Virology.

Astrocyte Infection Is Required for Retrovirus-Induced Spongiform Neurodegeneration Despite Suppressed Viral Protein Expression

Sandra M. Cardona, Alvin S. Das, W. Lynch, 2019, Front. Neurosci..

Ecotropic Murine Leukemia Virus Infection of Glial Progenitors Interferes with Oligodendrocyte 1 Differentiation : Implications for Neurovirulence 2 3 Running title : MLVs inhibit oligodendrocyte differentiation

Sandra M. Cardona, W. Macklin, C. Pedraza, 2016 .

Postinhibitory rebound neurons and networks are disrupted in retrovirus-induced spongiform neurodegeneration.

Y. Li, R. Davey, S. Sivaramakrishnan, 2014, Journal of neurophysiology.

Gene expression profiling of microglia infected by a highly neurovirulent murine leukemia virus: implications for neuropathogenesis

Y. Li, A. Delucia, W. Lynch, 2005, Retrovirology.