T. Dorn

发表

Progressive stretch enhances growth and maturation of 3D stem-cell-derived myocardium

Xiaochun Cao-Ehlker, A. M. Batcha, T. Seidel, 2021, Theranostics.

Treatment of Patients with Long-QT Syndrome: Differentiation of Patient-Derived Induced Pluripotent Stem Cells into Functional Cardiac Myocytes

D. Sinnecker, K. Laugwitz, R. Dirschinger, 2013 .

Modeling Long-QT Syndromes with iPS Cells

D. Sinnecker, K. Laugwitz, R. Dirschinger, 2013, Journal of Cardiovascular Translational Research.

Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors

M. Krane, G. Cuda, M. Gaspari, 2022, Nature Cell Biology.

Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia

Laura Iop, Peter Lipp, Thomas Gudermann, 2012, EMBO molecular medicine.

Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes

C. Mummery, P. Lipp, D. Sinnecker, 2016, European heart journal.

High-throughput optical action potential recordings in hiPSC-derived cardiomyocytes with a genetically encoded voltage indicator in the AAVS1 locus

P. Lipp, D. Sinnecker, K. Laugwitz, 2022, Frontiers in Cell and Developmental Biology.

Generation of heterozygous (MRli003-A-3) and homozygous (MRli003-A-4) TRPM4 knockout human iPSC lines.

P. Lipp, K. Laugwitz, A. Moretti, 2022, Stem cell research.

Generation of heterozygous (MRli003-A-1) and homozygous (MRli003-A-2) MYH10 knockout human iPSC lines.

K. Laugwitz, A. Moretti, T. Dorn, 2021, Stem cell research.

Pluripotent stem cell models of human heart disease.

C. Mummery, D. Sinnecker, K. Laugwitz, 2013, Cold Spring Harbor perspectives in medicine.

Retinoic acid signaling modulation guides in vitro specification of human heart field-specific progenitor pools

R. Pedersen, K. Laugwitz, Daniel Ortmann, 2022, bioRxiv.

Patient-specific induced pluripotent stem-cell models for long-QT syndrome.

Karl-Ludwig Laugwitz, Franz Hofmann, Milena Bellin, 2010, New England Journal of Medicine.

The Wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis

Astrid S. Pfister, M. Kühl, K. Laugwitz, 2019, Developmental biology.

Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy

E. Wolf, H. Blum, W. Wurst, 2020, Nature Medicine.

RhoH is important for positive thymocyte selection and T-cell receptor signaling.

M. Sixt, J. Ellwart, B. Holzmann, 2007, Blood.

Analysis of RhoH function in vivo

T. Dorn, Tatjana Dorn, 2007 .

MicroRNA-365 regulates human cardiac action potential duration

T. Meitinger, M. Borggrefe, M. Biel, 2022, Nature Communications.

EBF2 regulates osteoblast-dependent differentiation of osteoclasts.

Rudolf Grosschedl, R. Grosschedl, Gergana Dobreva, 2005, Developmental cell.

Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy

E. Wolf, H. Blum, W. Wurst, 2020, Nature Medicine.

Precise Correction of Heterozygous SHOX2 Mutations in hiPSCs Derived from Patients with Atrial Fibrillation via Genome Editing and Sib Selection

A. Jauch, G. Rappold, S. Kääb, 2020, Stem cell reports.

Interplay of cell–cell contacts and RhoA/MRTF‐A signaling regulates cardiomyocyte identity

L. Iop, T. Meitinger, Austin G Smith, 2018, The EMBO journal.

Epicardioid single-cell genomics uncovers principles of human epicardium biology in heart development and disease

Laura D. Martens, J. Gagneur, P. Lipp, 2023, Nature Biotechnology.

Sequential Defects in Cardiac Lineage Commitment and Maturation Cause Hypoplastic Left Heart Syndrome

R. Lange, M. Mann, T. Meitinger, 2021, bioRxiv.

Direct Nkx2‐5 Transcriptional Repression of Isl1 Controls Cardiomyocyte Subtype Identity

P. Lipp, M. Kühl, D. Sinnecker, 2015, Stem cells.

Primate heart regeneration via migration and fibroblast repulsion by human heart progenitors

M. Krane, G. Cuda, M. Gaspari, 2020, bioRxiv.

Human Induced Pluripotent Stem Cells as Platform for Functional Examination of Cardiovascular Genetics in a Dish

R. Dirschinger, A. Moretti, T. Dorn, 2019, Genetic Causes of Cardiac Disease.

Deciphering the Role of Wnt and Rho Signaling Pathway in iPSC-Derived ARVC Cardiomyocytes by In Silico Mathematical Modeling

C. Cosentino, F. Montefusco, G. Cuda, 2021, International journal of molecular sciences.

Recapitulating porcine cardiac development in vitro: from expanded potential stem cell to embryo culture models

K. Laugwitz, A. Bähr, C. Kupatt, 2023, Frontiers in Cell and Developmental Biology.

Rhoh deficiency reduces peripheral T‐cell function and attenuates allogenic transplant rejection

É. Kiss, H. Gröne, C. Brakebusch, 2011, European journal of immunology.

Generation of two human iPSC lines, HMGUi003-A and MRIi028-A, carrying pathogenic biallelic variants in the PPCS gene.

Y. Anikster, K. Laugwitz, Ejona Rusha, 2022, Stem cell research.

Patient-specific induced pluripotent stem-cell models for long-QT syndrome.

M. Seyfarth, A. Schömig, F. Hofmann, 2010 .

MicroRNA-365 regulates human cardiac action potential duration

T. Meitinger, M. Borggrefe, M. Biel, 2022, Nature communications.

Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes.

C. Mummery, P. Lipp, D. Sinnecker, 2016, European heart journal.

signaling RhoH is important for positive thymocyte selection and T-cell receptor

M. Sixt, J. Ellwart, K. Scharffetter-Kochanek, 2013 .

Patient-specific induced pluripotent stem-cell models for long-QT syndrome.

M. Seyfarth, A. Schömig, F. Hofmann, 2010, The New England journal of medicine.