D. Cavender

发表

Endothelial cell activation induced by tumor necrosis factor and lymphotoxin.

M. Ziff, D. Edelbaum, D. Cavender, 1989, The American journal of pathology.

T-cell adhesion to endothelial cells in systemic lupus erythematosus

D. Haskard, M. Ziff, D. Cavender, 2004, Rheumatology International.

The pittsburgh diabetes mellitus study

L. Kuller, D. Wagener, R. LaPorte, 1983, Diabetologia.

Height at diagnosis of insulin dependent diabetes in patients and their non-diabetic family members.

K. Cruickshanks, M. Eberhardt, N. Tajima, 1986, British medical journal.

Glucose tolerance in siblings of Type 1 diabetic patients relationship to HLA status

L. Kuller, D. Wagener, B. Rabin, 2006, Diabetologia.

Pittsburgh Insulin-Dependent Diabetes Mellitus Morbidity and Mortality Study: physical activity and diabetic complications.

K. Cruickshanks, N. Tajima, R. LaPorte, 1986, Pediatrics.

Presence of complement-dependent cytotoxic activity against clonally-derived rat islet tumour cells in sera from Type 1 (insulin-dependent) diabetic patients and control subjects

M. Virji, D. Cavender, S. Holze-Joost, 1986, Diabetologia.

Correlates of Insulin Antibodies in Newly Diagnosed Children with Insulin-dependent Diabetes Before Insulin Therapy

M. Eberhardt, B. Rabin, J. Dorman, 1985, Diabetes.

Organ-Specific and Non-Organ-Specific Receptors for Vascular Endothelium Lymphocyte

D. Cavender, 1990 .

Organ-specific and non-organ-specific lymphocyte receptors for vascular endothelium.

D. Cavender, 1990, The Journal of investigative dermatology.

Production of interleukin 1 by human endothelial cells.

P. Miossec, M. Ziff, D. Cavender, 1986, Journal of immunology.

Interactions between endothelial cells and the cells of the immune system.

D. Cavender, Druie E. Cavender, 1991, International review of experimental pathology.

HLA Heterogeneity of Insulin-dependent Diabetes Mellitus at Diagnosis: The Pittsburgh IDDM Study

L. Kuller, D. Wagener, M. Eberhardt, 1985, Diabetes.

Familial and sporadic insulin-dependent diabetes: evidence for heterogeneous etiologies?

L. Kuller, M. Eberhardt, B. Rabin, 1991, Diabetes research and clinical practice.

p38 Mitogen-activated protein kinase as a target for drug discovery

S. Wadsworth, D. Cavender, J. R. Henry, 1999 .

Pittsburgh Diabetes Mellitus Study: Studies on the Etiology of Insulin‐Dependent Diabetes Mellitus with Special Reference to Viral Infections

L. Kuller, D. Wagener, M. Eberhardt, 1984, Behring Institute Mitteilungen.

Multivariate analyses of the risk of insulin-dependent diabetes mellitus for siblings of insulin-dependent diabetic patients.

L. Kuller, D. Wagener, R. LaPorte, 1984, American Journal of Epidemiology.

A kinase-dead knock-in mutation in mTOR leads to early embryonic lethality and is dispensable for the immune system in heterozygous mice

Crafford A. Harris, D. Cavender, Boris Shor, 2009, BMC Immunology.

Stimulation of endothelial cell binding of lymphocytes by tumor necrosis factor.

Y. Saegusa, M. Ziff, D. Cavender, 1987, Journal of immunology.

T lymphocyte adhesion to endothelial cells: mechanisms demonstrated by anti-LFA-1 monoclonal antibodies.

T. Springer, D. Haskard, M. Ziff, 1986, Journal of immunology.

Effects of Inflammatory Cytokines and Phorbol Esters on the Adhesion of U937 Cells, a Human Monocyte‐Like Cell Line, to Endothelial Cell Monolayers and Extracellular Matrix Proteins

D. Edelbaum, D. Cavender, L. Welkovich, 1991, Journal of leukocyte biology.

Immunomodulation and adenoviral gene transfer to the lungs of nonhuman primates.

D. Sullivan, J. Shellito, J. Kolls, 2000, Human gene therapy.

Interleukin 1 increases the binding of human B and T lymphocytes to endothelial cell monolayers.

D. Haskard, M. Ziff, D. Cavender, 1986, Journal of immunology.

Mechanisms of Lymphocyte Adhesion to Endothelial Cells

D. Haskard, M. Ziff, D. Cavender, 1987 .

Interleukin (IL)-1 Receptor–associated Kinase (IRAK) Requirement for Optimal Induction of Multiple IL-1 Signaling Pathways and IL-6 Production

Crafford A. Harris, P. A. Peterson, W. Fung-Leung, 1998, The Journal of experimental medicine.

Superinduction of T lymphocyte-endothelial cell (EC) binding by treatment of EC with interleukin 1 and protein synthesis inhibitors.

D. Haskard, M. Ziff, D. Cavender, 1987, Journal of immunology.

Inhibition by IL-1 of endothelial cell activation induced by tumor necrosis factor or lymphotoxin.

D. Edelbaum, D. Cavender, 1988, Journal of immunology.

Synthesis and structure-activity relationship of 7-azaindole piperidine derivatives as CCR2 antagonists.

W. Murray, M. Singer, Scott R Pollack, 2008, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of phenyl piperidine derivatives as CCR2 antagonists.

M. Singer, Scott R Pollack, D. Cavender, 2007, Bioorganic & medicinal chemistry letters.

T cell adhesion to extracellular matrix molecules secreted by endothelial cells cultured on a substrate of type IV collagen.

D. Cavender, J. Cearns-Spielman, C. Barrus, 1991, Journal of immunological methods.

Development of a sensitive and HTS-compatible reporter gene assay for functional analysis of human adenosine A2a receptors in CHO-K1 cells.

M. Wildey, K. Demarest, Yuting Tang, 2004, Assay and drug development technologies.

Different approaches to study mast cell functions.

R. Malaviya, D. Cavender, R. Sur, 2007, International immunopharmacology.

Potent and selective CC-chemokine receptor-2 (CCR2) antagonists as a potential treatment for asthma.

B. Lagu, M. Singer, R. Malaviya, 2007, Bioorganic & medicinal chemistry letters.

INTERFERON-? INCREASES SUSCEPTIBILITY OF MURINE PANCREATIC BETA CELLS TO LYSIS BY ALLOGENEIC CYTOTOXIC T LYMPHOCYTES

D. Cavender, P. Wood, J. Cearns-Spielman, 1990 .

Effect of inflammatory cytokines on human endothelial cell proliferation

Y. Saegusa, M. Ziff, D. Cavender, 1990, Journal of cellular physiology.

Synthesis, structure-activity relationship and in vivo antiinflammatory efficacy of substituted dipiperidines as CCR2 antagonists.

Nareshkumar Jain, M. Singer, Scott R Pollack, 2007, Journal of medicinal chemistry.

Phorbol ester-stimulated T lymphocytes show enhanced adhesion to human endothelial cell monolayers.

D. Haskard, M. Ziff, D. Cavender, 1986, Journal of immunology.

Human gamma interferon increases the binding of T lymphocytes to endothelial cells.

C. Yu, D. Haskard, A. Johnson, 1985, Clinical and experimental immunology.

Anti-HLA-B27 antibodies in sera from patients with gram-negative bacterial infections.

M. Ziff, D. Cavender, 1986, Arthritis and rheumatism.

Human dermal microvascular endothelial cells behave like umbilical vein endothelial cells in T-cell adhesion studies.

D. Haskard, R. Sontheimer, M. Ziff, 1987, The Journal of investigative dermatology.

Nitroarylhydroxymethylphosphonic acids as inhibitors of CD45.

J. Siekierka, J. Davis, D. Cavender, 1997, Bioorganic & medicinal chemistry.

6-Amino-2-(4-fluorophenyl)-4-methoxy-3- (4-pyridyl)-1H-pyrrolo[2, 3-b]pyridine (RWJ 68354): a potent and selective p38 kinase inhibitor.

J. Siekierka, J. Davis, P. Schafer, 1998, Journal of medicinal chemistry.

Substituted dipiperidine alcohols as potent CCR2 antagonists.

M. Singer, Scott R Pollack, D. Cavender, 2008, Bioorganic & medicinal chemistry letters.

Imidazopyrimidines, potent inhibitors of p38 MAP kinase.

J. Siekierka, J. Dodd, J. Henry, 2003, Bioorganic & medicinal chemistry letters.

Simplified staurosporine analogs as potent JAK3 inhibitors.

Xin Chen, Xin Chen, L. Wilson, 2007, Bioorganic & medicinal chemistry letters.

Potent inhibitors of the MAP kinase p38.

J. Siekierka, P. Schafer, I. Turchi, 1998, Bioorganic & medicinal chemistry letters.

Melanocortin-5 receptor and sebogenesis.

A. Pappas, Wen-Hwa Li, M. Eisinger, 2011, European journal of pharmacology.

PREGNANCY OUTCOME IN DIABETICS WITH OTHER ENDOCRINE DISORDERS

D. Wagener, K. Cruickshanks, R. Laporte, 1984, The Lancet.

The Pittsburgh Insulin-dependent Diabetes Mellitus (IDDM) Morbidity and Mortality Study: Mortality Results

L. Kuller, D. Wagener, K. Cruickshanks, 1984, Diabetes.

Nonhuman primate responses to murine and humanized OKT4A.

F. Delmonico, T. Kawai, A. Cosimi, 1993, Transplantation.

Modulation of cell-mediated immunity in mice with chronic unisexual or bisexual Schistosoma mansoni cercarial infection.

M. Diab, D. Cavender, G. Higashi, 1989, Annals of tropical medicine and parasitology.

Synthetic staurosporines via a ring closing metathesis strategy as potent JAK3 inhibitors and modulators of allergic responses.

Xin Chen, Xin Chen, L. Wilson, 2009, Bioorganic & medicinal chemistry letters.

p38 MAP Kinase Inhibition Reduces Propionibacterium acnes-Induced Inflammation in Vitro

M. Southall, Wen-Hwa Li, D. Cavender, 2015, Dermatology and Therapy.

The Pittsburgh Insulin-Dependent Diabetes Mellitus (IDDM) study. HLA antigens and haplotypes as risk factors for the development of IDDM in IDDM patients and their siblings.

L. Kuller, D. Wagener, M. Eberhardt, 1984, Journal of chronic diseases.

RWJ 67657, a potent, orally active inhibitor of p38 mitogen-activated protein kinase.

J. Siekierka, J. Davis, P. Schafer, 1999, The Journal of pharmacology and experimental therapeutics.

Separation and characterization of human T lymphocytes with varying adhesiveness for endothelial cells.

D. Haskard, M. Ziff, D. Cavender, 1988, Cellular immunology.

Effects of bacterial lipopolysaccharide on the binding of lymphocytes to endothelial cell monolayers.

C. Yu, D. Haskard, M. Ziff, 1986, Journal of immunology.

Lymphocyte adhesion to endothelial cells in vitro: models for the study of normal lymphocyte recirculation and lymphocyte emigration into chronic inflammatory lesions.

D. Cavender, 1989, The Journal of investigative dermatology.

Targeting cytosolic phospholipase A2 by arachidonyl trifluoromethyl ketone prevents chronic inflammation in mice.

R. Malaviya, D. Cavender, R. Sur, 2006, European journal of pharmacology.

In Vivo Activity of a Phospholipase C Inhibitor, 1-(6-((17β-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione (U73122), in Acute and Chronic Inflammatory Reactions

T. Kirchner, M. Singer, D. Cavender, 2004, Journal of Pharmacology and Experimental Therapeutics.

IL-11, IL-1α, IL-6, and TNF-α are induced by solar radiation in vitro and may be involved in facial subcutaneous fat loss in vivo.

A. Pappas, Wen-Hwa Li, E. Ruvolo, 2013, Journal of dermatological science.

COXSACKIE INFECTION AND DIABETES

L. Kuller, R. Laporte, B. Rabin, 1983, The Lancet.

Pathogenetic factors in rheumatoid synovitis.

D. Haskard, M. Ziff, D. Cavender, 1988, British journal of rheumatology.

Inhibitors of unactivated p38 MAP kinase.

Thomas M. Razler, M. Reuman, Xun Li, 2006, Bioorganic & medicinal chemistry letters.

Pathways to chronic inflammation in rheumatoid synovitis.

N. Oppenheimer-Marks, P. Miossec, D. Haskard, 1987, Federation proceedings.

Interferon-gamma increases susceptibility of murine pancreatic beta cells to lysis by allogeneic cytotoxic T lymphocytes.

D. Cavender, P. Wood, J. Cearns-Spielman, 1990, Autoimmunity.

Absence of Antienterobacteriaceae and anti-HLA-B27 antibodies in mitogen stimulated cultures of lymphocytes from patients with Reiter's syndrome and ankylosing spondylitis.

M. Ziff, D. Cavender, Cavender De, 1988, The Journal of rheumatology.

Role of Janus kinase-2 in IgE receptor-mediated leukotriene C4 production by mast cells.

R. Malaviya, D. Cavender, R. Sur, 2009, Biochemical and biophysical research communications.

Analyses on possible heterogeneity of IDDM based on presence of islet cell cytoplasmic antibody at diagnosis.

D. Wagener, M. Eberhardt, B. Rabin, 1989, Autoimmunity.