Sawako Shimizu

Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262.

Koichi M Iijima, Taro Saito, A. Asada, 2019, Human molecular genetics.

Microtubule affinity–regulating kinase 4 with an Alzheimer's disease-related mutation promotes tau accumulation and exacerbates neurodegeneration

Koichi M Iijima, Taro Saito, A. Asada, 2020, The Journal of Biological Chemistry.

Ca2+/calmodulin-dependent protein kinase II promotes neurodegeneration caused by tau phosphorylated at Ser262/356 in a transgenic Drosophila model of tauopathy

Taro Saito, S. Hisanaga, K. Ando, 2017, Journal of biochemistry.

Tau phosphorylation at Alzheimer's disease-related Ser356 contributes to tau stabilization when PAR-1/MARK activity is elevated.

S. Hisanaga, K. Ando, Y. Ohtake, 2016, Biochemical and biophysical research communications.

S6K/p70S6K1 protects against tau-mediated neurodegeneration by decreasing the level of tau phosphorylated at Ser262 in a Drosophila model of tauopathy

Taro Saito, S. Hisanaga, A. Asada, 2018, Neurobiology of Aging.

MARK4 with an Alzheimer’s disease-related mutation promotes tau hyperphosphorylation directly and indirectly and exacerbates neurodegeneration

Taro Saito, A. Asada, K. Ando, 2020, bioRxiv.