K. Nakata

发表

A novel tamoxifen derivative, ridaifen-F, is a nonpeptidic small-molecule proteasome inhibitor.

T. Kunoh, T. Mizukami, M. Shionyu, 2014, European journal of medicinal chemistry.

Non-enzymatic dynamic kinetic resolution of racemic α-arylalkanoic acids: an advanced asymmetric synthesis of chiral nonsteroidal anti-inflammatory drugs (NSAIDs)

Isamu Shiina, K. Nakata, K. Ono, 2012 .

Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement.

M. Ikekita, S. Dan, Y. Nagahara, 2013, Biochemical and biophysical research communications.

Novel Ridaifen-B Structure Analog Induces Apoptosis and Autophagy Depending on Pyrrolidine Side Chain.

Y. Nagahara, T. Shinomiya, Isamu Shiina, 2019, Biological & pharmaceutical bulletin.

Induction of mitochondria‐involved apoptosis in estrogen receptor‐negative cells by a novel tamoxifen derivative, ridaifen‐B

M. Ikekita, Y. Nagahara, Akane Sasaki, 2008, Cancer science.

Medium‐Sized Lactones

Isamu Shiina, K. Nakata, Kenya Nakata, 2013 .

Acceleration of CuI-catalyzed coupling reaction of alkyl halides with aryl Grignard reagents using lithium chloride

Yuichi Kobayashi, C. Feng, Toshifumi Tojo, 2014 .

Asymmetric epoxidation with a photoactivated [Ru(salen)] complex.

T. Katsuki, J. Mihara, R. Irie, 2001, Chemistry.

Kinetic Resolution of Racemic Secondary Benzylic Alcohols by the Enantioselective Esterification Using Pyridine‐3‐carboxylic Anhydride (3‐PCA) with Chiral Acyl‐Transfer Catalysts

Isamu Shiina, T. Mukaiyama, K. Nakata, 2012 .

4-(Dimethylamino)pyridine N-oxide (DMAPO): an effective nucleophilic catalyst in the peptide coupling reaction with 2-methyl-6-nitrobenzoic anhydride.

Isamu Shiina, K. Nakata, H. Ushiyama, 2008, Chemistry, an Asian journal.

Synthesis and reactivity of (1-fluorovinyl) phenyl sulfoxide as a dienophile

T. Hanamoto, M. Kondo, Y. Koga, 2002 .

An expeditious synthesis of tamoxifen, a representative SERM (selective estrogen receptor modulator), via the three-component coupling reaction among aromatic aldehyde, cinnamyltrimethylsilane, and beta-chlorophenetole.

M. Ikekita, Y. Nagahara, Akane Sasaki, 2007, Bioorganic & medicinal chemistry.

Lewis Acid‐Catalyzed Nucleophilic Substitutions of Benzylic Alcohols with Sulfamides

K. Nakata, R. Oda, Kenya Nakata, 2020 .

Chemodivergent Dehydrative Nucleophilic Substitutions of Diarylmethanols with 1‐Phenyl‐1 H ‐tetrazole‐5‐thiol Catalyzed by FeCl 3

K. Nakata, R. Oda, 2020 .

Diastereoconvergent Dehydrative Nucleophilic Substitutions of Diastereomeric Diarylmethanols with 1,3-Dicarbonyls Catalyzed by SnBr4

Hiroshi M Yamamoto, K. Nakata, Rikiya Kubo, 2019 .

Diastereoconvergent Synthesis of Chiral Diarylmethyl Sulfones by Direct Sulfonylation of Diarylmethanols Diastereomixtures with Sodium Sulfinates Catalyzed by SnBr2

Hiroshi M Yamamoto, K. Nakata, H. Yamamoto, 2019, European Journal of Organic Chemistry.

Chiral-Auxiliary-Controlled Diastereoconvergent Benzamidation Reactions of Diastereomixtures of Diarylmethanols with Benzamide Catalyzed by SnBr4

K. Nakata, Rikiya Kubo, 2019, Asian Journal of Organic Chemistry.

Stereoconvergent Chiral Inductive Diastereodivergent Sulfonamidation of Diastereomixtures of Diarylmethanols with Sulfonylamine Catalyzed by Lewis Acids.

Hiroshi M Yamamoto, K. Nakata, H. Yamamoto, 2018, Organic letters.

Chiral Inductive Diastereoconvergent Friedel–Crafts Alkylation Reaction of Diastereomixtures of Diarylmethanols with 2‐Naphthol Derivatives Catalyzed by SnBr4

K. Nakata, Nobuharu Suzuki, 2017 .

SnBr4-promoted Friedel–Crafts type dehydrative alkylation reaction of diarylmethanols with 2-naphthol derivatives

K. Nakata, Nobuharu Suzuki, Shiori Tsuchihashi, 2016 .

InCl3-promoted intramolecular decarboxylative etherification of benzylic carbonates

K. Nakata, Tatsuya Tokumaru, Kenya Nakata, 2015 .

Silylative Kinetic Resolution of Racemic 2,2‐Dialkyl 5‐ and 6‐Membered Cyclic Benzylic Alcohol Derivatives Catalyzed by Chiral Guanidine, ( R )‐ N ‐Methylbenzoguanidine

K. Nakata, Shuhei Yoshimatsu, 2019, Advanced Synthesis & Catalysis.

Chiral Inductive Diastereoconvergent Allylation Reactions of Allyltrimethylsilane and Diastereomixtures of Diarylmethanols Catalyzed by FeCl3

K. Nakata, Rina Fujihara, 2018, European Journal of Organic Chemistry.

Reformatsky Reagent Promoted Acetylation of Primary and Secondary Aliphatic Alcohols Using Ethyl Acetate as an Acetyl Donor

K. Nakata, Rina Fujihara, 2019, ChemistrySelect.

Chemoselective N-acetylation of primary aliphatic amines promoted by pivalic or acetic acid using ethyl acetate as an acetyl donor

Tomoki Yoshida, K. Nakata, Shimpei Kawamura, 2017 .

(R)-(+)-N-methylbenzoguanidine ((R)-NMBG) catalyzed kinetic resolution of racemic secondary benzylic alcohols with free carboxylic acids by asymmetric esterification.

Isamu Shiina, K. Nakata, 2011, Organic & biomolecular chemistry.

Synthesis of Lasofoxifene, Nafoxidine and Their Positional Isomers via the Novel Three-Component Coupling Reaction

Isamu Shiina, K. Nakata, Y. Sano, 2010, Molecules.

Kinetic resolution of racemic 2-hydroxy-γ-butyrolactones by asymmetric esterification using diphenylacetic acid with pivalic anhydride and a chiral acyl-transfer catalyst.

Isamu Shiina, K. Nakata, K. Ono, 2013, Organic letters.

Kinetic resolution of racemic alpha-arylalkanoic acids with achiral alcohols via the asymmetric esterification using carboxylic anhydrides and acyl-transfer catalysts.

Y. Onda, Isamu Shiina, K. Nakata, 2010, Journal of the American Chemical Society.

Kinetic Resolution of Racemic Carboxylic Acids Using Achiral Alcohols by the Promotion of Benzoic Anhydrides and Tetramisole Derivatives: Production of Chiral Nonsteroidal Anti-Inflammatory Drugs and Their Esters

Y. Onda, Isamu Shiina, K. Nakata, 2008 .

Design and Synthesis of Axial‐Chirality‐Containing Guanidine Catalysts

T. Ikeue, K. Nakata, Manaya Iwakura, 2022, ChemistrySelect.

Two-Step Kinetic Resolution of Racemic Secondary Benzylic Alcohols Using the Combination of Enantioselective Silylation and Acylation: One-Pot Procedure Catalyzed by Chiral Guanidine.

K. Nakata, Kanako Miyazaki, Kenya Nakata, 2022, The Journal of organic chemistry.

Kinetic Resolution of Racemic 2‐Hydroxyarylketones by Asymmetric Esterification: Investigation of the Influence of the Co‐Base on the Selectivity

Isamu Shiina, K. Nakata, K. Ono, 2020 .

Acylative Kinetic Resolution of Racemic 2,2‐Dimethyl‐Substituted Nitroaldol (Henry) Adducts Using a Chiral Guanidine Catalyst: ( R )‐(+)‐ N ‐Methylbenzoguanidine (( R )‐NMBG)

R. Kishida, K. Nakata, T. Ichimura, 2019, ChemistrySelect.

Acylative kinetic resolution of racemic aromatic β-hydroxy esters catalyzed by chiral nucleophilic N-(1-arylethyl)benzoguanidines

Isamu Shiina, K. Nakata, A. Yamada, 2017 .

(R)-(+)-N-Methylbenzoguanidine ((R)-NMBG) catalyzed acylative kinetic resolution of racemic 3-hydroxy-3-aryl-propanoates

K. Nakata, A. Yamada, Kenya Nakata, 2016 .

Kinetic Resolution of Racemic 1-Heteroarylalkanols by Asymmetric Esterification Using Diphenylacetic Acid with Pivalic Anhydride and a Chiral Acyl-transfer Catalyst

Isamu Shiina, K. Nakata, K. Ono, 2011 .

An effective kinetic resolution of racemic α-arylpropanoic acids, α-arylbutanoic acids, and β-substituted-α-arylpropanoic acids with bis(9-phenanthryl)methanol as a new achiral nucleophile in the asymmetric esterification using carboxylic anhydrides and the acyl-transfer catalyst

Isamu Shiina, K. Nakata, K. Ono, 2010 .

Kinetic resolution of the racemic 2-hydroxyalkanoates using the enantioselective mixed-anhydride method with pivalic anhydride and a chiral acyl-transfer catalyst.

Isamu Shiina, K. Nakata, K. Ono, 2010, Chemistry.

An effective kinetic resolution of racemic secondary benzylic alcohols using 3-pyridinecarboxylic anhydride and a chiral acyl-transfer catalyst in the absence of tertiary amine

Isamu Shiina, K. Nakata, 2010 .

2,2-DISUBSTITUTED PROPIONIC ANHYDRIDES : EFFECTIVE COUPLING REAGENTS FOR THE KINETIC RESOLUTION OF SECONDARY BENZYLIC ALCOHOLS USING BTM

Y. Onda, Isamu Shiina, K. Nakata, 2009 .

The first asymmetric esterification of free carboxylic acids with racemic alcohols using benzoic anhydrides and tetramisole derivatives: an application to the kinetic resolution of secondary benzylic alcohols

Isamu Shiina, K. Nakata, Kenya Nakata, 2007 .

Kinetic Resolution of Racemic 2-Hydroxyamides Using a Diphenylacetyl Component as an Acyl Source and a Chiral Acyl-Transfer Catalyst

Isamu Shiina, K. Nakata, K. Ono, 2018, Molecules.

A new method for production of chiral 2-aryloxypropanoic acids using effective kinetic resolution of racemic 2-aryloxycarboxylic acids

Isamu Shiina, K. Nakata, K. Ono, 2012 .

New reagent system for attaining high regio- and stereoselectivities in allylic displacement of 4-cyclopentene-1,3-diol monoacetate with aryl- and alkenylmagnesium bromides.

Yuichi Kobayashi, K. Nakata, Takayuki Ainai, 2005, Organic letters.

Aryl- and alkenyllithium preparations and copper-catalyzed reaction between the derived magnesium reagents and the monoacetate of 4-cyclopentene-1,3-diol.

Yuichi Kobayashi, K. Nakata, 2005, Organic letters.

(Salen)ruthenium-Catalyzed Desymmetrization of Meso-Diols: Catalytic Aerobic Asymmetric Oxidation under Photo-Irradiation

T. Katsuki, K. Nakata, Hideki Shimizu, 2002 .

An Enantiodivergent Synthesis of (+)‐ and (−)‐Centrolobines by Asymmetric Esterification Catalyzed by (R)‐(+)‐N‐Methylbenzoguanidine ((R)‐NMBG)

Isamu Shiina, H. Iwamoto, K. Nakata, 2013 .

A convenient method for the kinetic resolution of racemic 2-hydroxyalkanoates using diphenylacetic anhydride (DPHAA) and a chiral acyl-transfer catalyst

Isamu Shiina, K. Nakata, Akihiro Sekiguchi, 2011 .

[Development of novel methods for preparing chiral non-steroidal anti-inflammatory drugs (NSAIDs) by asymmetric esterification].

K. Nakata, 2012, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Synthesis of the new pseudo-symmetrical tamoxifen derivatives and their anti-tumor activity.

M. Ikekita, Akane Sasaki, Isamu Shiina, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and pharmacological evaluation of the novel pseudo-symmetrical tamoxifen derivatives as anti-tumor agents.

M. Ikekita, Y. Nagahara, T. Yamori, 2008, Biochemical pharmacology.

Highly Efficient Silylative Kinetic Resolution of Racemic trans ‐2‐Alkyl‐1‐indanols Catalyzed by Chiral Guanidine

K. Nakata, Takeshi Suzuki, Manaya Iwakura, 2021, ChemistrySelect.

Chiral Guanidine Catalyzed Acylative Kinetic Resolution of Racemic 2-Bromo-1-arylethanols

K. Nakata, Eri Sawada, 2020 .

Silylative Kinetic Resolution of Racemic 1-Indanol Derivatives Catalyzed by Chiral Guanidine.

K. Nakata, Shuhei Yoshimatsu, A. Yamada, 2018, The Journal of organic chemistry.