Xiaohui Hu

发表

Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors.

W. Zhou, K. Tam, Wen Zhang, 2018, Journal of proteome research.

Quantification of permanent positively charged compounds in plasma using one-step dilution to reduce matrix effect in MS.

W. Zhou, K. Tam, Xiaohui Hu, 2016, Bioanalysis.

Significance of the detection of TIM-3 and FOXJ1 in prostate cancer.

W. Yuan, Y. Lan, Xiaohui Hu, 2017, Journal of B.U.ON. : official journal of the Balkan Union of Oncology.

Association of Vancomycin with Lipid Vesicles

K. Tam, Xiaohui Hu, 2017, bioRxiv.

Phenyl butyrate inhibits pyruvate dehydrogenase kinase 1 and contributes to its anti‐cancer effect

K. Tam, Wen Zhang, Xiaohui Hu, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Anticancer effects of some novel dichloroacetophenones through the inhibition of pyruvate dehydrogenase kinase 1

K. Tam, Xiaohui Hu, Shao-Lin Zhang, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Transcription in fungal conidia before dormancy produces phenotypically variable conidia that maximize survival in different environments

Yingying Chen, K. H. Wong, Kaeling Tan, 2021, Nature Microbiology.

Targeting Tumor Metabolism for Cancer Treatment: Is Pyruvate Dehydrogenase Kinases (PDKs) a Viable Anticancer Target?

K. Tam, Wen Zhang, Xiaohui Hu, 2015, International journal of biological sciences.

Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics.

K. Tam, Wen Zhang, Xiaohui Hu, 2018, ACS combinatorial science.

Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti‐cancer effect of EGFR tyrosine kinase inhibitors in non‐small cell lung cancer

K. Tam, Xiaohui Hu, Shao-Lin Zhang, 2018, European journal of pharmacology.

Development of pyruvate dehydrogenase kinase inhibitors in medicinal chemistry with particular emphasis as anticancer agents.

K. Tam, Wen Zhang, Xiaohui Hu, 2015, Drug discovery today.

Synthesis and biological evaluation of (R)‐3,3,3‐trifluoro‐2‐hydroxy‐2‐methylpropionamides as pyruvate dehydrogenase kinase 1 (PDK1) inhibitors to reduce the growth of cancer cells

K. Tam, Wen Zhang, Xiaohui Hu, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Combined use of arginase and dichloroacetate exhibits anti‐proliferative effects in triple negative breast cancer cells

Y. Leung, K. Tam, Xiaohui Hu, 2018, The Journal of pharmacy and pharmacology.

Biomembrane mimics and their roles in anti-bacterial drug discovery

K. Tam, Xiaohui Hu, 2017 .

Simultaneous Treatment of Renal and Upper Ureteral Stone and Cysts With Percutaneous Nephrolithotomy and Cyst Laser Intrarenal Incision and Drainage.

Xiaohui Hu, Kehua Jiang, Hongbo Chen, 2018, Urology journal.

Development of dichloroacetamide pyrimidines as pyruvate dehydrogenase kinase inhibitors to reduce cancer cell growth: synthesis and biological evaluation

Zhiyi Wei, K. Tam, Wen Zhang, 2016 .

Cytoskeleton Molecular Motors: Structures and Their Functions in Neuron

Zhiyi Wei, K. Tam, Xiaohui Hu, 2016, International journal of biological sciences.

Unexpected Discovery of Dichloroacetate Derived Adenosine Triphosphate Competitors Targeting Pyruvate Dehydrogenase Kinase To Inhibit Cancer Proliferation.

K. Tam, Wen Zhang, Xiaohui Hu, 2016, Journal of medicinal chemistry.

Systemic clearance and brain distribution of carbazole-based cyanine compounds as Alzheimer’s disease drug candidates

K. Tam, Wei Zhou, Xiaohui Hu, 2017, Scientific Reports.

Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships.

K. Tam, Xiaohui Hu, Shao-Lin Zhang, 2018, Bioorganic & medicinal chemistry letters.