Elena V. Knatko

发表

Nrf2 activation does not affect adenoma development in a mouse model of colorectal cancer

J. Griffin, C. Wolf, Ying Zhang, 2021, Communications Biology.

Downregulation of Keap1 Confers Features of a Fasted Metabolic State

M. Tatham, J. Griffin, R. Hay, 2020, iScience.

University of Dundee Loss of Nrf 2 abrogates the protective effect of Keap 1 down regulation in a preclinical model of cutaneous squamous cell carcinoma

A. Dinkova-Kostova, J. Fahey, M. Higgins, 2016 .

Nrf2 Activation Protects against Solar-Simulated Ultraviolet Radiation in Mice and Humans

S. Ibbotson, C. Proby, Ying Zhang, 2015, Cancer Prevention Research.

Nrf 2 Activation Protects against Solar-Simulated Ultraviolet Radiation in Mice and Humans

S. Ibbotson, C. Proby, Ying Zhang, 2015 .

Transcription factors NRF2 and HSF1 have opposing functions in autophagy

G. Ball, A. Dinkova-Kostova, S. Dayalan Naidu, 2017, Scientific Reports.

SINHCAF/FAM60A links SIN3A function to the hypoxia response and its levels are predictive of cancer patient survival

T. Owen-Hughes, S. Rocha, D. Bandarra, 2017, bioRxiv.

The indirect antioxidant sulforaphane protects against thiopurine-mediated photooxidative stress.

A. Dinkova-Kostova, Elena V. Knatko, Andrea L. Benedict, 2012, Carcinogenesis.

Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response

A. Lamond, J. Arthur, D. Cantrell, 2022, iScience.

Highly Potent Activation of Nrf2 by Topical Tricyclic Bis(Cyano Enone): Implications for Protection against UV Radiation during Thiopurine Therapy

Masayuki Yamamoto, Ying Zhang, A. Dinkova-Kostova, 2012, Cancer Prevention Research.

Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity

J. Hiscott, Sharadha Dayalan Naidu, A. Dinkova-Kostova, 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Edward T Chouchani, John Szpyt, Mark P. Jedrychowski, 2018, Nature.

Mitotic mechanics: the auroras come into view.

J. Swedlow, W. Moore, P. D. Andrews, 2003, Current opinion in cell biology.

Clinically relevant aberrant Filip1l DNA methylation detected in a murine model of cutaneous squamous cell carcinoma

C. Proby, A. Dinkova-Kostova, S. Steyaert, 2021, EBioMedicine.

Pirin, an Nrf2-Regulated Protein, Is Overexpressed in Human Colorectal Tumors

Gillian Smith, Ying Zhang, A. Dinkova-Kostova, 2022, Antioxidants.

Loss of Nrf2 abrogates the protective effect of Keap1 downregulation in a preclinical model of cutaneous squamous cell carcinoma

A. Dinkova-Kostova, J. Fahey, M. Higgins, 2016, Scientific Reports.

A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia.

S. Denis, R. Houtkooper, E. Lutgens, 2018, Cell reports.

Nrf2 is a central regulator of the metabolic landscape in macrophages and finetunes their inflammatory response

A. Lamond, D. Cantrell, Sharadha Dayalan Naidu, 2021, bioRxiv.

Essential functions of Sds22p in chromosome stability and nuclear localization of PP1.

A. Bloecher, M. Peggie, M. Stark, 2002, Journal of cell science.

Summary Essential functions of Sds 22 p in chromosome stability and nuclear localization of PP 1

A. Bloecher, M. Peggie, M. Stark, 2001 .

Functional mapping of the fission yeast DNA polymerase δ B-subunit Cdc1 by site-directed and random pentapeptide insertion mutagenesis

T. Tahirov, S. MacNeill, F. C. Gray, 2009, BMC Molecular Biology.

Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action

A. Dinkova-Kostova, T. Honda, Suqing Zheng, 2015, Biochemical and biophysical research communications.

Oral Azathioprine Leads to Higher Incorporation of 6-Thioguanine in DNA of Skin than Liver: The Protective Role of the Keap1/Nrf2/ARE Pathway

Masayuki Yamamoto, Ying Zhang, A. Dinkova-Kostova, 2011, Cancer Prevention Research.

Transcription factors NRF2 and HSF1 have opposing functions in autophagy

G. Ball, A. Dinkova-Kostova, S. Dayalan Naidu, 2017, Scientific Reports.

Whole-Exome Sequencing Validates a Preclinical Mouse Model for the Prevention and Treatment of Cutaneous Squamous Cell Carcinoma

C. Proby, K. Purdie, A. Dinkova-Kostova, 2016, Cancer Prevention Research.

The isoquinoline PRL-295 increases the thermostability of Keap1 and disrupts its interaction with Nrf2

Takafumi Suzuki, Masayuki Yamamoto, Sharadha Dayalan Naidu, 2021, iScience.

Nrf2 depletion in the context of loss-of-function Keap1 leads to mitolysosome accumulation.

A. Dinkova-Kostova, L. de la Vega, I. Ganley, 2023, Free radical biology & medicine.

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

John Szpyt, Mark P. Jedrychowski, R. Fischer, 2018, Nature.

Highly Potent Activation of Nrf2 by Topical Tricyclic Bis(Cyano Enone): Implications for Protection against UV Radiation during Thiopurine Therapy

Masayuki Yamamoto, Ying Zhang, A. Dinkova-Kostova, 2012, Cancer Prevention Research.

Functional mapping of the fission yeast DNA polymerase δ B-subunit Cdc1 by site-directed and random pentapeptide insertion mutagenesis

T. Tahirov, S. MacNeill, F. C. Gray, 2009, BMC Molecular Biology.