Dolores Diaz

Rhizoctonia solani fucomannogalactan: Chemical characterization and antiproliferative activity.

A. Prieto, M. D. L. Corradi da Silva, R. Kaneno, 2018, International journal of biological macromolecules.

Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease

Nicholas E. Propson, R. Maciuca, K. Scearce-Levie, 2022, Science Translational Medicine.

Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

Katrina W. Lexa, B. Boeve, H. Rosen, 2021, Cell.

Molecular architecture determines brain delivery of a transferrin receptor–targeted lysosomal enzyme

K. Scearce-Levie, K. Gunasekaran, L. Shan, 2021, bioRxiv.

Characterization of Fluid Biomarkers Reveals Lysosome Dysfunction and Neurodegeneration in Neuronopathic MPS II Patients

K. Scearce-Levie, G. Astarita, M. Troyer, 2020, International journal of molecular sciences.

Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice

Adam P. Silverman, Jennifer A. Getz, Michelle L. Reyzer, 2020, Science Translational Medicine.

Iduronate-2-sulfatase transport vehicle rescues behavioral and skeletal phenotypes in a mouse model of Hunter syndrome

T. Gill, K. Scearce-Levie, Elliot R. Thomsen, 2021, JCI insight.

LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's Disease

R. Maciuca, K. Scearce-Levie, D. Jennings, 2023, Movement disorders : official journal of the Movement Disorder Society.

A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models

Nicholas E. Propson, K. Scearce-Levie, Steve Lianoglou, 2023, Nature Neuroscience.