A. Slater

发表

Malaria-specific metabolite hemozoin mediates the release of several potent endogenous pyrogens (TNF, MIP-1 alpha, and MIP-1 beta) in vitro, and altered thermoregulation in vivo.

K. Tracey, A. Cerami, B. Sherry, 1995, Journal of inflammation.

Rapid and Specific Efflux of Reduced Glutathione during Apoptosis Induced by Anti-Fas/APO-1 Antibody*

S. Orrenius, I. Cotgreave, D. J. van den Dobbelsteen, 1996, The Journal of Biological Chemistry.

Mechanism of dithiocarbamate inhibition of apoptosis: thiol oxidation by dithiocarbamate disulfides directly inhibits processing of the caspase-3 proenzyme.

D. H. Burgess, B. Zhivotovsky, S. Orrenius, 1997, Chemical research in toxicology.

Dithiocarbamates Induce Apoptosis in Thymocytes by Raising the Intracellular Level of Redox-active Copper (*)

S. Orrenius, B. Lind, A. Slater, 1995, The Journal of Biological Chemistry.

Disulfiram is a potent inhibitor of proteases of the caspase family.

S. Orrenius, D. Nicholson, A. Slater, 1997, Chemical research in toxicology.

Dithiocarbamate toxicity toward thymocytes involves their copper-catalyzed conversion to thiuram disulfides, which oxidize glutathione in a redox cycle without the release of reactive oxygen species.

S. Orrenius, S. Tsang, M. Burkitt, 1998, Archives of biochemistry and biophysics.

Chloroquine: mechanism of drug action and resistance in Plasmodium falciparum.

A F Slater, A. Slater, 1993, Pharmacology & therapeutics.

Malaria pigment.

A. Slater, 1992, Experimental parasitology.

Effects of N-acetyl-L-cysteine on T-cell apoptosis are not mediated by increased cellular glutathione.

Dean P. Jones, S. Orrenius, D. P. Jones, 1995, Immunology letters.

The role of intracellular oxidants in apoptosis.

S. Orrenius, A. Slater, C. Nobel, 1995, Biochimica et biophysica acta.

Intracellular redox changes during apoptosis.

S. Orrenius, D. J. van den Dobbelsteen, A. Slater, 1996, Cell death and differentiation.

Inhibition of Na+/K+-ATPase may be one mechanism contributing to potassium efflux and cell shrinkage in CD95-induced apoptosis

J. Aronson, D. J. van den Dobbelsteen, A. Slater, 2000, Apoptosis.

Nitrone spin traps and a nitroxide antioxidant inhibit a common pathway of thymocyte apoptosis.

S. Orrenius, E. Maellaro, J. Bustamante, 1995, The Biochemical journal.

Importance of the redox state of cytochrome c during caspase activation in cytosolic extracts.

D. H. Burgess, B. Zhivotovsky, S. Orrenius, 1998, The Biochemical journal.

Regulation and Mechanisms of Apoptosis in T Lymphocytes

S. Orrenius, A. Slater, C. Nobel, 1997 .

Epidemiology and immunology of Necator americanus infection in a community in Papua New Guinea: humoral responses to excretory-secretory and cuticular collagen antigens

D. Pritchard, P. McKean, R. Quinnell, 1990, Parasitology.

Antioxidant inhibition of thymocyte apoptosis by dihydrolipoic acid.

S. Orrenius, J. Bustamante, A. Slater, 1995, Free radical biology & medicine.

The influence of dietary protein on the experimental epidemiology of Heligmosomoides polygyrus (Nematoda) in the laboratory mouse

A. Slater, 1988, Proceedings of the Royal Society of London. Series B. Biological Sciences.

Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites

A. Cerami, A. Slater, 1992, Nature.

The influence of protein deficiency on immunity to Heligmosomoides polygyrus (Nematoda) in mice

A. Slater, A. Keymer, A.E. KEYMER, 1988, Parasite immunology.

Heligmosomoides polygyrus (Nematoda): the influence of dietary protein on the dynamics of repeated infection

A. Slater, A. Keymer, Anne E. Keymer, 1986, Proceedings of the Royal Society of London. Series B. Biological Sciences.

Epidemiology of Heligmosomoides polygyrus in mice: experiments on natural transmission

A. Slater, A. Keymer, 1986, Parasitology.

An iron-carboxylate bond links the heme units of malaria pigment.

D. Goldberg, A. Cerami, G. Henderson, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Hemoglobin degradation in the malaria parasite Plasmodium falciparum: an ordered process in a unique organelle.

D. Goldberg, A. Cerami, G. Henderson, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Signalling mechanisms and oxidative stress in apoptosis.

S. Orrenius, D. J. van den Dobbelsteen, A. Slater, 1995, Toxicology letters.

Oxidative stress and apoptosis

S. Orrenius, A. Slater, 1995 .

Inhibition of Hemozoin Formation in Plasmodium falciparum Trophozoite Extracts by Heme Analogs: Possible Implication in the Resistance to Malaria Conferred by the β-Thalassemia Trait

A. Cerami, J. Martiney, A. Slater, 1996, Molecular medicine.

The population dynamics of acquired immunity to helminth infection.

J. Murray, C. Berding, A. Slater, 1986, Journal of theoretical biology.

The epidemiological significance of the immune response to the cuticular collagen of Necator americanus: a preliminary study in a hookworm-endemic area in Papua New Guinea.

D. Pritchard, P. McKean, R. Quinnell, 1990, Acta tropica.

Reinfection with hookworm after chemotherapy in Papua New Guinea

D. Pritchard, P. Tighe, R. Quinnell, 1993, Parasitology.

Low rate of reinfection with Enterobius vermicularis in a Papua New Guinea village.

D. Pritchard, P. Tighe, R. Quinnell, 1994, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Antigenic cross-reactivity between Necator americanus and Ascaris lumbricoides in a community in Papua New Guinea infected predominantly with hookworm.

D. Pritchard, P. McKean, R. Quinnell, 1991, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Hookworm (Necator americanus) infection and storage iron depletion.

D. Pritchard, P. McKean, R. Quinnell, 1991, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Helminth fecundity: density dependence or statistical illusion?

A. Slater, A. Keymer, 1987, Parasitology today.

Dithiocarbamates and the redox regulation of cell death.

S. Orrenius, M. Burkitt, D. J. van den Dobbelsteen, 1996, Biochemical Society transactions.

Verapamil Reversal of Chloroquine Resistance in the Malaria Parasite Plasmodium falciparum Is Specific for Resistant Parasites and Independent of the Weak Base Effect (*)

A. Cerami, J. Martiney, A. Slater, 1995, The Journal of Biological Chemistry.

Hemoglobin degradation in the human malaria pathogen Plasmodium falciparum: a catabolic pathway initiated by a specific aspartic protease

B. Chait, D. Goldberg, R. Beavis, 1991, The Journal of experimental medicine.

The pathway of hemoglobin degradation in malaria parasites.

D. Goldberg, A. Slater, 1992, Parasitology today.

The population dynamics of acquired immunity to helminth infection: experimental and natural transmission.

J. Murray, C. Berding, A. Slater, 1987, Journal of theoretical biology.

Chloroquine resistance is not associated with drug metabolism in Plasmodium falciparum.

B. Berger, A. Cerami, J. Martiney, 1995, The Journal of parasitology.

Regulation and mechanisms of apoptosis in T lymphocytes.

S. Orrenius, D. J. van den Dobbelsteen, A. Slater, 1996, Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement.

Constitutive nuclear NF kappa B/rel DNA-binding activity of rat thymocytes is increased by stimuli that promote apoptosis, but not inhibited by pyrrolidine dithiocarbamate.

S. Orrenius, A. Slater, S. Jiang, 1995, The Biochemical journal.