Kien Trân

发表

Size-Reduced Macrocyclic Analogues of [Pyr1]-apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac Effects.

O. Lesur, M. Bouvier, P. Sarret, 2022, Journal of medicinal chemistry.

A Systematic Exploration of Macrocyclization in Apelin-13: Impact on Binding, Signaling, Stability, and Cardiovascular Effects.

O. Lesur, D. Salvail, R. Dumaine, 2018, Journal of medicinal chemistry.

Novel Insights into the Mode of Action of Vasorelaxant Synthetic Polyoxygenated Chalcones

S. Faure, Kien Trân, J. Helesbeux, 2020, International journal of molecular sciences.

Apelin Stimulation of the Perivascular MuSC Niche Enhances Endogenous Repair in Muscular Dystrophy

Michelle S. Scott, Nicolas A. Dumont, F. Balg, 2022, bioRxiv.

Structure-Activity Relationship and Bioactivity of Short Analogues of ELABELA as Agonists of the Apelin Receptor.

O. Lesur, M. Bouvier, P. Sarret, 2020, Journal of medicinal chemistry.

Apelin improves angiogenesis and blood flow reperfusion following lower limb ischemia in diabetic mice

P. Geraldes, É. Marsault, M. Auger-Messier, 2023, bioRxiv.

Surface activity of a fluorinated carbohydrate ester in water/carbon dioxide emulsions.

C. Jérôme, F. Boury, B. Calvignac, 2013, Journal of colloid and interface science.

Constraining the Side Chain of C-Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile.

O. Lesur, M. Bouvier, P. Sarret, 2021, Journal of medicinal chemistry.

Elabela Protects Spontaneously Hypertensive Rats From Hypertension and Cardiorenal Dysfunctions Exacerbated by Dietary High-Salt Intake

O. Lesur, A. Carpentier, C. Noll, 2021, Frontiers in Pharmacology.

Apelins, ELABELA, and their derivatives: Peptidic regulators of the cardiovascular system and beyond

O. Lesur, P. Lavigne, P. Sarret, 2019 .

Signaling Modulation via Minimal C-Terminal Modifications of Apelin-13.

P. Sarret, Jean-Michel Longpré, É. Marsault, 2023, ACS pharmacology & translational science.

Apelin-13 in septic shock: effective in supporting hemodynamics in sheep but compromised by enzymatic breakdown in patients

O. Lesur, J. Praud, J. Lamoureux, 2021, Scientific Reports.

Apelins, ELABELA, and their derivatives: Peptidic regulators of the cardiovascular system and beyond

O. Lesur, P. Lavigne, P. Sarret, 2019 .

Design, Synthesis, Pharmacological Evaluation and Vascular Effects of Delphinidin Analogues.

S. Faure, C. Lugnier, Kien Trân, 2019, Current pharmaceutical design.

Apelin prevents diabetes-induced poor collateral vessel formation and blood flow reperfusion in ischemic limb

P. Geraldes, É. Marsault, M. Auger-Messier, 2023, Frontiers in Cardiovascular Medicine.