Kyoko Kinami

发表

Iminosugars Inhibit Dengue Virus Production via Inhibition of ER Alpha-Glucosidases—Not Glycolipid Processing Enzymes

R. Dwek, E. Harris, N. Zitzmann, 2016, PLoS neglected tropical diseases.

Gem-difluoromethylated and trifluoromethylated derivatives of DMDP-related iminosugars: synthesis and glycosidase inhibition.

G. Fleet, A. Kato, Kyoko Kinami, 2016, Organic & biomolecular chemistry.

First total synthesis of (+)-broussonetine W: glycosidase inhibition of natural product & analogs.

G. Fleet, A. Kato, Kyoko Kinami, 2016, Organic & biomolecular chemistry.

Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars.

G. Fleet, A. Kato, Kyoko Kinami, 2016, Organic & biomolecular chemistry.

Strategy for designing selective α-l-rhamnosidase inhibitors: Synthesis and biological evaluation of l-DMDP cyclic isothioureas.

N. Toyooka, G. Fleet, A. Kato, 2017, Bioorganic & medicinal chemistry.

Design and Synthesis of Labystegines, Hybrid Iminosugars from LAB and Calystegine, as Inhibitors of Intestinal α-Glucosidases: Binding Conformation and Interaction for ntSI.

S. Hirono, I. Nakagome, Yutaro Tsuji, 2015, The Journal of organic chemistry.

Concise synthesis of calystegines B2 and B3via intramolecular Nozaki-Hiyama-Kishi reaction.

G. Fleet, A. Kato, Kyoko Kinami, 2016, Organic & biomolecular chemistry.

In silico analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay-Sachs disease.

S. Hirono, I. Nakagome, J. Désiré, 2017, Organic & biomolecular chemistry.

Synthesis and Glycosidase Inhibition of Broussonetine M and Its Analogues

G. Fleet, A. Kato, Kyoko Kinami, 2019, Molecules.

Isolation and SAR studies of bicyclic iminosugars from Castanospermum australe as glycosidase inhibitors.

N. Zitzmann, J. L. Kiappes, R. Molyneux, 2015, Phytochemistry.

Synthesis and biological evaluation of α-1-C-4'-arylbutyl-L-arabinoiminofuranoses, a new class of α-glucosidase inhibitors.

Y. Natori, A. Kato, I. Adachi, 2014, Bioorganic & medicinal chemistry letters.

Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4

R. Dwek, E. Harris, M. Buck, 2016, Antiviral research.