D. Ruano

发表

Functional Gene Group Analysis Reveals a Role of Synaptic Heterotrimeric G Proteins in Cognitive Ability

Gonçalo R. Abecasis, L. Niels Cornelisse, Danielle Posthuma, 2010, American journal of human genetics.

Recurrent Coding Sequence Variation Explains Only A Small Fraction of the Genetic Architecture of Colorectal Cancer

Ian J. Deary, Archie Campbell, Sergi Castellví-Bel, 2015, Scientific Reports.

Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia

R. Vossen, Arnoud Boot, I. Tomlinson, 2017, British Journal of Cancer.

Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia

R. Vossen, I. Tomlinson, B. Wolffenbuttel, 2017, British Journal of Cancer.

Neoantigen-specific immunity in low mutation burden colorectal cancers of the consensus molecular subtype 4

Marieke E. Ijsselsteijn, S. H. van der Burg, R. van der Breggen, 2019, Genome Medicine.

Molecular Analysis of Gene Fusions in Bone and Soft Tissue Tumors by Anchored Multiplex PCR-Based Targeted Next-Generation Sequencing.

A. Cleton-Jansen, T. van Wezel, J. Bovée, 2018, The Journal of molecular diagnostics : JMD.

Local and systemic immune profiles of human pancreatic ductal adenocarcinoma revealed by single-cell mass cytometry

H. Morreau, A. Vahrmeijer, B. Lelieveldt, 2022, Journal for ImmunoTherapy of Cancer.

NR4A2 and schizophrenia: Lack of association in a Portuguese/Brazilian study

M. Hutz, M. Azevedo, J. Palha, 2004, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype.

M. Kersten, Stefan Boehringer, A. van den Berg, 2021, Blood advances.

A Paradoxical Role for Regulatory T Cells in the Tumor Microenvironment of Pancreatic Cancer

Marieke E. Ijsselsteijn, H. Morreau, A. Vahrmeijer, 2022, Cancers.

Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia

R. Vossen, I. Tomlinson, B. Wolffenbuttel, 2017, British Journal of Cancer.

Revisiting immune escape in colorectal cancer in the era of immunotherapy

Marieke E. Ijsselsteijn, H. Morreau, C. Sautès-Fridman, 2019, British Journal of Cancer.

Digenic inheritance of MSH6 and MUTYH variants in familial colorectal cancer

N. de Wind, H. Morreau, T. van Wezel, 2020, Genes, chromosomes & cancer.

Cancer-specific T helper shared and neo-epitopes uncovered by expression of the MHC class II master regulator CIITA.

P. V. van Veelen, P. J. van den Elsen, F. Ossendorp, 2022, Cell reports.

Genetic Stability of Driver Alterations in Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type and Their Relapses: A Rationale for the Use of Molecular-Based Methods for More Effective Disease Monitoring

T. van Wezel, R. Willemze, H. Veelken, 2022, Cancers.

Targeted DNA sequencing to identify genetic aberrations in glioblastoma that underlie venous thromboembolism; a cohort study.

M. Taphoorn, H. Versteeg, J. Koekkoek, 2022, Thrombosis research.

γδ T cells are effectors of immunotherapy in cancers with HLA class I defects

Marieke E. Ijsselsteijn, L. Wessels, J. G. van den Berg, 2023, Nature.

Association of the gene encoding neurogranin with schizophrenia in males.

M. Hutz, C. Pato, M. Azevedo, 2008, Journal of psychiatric research.

Integral analysis of p53 and its value as prognostic factor in sporadic colon cancer

H. Morreau, T. van Wezel, R. Tollenaar, 2013, BMC Cancer.

Revisiting Thyroid Hormones in Schizophrenia

M. Azevedo, A. T. Pereira, J. Palha, 2012, Journal of thyroid research.

Target-enriched next-generation sequencing reveals differences between primary and secondary ovarian tumors in formalin-fixed, paraffin-embedded tissue.

G. Fleuren, H. Morreau, T. van Wezel, 2015, The Journal of molecular diagnostics : JMD.

Allelic Switching of DLX5, GRB10, and SVOPL during Colorectal Cancer Tumorigenesis

Arnoud Boot, H. Morreau, T. van Wezel, 2019, International journal of genomics.

Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion.

Dachuan Huang, C. Ong, B. Teh, 2015, The Journal of clinical endocrinology and metabolism.

Identification of a neo-epitope dominating endogenous CD8 T cell responses to MC-38 colorectal cancer

D. Filippov, P. V. van Veelen, K. Franken, 2019, Oncoimmunology.

Rapid KRAS, EGFR, BRAF and PIK3CA Mutation Analysis of Fine Needle Aspirates from Non-Small-Cell Lung Cancer Using Allele-Specific qPCR

K. Rabe, P. Nederlof, J. Annema, 2011, PloS one.

Distinct Patterns of Somatic Mosaicism in the APC Gene in Neoplasms From Patients With Unexplained Adenomatous Polyposis.

W. Dinjens, H. Morreau, T. van Wezel, 2017, Gastroenterology.

Validation and Implementation of BRCA1/2 Variant Screening in Ovarian Tumor Tissue.

C. V. van Asperen, T. van Wezel, T. Bosse, 2018, The Journal of molecular diagnostics : JMD.

Optimizing mutation and fusion detection in Non-Small Cell Lung Cancer by sequential DNA and RNA sequencing.

F. Smedts, A. Cleton-Jansen, T. van Wezel, 2020, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

CD103 and CD39 coexpression identifies neoantigen-specific cytotoxic T cells in colorectal cancers with low mutation burden

Marieke E. Ijsselsteijn, S. H. van der Burg, R. van der Breggen, 2023, Journal for ImmunoTherapy of Cancer.

Colorectal cancer risk variants on 11q23 and 15q13 are associated with unexplained adenomatous polyposis

A. Wagner, H. Morreau, T. van Wezel, 2013, Journal of Medical Genetics.

Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell cycle progression in a preclinical model

J. Rip, R. González-Prieto, A. Vertegaal, 2022, Gut.

Genomic Characterization of Vulvar (Pre)cancers Identifies Distinct Molecular Subtypes with Prognostic Significance

J. Ordi, T. van Wezel, T. Bosse, 2017, Clinical Cancer Research.

The ATXN1 and TRIM31 genes are related to intelligence in an ADHD background: Evidence from a large collaborative study totaling 4,963 Subjects

David M. Evans, I. Deary, B. Franke, 2010, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients

P. Devilee, A. Wagner, H. Morreau, 2016, PloS one.

Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers

P. Devilee, A. Wagner, H. Morreau, 2015, European Journal of Human Genetics.

Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer

H. Morreau, T. van Wezel, M. Ligtenberg, 2014, European Journal of Human Genetics.

Genome Haploidisation with Chromosome 7 Retention in Oncocytic Follicular Thyroid Carcinoma

E. Jordanova, H. Morreau, T. van Wezel, 2012, PloS one.

Molecular Background of Colorectal Tumors From Patients With Lynch Syndrome Associated With Germline Variants in PMS2.

H. Morreau, T. van Wezel, C. Tops, 2018, Gastroenterology.

Practical guidance for mismatch repair-deficiency testing in endometrial cancer

H. Morreau, T. van Wezel, T. Bosse, 2016, Annals of oncology : official journal of the European Society for Medical Oncology.

γδ T cells are effectors of immune checkpoint blockade in mismatch repair-deficient colon cancers with antigen presentation defects

Marieke E. Ijsselsteijn, L. Wessels, T. Schumacher, 2021, bioRxiv.

Prevalence and Prognosis of Lynch Syndrome and Sporadic Mismatch Repair Deficiency in Endometrial Cancer

H. Putter, T. Bosse, L. Mileshkin, 2021, Journal of the National Cancer Institute.

Practical guidance for mismatch repair-deficiency testing in endometrial cancer.

H. Morreau, T. van Wezel, T. Bosse, 2017 .

Tumor-Infiltrating T Cells Can Be Expanded Successfully from Primary Uveal Melanoma after Separation from Their Tumor Environment

S. H. van der Burg, G. Luyten, P. A. van der Velden, 2022, Ophthalmology science.

Transthyretin: no association between serum levels or gene variants and schizophrenia.

M. Hutz, C. Pato, M. Azevedo, 2007, Journal of psychiatric research.

Neoantigen-specific immunity in low mutation burden colorectal cancers of the consensus molecular subtype 4

Marieke E. Ijsselsteijn, S. H. van der Burg, R. van der Breggen, 2019, Genome Medicine.

Family‐based and case‐control studies reveal no association of lipocalin‐type prostaglandin D2 synthase with schizophrenia

M. Hutz, C. Pato, M. Azevedo, 2007, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Cell-of-origin classification using the Hans and Lymph2Cx algorithms in primary cutaneous large B-cell lymphomas

A. van den Berg, A. Diepstra, T. van Wezel, 2022, Virchows Archiv.

Low frequency of POLD1 and POLE exonuclease domain variants in patients with multiple colorectal polyps

H. Morreau, T. van Wezel, H. Vasen, 2019, Molecular genetics & genomic medicine.

Somatic mutation profiles in primary colorectal cancers and matching ovarian metastases: Identification of driver and passenger mutations

G. Fleuren, H. Morreau, T. van Wezel, 2016, The journal of pathology. Clinical research.

Yield and costs of molecular diagnostics on thyroid cytology slides in the Netherlands, adapting the Bethesda classification

H. Morreau, T. van Wezel, A. Schepers, 2021, Endocrinology, diabetes & metabolism.

Enrichment of colibactin-associated mutational signatures in unexplained colorectal polyposis patients

Arnoud Boot, H. Morreau, T. van Wezel, 2023, medRxiv.

Ubiquitin associated protein 1 is a risk factor for frontotemporal lobar degeneration

D. Neary, M. Rossor, N. Cairns, 2009, Neurobiology of Aging.