S. Ruuls

发表

Unlinking tumor necrosis factor biology from the major histocompatibility complex: lessons from human genetics and animal models.

J. Sedgwick, S. Ruuls, 1999, American journal of human genetics.

IMMUNOGENETICS '99 Unlinking Tumor Necrosis Factor Biology from the Major Histocompatibility Complex: Lessons from Human Genetics and Animal Models

J. Sedgwick, S. Ruuls, 1999 .

TNF deficiency dysregulates inflammatory cytokine production leading to lung pathology and death during respiratory poxvirus infection

T. Newsome, G. Karupiah, G. Chaudhri, 2019, bioRxiv.

Cytokine‐directed therapies in multiple sclerosis and experimental autoimmune encephalomyelitis

J. Sedgwick, S. Ruuls, 1998, Immunology and cell biology.

Interferon-β directly influences monocyte infiltration into the central nervous system

A. Wierinckx, C. Dijkstra, S. Ruuls, 2002, Journal of Neuroimmunology.

Induction of nitric oxide synthase in multiple sclerosis lesions

C. Dijkstra, P. Valk, S. Ruuls, 1997 .

Immunocytochemical Characterization of the Expression of Inducible and Constitutive Isoforms of Nitric Oxide Synthase in Demyelinating Multiple Sclerosis Lesions

C. D. DE GROOT, C. Dijkstra, S. Ruuls, 1997, Journal of neuropathology and experimental neurology.

A population of interstitial cells in the anterior pituitary with a hematopoietic origin and a rapid turnover: a relationship with folliculo–stellate cells?

D. Klatzmann, H. Drexhage, B. Salomon, 1997, Journal of Neuroimmunology.

Macrophages in T cell line‐mediated, demyelinating, and chronic relapsing experimental autoimmune encephalomyelitis in Lewis rats

Steffen Jung, H. Hartung, N. Rooijen, 1995, Clinical and experimental immunology.

Experimental Allergic Encephalomyelitis

I. Huitinga, C. Dijkstra, J. Bauer, 1997 .

Infection Mycobacterium tuberculosis Control of and Provide Acute, but Not Long-Term, Cell Migration and Granuloma Formation Transmembrane TNF Is Sufficient to Initiate

W. Britton, B. Saunders, J. Sedgwick, 2005 .

Interferon-beta directly influences monocyte infiltration into the central nervous system.

H. D. de Vries, A. Wierinckx, S. V. D. van der Pol, 2002, Journal of neuroimmunology.

Beneficial effect of modified peptide inhibitor of α4 integrins on experimental allergic encephalomyelitis in Lewis rats

M. Wauben, T. Kuijpers, M. Elices, 2002, Journal of neuroscience research.

The length of treatment determines whether IFN-beta prevents or aggravates experimental autoimmune encephalomyelitis in Lewis rats.

T. Olsson, C. Dijkstra, P. H. van der Meide, 1996, Journal of immunology.

The role of macrophages in different stages of experimental allergic encephalomyelitis in Lewis rats

I. Huitinga, C. Dijkstra, S. Ruuls, 1992 .

Systematic study of tissue factor expression in solid tumors

I. Vergote, J. D. de Bono, R. Christova, 2022, Cancer reports.

Down-regulation of the macrophage lineage through interaction with OX2 (CD200).

B. Blom, W. Streit, A. Barclay, 2000, Science.

Discontinuation of treatment with IFN-β leads to exacerbation of experimental autoimmune encephalomyelitis in Lewis rats. Rapid reversal of the antiproliferative activity of IFN-β and excessive expansion of autoreactive T cells as disease promoting mechanisms

T. Olsson, C. Dijkstra, S. Ruuls, 1998, Journal of Neuroimmunology.

Complement in therapy and disease: Regulating the complement system with antibody-based therapeutics.

P. Parren, J. Schuurman, Kristin Strumane, 2015, Molecular immunology.

The role of macrophage subpopulations in autoimmune disease of the central nervous system

I. Huitinga, C. Dijkstra, J. Bauer, 1996, The Histochemical Journal.

TNF deficiency dysregulates inflammatory cytokine production, leading to lung pathology and death during respiratory poxvirus infection

T. Newsome, G. Karupiah, G. Chaudhri, 2020, Proceedings of the National Academy of Sciences.

Macrophage phagocytosis of myelin in vitro determined by flow cytometry: phagocytosis is mediated by CR3 and induces production of tumor necrosis factor-α and nitric oxide

L. Laan, E. Döpp, C. Dijkstra, 1996, Journal of Neuroimmunology.

Novel human antibody therapeutics: The age of the Umabs

P. Parren, J. V. D. van de Winkel, J. V. van Bueren, 2008, Biotechnology journal.

A Critical Role for Interleukin 18 in Primary and Memory Effector Responses to Listeria monocytogenes That Extends Beyond Its Effects on Interferon γ Production

R. Kastelein, J. Bazan, J. Abrams, 2001, The Journal of experimental medicine.

Transmembrane TNF Is Sufficient to Initiate Cell Migration and Granuloma Formation and Provide Acute, but Not Long-Term, Control of Mycobacterium tuberculosis Infection1

W. Britton, B. Saunders, J. Sedgwick, 2005, The Journal of Immunology.

Immunogenicity of anti-tumor necrosis factor antibodies-toward improved methods of anti-antibody measurement.

L. Aarden, G. Wolbink, S. Ruuls, 2008, Current opinion in immunology.

β-Adrenoceptor-sensitive adenylate cyclase is inhibited by activation of μ-opioid receptors in rat striatal neurons

B. Drukarch, A. Schoffelmeer, A. H. Mulder, 1991 .

Aggravation of experimental allergic encephalomyelitis (EAE) by administration of nitric oxide (NO) synthase inhibitors

S. Linden, I. Huitinga, C. Dijkstra, 1996, Clinical and experimental immunology.

Membrane-bound TNF supports secondary lymphoid organ structure but is subservient to secreted TNF in driving autoimmune inflammation.

J. Cyster, V. Ngo, R. Hoek, 2001, Immunity.

Opening the door to innovation

P. Parren, A. Labrijn, J. Schuurman, 2014, mAbs.

Reactive oxygen species are involved in the pathogenesis of experimental allergic encephalomyelitis in Lewis rats

Christine D. Dijkstra, I. Huitinga, C. Dijkstra, 1995, Journal of Neuroimmunology.

Complement activation impacts B-cell depletion by both type I and type II CD20 monoclonal antibodies.

P. Parren, T. Vink, J. V. D. van de Winkel, 2008, Blood.

II CD20 monoclonal antibodies Complement activation impacts B-cell depletion by both type I and type

P. Parren, T. Vink, F. Beurskens, 2008 .

Nitric Oxide in the Central Nervous System of Rats Suffering from Rabies Virus Infection or Experimental Allergic Encephalomyelitis

C. Marquette, C. Dijkstra, J. Bauer, 1997 .