Huajian Zhu

发表

Immunoproteasome-selective inhibitors: An overview of recent developments as potential drugs for hematologic malignancies and autoimmune diseases.

Jiankang Zhang, Jian-Jun Xi, Rangxiao Zhuang, 2019, European journal of medicinal chemistry.

Structure and Transport Properties of Water and Hydrated Ions in Nano‐Confined Channels

Huajian Zhu, Yuying Wang, Yiqun Fan, 2019, Advanced Theory and Simulations.

Cascade reaction for 3-pyrrolines and pyrroles from nitroallylic acetates and N-mesyl 2-aminoethanones

H. Zou, Huajian Zhu, Tong Chen, 2013 .

Chameleon-like Behavior of the Directing Group in the Rh(III)-Catalyzed Regioselective C–H Amidation of Indole: An Experimental and Computational Study

Hujun Xie, Shuaizhong Zhang, H. Zou, 2019, ACS Catalysis.

Discovery of 3-(thiophen/thiazole-2-ylthio)pyridine derivatives as multitarget anticancer agents

Shourong Liu, Jiankang Zhang, Jian-Jun Xi, 2019, Medicinal Chemistry Research.

Discovery of novel N-benzylbenzamide derivatives as tubulin polymerization inhibitors with potent antitumor activities.

Zhe-Sheng Chen, Dong-Hua Yang, Shengtao Xu, 2021, European journal of medicinal chemistry.

Design, synthesis and anticancer properties of isocombretapyridines as potent colchicine binding site inhibitors.

Shengtao Xu, Jinyi Xu, Hong Yao, 2020, European journal of medicinal chemistry.

Transition-metal-free and facile synthesis of 3-alkynylpyrrole-2, 4-dicarboxylates from methylene isocyanides and propiolaldehyde

Jiankang Zhang, Jiaan Shao, Huajian Zhu, 2021, New Journal of Chemistry.

Functionalized N-containing heterocyclic scaffolds derived from N-substituted pyrroles via inter- and intramolecular annulations

Shuaizhong Zhang, H. Zou, Huajian Zhu, 2018, Tetrahedron.

Metabolism guided optimization of peptidomimetics as non-covalent proteasome inhibitors for cancer treatment.

Yu-bo Zhou, Jia Li, Qian Yu, 2022, European journal of medicinal chemistry.

Effect of Naphthenic Acid and Metal Ions on Emulsification of Heavy Oil

Yinxiang Xu, Yiming Yan, Shenglan Liu, 2022, Energy & Fuels.

Design, synthesis and biological evaluation of novel tumor hypoxia-activated EGFR tyrosine kinase inhibitors.

Zongfu Pan, Jiankang Zhang, Jiaan Shao, 2022, Bioorganic chemistry.

Protein from Hylocereus polyrhizus protects MRC-5 cells against hydrogen peroxide (H2O2)-induced damage

Yue Zha, Sijia Zhou, Yuzhe Zhang, 2022, Food Science and Biotechnology.

"One-pot" cascade approach to 5,6-dihydroindolizines and indolizines from pyrrole-2-carbaldehydes and nitroethylenes

H. Zou, Huajian Zhu, Wenying Zhong, 2017 .

Interfacial Diffusion of Hydrated Ion on Graphene Surface: A Molecular Simulation Study.

Yinxiang Xu, Yishu Yan, Huajian Zhu, 2020, Langmuir : the ACS journal of surfaces and colloids.

Design, synthesis and biological evaluation of vinyl selenone derivatives as novel microtubule polymerization inhibitors.

Honghao Sun, Shengtao Xu, Jinyi Xu, 2020, European journal of medicinal chemistry.

Synthesis of isoquinolone via rhodium(III)-catalyzed C-H activation with 1,4,2-dioxazol-5-ones as oxidizing directing group

Jiankang Zhang, Rangxiao Zhuang, Huajian Zhu, 2019, Tetrahedron.

A facile chemoenzymatic approach: one-step syntheses of monoterpenoid indole alkaloids.

J. Stöckigt, Liuqing Yang, Liang Zhang, 2010, Chemistry, an Asian journal.

One-Pot NBS-Promoted Synthesis of Imidazoles and Thiazoles from Ethylarenes in Water

Hong Liu, Jiang Wang, Huajian Zhu, 2019, Molecules.

A facile approach to polysubstituted pyrazoles from hydrazonyl chlorides and vinyl azides

M. Giulianotti, Wenteng Chen, Yongping Yu, 2011 .

Sequential [3+2] annulation reaction of prop-2-ynylsulfonium salts and hydrazonyl chlorides: synthesis of pyrazoles containing functional motifs.

Shourong Liu, Jiankang Zhang, Jiaan Shao, 2021, Chemical communications.

"One-pot" multicomponent approach to indolizines and pyrido[1,2-a]indoles.

J. Stöckigt, Yongping Yu, H. Zou, 2011, Organic letters.

Cascade regioselective synthesis of pyrazoles from nitroallylic acetates and N-tosyl hydrazine

Qunxiong Zheng, H. Zou, Huajian Zhu, 2014 .

Functionalized heterocyclic scaffolds derived from Morita-Baylis-Hillman Acetates.

H. Zou, Huajian Zhu, Tong Chen, 2013, Chemical communications.

Methanol facilitated synthesis of 7-methoxy-2-thioxo-2,3-dihydro-1H-1,3-diazepin-4(7H)-ones from nitroallylic acetates and thiourea

Qunxiong Zheng, H. Zou, Huajian Zhu, 2014 .

Design and synthesis of NAD(P)H: Quinone oxidoreductase (NQO1)-activated prodrugs of 23-hydroxybetulinic acid with enhanced antitumor properties.

W. Ye, Shengtao Xu, Jinyi Xu, 2022, European journal of medicinal chemistry.

The reaction of prop-2-ynylsulfonium salts and sulfonyl-protected β-amino ketones to epoxide-fused 2-methylenepyrrolidines and S-containing pyrroles.

Jiankang Zhang, Jiaan Shao, Huajian Zhu, 2021, Chemical communications.

“One-Pot” Multicomponent Approach to Indolizines and Pyrido[1,2-a]indoles.

J. Stoeckigt, Yongping Yu, H. Zou, 2011 .

(2 + 1 + 1 + 1)-Annulation Reactions of Aryldiazonium Tetrafluoroborates with Sulfur Ylides to Polysubstituted Pyrazoles.

Jiankang Zhang, Jiaan Shao, Huajian Zhu, 2021, The Journal of organic chemistry.

Strictosidine Synthase Triggered Enantioselective Synthesis of N-Substituted (S)-3,14,18,19-Tetrahydroangustines as Novel Topoisomerase I Inhibitors.

A. Cherkasov, H. Zou, Huajian Zhu, 2017, ACS chemical biology.

Cu(II) Complexes with Proline-Derived Schiff Base Ligand: Chemical Resolution of N,C-Unprotected α-Amino Acids and Their Antibacterial Activity.

L. Lan, Hong Liu, Jiang Wang, 2022, The Journal of organic chemistry.

Discovery of a Novel Vascular Disrupting Agent Inhibiting Tubulin Polymerization and HDACs with Potent Antitumor Effects.

Dong-Hua Yang, Chenbang He, Zhe S Chen, 2022, Journal of medicinal chemistry.

Enantioselective Reduction of α,β-Unsaturated Ketones and Aryl Ketones by Perakine Reductase.

Sheng Cai, S. Zeng, Jinhao Zhao, 2019, Organic letters.

An update on the recent advances and discovery of novel tubulin colchicine binding inhibitors.

Jinyi Xu, Zheying Zhu, Huajian Zhu, 2023, Future medicinal chemistry.

Scaffold tailoring by a newly detected Pictet-Spenglerase activity of strictosidine synthase: from the common tryptoline skeleton to the rare piperazino-indole framework.

Artem Cherkasov, Meitian Wang, Hongbin Zou, 2012, Journal of the American Chemical Society.

Proteasome, a Promising Therapeutic Target for Multiple Diseases Beyond Cancer

Jiankang Zhang, Jiaan Shao, Rangxiao Zhuang, 2020, Drug design, development and therapy.

Using Strictosidine Synthase to Prepare Novel Alkaloids.

Meitian Wang, J. Stöckigt, Lianli Sun, 2014, Current medicinal chemistry.

Molecular Dynamics Simulation Reveals Unique Rheological and Viscosity–Temperature Properties of Karamay Heavy Crude Oil

X. Li, Yishu Yan, D. Ma, 2021 .

Stereocomplementary Chemoenzymatic Pictet–Spengler Reactions for Formation of Rare Azepino-indole Frameworks: Discovery of Antimalarial Compounds

S. Panjikar, Hujun Xie, H. Osada, 2019, ACS Catalysis.

Pd(II) Complexes of Chiral Proline-Derived Ligands: Application for Dynamic Thermodynamic Resolution of α-Amino Acids and Their Antibacterial Activities.

L. Lan, Hong Liu, Jiang Wang, 2023, The Journal of organic chemistry.

[Research progress on selective immunoproteasome inhibitors].

L. Kong, Huajian Zhu, Jingyi Lu, 2019, Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences.

Design, Synthesis and Antitumor Assessment of Phenylureas Bearing 5-Fluoroindolin-2-one Moiety.

H. Zou, Huajian Zhu, Tong Chen, 2020, Medicinal chemistry (Shariqah (United Arab Emirates)).

Recent advances and future perspectives of noncompetitive proteasome inhibitors.

Qian Yu, Jiaan Shao, Rangxiao Zhuang, 2023, Bioorganic chemistry.

Exploration of novel four-membered-heterocycle constructed peptidyl proteasome inhibitors with improved metabolic stability for cancer treatment.

G. Wei, Jia Li, Li-xin Gao, 2023, Bioorganic chemistry.

Molecular Simulations on Tuning the Interlayer Spacing of Graphene Nanoslits for C4H6/C4H10 Separation

Yinxiang Xu, Yiming Yan, Zhufeng Hu, 2021 .

Separation of 1-Butene and 2-Butene Isomers via Nanoporous Graphene: A Molecular Simulation Study

Yinxiang Xu, Huajian Zhu, Junbo Xu, 2020 .

Immunoproteasome-selective inhibitors: future of autoimmune diseases?

Jiaan Shao, Rangxiao Zhuang, Ruoyu He, 2020, Future medicinal chemistry.

Mechanism and Regulation of Spontaneous Water Transport in Graphene‐Based Nanoslits

Steven Wang, Huajian Zhu, Yuying Wang, 2018, Advanced Theory and Simulations.

Exploration of novel dihydroquinoxalinone derivatives as EGFRL858R/T790M tyrosine kinase inhibitors for the treatment of non-small-cell lung cancer.

Zongfu Pan, Shourong Liu, Jiaan Shao, 2023, Bioorganic chemistry.

Improved Expression of His6‐Tagged Strictosidine Synthase cDNA for Chemo‐Enzymatic Alkaloid Diversification

J. Stöckigt, Liuqing Yang, H. Zou, 2010, Chemistry and Biodiversity.

Discovery of novel hypoxia-activated, nitroimidazole constructed multi-target kinase inhibitors on the basis of AZD9291 for the treatment of human lung cancer.

Jiaan Shao, W. Cheng, Huajian Zhu, 2023, Bioorganic & Medicinal Chemistry.

Discovery of Norbornene as a Novel Hydrophobic Tag Applied in Protein Degradation.

Zhe-Sheng Chen, Dong-Hua Yang, Shengtao Xu, 2023, Angewandte Chemie.

Palladium-Catalyzed Synthesis of Polysubstituted Pyrazoles by Ring-Opening Reactions of 2H-Azirines with Hydrazones

Wenteng Chen, Huajian Zhu, Shuangrong Liu, 2020, Synlett.

Privileged biorenewable secologanin-based diversity-oriented synthesis for pseudo-natural alkaloids: uncovering novel neuroprotective and antimalarial frameworks.

H. Osada, Y. Futamura, H. Zou, 2021, ChemSusChem.