N. Zyk

发表

Design, synthesis and biological evaluation of novel potent MDM2/p53 small-molecule inhibitors.

A. Tonevitsky, O. Dontsova, Y. Ivanenkov, 2015, Bioorganic & medicinal chemistry letters.

Modern Trends of Organic Chemistry in Russian Universities

R. S. Begunov, A. V. Kolobov, K. I. Kobrakov, 2018, Russian Journal of Organic Chemistry.

Synthesis and organogelating behaviour of urea- and Fmoc-containing diphenylalanine based hexaamide

G. Bondarenko, A. Majouga, V. Dolzhikova, 2021 .

PSMA-targeted small-molecule docetaxel conjugate: Synthesis and preclinical evaluation.

V. Pokrovsky, Y. Ivanenkov, A. Majouga, 2021, European journal of medicinal chemistry.

Pt(IV) Prodrugs with Non-Steroidal Anti-inflammatory Drugs in the Axial Position.

V. N. Nikitina, D. Sakharov, A. Garanina, 2022, Journal of medicinal chemistry.

Novel DNA fluorescence probes based on 2-thioxo-tetrahydro-4H-imidazol-4-ones: synthetic and biological studies

O. Dontsova, N. S. Zefirov, A. Majouga, 2012 .

Synthesis of 1,3-diaryl-spiro[azetidine-2,3′-indoline]-2′,4-diones via the Staudinger reaction: cis- or trans-diastereoselectivity with different addition modes

A. Majouga, D. Skvortsov, V. Tafeenko, 2020, RSC advances.

Reaction of arylboronic acids with 5-aryl-3-substituted-2-thioxoimidazolin-4-ones

V. Koteliansky, Y. Ivanenkov, A. Majouga, 2016 .

New separation materials based on gold nanoparticles

O. Shpigun, A. Majouga, N. Kuz'menko, 2010 .

Synthesis and biological activity of 5-aryliden-2-thiohydantoin S-aryl derivatives.

D. Laikov, Y. Ivanenkov, V. Aladinskiy, 2020, Bioorganic chemistry.

New copper(II) thiohydantoin complexes: Synthesis, characterization, and assessment of their interaction with bovine serum albumin and DNA.

M. Proskurnin, Y. Ivanenkov, V. Aladinskiy, 2017, Journal of inorganic biochemistry.

Cleavage of the C-S bond with the formation of a binuclear copper complex with 2-thiolato-3-phenyl-5-(pyridine-2-ylmethylene)-3,5-dihydro-4H-imidazole-4-one. A new mimic of the active site of N2O reductase.

A. Majouga, A. Khlobystov, M. Lebedeva, 2013, Dalton transactions.

Lithium Perchlorate as a Reagent for Synthesis of Covalently Bonded Organic Perchlorates via Electrophilic Additions of Halogens and Nitronium Tetrafluoroborate to Olefins

N. Zefirov, V. Zhdankin, N. Zyk, 1982 .

The first example of Cu(I) complex with 5-pyrazolyl-2-thioxotetrahydro-4H-imidazol-4-one: Synthesis and structural characterization

A. Majouga, A. Moiseeva, E. Beloglazkina, 2016 .

Copper coordination compounds with (5Z,5Z′)-2,2′-(alkane-α,ω-diyldiselenyl)-bis-5-(2-pyridylmethylene)-3,5-dihydro-4H-imidazol-4-ones. Comparison with sulfur analogue

R. Borisov, A. Majouga, V. Pergushov, 2022, RSC advances.

Synthesis, isomerization and biological activity of novel 2-selenohydantoin derivatives.

M. V. Polyakova, V. Koteliansky, Y. Ivanenkov, 2016, Bioorganic & medicinal chemistry.

Binuclear copper(II) complex with 2-imidazolylbenzothiazole and bridged chloride ligands

A. Moiseeva, E. Beloglazkina, E. S. Barskaya, 2019, Mendeleev Communications.

Mixed valence copper(I,II) binuclear complexes with unexpected structure: synthesis, biological properties and anticancer activity.

O. Dontsova, N. S. Zefirov, A. Kabanov, 2014, Journal of medicinal chemistry.

Oxidative dehydrogenation of 5-(pyridine-2-yl-methyl)-2-thioxo-4-imidazolidinones in complexation reaction with copper(II) chloride

A. Majouga, E. Beloglazkina, A. Mironov, 2015 .

NOVEL COPPER-CONTAINING CYTOTOXIC AGENTS BASED ON 2-THIOXOIMIDAZOLONES.

V. N. Nikitina, A. Naumov, D. Sakharov, 2020, Journal of medicinal chemistry.

An Improved Protocol for Synthesis of 3‐Substituted 5‐Arylidene‐2‐thiohydantoins: Two‐step Procedure Alternative to Classical Methods

V. Koteliansky, A. Majouga, E. Beloglazkina, 2016 .

First organic-inorganic hybrid material based on AgNO3 and 3-pyridine containing 2-thiohydantoin

A. Majouga, E. Beloglazkina, S. Vatsadze, 2007 .

New stereoselective intramolecular redox reaction in the system of 3,7-diazabicyclo[3.3.1]nonan-9-one

A. Churakov, S. Vatsadze, V. Tyurin, 2006 .

4,5-dihydroisoxazoles from arylcyclopropanes: II. Reaction of arylcyclopropanes with nitrosyl chloride activated by sulfur(VI) oxide

A. Gavrilova, O. B. Bondarenko, N. Zyk, 2007 .

Bis[4-(methylthio)phenylmethyleneaminophenyl] disulfide, 2-[4-(methylthio)phenyl]-2,3-dihydro-1,3-benzothiazole, and its nickel(II) and cobalt(II) complexes: Synthesis, adsorption on gold surface and electrochemical characterization

I. V. Yudin, A. Majouga, E. Beloglazkina, 2007 .

cis-Diastereoselective Synthesis of Spirooxindolo-β-Lactams by Staudinger Cycloaddition with TsCl as Activating Co-reagent

E. Beloglazkina, V. Tafeenko, N. Zyk, 2021, ACS omega.

1,7-Dimethyl-1,7-dichloromethyl-5,8-ethenodecalin-3-ene-2,6-dione. Structure, bromination, electrochemistry

A. Churakov, A. Moiseeva, E. Beloglazkina, 2012, Russian Journal of General Chemistry.

Synthesis of Enantiomerically Pure Thioureas and Thiohydantoins Based on (R)- and (S)-1-(2,4-Dimethoxy-phenyl)ethan-1-amines

V. Tafeenko, E. Beloglazkina, N. Zyk, 2022, Russian Journal of Organic Chemistry.

Synthesis and electrochemical study of complexes of 2-methylthio-5-(pyridylmethylidene)-3,5-dihydro-4H-imidazol-4-ones with transition metals (Co, Ni, and Cu). Molecular structures of CuIIL1Cl2 (L1 is (5Z)-2-methylthio-3-phenyl-5-(α-pyridylmethylidene)-3,5-dihydro-4H-imidazol-4-one) and CoIIL2Cl2 (L

A. Majouga, K. Butin, A. Moiseeva, 2005 .

Thiourea Modified Doxorubicin: A Perspective pH-Sensitive Prodrug.

O. Fedorova, A. Majouga, G. Jonusauskas, 2019, Bioconjugate chemistry.

Novel 2-aminoimidazole-4-one complexes of copper(II) and cobalt(II): Synthesis, structural characterization and cytotoxicity

A. Majouga, Yu. V. Fedorov, D. Skvortsov, 2016, Arabian Journal of Chemistry.

Synthesis and biological testing of (5Z)-2-aryl-5-arylmethylidene-3,5-dihydro-4H-imidazol-4-ones as antimitotic agents

A. Majouga, S. Kuznetsov, E. Beloglazkina, 2016, Medicinal Chemistry Research.

Synthesis and biological evaluation of PSMA-targeting paclitaxel conjugates.

Anastasia V Aladinskaya, V. Koteliansky, Y. Ivanenkov, 2019, Bioorganic & medicinal chemistry letters.

Synthesis and electrochemical study of 3- and 4-(2-pyridyl)-1,3-benzothiazole complexes with transition metals (CoII, NiII, and CuII). Molecular structure of bis{(4-(2-pyridyl)-1,3-benzothiazole)copper(ii)} tetraacetate

I. V. Yudin, N. Zyk, A. Moiseeva, 2008 .

Electrochemical Detection of a Novel Pt(IV) Prodrug with the Metronidazole Axial Ligand in the Hypoxic Area.

V. N. Nikitina, D. Sakharov, M. Soldatov, 2022, Inorganic chemistry.

Photoinduced Reduction of Novel Dual-Action Riboplatin Pt(IV) Prodrug.

V. N. Nikitina, A. Majouga, K. Y. Vlasova, 2023, ACS applied materials & interfaces.

ELECTROPHILIC SULFAMATOSULFENYLATION OF OLEFINS

N. S. Zefirov, A. Kutateladze, N. Zyk, 1987 .

Reaction of Bicyclo[2.2.1]hepta-2,5-diene with the Arenesulfenamide—Phosphorus(V) Oxohalide System: Chemo-, Regio-, and Stereoselectivity.

I. F. Leshcheva, E. Beloglazkina, N. Zyk, 2003 .

Synthesis and biological evaluation of Doxorubicin-containing conjugate targeting PSMA.

Anastasia V Aladinskaya, V. Koteliansky, Y. Ivanenkov, 2019, Bioorganic & medicinal chemistry letters.

Tetradentate diamido-bis-sulfide ligands on the base of o-aminobenzenethiol and their complexation with NiII, CoII, CuII chlorides in DMF solution and on the gold electrode surface

V. Frolov, M. Egorov, A. Majouga, 2009 .

New type of organic/gold nanohybrid material: Preparation, properties and application in catalysis

K. Maslakov, A. Majouga, E. Beloglazkina, 2015 .

Synthesis and Biological Evaluation of PSMA Ligands with Aromatic Residues and Fluorescent Conjugates Based on Them.

O. Dontsova, A. Garanina, V. Pokrovsky, 2021, Journal of medicinal chemistry.

A new approach to the synthesis of ligands of asialoglycoprotein receptor for targeted delivery of oligonucleotides to hepatocytes

V. Koteliansky, A. Majouga, T. Zatsepin, 2015, Russian Chemical Bulletin.

Development of liver cell-targeted drug delivery systems: experimental approaches

A. Tonevitsky, A. Nazarenko, Y. Ivanenkov, 2017 .

Synthesis and Preclinical Evaluation of Small-Molecule Prostate-Specific Membrane Antigen-Targeted Abiraterone Conjugate

V. Pokrovsky, A. Majouga, A. Vaneev, 2022, Molecules.

5-(Pyridylmethylidene)-substituted 2-thiohydantoins and their complexes with CuII, NiII, and CoII: Synthesis, electrochemical study, and adsorption on the cystamine-modified gold surface

I. V. Yudin, A. Majouga, K. Butin, 2006 .

Synthesis, Characterization, and Preclinical Evaluation of a Small-Molecule Prostate-Specific Membrane Antigen-Targeted Monomethyl Auristatin E Conjugate.

A. Zamyatnin, V. Pokrovsky, A. Majouga, 2021, Journal of medicinal chemistry.

A simple new synthesis of thiobisamines

T. Kutateladze, N. Zefirov, A. Kutateladze, 1991 .

Design , synthesis and biological evaluation of novel potent MDM 2 / p 53 small-molecule inhibitors

A. Tonevitsky, O. Dontsova, Y. Ivanenkov, 2014 .

Structure determination of bis{(4Z)-1-(2-azidoethyl)-4-[(pyridin-2-yl)methylidene]-2-thiolatoimidazol-5(4H)-one}dicopper chloride from X-ray powder diffraction data

E. Antipov, A. Majouga, N. Zyk, 2013, Russian Chemical Bulletin.

Synthesis of new derivatives of 5,6,7,8-tetrahydro-1,6-naphthyridines and their pharmacological properties

V. Vinokurov, P. Klodt, N. Zyk, 2005 .

Synthetic Approaches to Physiologically Active Polycyclic Compounds: VI. Synthesis of 1-[(2R,3S)-N-Benzoyl-phenylisoseryloxy]-4,4-dimethyladamantane

N. Zyk, O. Zefirova, N. Zyk, 2005 .

Synthesis and biotests of 2-aryl-5-arylmethylidene-substituted 1,3-oxazol-5(4H)-ones and N-methyl-3,5-dihydro-4H-imidazol-4-ones as combretastatin A-4 analogs

A. Majouga, E. Beloglazkina, N. Zefirov, 2015, Russian Chemical Bulletin.

Dipyrrolo[1,2-a;2':,1'-c]pyrazines. 7. Electrophilic Substitution of Dipyrrolo[1,2-a;2',1'-c]pyrazines and 5,6-Dihydrodipyrrolo[1,2-a;2',1'-c]pyrazines via Formylation of Dipyrrolo[1,2-a;2':,1'-c]pyrazines

A. P. Pleshkova, S. Vatsadze, N. Zyk, 2003 .

Synthesis and electrochemical study of 2-(2-pyridyl)benzothiazole complexes with transition metals (CoII, NiII, and CuII). Molecular structure of aquabis[2-(2-pyridyl)benzothiazole]copper(II) diperchlorate

I. V. Yudin, A. Majouga, N. Zyk, 2006 .

Synthesis 5-(pyrazolin-3-ylmethylidene)-2-thiohydantoins and 2-alkylsulfanyl-5-(pyrazolin-3-ylmethylidene)-3,5-dihydro-4H-imidazol-4-ones

A. Majouga, E. Beloglazkina, N. Zyk, 2017, Russian Chemical Bulletin.

Sulfur-containing terpyridine derivatives: synthesis, coordination properties, and adsorption on the gold surface

A. Majouga, D. Pichugina, E. Beloglazkina, 2012, Russian Chemical Bulletin.

Polypeptide-Based Molecular Platform and Its Docetaxel/Sulfo-Cy5-Containing Conjugate for Targeted Delivery to Prostate Specific Membrane Antigen

A. Majouga, V. A. Roznyatovsky, Y. Grishin, 2020, Molecules.

Arylselenenation of conjugated dienes by arylselenenamides in the presence of phosphorus(V) oxyhalides

E. Beloglazkina, N. Zyk, R. L. Antipin, 2007 .

Arylselenenation of Conjugated Dienes by Arylselenamides in the Presence of Phosphorus(V) Oxyhalides.

E. Beloglazkina, N. Zyk, R. L. Antipin, 2007 .

Synthesis and physicochemical study of NiII complexes with tetradentate acyclic and macrocyclic N2S2 ligands as thiosalen analogs

K. Butin, N. Zyk, A. Moiseeva, 2005 .

Choice of the optimal synthetic approach for the polypeptide ligands of prostatic specific membrane antigen preparation

A. Majouga, E. Beloglazkina, N. Zyk, 2023, Mendeleev Communications.

Ullmann-type C-Se cross-coupling in the hydantoin family: Synthesis, mechanistic studies, and tests of biological activity.

D. Laikov, A. Majouga, D. Skvortsov, 2020, Journal of Organic Chemistry.

Copper-Promoted C-Se Cross-Coupling of 2-Selenohydantoins with Arylboronic Acids in an Open Flask.

Y. Ivanenkov, A. Majouga, D. Skvortsov, 2019, ACS combinatorial science.

New 2-(2-pyridyl)-substituted benzothiazoles with polyethylene glycol substituents

V. V. Shorokhov, I. V. Yudin, N. Zyk, 2019, Russian Chemical Bulletin.