G. Domány

发表

4-Aryl-3-arylsulfonyl-quinolines as negative allosteric modulators of metabotropic GluR5 receptors: From HTS hit to development candidate.

J. Galambos, G. Keserű, Z. Szakács, 2016, Bioorganic & medicinal chemistry letters.

Discovery of cariprazine (RGH-188): a novel antipsychotic acting on dopamine D3/D2 receptors.

J. Galambos, A. Gere, É. Schmidt, 2012, Bioorganic & medicinal chemistry letters.

Carbamoyloximes as novel non-competitive mGlu5 receptor antagonists.

J. Galambos, B. Kiss, L. Molnár, 2010, Bioorganic & medicinal chemistry letters.

Hit-to-lead optimization of disubstituted oxadiazoles and tetrazoles as mGluR5 NAMs.

B. Kiss, L. Molnár, G. Keserű, 2010, Bioorganic & medicinal chemistry letters.

Synthesis of deuterated dextromethorphan derivatives

H. Bölcskei, M. Mâk, G. Domány, 2008 .

Radiochemical labelling of the dopamine D3 receptor ligand RGH‐1756

B. Gulyás, B. Kiss, J. Sandell, 2000 .

Indole-2-carboxamides as novel NR2B selective NMDA receptor antagonists.

B. Ágai, A. Gere, C. Kiss, 2003, Bioorganic & medicinal chemistry letters.

Quinolinyl- and phenantridinyl-acetamides as bradykinin B1 receptor antagonists.

É. Schmidt, G. Keserű, Ákos Tarcsay, 2012, Bioorganic & medicinal chemistry letters.

NR2B selective NMDA antagonists: the evolution of the ifenprodil-type pharmacophore.

G. Domány, I. Borza, 2006, Current topics in medicinal chemistry.

Synthesis of 2‐phosphinoxidomethyl‐ and 2‐phosphonomethyl glutaric acid derivatives

G. Keglevich, I. Greiner, K. Harsányi, 2005 .

Oxamides as novel NR2B selective NMDA receptor antagonists.

Csilla Horváth, György M Keseru, Csilla Kiss, 2004, Bioorganic & medicinal chemistry letters.

Design of novel multiple-acting ligands towards SERT and 5-HT2C receptors.

A. Gere, B. Kiss, G. Keserű, 2014, Bioorganic & medicinal chemistry letters.

Kynurenic acid amides as novel NR2B selective NMDA receptor antagonists.

A. Gere, S. Kolok, I. Greiner, 2007, Bioorganic & medicinal chemistry letters.

Benzimidazole-2-carboxamides as novel NR2B selective NMDA receptor antagonists.

B. Ágai, A. Gere, S. Kolok, 2006, Bioorganic & medicinal chemistry letters.

Imidazo[1,2-c]quinazolines with lipid peroxidation inhibitory effect

A. Gere, G. Ferenczy, G. Tárkányi, 1998 .

Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: II. behavioural characterisation of RG-15

B. Kiss, G. Pásztor, O. Elekes, 2008, Naunyn-Schmiedeberg's Archives of Pharmacology.

Cariprazine (RGH-188), a Dopamine D3 Receptor-Preferring, D3/D2 Dopamine Receptor Antagonist–Partial Agonist Antipsychotic Candidate: In Vitro and Neurochemical Profile

Eva Schmidt, István Laszlovszky, Béla Kiss, 2010, Journal of Pharmacology and Experimental Therapeutics.

Selective NR1/2B N-methyl-D-aspartate receptor antagonists among indole-2-carboxamides and benzimidazole-2-carboxamides.

B. Ágai, A. Gere, G. Keserü, 2007, Journal of medicinal chemistry.

Cariprazine (RGH-188), a potent D3/D2 dopamine receptor partial agonist, binds to dopamine D3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents

B. Kiss, G. Pásztor, K. Tihanyi, 2011, Neurochemistry International.

Effects of RGH-237 [N-{4-[4-(3-Aminocarbonyl-phenyl)-piperazin-1-yl]-butyl}-4-bromo-benzamide], an Orally Active, Selective Dopamine D3 Receptor Partial Agonist in Animal Models of Cocaine Abuse

B. Kiss, G. Pásztor, K. Tihanyi, 2007, Journal of Pharmacology and Experimental Therapeutics.

Synthesis and Studies of 1,2-Dihydroquinoline Derivatives as Inhibitors of Lipid Peroxidation

A. Gere, K. Takács-Novák, G. Domány, 2003, Arzneimittelforschung.

New 4-arylaminopiperidines with antihypoxic and anticonvulsive activity.

S. Szabó, G. Domány, I. Schön, 1994, Arzneimittel-Forschung.

The influence of 5-HT(2A) activity on a 5-HT(2C) specific in vivo assay used for early identification of multiple acting SERT and 5-HT(2C) receptor ligands.

A. Gere, B. Kiss, G. Keserű, 2016, Bioorganic & medicinal chemistry letters.

Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: I. neurochemical characterisation of RG-15

É. Schmidt, B. Kiss, I. Laszlovszky, 2008, Naunyn-Schmiedeberg's Archives of Pharmacology.

Indole-2-carboxamidines as novel NR2B selective NMDA receptor antagonists.

József Nagy, Csilla Horváth, Csilla Kiss, 2006, Bioorganic & medicinal chemistry letters.

Discovery and Preclinical Characterization of 3-((4-(4-Chlorophenyl)-7-fluoroquinoline-3-yl)sulfonyl)benzonitrile, a Novel Non-acetylenic Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator for Psychiatric Indications.

J. Galambos, G. Balogh, G. Keserű, 2017, Journal of medicinal chemistry.

Discovery of 4-amino-3-arylsulfoquinolines, a novel non-acetylenic chemotype of metabotropic glutamate 5 (mGlu5) receptor negative allosteric modulators.

J. Galambos, B. Kiss, G. Keserű, 2017, European journal of medicinal chemistry.

Cariprazine (RGH-188), a potent D3/D2 dopamine receptor partial agonist, binds to dopamine D3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents

B. Kiss, K. Tihanyi, T. Szabados, 2011, Neurochemistry International.