Dingyi Wen

发表

N-terminally PEGylated human interferon-beta-1a with improved pharmacokinetic properties and in vivo efficacy in a melanoma angiogenesis model.

A. Whitty, D. Baker, D. Lindner, 2006, Bioconjugate chemistry.

Expression of Sonic hedgehog-Fc fusion protein in Pichia pastoris. Identification and control of post-translational, chemical, and proteolytic modifications.

A. Gill, A. Galdes, F. Taylor, 2003, Protein expression and purification.

Long-acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model.

T. Engber, R. Pepinsky, D. Lepage, 2002, Journal of pharmaceutical sciences.

EFab domain substitution as a solution to the light-chain pairing problem of bispecific antibodies

H. Cooke, J. Arndt, M. Preyer, 2018, mAbs.

The crystal structure of the catalytic domain of tau tubulin kinase 2 in complex with a small-molecule inhibitor.

Kerri A Spilker, D. Marcotte, J. Chodaparambil, 2020, Acta crystallographica. Section F, Structural biology communications.

An antibody-cytotoxic conjugate, BIIB015, is a new targeted therapy for Cripto positive tumours.

M. Sanicola, V. Bailly, Yaping Sun, 2011, European journal of cancer.

Growth Factor Induction of Cripto-1 Shedding by Glycosylphosphatidylinositol-Phospholipase D and Enhancement of Endothelial Cell Migration*

C. Bianco, L. Strizzi, M. Mancino, 2007, Journal of Biological Chemistry.

Design, synthesis, and structure-activity relationships of haloenol lactones: site-directed and isozyme-selective glutathione S-transferase inhibitors.

Kaixian Chen, Hualiang Jiang, P. Zimniak, 2004, Journal of medicinal chemistry.

The CRIPTO/FRL-1/CRYPTIC (CFC) domain of human Cripto. Functional and structural insights through disulfide structure analysis.

H. V. van Vlijmen, Juswinder Singh, H. Adkins, 2003, European journal of biochemistry.

Disulfide structure of the leucine-rich repeat C-terminal cap and C-terminal stalk region of Nogo-66 receptor.

L. Silvian, C. Wildes, S. Mi, 2005, Biochemistry.

Identification and sequencing of N-terminal peptides in proteins by LC-Fluorescence-MS/MS: an approach to replacement of the Edman degradation.

Yongsheng Xiao, Malgorzata M Vecchi, Dingyi Wen, 2019, Analytical chemistry.

Structure-Function Relationships in an Antifreeze Polypeptide

Dingyi Wen, Richard A. LaursenS, 1993 .

Selectivity of BAFF/BLyS and APRIL for binding to the TNF family receptors BAFFR/BR3 and BCMA.

Yen-Ming Hsu, Fang Qian, Adrian Whitty, 2005, Biochemistry.

Control of misincorporation of serine for asparagine during antibody production using CHO cells

Paul Chen, Yao-ming Huang, T. Ryll, 2010, Biotechnology and bioengineering.

Discovery and Investigation of Misincorporation of Serine at Asparagine Positions in Recombinant Proteins Expressed in Chinese Hamster Ovary Cells

Yao-ming Huang, N. Pederson, E. Garber, 2009, The Journal of Biological Chemistry.

A Prodomain Fragment from the Proteolytic Activation of Growth Differentiation Factor 11 Remains Associated with the Mature Growth Factor and Keeps It Soluble.

T. Walz, A. Lehmann, N. Pederson, 2017, Biochemistry.

Identification of a Palmitic Acid-modified Form of Human Sonic hedgehog*

C. Ambrose, D. Baker, S. Bixler, 1998, The Journal of Biological Chemistry.

Picomole-level mapping of protein disulfides by mass spectrometry following partial reduction and alkylation.

T. Zheng, Yaping Sun, Dingyi Wen, 2008, Analytical biochemistry.

Determination of the Disulfide Structure of Murine Meteorin, a Neurotrophic Factor, by LC-MS and Electron Transfer Dissociation-High-Energy Collisional Dissociation Analysis of Proteolytic Fragments.

R. Pepinsky, B. Gong, Yongsheng Xiao, 2017, Analytical chemistry.

Engineering potent long-acting variants of the Wnt inhibitor DKK2

Richelle Sopko, A. Lehmann, N. Pederson, 2017, Protein engineering, design & selection : PEDS.

Expression, purification, and characterization of rat interferon-beta, and preparation of an N-terminally PEGylated form with improved pharmacokinetic parameters.

B. Domon, D. Baker, R. Arduini, 2004, Protein expression and purification.

Efficient on-column conversion of IgG1 trisulfide linkages to native disulfides in tandem with Protein A affinity chromatography.

Li Zang, R. Pepinsky, David R H Evans, 2010, Journal of chromatography. A.

Characterization of trisulfide modification in antibodies.

Rashmi Kshirsagar, Werner Meier, P. Weinreb, 2010, Analytical biochemistry.

Resolution of disulfide heterogeneity in Nogo receptor 1 fusion proteins by molecular engineering

J. Relton, P. Weinreb, L. Silvian, 2010, Biotechnology and applied biochemistry.

Distinguishing between Leucine and Isoleucine by Integrated LC-MS Analysis Using an Orbitrap Fusion Mass Spectrometer.

Yongsheng Xiao, Dingyi Wen, Yongsheng Xiao, 2016, Analytical chemistry.

Production of a PEGylated Fab' of the anti-LINGO-1 Li33 antibody and assessment of its biochemical and functional properties in vitro and in a rat model of remyelination.

S. Mi, X. Lee, E. Garber, 2011, Bioconjugate chemistry.

Discovery and investigation of O-xylosylation in engineered proteins containing a (GGGGS)n linker.

W. Meier, Dingyi Wen, X. Hronowski, 2013, Analytical chemistry.

Enhanced potency of human Sonic hedgehog by hydrophobic modification.

A. Whitty, P. Weinreb, D. Baker, 2001, Biochemistry.