Jing Shi

发表

Design, Synthesis and Biological Evaluation of Cinnamic Acyl Shikonin Derivatives

Yong-Hua Yang, Hongyan Lin, J. Qi, 2013, Chemical biology & drug design.

Synthesis, molecular modeling and biological evaluation of N-benzylidene-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetohydrazide derivatives as potential anticancer agents.

Hai‐Liang Zhu, Yu-Shun Yang, Yong Yin, 2014, Bioorganic & medicinal chemistry.

Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism studies.

Meng Lei, Yongqiang Zhu, Jing Shi, 2018, Bioorganic & medicinal chemistry.

Design, synthesis, and biological activity evaluation of a series of novel sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia.

Wen-long Huang, Hai Qian, W. Shi, 2021, Bioorganic chemistry.

Design and synthesis of fluoroacylshikonin as an anticancer agent.

Yong-Hua Yang, J. Qi, S. Baloch, 2013, Chirality.

Preparation and biological evaluation of soluble tetrapeptide epoxyketone proteasome inhibitors.

Jian Shen, Meng Lei, Xiaoqing Du, 2019, Bioorganic & medicinal chemistry.

Design, synthesis, SAR discussion, in vitro and in vivo evaluation of novel selective EGFR modulator to inhibit L858R/T790M double mutants.

Meng Lei, Yongqiang Zhu, Hao Cheng, 2017, European journal of medicinal chemistry.

3D-QSAR-aided design, synthesis, in vitro and in vivo evaluation of dipeptidyl boronic acid proteasome inhibitors and mechanism studies.

Hailing Li, Meng Lei, Yongqiang Zhu, 2016, Bioorganic & medicinal chemistry.

1,3,4-Oxadiazole derivatives as potential antitumor agents: discovery, optimization and biological activity valuation

Yin Luo, Jing Shi, Zhi-Jun Liu, 2016 .

Design, synthesis and docking studies of novel dipeptidyl boronic acid proteasome inhibitors constructed from αα- and αβ-amino acids.

Cheng Jiang, Meng Lei, Yongqiang Zhu, 2016, Bioorganic & medicinal chemistry letters.

Design, synthesis and mechanism of novel shikonin derivatives as potent anticancer agents

Yu Zhu, Yong-Hua Yang, G. Lu, 2015 .

Synthesis and the hepatoprotective activity of dibenzocyclooctadiene lignan derivatives.

Xiao-jiang Hao, Lie-jun Huang, Jing Shi, 2014, Bioorganic & medicinal chemistry letters.

Co-delivery of paclitaxel and gemcitabine via a self-assembling nanoparticle for targeted treatment of breast cancer

Meng Lei, Xiaoqing Du, Yongqiang Zhu, 2019, RSC advances.

Design, Synthesis and Biological Evaluation of the Quinazoline Derivatives as L858R/T790M/C797S Triple Mutant Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors.

Shifa Wang, Mingxin Li, Yongqiang Zhu, 2020, Chemical & pharmaceutical bulletin.

KPT‐330 and Y219 exert a synergistic antitumor effect in triple‐negative breast cancer through inhibiting NF‐κB signaling

Meng Lei, Jing Shi, Jia Wang, 2023, FEBS open bio.

Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism studies.

Meng Lei, Yongqiang Zhu, Jing Shi, 2018, Bioorganic & medicinal chemistry.