K. Mewes

发表

Determining the Depth of Injury in Bioengineered Tissue Models of Cornea and Conjunctiva for the Prediction of All Three Ocular GHS Categories

J. Brandner, P. Houdek, I. Moll, 2014, PloS one.

Expansion of the Cosmetics Europe skin sensitisation database with new substances and PPRA data.

S. Hoffmann, E. van Vliet, N. Alépée, 2022, Regulatory toxicology and pharmacology : RTP.

Short communication In vitro eye irritation testing using the open source reconstructed hemicornea – a ring trial 1

J. Brandner, D. Petersohn, M. Engelke, 2017 .

In vitro eye irritation testing using the open source reconstructed hemicornea - a ring trial.

J. Brandner, D. Petersohn, M. Engelke, 2017, ALTEX.

Development of a next generation risk assessment framework for the evaluation of skin sensitisation of cosmetic ingredients.

Martina Klaric, Sebastian Hoffmann, Petra S Kern, 2020, Regulatory toxicology and pharmacology : RTP.

Evaluation of beneficial and adverse effects of glucocorticoids on a newly developed full-thickness skin model.

J. Bereiter-Hahn, M. Spiegel, R. Kaufmann, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Cosmetics Europe compilation of historical serious eye damage/eye irritation in vivo data analysed by drivers of classification to support the selection of chemicals for development and evaluation of alternative methods/strategies: the Draize eye test Reference Database (DRD)

João Barroso, Martina Klaric, Nathalie Alépée, 2016, Archives of Toxicology.

Development of a defined approach for eye irritation or serious eye damage for neat liquids based on cosmetics Europe analysis of in vitro RhCE and BCOP test methods.

N. Alépée, U. Pfannenbecker, E. Adriaens, 2019, Toxicology in vitro : an international journal published in association with BIBRA.

Development of a defined approach for eye irritation or serious eye damage for liquids, neat and in dilution, based on cosmetics Europe analysis of in vitro STE and BCOP test methods.

N. Alépée, U. Pfannenbecker, E. Adriaens, 2019, Toxicology in vitro : an international journal published in association with BIBRA.

Assessment of cosmetic ingredients in the in vitro reconstructed human epidermis test method EpiSkin™ using HPLC/UPLC-spectrophotometry in the MTT-reduction assay.

N. Alépée, U. Pfannenbecker, M. Klarić, 2016, Toxicology in vitro : an international journal published in association with BIBRA.

A human hemi-cornea model for eye irritation testing: quality control of production, reliability and predictive capacity.

K R Mewes, B. Rusche, D. Gabel, 2013, Toxicology in vitro : an international journal published in association with BIBRA.

The importance of understanding drivers of irritation in vivo for selection of chemicals used in the development and evaluation of in vitro eye irritation assays: Cosmetics Europe analysis

A. D. Smedt, N. Alépée, B. Wever, 2013 .

Non-animal methods to predict skin sensitization (II): an assessment of defined approaches**

Bertrand Desprez, Martina Klaric, David Allen, 2018, Critical reviews in toxicology.

Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database*

Bertrand Desprez, Martina Klaric, David Allen, 2018, Critical reviews in toxicology.

The Phenion® Full-Thickness Skin Model for Percutaneous Absorption Testing

M. Schäfer-Korting, M. Schäfer-Korting, K. Ackermann, 2009, Skin Pharmacology and Physiology.

Catch-up validation study of an in vitro skin irritation test method based on an open source reconstructed epidermis (phase II).

S. Hoffmann, H. Walles, L. Schober, 2016, Toxicology in vitro : an international journal published in association with BIBRA.

Elastin Expression in a Newly Developed Full-Thickness Skin Equivalent

A. Bernd, K. Mewes, M. Raus, 2006, Skin Pharmacology and Physiology.

The importance of being three-dimensional in biology

D. Petersohn, T. Förster, K. Mewes, 2019 .

Reconstructed 3 D Tissues for Efficacy and Safety Testing of Cosmetic Ingredients

K. Reisinger, T. Förster, K. Mewes, 2018 .

Extending the applicability domain of the human cell line activation test (h-CLAT).

D. Petersohn, K. Mewes, U. Engels, 2020, ALTEX.

Performance Statistics of Defined Approaches for Eye Hazard Identification of Non-Surfactant Liquids to Distinguish Between the Three United Nations Globally Harmonized System Categories

N. Alépée, E. Adriaens, D. Bagley, 2021, Applied In Vitro Toxicology.

Catch-up validation study of an in vitro skin irritation test method based on an open source reconstructed epidermis (phase I).

M Liebsch, K R Mewes, A Fischer, 2016, Toxicology in vitro : an international journal published in association with BIBRA.

Development of a defined approach for eye hazard identification of chemicals having surfactant properties according to the three UN GHS categories.

N. Alépée, E. Adriaens, J. Magby, 2023, Toxicology in vitro : an international journal published in association with BIBRA.

P17-23 Innovative defined approaches for non-surfactant liquids for eye hazard assessment based on physicochemical properties and OECD-approved test methods

N. Alépée, E. Adriaens, D. Bagley, 2022, Toxicology Letters.

Overall performance of Bovine Corneal Opacity and Permeability (BCOP) Laser Light-Based Opacitometer (LLBO) test method with regard to solid and liquid chemicals testing.

N. Alépée, U. Pfannenbecker, E. Adriaens, 2020, Toxicology in Vitro.

Use of HPLC/UPLC-spectrophotometry for detection of formazan in in vitro Reconstructed human Tissue (RhT)-based test methods employing the MTT-reduction assay to expand their applicability to strongly coloured test chemicals.

A. De Smedt, B. De Wever, N. Alépée, 2015, Toxicology in vitro : an international journal published in association with BIBRA.