A. Borroto

发表

CD3ε recruits Numb to promote TCR degradation.

I. Screpanti, N. Martín-Blanco, B. Alarcón, 2016, International immunology.

Protein ectodomain shedding.

J. Arribas, A. Borroto, 2002, Chemical reviews.

Antigen presentation between T cells drives Th17 polarization under conditions of limiting antigen

Manuel D. Díaz-Muñoz, E. R. Bovolenta, C. Oeste, 2020, Cell reports.

Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses

F. Sánchez‐Madrid, B. Alarcón, G. Ramírez-Santiago, 2017, Nature Communications.

All-or-none downregulation of the T cell antigen receptor

A. Alcover, C. Terhorst, D. Gutiérrez, 2001 .

Conformational changes in the T cell receptor differentially determine T cell subset development in mice

P. Pereira, R. Blanco, W. Schamel, 2014, Science Signaling.

The CD3 epsilon subunit of the TCR contains endocytosis signals.

B. Alarcón, A. Dautry‐Varsat, A. Alcover, 1999, Journal of immunology.

Characterization of the Region Involved in CD3 Pairwise Interactions within the T Cell Receptor Complex*

A. Mallabiabarrena, C. Martínez-A, B. Alarcón, 1998, The Journal of Biological Chemistry.

Relevance of Nck–CD3ε Interaction for T Cell Activation In Vivo

A. Órfão, R. Blanco, W. Schamel, 2014, The Journal of Immunology.

Nck Recruitment to the TCR Required for ZAP70 Activation during Thymic Development

A. Órfão, W. Schamel, B. Alarcón, 2013, The Journal of Immunology.

First-in-class inhibitor of the T cell receptor for the treatment of autoimmune diseases

P. Bovolenta, Pilar Martín, A. Órfão, 2016, Science Translational Medicine.

The CD3ε Subunit of the TCR Contains Endocytosis Signals

B. Alarcón, A. Dautry‐Varsat, A. Alcover, 1999, The Journal of Immunology.

Aurora A drives early signalling and vesicle dynamics during T-cell activation

M. Malumbres, F. Sánchez‐Madrid, J. Vázquez, 2016, Nature Communications.

Construction of Retroviral Vectors Carrying Human CD3γ cDNA and Reconstitution of CD3γ Expression and T Cell Receptor Surface Expression and Function in a CD3γ-Deficient Mutant T Cell Line

B. Alarcón, J. R. Regueiro, A. Pacheco-Castro, 1997 .

Recycling of Cell Surface Pro-transforming Growth Factor-α Regulates Epidermal Growth Factor Receptor Activation*

J. Arribas, J. Bech-Serra, A. Borroto, 2005, Journal of Biological Chemistry.

A non-conserved amino acid variant regulates differential signalling between human and mouse CD28

I. Screpanti, Martina Kunkl, L. Tuosto, 2018, Nature Communications.

A Cholesterol-Based Allostery Model of T Cell Receptor Phosphorylation.

T. Höfer, N. Martín-Blanco, R. Blanco, 2016, Immunity.

SFRP1 modulates astrocyte‐to‐microglia crosstalk in acute and chronic neuroinflammation

P. Bovolenta, M. Heneka, B. Alarcón, 2021, EMBO reports.

SFRP1 shapes astrocyte to microglia cross-talk in acute and chronic neuroinflammation

P. Bovolenta, M. Heneka, B. Alarcón, 2020, bioRxiv.

Astrocyte to microglia cross-talk in acute and chronic neuroinflammation is shaped by SFRP1

P. Bovolenta, M. Heneka, B. Alarcón, 2020 .

Transferrin receptor induces tyrosine phosphorylation in T cells and is physically associated with the TCR zeta-chain.

M. Crumpton, B. Alarcón, M. Fresno, 1995, Journal of immunology.

Triggering the TCR complex causes the downregulation of nonengaged receptors by a signal transduction-dependent mechanism.

B. Alarcón, A. Alcover, F. Niedergang, 2000, Immunity.

The carboxy-terminal cysteine of the tetraspanin L6 antigen is required for its interaction with SITAC, a novel PDZ protein.

J. Baselga, J. Arribas, F. Rojo, 2000, Molecular biology of the cell.

Rho regulates T cell receptor ITAM‐induced lymphocyte spreading in an integrin‐independent manner

F. Sánchez‐Madrid, B. Alarcón, A. Alcover, 2000, European journal of immunology.

Impaired Trafficking and Activation of Tumor Necrosis Factor-α-converting Enzyme in Cell Mutants Defective in Protein Ectodomain Shedding*

C. Blobel, J. Baselga, A. Pandiella, 2003, Journal of Biological Chemistry.

Crammed signaling motifs in the T-cell receptor.

B. Alarcón, D. Abia, A. Borroto, 2014, Immunology letters.

Interaction between the N-terminal SH3 domain of Nck-alpha and CD3-epsilon-derived peptides: non-canonical and canonical recognition motifs.

B. Alarcón, M. Jiménez, M. Rico, 2009, Biochimica et biophysica acta.

IMMUNITY AND PROTECTION ELICITED BY a RECOMBINANT VACCINE AGAINST ENTEROTOXIGENIC E. Coli

J. Fuente, A. Borroto, Roberto Basulto, 1995 .

Protein Ectodomain Shedding

J. Arribas, A. Borroto, 2003 .

Small molecule AX-024 targets T cell receptor signaling by disrupting CD3ε-Nck interaction

B. Alarcón, A. Borroto, 2020, Journal of Biological Chemistry.

A non-conserved amino acid variant regulates differential signalling between human and mouse CD28

I. Screpanti, Martina Kunkl, L. Tuosto, 2018, Nature Communications.

Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses

F. Sánchez‐Madrid, B. Alarcón, E. Veiga, 2017, Nature Communications.

Construction of retroviral vectors carrying human CD3 gamma cDNA and reconstitution of CD3 gamma expression and T cell receptor surface expression and function in a CD3 gamma-deficient mutant T cell line.

B. Alarcón, J. R. Regueiro, A. Pacheco-Castro, 1997, Human gene therapy.

Dynamic reorganisation of intermediate filaments coordinates early B-cell activation

A. Bruckbauer, B. Alarcón, F. Batista, 2018, Life Science Alliance.