Xiaoqin Li

发表

Selective Oxidations of Cyperenoic Acid by Slightly Reshaping the Binding Pocket of Cytochrome P450 BM3

Jun Tang, Bin Qin, Yuxin Li, 2018 .

Kinetics of sulforaphane in mice after consumption of sulforaphane-enriched broccoli sprout preparation.

Tao Zhang, S. Schwartz, Duxin Sun, 2013, Molecular Nutrition & Food Research.

Novel inhibitors of bacterial virulence: development of 5,6-dihydrobenzo[h]quinazolin-4(3H)-ones for the inhibition of group A streptococcal streptokinase expression.

R. Sorenson, Wenpeng Zhang, Duxin Sun, 2013, Bioorganic & medicinal chemistry.

Pramipexole Derivatives as Potent and Selective Dopamine D3 Receptor Agonists with Improved Human Microsomal Stability

Shaomeng Wang, Jianyong Chen, Ting Zhao, 2014, ChemMedChem.

Structure-Based Discovery of CF53 as a Potent and Orally Bioavailable Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitor.

Liu Liu, Shaomeng Wang, Chao-yie Yang, 2018, Journal of medicinal chemistry.

Diastereomeric spirooxindoles as highly potent and efficacious MDM2 inhibitors.

J. Deschamps, Liu Liu, Shaomeng Wang, 2013, Journal of the American Chemical Society.

Potent bivalent Smac mimetics: effect of the linker on binding to inhibitor of apoptosis proteins (IAPs) and anticancer activity.

Liu Liu, Shaomeng Wang, Chao-yie Yang, 2011, Journal of medicinal chemistry.

Discovery of 4-((3′R,4′S,5′R)-6″-Chloro-4′-(3-chloro-2-fluorophenyl)-1′-ethyl-2″-oxodispiro[cyclohexane-1,2′-pyrrolidine-3′,3″-indoline]-5′-carboxamido)bicyclo[2.2.2]octane-1-carboxylic Acid (AA-115/APG-115): A Potent and Orally Active Murine Double Minute 2 (MDM2) Inhibitor in Clinical Development

Liu Liu, Shaomeng Wang, Dajun Yang, 2017, Journal of medicinal chemistry.

A potent small-molecule inhibitor of the MDM2-p53 interaction (MI-888) achieved complete and durable tumor regression in mice.

Liu Liu, Shaomeng Wang, D. McEachern, 2013, Journal of medicinal chemistry.

Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor.

Liu Liu, Shaomeng Wang, J. Stuckey, 2017, Journal of medicinal chemistry.

Examination of the Pharmacokinetics of Active Ingredients of Ginger in Humans

S. Zick, B. Wright, Duxin Sun, 2011, The AAPS Journal.

Discovery of CJ-2360 as a Potent and Orally Active Inhibitor of Anaplastic Lymphoma Kinase Capable of Achieving Complete Tumor Regression.

Liu Liu, Shaomeng Wang, Dajun Yang, 2020, Journal of medicinal chemistry.

Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein-Protein Interaction between Menin and Mixed Lineage Leukemia (MLL).

T. Cierpicki, J. Grembecka, Ting Zhao, 2016, Journal of medicinal chemistry.

Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)-Mixed Lineage Leukemia (MLL) Protein-Protein Interaction.

F. Cao, Elizabeth C. Townsend, Hacer Karatas, 2017, Journal of medicinal chemistry.

Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor.

Liu Liu, Shaomeng Wang, J. Stuckey, 2017, Journal of medicinal chemistry.