V. Subramanian

发表

A C-terminal Region Dictates the Apical Plasma Membrane Targeting of the Human Sodium-dependent Vitamin C Transporter-1 in Polarized Epithelia*[boxs]

J. Marchant, H. Said, Michael J. Boulware, 2004, Journal of Biological Chemistry.

Cell Biology of the Human Thiamine Transporter-1 (hTHTR1)

J. Marchant, I. Parker, H. Said, 2003, The Journal of Biological Chemistry.

Enterotoxigenic Escherichia coli heat labile enterotoxin inhibits intestinal ascorbic acid uptake via a cAMP-dependent NF-κB-mediated pathway.

J. Marchant, G. A. Subramenium, H. Said, 2019, American journal of physiology. Gastrointestinal and liver physiology.

Targeting and Trafficking of the Human Thiamine Transporter-2 in Epithelial Cells*

J. Marchant, H. Said, V. Subramanian, 2006, Journal of Biological Chemistry.

Disintegration of colonic epithelial tight junction in uremia: a likely cause of CKD-associated inflammation.

N. Vaziri, Z. Ni, V. Subramanian, 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Novel Physiological Function of Sphingomyelin in Plasma

P. Subbaiah, K. Wang, Kewei Wang, 1999, The Journal of Biological Chemistry.

Apical membrane targeting and trafficking of the human proton-coupled transporter in polarized epithelia.

J. Marchant, H. Said, V. Subramanian, 2008, American journal of physiology. Cell physiology.

Mechanism of folate transport across the human colonic basolateral membrane.

P. Dudeja, H. Said, V. Subramanian, 1997, American journal of physiology. Gastrointestinal and liver physiology.

Adaptive regulation of intestinal folate uptake: effect of dietary folate deficiency.

S. Rubin, F. Sirotnak, L. Matherly, 2000, American journal of physiology. Cell physiology.

Folate uptake in the human intestine: Promoter activity and effect of folate deficiency

H. Said, V. Subramanian, N. Chatterjee, 2003, Journal of cellular physiology.

Chronic Nicotine Exposure In Vivo and In Vitro Inhibits Vitamin B1 (Thiamin) Uptake by Pancreatic Acinar Cells

A. Balamurugan, E. Thrower, H. Said, 2015, PloS one.

Role of lecithin-cholesterol acyltransferase in the metabolism of oxidized phospholipids in plasma: studies with platelet-activating factor-acetyl hydrolase-deficient plasma.

M. Liu, P. Subbaiah, M. Miwa, 1999, Biochimica et biophysica acta.

Pyridoxine uptake by colonocytes: a specific and regulated carrier-mediated process.

N. Vaziri, H. Said, V. Subramanian, 2008, American journal of physiology. Cell physiology.

Trans unsaturated fatty acids inhibit lecithin: cholesterol acyltransferase and alter its positional specificity.

M. Liu, P. Subbaiah, V. Subramanian, 1998, Journal of lipid research.

N-Glycosylation is required for Na+-dependent vitamin C transporter functionality.

J. Marchant, H. Said, V. Subramanian, 2008, Biochemical and biophysical research communications.

The human colonic thiamine pyrophosphate transporter (hTPPT) is a glycoprotein and N-linked glycosylation is important for its function.

H. Said, V. Subramanian, S. Nabokina, 2016, Biochimica et biophysica acta.

Adaptive regulation of human intestinal thiamine uptake by extracellular substrate level: a role for THTR-2 transcriptional regulation.

H. Said, V. Subramanian, J. Valle, 2013, American journal of physiology. Gastrointestinal and liver physiology.

Chronic alcohol consumption and intestinal thiamin absorption: effects on physiological and molecular parameters of the uptake process.

H. Said, S. Subramanya, V. Subramanian, 2010, American journal of physiology. Gastrointestinal and liver physiology.

Pancreatic beta cells and islets take up thiamin by a regulated carrier-mediated process: studies using mice and human pancreatic preparations.

K. Maedler, H. Said, V. Subramanian, 2009, American journal of physiology. Gastrointestinal and liver physiology.

Vitamin B1 (thiamine) uptake by human retinal pigment epithelial (ARPE‐19) cells: mechanism and regulation

N. Vaziri, J. Marchant, H. Said, 2007, The Journal of physiology.

Uptake of ascorbic acid by pancreatic acinar cells is negatively impacted by chronic alcohol exposure.

H. Said, V. Subramanian, P. Srinivasan, 2016, American journal of physiology. Cell physiology.

transportparameters of intestinal and renal riboflavin Chronic alcohol feeding inhibits physiological and

S. Subramanya, V. Subramanian, A. Ghosal, 2016 .

Mechanisms involved in the inhibitory effect of chronic alcohol exposure on pancreatic acinar thiamin uptake.

H. Said, V. Subramanian, P. Srinivasan, 2014, American journal of physiology. Gastrointestinal and liver physiology.

Combination of primers used to amplify the respective genes by real-time and semiquantitative PCR

H. Said, S. Subramanya, V. Subramanian, 2013 .

Chronic alcohol feeding inhibits physiological and molecular parameters of intestinal and renal riboflavin transport.

H. Said, S. Subramanya, V. Subramanian, 2013, American journal of physiology. Cell physiology.

Thiamin uptake by pancreatic acinar cells: effect of chronic alcohol feeding/exposure.

H. Said, S. Subramanya, V. Subramanian, 2011, American journal of physiology. Gastrointestinal and liver physiology.

Combination of primers used to amplify open reading frame of the respective genes by real-time and semiquantitative PCR

H. Tsukamoto, H. Said, S. Subramanya, 2010 .

Effect of chronic alcohol feeding on physiological and molecular parameters of renal thiamin transport.

H. Tsukamoto, H. Said, S. Subramanya, 2010, American journal of physiology. Renal physiology.

Mechanisms and regulation of vitamin C uptake: studies of the hSVCT systems in human liver epithelial cells.

Mohammed A. Sadat, H. Said, V. Subramanian, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Membrane targeting and intracellular trafficking of the human sodium-dependent multivitamin transporter in polarized epithelial cells.

J. Marchant, H. Said, Michael J. Boulware, 2009, American journal of physiology. Cell physiology.

Structure/functional aspects of the human riboflavin transporter-3 (SLC52A3): role of the predicted glycosylation and substrate-interacting sites.

H. Said, V. Subramanian, Subrata Sabui, 2017, American journal of physiology. Cell physiology.

MicroRNA-103a regulates sodium-dependent vitamin C transporter-1 expression in intestinal epithelial cells.

J. Marchant, H. Said, V. Subramanian, 2019, The Journal of nutritional biochemistry.

Relative contribution of THTR-1 and THTR-2 in thiamin uptake by pancreatic acinar cells: studies utilizing Slc19a2 and Slc19a3 knockout mouse models.

H. Said, S. Subramanya, V. Subramanian, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Metabolites and growth factors produced by airway epithelial cells induce tolerance in macrophages.

A. Agrawal, S. Agrawal, V. Subramanian, 2022, Life sciences.

Biotin-responsive basal ganglia disease-linked mutations inhibit thiamine transport via hTHTR2: biotin is not a substrate for hTHTR2.

J. Marchant, H. Said, V. Subramanian, 2006, American journal of physiology. Cell physiology.

Thymoquinone, a Dietary Bioactive Compound, Exerts Anti-Inflammatory Effects in Colitis by Stimulating Expression of the Colonic Epithelial PPAR-γ Transcription Factor

T. Adrian, S. Ojha, S. Attoub, 2021, Nutrients.

Vitamin C Enhances Antiviral Functions of Lung Epithelial Cells

A. Agrawal, S. Agrawal, F. Rahmatpanah, 2021, Biomolecules.

Impact of IL-21-associated peripheral and brain crosstalk on the Alzheimer’s disease neuropathology

J. Baulch, A. Agrawal, S. Agrawal, 2022, Cellular and Molecular Life Sciences.

Effect of Lipopolysaccharide and TNFα on Neuronal Ascorbic Acid Uptake

M. Kitazawa, A. Agrawal, J. Marchant, 2021, Mediators of inflammation.

Tumor necrosis factor alpha reduces intestinal vitamin C uptake: a role for NF-κB-mediated signaling.

J. Marchant, G. A. Subramenium, H. Said, 2018, American journal of physiology. Gastrointestinal and liver physiology.

Nutrition, Metabolism Tumor necrosis factor alpha reduces intestinal vitamin C uptake: a role for NF- (cid:2) B-mediated signaling

J. Marchant, G. A. Subramenium, H. Said, 2018 .

Mammalian colonocytes possess a carrier-mediated mechanism for uptake of vitamin B3 (niacin): studies utilizing human and mouse colonic preparations.

Jeyan S. Kumar, H. Said, M. Kashyap, 2013, American journal of physiology. Gastrointestinal and liver physiology.

Molecular determinants dictating cell surface expression of the human sodium-dependent vitamin C transporter-2 in human liver cells.

J. Marchant, H. Said, V. Subramanian, 2010, American journal of physiology. Gastrointestinal and liver physiology.

Novel nonsense mutation (p.Ile411Metfs*12) in the SLC19A2 gene causing Thiamine Responsive Megaloblastic Anemia in an Indian patient.

P. Varalakshmi, B. Ashokkumar, H. Said, 2016, Clinica chimica acta; international journal of clinical chemistry.

Enteropathogenic Escherichia coli Infection Inhibits Intestinal Ascorbic Acid Uptake via Dysregulation of Its Transporter Expression

J. Marchant, Carly Hennessey, M. Gareau, 2020, Digestive Diseases and Sciences.

Molecular mechanism(s) involved in differential expression of vitamin C transporters along the intestinal tract.

J. Marchant, H. Said, V. Subramanian, 2017, American journal of physiology. Gastrointestinal and liver physiology.

The human sodium-dependent vitamin C transporter 1 (hSVCT1) contributes to cellular uptake

H. Said, Marchant, V. Subramanian, 2013 .

Modulation of Function of Sodium-Dependent Vitamin C Transporter 1 (SVCT1) by Rab8a in Intestinal Epithelial Cells: Studies Utilizing Caco-2 Cells and Rab8a Knockout Mice

A. Harada, J. Marchant, H. Said, 2013, Digestive Diseases and Sciences.

Characterization of the 5' regulatory region of the human sodium-dependent multivitamin transporter, hSMVT.

S. Rubin, S. Dey, H. Said, 2002, Biochimica et biophysica acta.

Glyoxalate reductase/hydroxypyruvate reductase interacts with the sodium-dependent vitamin C transporter-1 to regulate cellular vitamin C homeostasis.

H. Moradi, J. Marchant, H. Said, 2013, American journal of physiology. Gastrointestinal and liver physiology.

Inhibition of intestinal biotin absorption by chronic alcohol feeding: cellular and molecular mechanisms

H. Said, S. Subramanya, V. Subramanian, 2011 .

Inhibition of intestinal biotin absorption by chronic alcohol feeding: cellular and molecular mechanisms.

H. Said, S. Subramanya, V. Subramanian, 2011, American journal of physiology. Gastrointestinal and liver physiology.

Chronic alcohol exposure negatively impacts the physiological and molecular parameters of the renal biotin reabsorption process.

H. Said, S. Subramanya, V. Subramanian, 2011, American journal of physiology. Renal physiology.

Cellular and molecular mechanisms 2

H. Said, S. Subramanya, V. Subramanian, 2010 .

Role of the putative N-glycosylation and PKC-phosphorylation sites of the human sodium-dependent multivitamin transporter (hSMVT) in function and regulation.

H. Said, V. Subramanian, A. Ghosal, 2011, Biochimica et Biophysica Acta.

Comparative analysis of ontogenic changes in renal and intestinal biotin transport in the rat.

H. Said, V. Subramanian, S. Nabokina, 2003, American journal of physiology. Renal physiology.

Salmonella Typhimurium Infection Reduces the Ascorbic Acid Uptake in the Intestine

S. Subramanya, V. Subramanian, Trevor Teafatiller, 2023, Mediators of inflammation.

Mutations in SLC5A6 associated with brain, immune, bone, and intestinal dysfunction in a young child

H. Said, P. Benke, V. Subramanian, 2017, Human Genetics.

Differentiation-dependent regulation of intestinal vitamin B(2) uptake: studies utilizing human-derived intestinal epithelial Caco-2 cells and native rat intestine.

C. Lytle, H. Said, S. Subramanya, 2013, American journal of physiology. Gastrointestinal and liver physiology.

Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells.

J. Marchant, H. Said, V. Subramanian, 2011, American journal of physiology. Gastrointestinal and liver physiology.

Identification of transmembrane protein 237 as a novel interactor with the intestinal riboflavin transporter-3 (RFVT-3): role in functionality and cell biology.

H. Said, V. Subramanian, Subrata Sabui, 2019, American journal of physiology. Cell physiology.

Effect of the proinflammatory cytokine TNF-α on intestinal riboflavin uptake: inhibition mediated via transcriptional mechanism(s).

H. Said, R. Kapadia, V. Subramanian, 2018, American journal of physiology. Cell physiology.

Role of MicroRNA-423-5p in posttranscriptional regulation of the intestinal riboflavin transporter-3.

R. Lakhan, H. Said, V. Subramanian, 2017, American journal of physiology. Gastrointestinal and liver physiology.

Conditional (intestinal-specific) knockout of the riboflavin transporter-3 (RFVT-3) impairs riboflavin absorption.

C. Lytle, H. Said, V. Subramanian, 2016, American journal of physiology. Gastrointestinal and liver physiology.

Molecular Mechanisms Mediating the Adaptive Regulation of Intestinal Riboflavin Uptake Process

H. Said, R. Kapadia, V. Subramanian, 2015, PloS one.

Identification of residues/sequences in the human riboflavin transporter-2 that is important for function and cell biology

H. Said, R. Kapadia, V. Subramanian, 2015, Nutrition & Metabolism.

Differential expression of human riboflavin transporters -1, -2, and -3 in polarized epithelia: a key role for hRFT-2 in intestinal riboflavin uptake.

J. Marchant, H. Said, T. Ma, 2011, Biochimica et biophysica acta.

Association of PDZ-containing protein PDZD11 with the human sodium-dependent multivitamin transporter.

H. Said, V. Subramanian, S. Nabokina, 2011, American journal of physiology. Gastrointestinal and liver physiology.

Mechanism of thiamine uptake by human colonocytes: studies with cultured colonic epithelial cell line NCM460.

E. Neufeld, M. Moyer, P. Dudeja, 2001, American journal of physiology. Gastrointestinal and liver physiology.

Structure-function characterization of the human mitochondrial thiamin pyrophosphate transporter (hMTPPT; SLC25A19): Important roles for Ile(33), Ser(34), Asp(37), His(137) and Lys(291).

H. Said, R. Kapadia, V. Subramanian, 2016, Biochimica et biophysica acta.

Tight junction targeting and intracellular trafficking of occludin in polarized epithelial cells.

J. Marchant, D. Ye, H. Said, 2007, American journal of physiology. Cell physiology.

SLC52A2 [p.P141T] and SLC52A3 [p.N21S] causing Brown-Vialetto-Van Laere Syndrome in an Indian patient: First genetically proven case with mutations in two riboflavin transporters.

P. Varalakshmi, B. Ashokkumar, H. Said, 2016, Clinica chimica acta; international journal of clinical chemistry.

Effect of clinical mutations on functionality of the human riboflavin transporter-2 (hRFT-2).

H. Said, V. Subramanian, S. Nabokina, 2012, Molecular genetics and metabolism.

Intracellular Trafficking and Membrane Targeting Mechanisms of the Human Reduced Folate Carrier in Mammalian Epithelial Cells* 210

J. Marchant, I. Parker, H. Said, 2002, The Journal of Biological Chemistry.

Effect of the Cigarette Smoke Component, 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK), on Physiological and Molecular Parameters of Thiamin Uptake by Pancreatic Acinar Cells

H. Said, V. Subramanian, P. Srinivasan, 2013, PloS one.

Inhibition of intestinal ascorbic acid uptake by lipopolysaccharide is mediated via transcriptional mechanisms.

H. Moradi, J. Marchant, H. Said, 2018, Biochimica et biophysica acta. Biomembranes.

Upregulation of Vitamin C Transporter Functional Expression in 5xFAD Mouse Intestine

J. Baulch, A. Agrawal, J. Marchant, 2021, Nutrients.

Expression and functional contribution of hTHTR-2 in thiamin absorption in human intestine.

J. Marchant, K. Balamurugan, H. Said, 2004, American journal of physiology. Gastrointestinal and liver physiology.

Intracellular trafficking/membrane targeting of human reduced folate carrier expressed in Xenopus oocytes.

J. Marchant, I. Parker, H. Said, 2001, American journal of physiology. Gastrointestinal and liver physiology.

Sodium Butyrate Enhances Intestinal Riboflavin Uptake via Induction of Expression of Riboflavin Transporter-3 (RFVT3)

H. Said, V. Subramanian, Subrata Sabui, 2018, Digestive Diseases and Sciences.

Adaptive regulation of pancreatic acinar mitochondrial thiamin pyrophosphate uptake process: possible involvement of epigenetic mechanism(s).

H. Said, R. Kapadia, V. Subramanian, 2017, American journal of physiology. Gastrointestinal and liver physiology.

Molecular mechanisms involved in the adaptive regulation of the colonic thiamin pyrophosphate uptake process.

H. Said, V. Subramanian, P. Srinivasan, 2017, American journal of physiology. Cell physiology.

Histone deacetylase inhibitors regulate vitamin C transporter functional expression in intestinal epithelial cells.

H. Moradi, J. Marchant, V. Subramanian, 2021, Journal of Nutritional Biochemistry.

Valproic acid upregulates sodium-dependent vitamin C transporter-2 functional expression in neuronal cells.

M. Kitazawa, V. Subramanian, S. Subramanian, 2022, Life sciences.

Differentiation-dependent regulation of the intestinal folate uptake process: studies with Caco-2 cells and native mouse intestine.

H. Said, V. Subramanian, J. Reidling, 2008, American journal of physiology. Cell physiology.

Modulation of the positional specificity of lecithin-cholesterol acyltransferase by the acyl group composition of its phosphatidylcholine substrate: role of the sn-1-acyl group.

M. Liu, P. Subbaiah, V. Subramanian, 1998, Biochemistry.

Association of TM4SF4 with the Human Thiamine Transporter-2 in Intestinal Epithelial Cells

H. Said, V. Subramanian, S. Nabokina, 2014, Digestive Diseases and Sciences.

Expression and promoter analysis of SLC19A2 in the human intestine.

P. Dudeja, H. Said, V. Subramanian, 2002, Biochimica et biophysica acta.

Vitamin C transport in neurons and epithelia is regulated by secretory carrier-associated membrane protein-2 (SCAMP2).

M. Rashid, J. Marchant, Yaping Lin-Moshier, 2023, International journal of biological macromolecules.

Cis-Nerolidol Inhibits MAP Kinase and NF-κB Signaling Pathways and Prevents Epithelial Tight Junction Dysfunction in Colon Inflammation: In Vivo and In Vitro Studies

T. Adrian, S. Ojha, Balaji Venkataraman, 2023, Molecules.

Molecular Docking Identifies 1,8-Cineole (Eucalyptol) as A Novel PPARγ Agonist That Alleviates Colon Inflammation

T. Adrian, R. Patil, T. Rizvi, 2023, International journal of molecular sciences.

Calsyntenin-3 interacts with the sodium-dependent vitamin C transporter-2 to regulate vitamin C uptake.

M. Kitazawa, J. Marchant, Carlos J. Rodriguez-Ortiz, 2021, International journal of biological macromolecules.

T1881 Pyridoxine Uptake By Colonocytes: A Specific and Regulated Carrier-Mediated Process

N. Vaziri, H. Said, V. Subramanian, 2008 .

Correction: Mitochondrial Uptake of Thiamin Pyrophosphate: Physiological and Cell Biological Aspects

J. Marchant, Yaping Lin-Moshier, H. Said, 2017, PloS one.

Mitochondrial Uptake of Thiamin Pyrophosphate: Physiological and Cell Biological Aspects

J. Marchant, Yaping Lin-Moshier, H. Said, 2013, PloS one.

Molecular identification and functional characterization of the human colonic thiamine pyrophosphate transporter.

Katsuhisa Inoue, H. Said, H. Yuasa, 2017, The Journal of Biological Chemistry.

Thiamine Pyrophosphate Transporter Characterization of the Human Colonic Molecular Identification and Functional Membrane Biology

Katsuhisa Inoue, H. Said, H. Yuasa, 2014 .

Polarized expression of members of the solute carrier SLC19A gene family of water-soluble multivitamin transporters: implications for physiological function.

J. Marchant, H. Said, Michael J. Boulware, 2003, The Biochemical journal.

Nedd4-1 regulates human sodium-dependent vitamin C transporter-2 functional expression in neuronal and epithelial cells.

M. Kitazawa, A. Agrawal, V. Subramanian, 2023, Journal of Nutritional Biochemistry.

The human colonic thiamine pyrophosphate transporter (hTPPT) is a glycoprotein and N-linked glycosylation is important for its function.

H. Said, V. Subramanian, S. Nabokina, 2016, Biochimica et biophysica acta.

Disintegration of colonic epithelial tight junction in uremia: a likely cause of CKD-associated inflammation.

N. Vaziri, Z. Ni, V. Subramanian, 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Targeting and intracellular trafficking of clinically relevant hTHTR1 mutations in human cell lines.

J. Marchant, H. Said, V. Subramanian, 2007, Clinical science.

Intracellular trafficking/membrane targeting of human reduced folate carrier expressed in Xenopus oocytes.

V. Subramanian, Hamid M. Said, Jonathan S. Marchant, 2001, American journal of physiology. Gastrointestinal and liver physiology.

Functional expression of a high affinity mammalian hepatic choline/organic cation transporter.

R. Green, K. D. Chi, V. Subramanian, 2000, Journal of lipid research.

Molecular Mechanisms Mediating the Adaptive Regulation of Intestinal Riboflavin Uptake Process

H. Said, R. Kapadia, V. Subramanian, 2015, PloS one.

Conditional (intestinal-specific) knockout of the riboflavin transporter-3 (RFVT-3) impairs riboflavin absorption.

C. Lytle, H. Said, V. Subramanian, 2016, American journal of physiology. Gastrointestinal and liver physiology.

Relative contribution of THTR-1 and THTR-2 in thiamin uptake by pancreatic acinar cells: studies utilizing Slc19a2 and Slc19a3 knockout mouse models.

H. Said, S. Subramanya, V. Subramanian, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Phytochemical Compounds as Promising Therapeutics for Intestinal Fibrosis in Inflammatory Bowel Disease: A Critical Review

S. Ojha, Balaji Venkataraman, S. Subramanya, 2024, Nutrients.

Differentiation-dependent regulation of intestinal vitamin B 2 uptake : Studies utilizing 1 human-derived intestinal epithelial Caco 2 cells and native rat intestine 2 3

C. Lytle, H. Said, S. Subramanya, 2013 .