Elsa Wagner-Rousset

发表

Insights from native mass spectrometry approaches for top- and middle- level characterization of site-specific antibody-drug conjugates

S. Cianférani, A. Beck, P. Drake, 2017, mAbs.

Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates

François Debaene, S. Cianférani, J. Marcoux, 2016, Expert review of proteomics.

Correct primary structure assessment and extensive glyco-profiling of cetuximab by a combination of intact, middle-up, middle-down and bottom-up ESI and MALDI mass spectrometry techniques

D. Suckau, C. Baessmann, A. Beck, 2013, mAbs.

Extending mass spectrometry contribution to therapeutic monoclonal antibody lead optimization: characterization of immune complexes using noncovalent ESI-MS.

S. Sanglier-Cianférani, A. van Dorsselaer, A. Robert, 2009, Analytical chemistry.

NanoLC Chips MS/MS for the characterization of N-glycopeptides generated from trypsin digestion of a monoclonal antibody.

A. van Dorsselaer, A. Beck, Christine Schaeffer‐Reiss, 2013, Methods in molecular biology.

Development of a fast workflow to screen the charge variants of therapeutic antibodies.

D. Guillarme, S. Cianférani, A. Beck, 2017, Journal of chromatography. A.

Characterization of the N-terminal heterogeneities of monoclonal antibodies using in-gel charge derivatization of α-amines and LC-MS/MS.

S. Cianférani, A. van Dorsselaer, A. Beck, 2015, Analytical chemistry.

Antibody Glycans Characterization

A. Beck, A. Dorsselaer, Elsa Wagner-Rousset, 2010 .

Trends in glycosylation, glycoanalysis and glycoengineering of therapeutic antibodies and Fc-fusion proteins.

T. Wurch, A. van Dorsselaer, A. Beck, 2008, Current pharmaceutical biotechnology.

Time resolved native ion-mobility mass spectrometry to monitor dynamics of IgG4 Fab arm exchange and "bispecific" monoclonal antibody formation.

François Debaene, S. Cianférani, A. van Dorsselaer, 2013, Analytical chemistry.

1 Monoclonal Antibody N-Glycosylation Profiling using 1 Capillary Electrophoresis – Mass Spectrometry : 2 Assessment and Method Validation . 3

D. Guillarme, V. D’Atri, A. Beck, 2019 .

Drug Loading and Distribution of ADCs After Reduction or IdeS Digestion and Reduction.

D. Guillarme, Yannis-Nicolas François, S. Cianférani, 2020, Methods in molecular biology.

Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine‐linked antibody drug conjugate

S. Cianférani, A. van Dorsselaer, J. Marcoux, 2015, Protein science : a publication of the Protein Society.

High-Resolution IMS-MS to Assign Additional Disulfide Bridge Pairing in Complementarity-Determining Regions of an IgG4 Monoclonal Antibody.

S. Cianférani, A. Beck, K. Giles, 2021, Journal of the American Society for Mass Spectrometry.

Cutting-edge mass spectrometry characterization of originator, biosimilar and biobetter antibodies.

Alain Van Dorsselaer, Alain Beck, François Debaene, 2015, Journal of mass spectrometry : JMS.

Characterization of therapeutic antibodies and related products.

Alain Van Dorsselaer, Alain Beck, A. van Dorsselaer, 2013, Analytical chemistry.

Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody.

Alain Beck, R. Ionescu, A. Beck, 2009, Analytical biochemistry.

Epitope characterization of anti-JAM-A antibodies using orthogonal mass spectrometry and surface plasmon resonance approaches

François Debaene, S. Cianférani, A. Beck, 2017, mAbs.

Monoclonal antibody N-glycosylation profiling using capillary electrophoresis - Mass spectrometry: Assessment and method validation.

Davy Guillarme, Alain Beck, Yannis-Nicolas François, 2018, Talanta.

Antibody-drug conjugate model fast characterization by LC-MS following IdeS proteolytic digestion

Alain Beck, A. Beck, Daniel Ayoub, 2013, mAbs.

Protocols for the analytical characterization of therapeutic monoclonal antibodies. I - Non-denaturing chromatographic techniques.

D. Guillarme, Balázs Bobály, V. D’Atri, 2017, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Analytical characterization of biosimilar antibodies and Fc-fusion proteins

François Debaene, C. Carapito, A. Beck, 2013 .

Native Mass Spectrometry, Ion Mobility, and Collision-Induced Unfolding for Conformational Characterization of IgG4 Monoclonal Antibodies.

S. Cianférani, A. Beck, O. Hernandez-Alba, 2018, Analytical chemistry.

Innovative native MS methodologies for antibody drug conjugate characterization: High resolution native MS and IM-MS for average DAR and DAR distribution assessment.

Alain Van Dorsselaer, Alain Beck, François Debaene, 2014, Analytical chemistry.

Mass Spectrometry‐Based Strategies for Therapeutic Antibodies Extensive Characterization and Optimization (OptimAbs)

François Debaene, S. Cianférani, A. Beck, 2020 .

Middle level IM-MS and CIU experiments for improved therapeutic immunoglobulin subclass fingerprinting.

S. Cianférani, A. Beck, Thomas Botzanowski, 2020, Analytical chemistry.

Middle-level IM-MS and CIU experiments for improved therapeutic immunoglobulin isotype fingerprinting

S. Cianférani, A. Beck, Thomas Botzanowski, 2020, bioRxiv.

Fast Afucosylation Profiling of Glycoengineered Antibody Subunits by Middle-Up Mass Spectrometry.

D. Guillarme, Yannis-Nicolas François, S. Cianférani, 2021, Methods in molecular biology.

Antibody-drug conjugate model fast characterization by LC-MS following IdeS proteolytic digestion.

A. Beck, Daniel Ayoub, N. Corvaïa, 2014, mAbs.

Structural Characterization of Antibodies by Mass Spectrometry

J. Strub, A. Beck, A. Dorsselaer, 2010 .

The way forward, enhanced characterization of therapeutic antibody glycosylation: comparison of three level mass spectrometry-based strategies.

Alain Van Dorsselaer, Alain Beck, Christine Schaeffer, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates

François Debaene, S. Cianférani, A. Beck, 2016, Expert review of proteomics.

Extending mass spectrometry contribution to therapeutic monoclonal antibody lead optimization: characterization of immune complexes using noncovalent ESI-MS.

A. van Dorsselaer, A. Robert, A. Beck, 2009, Analytical chemistry.

Noncovalent mass spectrometry for the characterization of antibody/antigen complexes.

A. van Dorsselaer, A. Beck, N. Corvaïa, 2013, Methods in molecular biology.