Karin A Vallega

发表

MET inhibition downregulates DR4 expression in MET-amplified lung cancer cells with acquired resistance to EGFR inhibitors through suppressing AP-1-mediated transcription

Liang Deng, Shuo Zhang, Shi-Yong Sun, 2021, Neoplasia.

Overcoming acquired resistance to third-generation EGFR inhibitors by targeting activation of intrinsic apoptotic pathway through Mcl-1 inhibition, Bax activation, or both

T. Owonikoko, S. Ramalingam, Shi-Yong Sun, 2022, Oncogene.

Macrophage-Conditioned Media Promotes Adipocyte Cancer Association, Which in Turn Stimulates Breast Cancer Proliferation and Migration

Q. Sang, D. Bosco, Yi Ren, 2020, Biomolecules.

Managing Acquired Resistance to Third-Generation EGFR Tyrosine Kinase Inhibitors Through Co-Targeting MEK/ERK Signaling

Shi-Yong Sun, Karin A Vallega, Danlei Yu, 2021, Lung Cancer.

The novel BET degrader, QCA570, is highly active against the growth of human NSCLC cells and synergizes with osimertinib in suppressing osimertinib-resistant EGFR-mutant NSCLC cells.

Shaomeng Wang, Shi-Yong Sun, Luxiao Chen, 2022, American journal of cancer research.

Therapeutic potential of the novel Bcl‐2/Bcl‐XL dual inhibitor, APG1252, alone or in combination against non‐small cell lung cancer

Shi-Yong Sun, Y. Zhai, Dongsheng Wang, 2022, Molecular carcinogenesis.

The natural product berberine synergizes with osimertinib preferentially against MET-amplified osimertinib-resistant lung cancer via direct MET inhibition.

S. Ramalingam, Shi-Yong Sun, Haiying Chen, 2021, Pharmacological research.

Membrane-Associated RING-CH 8 Functions as a Novel PD-L1 E3 Ligase to Mediate PD-L1 Degradation Induced by EGFR Inhibitors

G. Qian, T. Owonikoko, S. Ramalingam, 2021, Molecular Cancer Research.

Therapeutic efficacy of the novel SHP2 degrader SHP2-D26, alone or in combination, against lung cancer is associated with modulation of p70S6K/S6, Bim and Mcl-1

Shaomeng Wang, S. Ramalingam, Shi-Yong Sun, 2022, Cancer Gene Therapy.

Does the natural product, honokiol, have value in the battle against osimertinib resistance?

Shi-Yong Sun, Karin A Vallega, 2020, Oncoscience.

Elevated Resistin Gene Expression in African American Estrogen and Progesterone Receptor Negative Breast Cancer

Kaixian Yu, Q. Sang, Karin A Vallega, 2016, PloS one.

Proteomic characterization of paired non-malignant and malignant African-American prostate epithelial cell lines distinguishes them by structural proteins

Kaixian Yu, Q. Sang, C. Yates, 2017, BMC Cancer.