Sihyung Yang

发表

Pharmacokinetics of drugs in spontaneously or secondary hypertensive rats

E. Oh, Sihyung Yang, Young S. Lee, 2014, Xenobiotica; the fate of foreign compounds in biological systems.

The inward rectifier current inhibitor PA‐6 terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models

M. Vos, S. Verheule, D. Dobrev, 2017, British journal of pharmacology.

Metopimazine is primarily metabolized by a liver amidase in humans

Xiaokun Cai, Sihyung Yang, R. Busby, 2021, Pharmacology research & perspectives.

CYP1A1 and CYP1B1-mediated biotransformation of the antitrypanosomal methamidoxime prodrug DB844 forms novel metabolites through intramolecular rearrangement.

D. Boykin, J. Hall, R. Tidwell, 2014, Journal of pharmaceutical sciences.

Pharmacokinetics, Trypanosoma brucei gambiense Efficacy, and Time of Drug Action of DB829, a Preclinical Candidate for Treatment of Second-Stage Human African Trypanosomiasis

D. Boykin, R. Brun, O. Braissant, 2013, Antimicrobial Agents and Chemotherapy.

Antileishmanial Efficacy and Pharmacokinetics of DB766-Azole Combinations

D. Boykin, K. Werbovetz, Junan Li, 2017, Antimicrobial Agents and Chemotherapy.

Antileishmanial Activity of a Series of N2,N4-Disubstituted Quinazoline-2,4-diamines

D. Kyle, S. Rijal, M. Vanaerschot, 2014, Journal of medicinal chemistry.

Synthesis and pharmacological evaluation of mono-arylimidamides as antileishmanial agents

Arvind Kumar, D. Boykin, Xiaohua Zhu, 2016, Bioorganic & medicinal chemistry letters.

SAR refinement of antileishmanial N(2),N(4)-disubstituted quinazoline-2,4-diamines.

Xiaohua Zhu, K. Werbovetz, Roman Manetsch, 2015, Bioorganic & medicinal chemistry.

Synthesis of novel amide and urea derivatives of thiazol-2-ethylamines and their activity against Trypanosoma brucei rhodesiense.

R. Brun, R. Tidwell, P. T. Weiser, 2016, Bioorganic & medicinal chemistry.

In Vitro and In Vivo Evaluation of 28DAP010, a Novel Diamidine for Treatment of Second-Stage African Sleeping Sickness

D. Boykin, R. Brun, O. Braissant, 2014, Antimicrobial Agents and Chemotherapy.

Sterol profiling of Leishmania parasites using a new HPLC-tandem mass spectrometry-based method and antifungal azoles as chemical probes reveals a key intermediate sterol that supports a branched ergosterol biosynthetic pathway

K. Werbovetz, Michael Zhuo Wang, Chamani Perera, 2022, International journal for parasitology. Drugs and drug resistance.

Sickness of Second-Stage African Sleeping Treatment 28DAP010, a Novel Diamidine for Evaluation of In Vivo and In Vitro

R. Tidwell, M. Ismail, Michael Zhuo Wang, 2014 .

Synthesis and antiprotozoal activity of dicationic 2,6-diphenylpyrazines and aza-analogues.

W. Wilson, D. Boykin, Laixing Hu, 2013, Bioorganic & medicinal chemistry.

Pharmacokinetic Comparison To Determine the Mechanisms Underlying the Differential Efficacies of Cationic Diamidines against First- and Second-Stage Human African Trypanosomiasis

D. Boykin, R. Brun, Huali Wu, 2014, Antimicrobial Agents and Chemotherapy.

Evaluation of Arylimidamides DB1955 and DB1960 as Candidates against Visceral Leishmaniasis and Chagas' Disease: In Vivo Efficacy, Acute Toxicity, Pharmacokinetics, and Toxicology Studies

W. Wilson, D. Boykin, Qiang Liu, 2012, Antimicrobial Agents and Chemotherapy.

Improving eflornithine oral bioavailability and brain uptake by modulating intercellular junctions with an E-cadherin peptide.

Michael Zhuo Wang, Sihyung Yang, Yao Chen, 2019, Journal of pharmaceutical sciences.

A simple and sensitive assay for eflornithine quantification in rat brain using pre-column derivatization and UPLC-MS/MS detection.

Michael Zhuo Wang, K. Peng, Sihyung Yang, 2015, Biomedical chromatography : BMC.